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Pulmonary manifestations of temporal arteritis.

D Pinho Dos Santos, J P Fonseca, V Romão, J Capelo, A Carragoso
Giant Cell Arteritis (GCA) is a common systemic vasculitis that involves medium and large arteries, most frequently extracranial branches of the carotid artery. Prompt diagnosis and treatment is essential to prevent devastating complications, such as blindness, stroke and aortic aneurysm or dissection. Typical symptoms include headache, temporal artery tenderness and jaw claudication. On rare occasions patients present with complaints related to pulmonary involvement. These include interstitial infiltration, pulmonary nodules, pleural effusion and pulmonary haemorrhage...
February 9, 2019: Pulmonology
T F Imran, S Helfgott
OBJECTIVES: The classical presentation of giant cell arteritis (GCA) includes the new onset of headache, scalp tenderness, facial pain or jaw claudication in an older patient. Many patients with GCA have features consistent with the diagnosis of polymyalgia rheumatic (PMR) and nearly all have elevated markers of inflammation such as the erythrocyte sedimentation rate (ESR) or the serum C-reactive protein (CRP). Respiratory and ear-nose-throat (ENT) signs and symptoms such as cough, tongue infarction, trismus, hearing loss and facial swelling are less commonly described, yet they may be the initial presentation of GCA...
March 2015: Clinical and Experimental Rheumatology
Marina Titlić, Katica Kodzoman, Dragan Loncar
Hypereosinophilic syndrome is a rare disorder of the hematopoietic system. The disease is characterized by continuously high number of eosinophils (>1.5 x 10(9)/L) for more than six months. Other possible causes of hypereosinophilia, such as allergic and parasitic diseases, malignant disease, Churg-Strauss disease and infection should be eliminated. The most common manifestations of hypereosinophilic syndrome are pulmonary, skin, gastrointestinal, cardiac difficulties and neurologic lesions. Numerous neurologic lesions have been described, in particular of the central and peripheral nervous systems...
March 2012: Acta Clinica Croatica
P Dhaon, S K Das, R K Saran, A Parihar
A 23 year old female presented with dyspnea on exertion and absent pulses in the left upper limb. She had prior history of two first trimester abortions and pre-eclampsia with premature delivery. A Doppler examination had revealed left subclavian and axillary artery thrombosis for which she had been given warfarin six months previously. She was admitted and investigated. Patient had low positive aCL IgG antibody, positive antibeta2gp1 antibody, negative lupus anticoagulant and negative ANA. Patient had cardiomegaly and her echocardiography showed severe aortic regurgitation, moderate mitral regurgitation and moderate pulmonary artery hypertension with poor ejection fraction with normal aortic root...
December 2011: Lupus
Philippe Carassou, Marc Aletti, Gaël Cinquetti, Frédéric Banal, Cécile Landais, Bruno Graffin, Philippe Carli
BACKGROUND: Pleural and pulmonary manifestations of giant cell arteritis are rare and not well known. They can be associated to more typical signs of the disease and to an inflammatory biological syndrome which are comprised in the multisystemic manifestations of the disease. They can be inaugural, leading to a late management if unrecognized. METHODS: Retrospective and descriptive study of 8 cases over a 10 year period was conducted. Five females and three males with a 67-year-old average age were included according to the American College of Rheumatology criteria...
September 2010: La Presse Médicale
M T Miah, M A Hoque, S R Sutradhar, T Mahmood, B K Tarafder
Anti Phospholipid Syndrome (APS) is a relatively new conception of syndrome complex first noticed in 1983. It may be primary or secondary to other diseases like SLE, RA, Systemic sclerosis, behchet's syndrome, temporal arteritis, sjogren's syndrome psoriatic arthropathy etc. Clinical manifestations are consequences of vascular thrombosis and embolism like DVT, pulmonary embolism, stroke, TIA, complication of pregnancy with pregnancy loss. We report a 34 years married female housewife who presented with sudden onset of nausea, vomiting, vertigo, dysphagia, dysarthria and ataxia...
