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self-healing dental composite

Jun-Ling Wu, Tong Li, Xu Gao, Qiang Zhang, Di Liu, Jian-Hua Ge, Chuan-Jian Zhou
OBJECTIVE: This investigation aimed to develop a novel self-healing and antibacterial dental resin composite. The effects of water immersion on its properties were also evaluated. METHODS: Microcapsules filled with healing agent of triethylene glycol dimethacrylate were synthesized on the basis of previous studies. Antibacterial resin composite contained nano-antibacterial inorganic fillers that were modified by quaternary ammonium salt with long-chain alkyl. Microcapsules were incorporated into antibacterial resin composite at mass fraction of 7...
October 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
Ali H Tayeb, Ezatollah Amini, Shokoofeh Ghasemi, Mehdi Tajvidi
Cellulose nanomaterials (CNs) are of increasing interest due to their appealing inherent properties such as bio-degradability, high surface area, light weight, chirality and the ability to form effective hydrogen bonds across the cellulose chains or within other polymeric matrices. Extending CN self-assembly into multiphase polymer structures has led to useful end-results in a wide spectrum of products and countless innovative applications, for example, as reinforcing agent, emulsion stabilizer, barrier membrane and binder...
October 18, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Mobin Yahyazadehfar, George Huyang, Xiaohong Wang, Yuwei Fan, Dwayne Arola, Jirun Sun
Durability is an important quality of dental restorative materials, and the ability to autonomously heal damage incurred during their oral function is highly desirable. OBJECTIVE: The objective was to evaluate the improvement in durability of self-healing dental composites (SHDCs) in terms of their resistance to fracture and capacity for healing of damage under monotonic and cyclic loading. METHODS: SHDCs were prepared by incorporating dental resin composites with microcapsules containing healing liquid...
December 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
H Y Yan, H Y Yang, C Huang
Degradation of composite resin during ageing always produces micro-cracks, the latter could gradually expand, leading to the fracture of tooth restoration. In order to extend the service life of composite resin by repairing cracks intelligently, self-healing microcapsule models have been introduced in resin-based dental materials. This paper will present the concept and classification of self-healing materials, and review the research progresses on self-healing dental resin.
September 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
Shichao Yue, Junling Wu, Qiang Zhang, Ke Zhang, Michael D Weir, Satoshi Imazato, Yuxing Bai, Hockin H K Xu
OBJECTIVES: Secondary caries at the tooth-restoration margins is a primary reason for restoration failure. Cracks at the margins lead to leakage which can trap bacteria, producing acids to cause caries. To date, there has been no report on developing an adhesive resin that has self-healing, antibacterial and remineralizing capabilities. The objectives of this study were to: (1) develop the first self-healing adhesive with antimicrobial and remineralizing capabilities, and (2) investigate the effects of incorporating microcapsules, dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of amorphous calcium phosphate (NACP) for the first time...
August 2018: Journal of Dentistry
Mariel Soeiro Maas, Yvette Alania, Livia Camargo Natale, Marcela Charantola Rodrigues, David Christopher Watts, Roberto Ruggiero Braga
Clinical trials have identified secondary caries and bulk fracture as the main causes for composite restoration failure. As a measure to avoid frequent reinterventions for restoration replacement, composites with some sort of defense mechanism against biofilm formation and demineralization, as well as materials with lower susceptibility to crack propagation are necessary. Also, the restorative procedure with composites are very time-consuming and technically demanding, particularly concerning the application of the adhesive system...
August 28, 2017: Brazilian Oral Research
Chen Chen, Junling Wu, Michael D Weir, Lin Wang, Xuedong Zhou, Hockin H K Xu, Mary Anne S Melo
Fracture and secondary caries are the primary reasons for the failure of dental restorations. To face this omnipresent problem, we report the formulation design and synthesis of a protein-resistant dental composite composed of 2-methacryloyloxyethyl phosphorylcholine (MPC) that also can self-repair damage and recover the load-bearing capability via microencapsulated triethylene glycol dimethacrylate (TEGDMA) and N,N-dihydroxy ethyl-p-toluidine (DHEPT). The bioactivity of the resulting MPC-microencapsulated TEGDMA-DHEPT was evaluated on protein adsorption through early bacterial attachment...
