Shane P Stenner, Rohini Chakravarthy, Kevin B Johnson, William L Miller, Julie Olson, Marleen Wickizer, Nate N Johnson, Rick Ohmer, David R Uskavitch, Gordon R Bernard, Erin B Neal, Christoph U Lehmann
INTRODUCTION: Spending on pharmaceuticals in the US reached $373.9 billion in 2014. Therapeutic interchange offers potential medication cost savings by replacing a prescribed drug for an equally efficacious therapeutic alternative. METHODS: Hard-stop therapeutic interchange recommendation alerts were developed for four medication classes (HMG-CoA reductase inhibitors, serotonin receptor agonists, intranasal steroid sprays, and proton-pump inhibitors) in an electronic prescription-writing tool for outpatient prescriptions...
December 14, 2016: Applied Clinical Informatics