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PLLA threads

Chang Min Kim, Bo Young Kim, Dong Hye Suh, Sang Jun Lee, Hye Rim Moon, Hwa Jung Ryu
BACKGROUND: There are many collagen-stimulating fillers, including calcium hydroxyapatite, polycaprolactone (PCL), and poly-L-lactic acid (PLLA), and other materials have been tested. Polydioxanone (PDO) has recently been used as absorbable thread-lifting material due to its collagen-forming effects. PDO in powdered form is expected to be a good material for collagen-producing fillers. OBJECTIVES: To evaluate the collagen-producing effects of powdered PDO injection compared with PLLA injection in a murine model...
February 27, 2019: Journal of Cosmetic Dermatology
Yelda Kapicioğlu, Mehmet Gül, Gülbahar Saraç, Birgül Yiğitcan, Harika Gözükara
BACKGROUND: Polydioxanone Cog thread and poly-L-lactic acid (PLLA) thread have been used clinically for lifting and antiaging purposes. However, the histological changes in tissue and the efficacy of these 2 different types of thread have not been compared. OBJECTIVE: This study used hematoxylin and eosin (H&E) staining, Masson's trichrome staining, and electron microscopy (EM) to compare the results associated with the use of Cog thread and PLLA thread in rat skin...
January 2, 2019: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Stefania Guida, Flavia Persechino, Giuseppe Rubino, Giovanni Pellacani, Francesca Farnetani, Giacomo Giovanni Urtis
BACKGROUND: The request for less-aggressive procedures to improve mandibular contour is increasing. Several kinds of threads have been used for this purpose. Nevertheless, PLLA (poly-L-Lactic acid) traction thread procedure has not been previously described. AIM: To investigate the role of PLLA traction threads in improving mandibular contour. METHODS: Twenty women were enrolled in the study. They were differentially classified for skin laxity...
February 20, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Soshi Uchida, Moriyuki Noguchi, Hajime Utsunomiya, Shiho Kanezaki, Toshiharu Mori, Dean K Matsuda, Akinori Sakai
PURPOSE: The purposes of this study were to investigate (1) the clinical, radiographic and arthroscopic presentation of patients with subchondral insufficiency fracture of the femoral head (SIFFH) and (2) the outcomes following arthroscopic treatment with internal fixation using hydroxyapatite poly-lactate acid (HA/PLLA) threaded pins and concomitant arthroscopic treatment of associated findings. METHODS: Nine patients (median age 49.0 years, range 43-65, five female and four male patients) with SIFFH who underwent arthroscopic treatment with labral repair, capsular closure and internal fixation of SIFFH using HA/PLLA pins were retrospectively reviewed...
August 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Shuichi Ogino, Naoki Morimoto, Michiharu Sakamoto, Chizuru Jinno, Katsuhiro Yoshikawa, Tatsuki Enoshiri, Yuki Sakamoto, Tsuguyoshi Taira, Shigehiko Suzuki
Recently, adipose tissue has been regenerated by combining scaffolds, growth factors, and/or adipose-tissue-derived stromal cells. However, the safety of growth factors and adipose-tissue-derived stromal cells has not been confirmed in cancer patients. We reported the regeneration of adipose tissue in the internal space of a polypropylene mesh containing a collagen sponge (CS), without using any growth factors or cells. We herein explored the formation of adipose tissue, using the bioabsorbable implant containing CS, in rats...
March 2018: Journal of Tissue Engineering and Regenerative Medicine
Pei Han, Pengfei Cheng, Shaoxiang Zhang, Changli Zhao, Jiahua Ni, Yuanzhuang Zhang, Wanrun Zhong, Peng Hou, Xiaonong Zhang, Yufeng Zheng, Yimin Chai
High-purity magnesium (HP Mg) takes advantage in no alloying toxic elements and slower degradation rate in lack of second phases and micro-galvanic corrosion. In this study, as rolled HP Mg was fabricated into screws and went through in vitro immersion tests, cytotoxicity test and bioactive analysis. The HP Mg screws performed uniform corrosion behavior in vitro, and its extraction promoted cell viability, bone alkaline phosphatase (ALP) activity, and mRNA expression of osteogenic differentiation related gene, i...
