Shenpan Li, LuYin Wu, HuiXian Zeng, Jing Zhang, ShuangJian Qin, Li-Xia Liang, John Andersson, Wen-Jie Meng, Xing-Yu Chen, Qi-Zhen Wu, Li-Zi Lin, Wei-Chun Chou, Guang-Hui Dong, Xiao-Wen Zeng
Chlorinated polyfluorinated ether sulfonate (F-53B), a substitute of perfluorooctane sulfonic acid (PFOS), has attracted significant attention for its link to hepatotoxicity and enterotoxicity. Nevertheless, the underlying mechanisms of F-53B-induced enterohepatic toxicity remain incompletely understood. This study aimed to explore the role of F-53B exposure on enterohepatic injury based on the gut microbiota, pathological and molecular analysis in mice. Here, we exposed C57BL/6 mice to F-53B (0, 4, 40, and 400 μg/L) for 28 days...
January 31, 2024: Environmental Research