September 7, 2017: Journal of Functional Biomaterials
Mayo Takada, Masaya Suzuki, Maiko Haga-Tsujimura, Koichi Shinkai
We examined the effects of adhesive systems under study applied for a laser-cut cavity using an Er,Cr:YSGG laser on rat dental pulp at 24 h and 14 days postoperatively. Group 1, laser-cut cavities were treated with a self-etching-primer and bonding agent; group 2, pretreated with a phosphoric-acid, and then treated with a self-etching-primer and bonding agent; group 3, pretreated with a phosphoric-acid and sodium-hypochlorite, and then treated with a self-etching-primer and bonding agent; and group 4, treated with an all-in-one adhesive...
July 2017: Odontology
Farah Masood, Jason Nicholson, Joy Beckerley, Hui Liang, Lida Radfar
OBJECTIVES: To study the radiographic mean grey values after bone grafting and to clinically evaluate the intraoral alveolar ridge dimensional stability with anorganic bovine bone mineral (ABBM) particulate and a patented self-expanding composite graft (SECG) after 6 months of healing. METHODS: A total of 20 single-rooted tooth-extraction sites grafted with either ABBM or SECG were evaluated radiographically and clinically after 6 months of healing, prior to dental implant placement...
September 2016: Compendium of Continuing Education in Dentistry
George Huyang, Anne E Debertin, Jirun Sun
The purpose of this project is to design and develop a clinically applicable self-healing dental composite (SHDC). The value of resin-based dental restorations could be improved by increasing their service lives. One way to improve longevity is to obturate micro-cracks that form during or after the composite hardens in the dental cavity. Toward this end, we introduce here a new type of SHDC made with contemporary dental components plus two additional ingredients: a healing powder (HP, strongtium fluoroaluminosilicate particles) and a healing liquid (HL, aqueous solutions of polyacrylic acids) that is enclosed within silica microcapsules...
March 15, 2016: Materials & Design
Junling Wu, Michael D Weir, Mary Anne S Melo, Howard E Strassler, Hockin H K Xu
OBJECTIVES: The objectives of this study were to develop a self-healing dental composite containing poly(urea-formaldehyde) (PUF) shells with triethylene glycol dimethacrylate (TEGDMA) and N,N-dihydroxyethyl-p-toluidine (DHEPT) as healing liquid, and to investigate the mechanical properties of the composite and its self-healing efficacy after water-aging for 6 months. METHODS: PUF microspheres were synthesized encapsulating a TEGDMA-DHEPT healing liquid. Composite containing 30% of a resin matrix and 70% of glass fillers by mass was incorporated with 0%, 2...
April 2016: Journal of Dentistry
Junling Wu, Michael D Weir, Qiang Zhang, Chuanjian Zhou, Mary Anne S Melo, Hockin H K Xu
OBJECTIVE: Bulk fracture is one of the primary reasons for resin-based dental restoration failures. To date, there has been no report on the use of polymerizable dental monomers with acceptable biocompatibility to develop a resin with substantial self-healing capability. The objectives of this study were to: (1) develop a self-healing resin containing microcapsules with triethylene glycol dimethacrylate (TEGDMA)-N,N-dihydroxyethyl-p-toluidine (DHEPT) healing liquid in poly(urea-formaldehyde) (PUF) shells for the first time, and (2) determine the physical and mechanical properties, self-healing efficiency, and fibroblast cytotoxicity...
February 2016: Dental Materials: Official Publication of the Academy of Dental Materials
Giselle C Yeo, Behnaz Aghaei-Ghareh-Bolagh, Edwin P Brackenreg, Matti A Hiob, Pearl Lee, Anthony S Weiss
The mechanical stability, elasticity, inherent bioactivity, and self-assembly properties of elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The ability to engineer specific peptide sequences derived from elastin allows the precise control of these physicochemical and organizational characteristics, and further broadens the diversity of elastin-based applications. Elastin and elastin-like peptides can also be modified or blended with other natural or synthetic moieties, including peptides, proteins, polysaccharides, and polymers, to augment existing capabilities or confer additional architectural and biofunctional features to compositionally pure materials...