September 2015: Biomaterials
Anis Abdul Karim, Xian Jun Loh
In recent years supramolecular structures built from macrocyclic compounds have attracted tremendous interest due to the unique properties derived from dynamic self-assembly. Our study proposes a two-step mechanism to form a supramolecular hydrogel system: (1) the formation of micelles, and (2) micelle association with α-cyclodextrin (α-CD) due to threading of PEGMA in the α-CD cavity, forming inclusion complexes. Using this mechanism, a supramolecular hydrogel made from a tri-component copolymer PLLA/DMAEMA/PEGMA and α-CD was fabricated for the first time and characterized in terms of its structural, morphological, and rheological properties...
July 21, 2015: Soft Matter
Soshi Uchida, Hajime Utsunomiya, Tomonori Taketa, Shinsuke Sakoda, Akihisa Hatakeyama, Toshitaka Nakamura, Akinori Sakai
BACKGROUND: Various procedures, such as arthroscopic debridement, osteochondral transplantation, and bone plug fixation, have been described for the treatment of osteochondritis dissecans (OCD) of the humeral capitellum. However, the use of hydroxyapatite/poly-L-lactate acid (HA/PLLA) thread pins to fix the osteochondral fragment in an OCD lesion is a recent development. HYPOTHESIS: Adolescent throwing athletes would return to preinjury levels of function after arthroscopic osteochondral fragment fixation using HA/PLLA thread pins...
May 2015: American Journal of Sports Medicine
Naoya Takada, Takanobu Otsuka, Hiroyuki Suzuki, Kunio Yamada
OBJECTIVES: The purpose of this report is to present our surgical technique using forged composites of unsintered hydroxyapatite particles/poly-L-lactide (F-u-HA/PLLA) pins for pediatric displaced fractures of the lateral condyle of the humerus, to retrospectively evaluate clinical outcomes, and to verify the advantages of this device by using postoperative radiographs. DESIGN: Retrospective (level IV) case series. SETTING: Academic medical center...
May 2013: Journal of Orthopaedic Trauma
Chunbo Jiang, Zongbao Wang, Haiying Huang, Tianbai He
A large number of lozenge-shaped and sandwiched polystyrene-block-poly(L-lactide) (PS-b-PLLA) single crystals were prepared by the self-seeding technique. The single crystals were nearly monodispersed in both thickness and diameter. They are well-dispersed because of the steric stabilization offered by tethered PS in p-xylene, which is a good solvent for PS. The suspensions were observed to separate into a transparent upper phase and a turbid lower phase. The lower phase showed uniform iridescent stripes extending over the whole tube between crossed polarizers...
April 19, 2011: Langmuir: the ACS Journal of Surfaces and Colloids
Jon Olav Drogset, Lene Granrud Straume, Ingrid Bjørkmo, Gunnar Myhr
INTRODUCTION: Bioabsorbable screws are, at the expense of metal screws, increasingly used as fixation device in ACL-reconstructions. The possible advantages with bioabsorbable screws are better postoperative MRI evaluations and easier revision surgery. PURPOSE: The aim of this study was to compare the clinical outcome after ACL-reconstructions with BPTB-grafts fixed with metal interference screws or bioabsorbable screws 7 years postoperatively. The resorption of the bioabsorbable screws was also analyzed...
May 2011: Knee Surgery, Sports Traumatology, Arthroscopy
Chuang-Long He, Zheng-Ming Huang, Xiao-Jian Han
In this work, drug-loaded fibers and threads were successfully fabricated by combining electrospinning with aligned fibers collection. Two different electrospinning processes, that is, blend and coaxial electrospinning, to incorporate a model drug tetracycline hydrochloride (TCH) into poly(L-lactic acid) (PLLA) fibers have been used and compared with each other. The resulting composite ultrafine fibers and threads were characterized through scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, and tensile testing...
April 2009: Journal of Biomedical Materials Research. Part A
John A Hunt, Jill T Callaghan
The aim of the study was to assess the hard tissue response of a composite hydroxyapatite/poly L-lactic acid (HA/PLLA) interference screw for anterior cruciate ligament (ACL) reconstruction compared to a standard PLLA screw. Twelve skeletally mature rams underwent unilateral ACL reconstruction using an autologous bone-patellar tendon graft. Each animal received either two test HA/PLLA interference screws or two control PLLA interference screws. Animals were sacrificed at 6 and 12 months post-implantation and the operated knees excised...
July 2008: Knee Surgery, Sports Traumatology, Arthroscopy
F Alan Barber, W Dee Dockery
PURPOSE: To evaluate the long term in vivo degradation of poly-L-lactic acid (PLLA) interference screws with computed tomography (CT) and radiography as used in patellar tendon autograft anterior cruciate ligament (ACL) reconstruction. METHODS: A total of 20 patients who had undergone patellar tendon autograft ACL reconstruction fixed with PLLA screws at least 7 years earlier were evaluated by physical examination, radiography, and CT to determine whether PLLA screw reabsorption and bone ingrowth had occurred...