January 2009: Mymensingh Medical Journal: MMJ
M Kechaou, M Frigui, S Marzouk, M Jallouli, F Frikha, N Kaddour, T Boudawara, Z Bahloul
Pulmonary involvement is rare in Horton's disease. Only few cases have been reported presenting as interstitial infiltration, pulmonary artery vasculitis, pulmonary nodules and granulome formation. Pleural effusion was rarely reported. A 65-year-old male patient presented with a right pleural effusion. Horton's disease was evoked in the presence of cephalgias, an ocular involvement and general signs. Temporal artery biopsy showed giant cell arteritis. After negative etiologic work up, pleural effusion was attributed to Horton's disease...
November 2008: Revue Médicale de Liège
Isabelle Marie, Philippe Heliot, Jean-François Muir, Françis Roussel, Hervé Levesque, Hubert Courtois
Pulmonary involvement is considered to be rare in giant cell arteritis (GCA), usually occurring in the course of the disease. We describe the case of a patient who developed left pleural effusion revealing GCA. Thoracic CT scan demonstrated an abundant left pleural effusion and a thickening of the aortic wall. The patient's condition improved rapidly, with regression of pulmonary clinical features and complete clearance of pleural effusion, after institution of steroid therapy. Our case report reinforces the possibility of unusual presentation of GCA; such a diagnosis should, therefore, be considered in elderly patients presenting with pulmonary manifestations, even in the absence of typical clinical features of temporal arteritis (e...
April 2004: European Journal of Internal Medicine
T Le Tourneau, B Agraou, J P Beregi, C A Maurage, E P Asseman
Horton's disease is a giant cell arteritis well known for its presentation as temporal arteritis. It is, in fact, a systemic disease which affects over 1% of the general populations after 50 years of age. With the exception of the risk of blindness by occlusion of the ophthalmic artery, the cardiovascular manifestations of Horton's disease are not well known and probably underestimated by clinicians. The main complications are involvement of the large arteries, especially the thoracic aorta and subclavian and axillary arteries, the femoro-popliteal axis and supra-aortic arterial vessels...
October 1997: Archives des Maladies du Coeur et des Vaisseaux
Z Joomaye, A Sotto, J Jourdan
Pulmonary involvement is very rare in giant cell arteritis. The sign that is most often encountered seems to be dry cough which can remain, for a long time, the sole manifestation of this disease. We report a case of giant cell arteritis in a 66 year old woman that expressed for only symptom a dry cough during one year. A rapid regression of clinical symptoms and radiologic signs have been observed with steroid therapy. Presence of isolated cough along with biological marks of inflammation in a elderly patient should lead to temporal biopsy when no other evidence cause has been found...
January 1997: Revue des Maladies Respiratoires
H Gur, E Rapman, M Ehrenfeld, Y Sidi
OBJECTIVE: To examine the clinical manifestations of 39 patients with temporal (giant cell) arteritis (GCA), allocated during a 10 year period in the largest medical center in Israel. METHODS: The patients were included in the analysis if they fulfilled the new American College of Rheumatology Classification Criteria for the diagnosis of GCA. Patients were divided into biopsy-proven (30 patients) and biopsy-negative (9 patients) groups, and their clinical manifestations were compared using Student's t test for comparison of continuous variables, and Fisher's exact test for comparison of proportions...
November 1996: Journal of Rheumatology
D L Huong, C de Gennes, T Papo, B Wechsler, O Blétry, J C Piette, P Godeau
Pleuropulmonary manifestations of systemic vasculitis are common, polymorphic and of ambiguous significance: the same pulmonary lesion may reveal a specific manifestation of vasculitis as well as a therapy-induced complication, especially infection which may favor per se a flare-up. Two questions will be successively studied: what are the pleuropulmonary characteristics of Wegener's granulomatosis, Churg-Strauss syndrome, periarteritis nodosa, Behçet's disease, Takayasu's disease and temporal arteritis? What are the major adverse effects that may occur in the course of a treated systemic vasculitis?...