November 18, 2015: Advanced Healthcare Materials
Junling Wu, Michael D Weir, Mary Anne S Melo, Hockin H K Xu
OBJECTIVES: Fracture and secondary caries are the primary reasons for dental restoration failure. The objective of this study was to develop a self-healing composite to heal cracks, while containing dimethylaminohexadecyl methacrylate (DMAHDM) for antibacterial function and nanoparticles of amorphous calcium phosphate (NACP) for remineralization. METHODS: Microcapsules were synthesized with poly(urea-formaldehyde) (PUF) shells containing triethylene glycol dimethacrylate (TEGDMA) and N,N-dihydroxyethyl-p-toluidine (DHEPT) as healing liquid...
March 2015: Journal of Dentistry
(no author information available yet)
No abstract text is available yet for this article.
2014: HDA Now
Xin Wang, Yu Wang, Wenlong Gou, Qiang Lu, Jiang Peng, Shibi Lu
Mesenchymal stem cells (MSCs) are non-haematopoietic stromal stem cells that have many sources, such as bone marrow, periosteum, vessel walls, adipose, muscle, tendon, peripheral circulation, umbilical cord blood, skin and dental tissues. They are capable of self-replication and of differentiating into, and contributing to the regeneration of, mesenchymal tissues, such as bone, cartilage, ligament, tendon, muscle and adipose tissue. The homing of MSCs may play an important role in the repair of bone fractures...
December 2013: International Orthopaedics
Xiaobai Ouyang, Xueqing Huang, Qiuhua Pan, Chenqi Zuo, Cui Huang, Xiangliang Yang, Yanbing Zhao
OBJECTIVES: To date, the production of highly durable dentine bonding is still a challenge. Self-healing bonding resins may provide a new direction for the improvement of the bonding durability. The objective of the current study was to synthesize polyurethane nanocapsules encapsulated with the core material triethylene glycol dimethacrylate (TEGDMA) for use as a major component in a self-healing bonding resin. METHODS: TEGDMA nanocapsules were synthesized via interfacial polycondensation in a miniemulsion, and the TEGDMA nanocapsules were then characterized via Fourier-transform infrared (FTIR) spectrometer, field emission scanning electron microscopy (FESEM), and high-performance liquid chromatography (HPLC) to investigate the morphology, the average TEGDMA loading (DL%), and encapsulation efficiency (EE%)...
December 2011: Journal of Dentistry
Akhilesh K Gaharwar, Christian P Rivera, Chia-Jung Wu, Gudrun Schmidt
The structures and mechanical properties of both physically and covalently cross-linked nanocomposite hydrogels made from poly(ethylene glycol) (PEG) and silicate nanoparticles (Laponite RD) are investigated. Injectable nanocomposite precursor solutions can be covalently cross-linked via photopolymerization. The resulting hydrogels are transparent and have interconnected pores, high elongation and toughness. These properties depend on the hydrogel composition, polymer-nanoparticle interactions and degree of cross-linking (both physical and covalent)...
December 2011: Acta Biomaterialia
Stefanie Feierabend, Yvonne Jockel-Schneider, Bernd Klaiber
The aim of this case report was to present a treatment strategy for severely injured teeth in children and adolescents by using periodontal surgery and adhesive techniques. A 16-year-old boy presented after a severe bicycle accident. A radiograph revealed a root fracture with connective tissue healing and displacement. Clinically, a crown-root fracture as well as an uncomplicated crown fracture of the same fragment was obvious. The root canal was prepared and filled with gutta-percha to the fracture line. A full periodontal flap was performed, and the crown-root fragment was adhesively fixed...
March 2011: Quintessence International
Daniela Carmagnola, Silvio Abati, Silvio Celestino, Matteo Chiapasco, Dieter Bosshardt, Niklaus P Lang
OBJECTIVES: To compare the histological features of bone filled with Bio-Oss, Ostim-Paste or PerioGlas placed in defects in the rabbit tibiae by evaluating bone tissue composition and the integration of titanium implants placed in the grafted bone. MATERIAL AND METHODS: Two cylindrical bone defects, about 4 mm in diameter and 6 mm in depth, were created in the tibiae of 10 rabbits. The defects were filled with either Bio-Oss, PerioGlas, Ostim-Paste or left untreated, and covered with a collagen membrane...
December 2008: Clinical Oral Implants Research
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