August 2006: Arthroscopy
Wenjian Guo, Ke Liu, Guilu Zhuang, Zefeng Chen, Tianming Guo
OBJECTIVE: To assess the treatment effect of intra-articular fracture with absorbable screws and rods. METHODS: From June 1998 to August 2004, 35 patients with intra-articular fracture were treated by absorbable screws and rods made of self-reinforced polyglycolic acid (SR-PGA) and self-reinforced poly-L-Lactic acid (SR-PLLA). Of 35 patients, 30 were males and 5 were females (aged from 4 to 62 years). All cases had intra-articular or periarticular fracture. The interval between injury and operation was 3 hours to 29 days...
March 2006: Chinese Journal of Reparative and Reconstructive Surgery
Barry L Eppley, Louis Morales, Robert Wood, Jay Pensler, Jeff Goldstein, Robert J Havlik, Mutaz Habal, Albert Losken, J Kerwin Williams, Fernando Burstein, Arlene A Rozzelle, A Michael Sadove
The need to provide rigid bony fixation in the surgical treatment of craniofacial deformities has inspired an on-going evolution of surgical innovations and implants. Because of the young age of many treated craniosynostosis patients and the unique pattern of cranial vault growth, the extensive implantation of metal devices is potentially problematic. The use of resorbable plate and screw devices offers all of the benefits of rigid fixation without many of their potential risks. Since the introduction of resorbable plate and screw devices in 1996, tens of thousands of craniofacial patients have received implants, but long-term results from a large series have yet to be reported...
September 15, 2004: Plastic and Reconstructive Surgery
T Pohjonen, P Helevirta, P Törmälä, K Koskikare, H Pätiälä, P Rokkanen
The effect of the manufacturing method on the strength retention of self-reinforced poly-L-lactide (SR-PLLA) screws was studied in vitro and in vivo from 3 up to at least 15 weeks. SR-PLLA screws were manufactured from axially oriented SR-PLLA billets by the conventional compression moulding process and an in-house developed machine cutting technique. New machined SR-PLLA screws (thread diameters 4.5 mm and 3.5 mm) were significantly stronger than older compression moulded SR-PLLA screws (4.5 mm and 3.5 mm) in bending and torque strength tests but significantly weaker in shear strength tests...
May 1997: Journal of Materials Science. Materials in Medicine
Nobuyuki Tanaka, Kazuya Hirose, Hisashi Sakahashi, Takumi Ishima, Seiichi Ishii
BACKGROUND: Bioabsorbable thread pin has been used for internal fixation of bone. The results of resection arthroplasty of the lesser metatarsophalangeal (MTP) joints using internal intramedullary fixation with bioabsorbable pins have not been reported. METHODS: Resection arthroplasty of the MTP joints of the lesser toes with poly-L-lactic acid (PLLA) thread pins or Kirschner wires was performed at random in reconstruction of the 87 rheumatoid forefeet (62 patients) with a grommet-protected silicone-rubber implant insertion of the first MTP joint...
July 2004: Foot & Ankle International
Koji Totoribe, Masanori Matsumoto, Vijay K Goel, S J Yang, Naoya Tajima, Yasuo Shikinami
STUDY DESIGN: A new cage made from a forged composite of unsintered hydroxyapatite particles and poly-L-lactide (F-u-HA/PLLA) is compared biomechanically with the Ray threaded fusion cage. OBJECTIVES: To compare the stability imparted to the human cadaveric spine by two different threaded cervical cages and the effect of cyclic loading on construct stability. SUMMARY OF BACKGROUND DATA: Threaded cages have been developed for use in anterior cervical interbody fusions to provide initial stability during the fusion process...
May 15, 2003: Spine
K Hattori, N Tomita, S Tamai, Y Ikada
The purpose of this research was to develop a bioabsorbable thread for tight fixation of fractured bones and to examine its mechanical performance in an in-vitro simulation study. The thread is a blend of bioabsorbable poly(L-lactic acid); (PLLA) and poly(epsilon-caprolactone); (PCL) fibers and can be tightly connected by fusion welding of the PCL fibers. The tying strength of the PLLA-PCL blend thread was 39.7 N, which was comparable to that of stainless steel wire. A testing machine was fabricated to measure the fatigue strength of the tying by simulating bone fixation...
2000: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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