Yuanke Zhang, Rui Zhang, Rujuan Cao, Fan Xu, Fengjuan Jiang, Jing Meng, Fei Ma, Yanfei Guo, Jianlei Liu
BACKGROUND AND OBJECTIVE: Low-dose computed tomography (LDCT) scans significantly reduce radiation exposure, but introduce higher levels of noise and artifacts that compromise image quality and diagnostic accuracy. Supervised learning methods have proven effective in denoising LDCT images, but are hampered by the need for large, paired datasets, which pose significant challenges in data acquisition. This study aims to develop a robust unsupervised LDCT denoising method that overcomes the reliance on paired LDCT and normal-dose CT (NDCT) samples, paving the way for more accessible and practical denoising techniques...
May 3, 2024: Computer Methods and Programs in Biomedicine