Johanna Nattenmüller, Christopher L Schlett, Nanae Tsuchiya, Scott B Reeder, Perry J Pickhardt, Harald Kramer, Hans-Ulrich Kauczor, Mark O Wielpütz, Joon B Seo, Hiroto Hatabu, Edwin J R van Beek, Mark L Schiebler
The purpose of this review article is to acquaint the reader with the current state of the art for the noncardiovascular imaging biomarkers of metabolic syndrome found on noncontrast computed tomography (NCCT) of the chest and their prognostic significance. Routine chest NCCT includes quantitative information with regard to tissue density and organ volumes in the neck, chest, and upper abdomen. The specific imaging biomarkers that may be seen in association with metabolic syndrome include low thyroid iodine organification, hepatic steatosis, sarcopenia (muscle volume and density), demineralization of the thoracic and upper lumbar vertebral bodies, loss of axial skeletal muscle mass, premature lung inflammation, and an increased deposition of subcutaneous and visceral fat...
March 2019: Journal of Thoracic Imaging