Yansong Liu, Mingcui Li, Zhengbo Fang, Shan Gao, Weilun Cheng, Yunqiang Duan, Xuelian Wang, Jianyuan Feng, Tianshui Yu, Jiarui Zhang, Ting Wang, Anbang Hu, Hanyu Zhang, Zhiyuan Rong, Suborna S Shakila, Yuhang Shang, Fanjing Kong, Jiangwei Liu, Yanling Li, Fei Ma
BACKGROUND: Estrogen receptor (ER) positive human epidermal growth factor receptor 2 (HER2) negative breast cancer (ER+/HER2-BC) and triple-negative breast cancer (TNBC) are two distinct breast cancer molecular subtypes, especially in tumor immune microenvironment (TIME). The TIME of TNBC is considered to be more inflammatory than that of ER+/HER2-BC. Natural killer (NK) cells are innate lymphocytes that play an important role of tumor eradication in TME. However, studies focusing on the different cell states of NK cells in breast cancer subtypes are still inadequate...
May 7, 2024: Cancer Immunology, Immunotherapy: CII