1996: La Revue de Médecine Interne
H Gur, M Ehrenfeld, E Izsak
Pulmonary involvement is rare in giant cell arteritis (GCA). Only a few cases have been reported, manifested by interstitial infiltration, pulmonary nodules, pulmonary artery vasculitis, and granuloma formation. Moreover, only 3 previous cases of pleural effusion associated with GCA have been described. Herein we report a 67-year-old woman with biopsy-proven temporal arteritis, presented with prolonged fever, weight loss, cough and pleural effusion. ELISA test for the presence of anti- proteinase-3 antibodies was negative...
March 1996: Clinical Rheumatology
S Deraedt, J Cabane, T Genereau, J C Imbert
Several respiratory manifestations have been described in patients with temporal arteritis. These complications may develop at the onset of the disease or later. Cough is the most frequent of them. Other complications include pleural effusions, interstitial pneumonitis, pulmonary vasculitis. Hyperreactive airways, hoarseness, diaphragm paralysis have been noted. Generally, corticosteroids cause a prompt improvement. Physicians should be aware of respiratory symptoms in patients with temporal arteritis in order to avoid delays in diagnosis and therapy...
1994: La Revue de Médecine Interne
T Zenone, P J Souquet, C Bohas, D Vital Durand, J P Bernard
The major manifestations of giant cell arteritis have been well described. Pulmonary manifestations, however, are rare. We report the case of a 75 year old woman with temporal arteritis, presenting with atypical manifestations, i.e. nodular pulmonary lesions, dry cough, rhinitis, conjunctivitis, and otitis with hearing loss. We conclude that overlapping features of giant cell arteritis and Wegener's granulomatosis occur in some patients.
December 1994: European Respiratory Journal
J D Bradley, R S Pinals, H B Blumenfeld, W M Poston
A patient presenting with polymyalgia rheumatica and biopsy-proved temporal arteritis showed response to corticosteroid therapy. Nodular pulmonary lesions developed twice, and diplopia and unilateral visual loss once, after reduction of the steroid dose. Response to reinstitution of full-dose steroids was dramatic. The clinical and pathologic findings in this patient suggest that the pulmonary lesions represented a previously undescribed manifestation of giant cell arteritis, but the possibility of limited Wegener's granulomatosis involving the temporal artery could not be ruled out...
July 1984: American Journal of Medicine
O Rodat, F Buzelin, M Weber, J Barrier, J L Harousseau, G Rodat, J Mussini-Montpellier
A 78 years old woman developed a pulmonary recurrence four years after the diagnosis of temporal arteritis. The lung biopsy showed the same giant-cells granulomatous lesions with central vessels as the initial biopsy. The recurrence in giant cells-arteritis has already been published but the pulmonary involvement had never been illustrated before by histological data. The difficulties of diagnosis in case of granulomatous angiitis on lung samples is emphasized.
September 1983: La Revue de Médecine Interne
J Modai, M Robineau, P Duroux, P Reynier, A Domart
No abstract text is available yet for this article.
November 1971: Journal Français de Médecine et Chirurgie Thoraciques
M R Kramer, E Melzer, G Nesher, M Sonnenblick
Temporal arteritis is a well-recognized multi-systemic disease. Pulmonary manifestations, however, are extremely rare. In two patients with biopsy-proven temporal arteritis, lung involvement was observed. One patient presented with multinodular pulmonary lesions, while the second had a diffuse interstitial pattern. Both patients responded well to corticosteroid treatment. In a review of the literature, only four additional cases associating lung involvement with temporal arteritis were found. The possibility of primary pulmonary vasculitis should be considered in elderly patients with temporal arteritis...
November 1987: European Journal of Respiratory Diseases
A Schwartz
An allergic disease may develop in any organ or system. The respective etiological factors include foreign proteins, infectious agents such as various microbes, viruses, moulds, parasites, chemical compounds often in the form of drugs usually designated as haptens, polysaccharides, benign and malignant neoplasms. Of the factors operating in the causal pathogenesis of such diseases the most important one is an exaggerated formation of antibodies, which appears to be uncontrolled and occurring irrespective of the demands of the organism...
1989: Acta Universitatis Carolinae. Medica. Monographia
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