Xueli Zhang, Xu Guo, Jinyue Sun, Yingying Chen, Mengqi Zhang, Xiaozhen Tang, Wenliang Wang, Jesus Simal-Gandara, Huiying Xu, Ningyang Li, Chao Liu
The limited application of garlic essential oil (GEO) is attributed to its pungent taste, poor water solubility and low bioavailability. Liposomes are nontoxic, biodegradable and biocompatible, and β-cyclodextrin can inhibit undesirable odors and improve the stability and bioavailability. Thus a promising dual-layer GEO β-cyclodextrin inclusion compound liposome (GEO-DCL) delivery system with both advantages was designed and prepared in this study. Experimental results indicated that the encapsulation efficiency of GEO-DCLs was 5% higher than that of GEO liposomes (GEO-CLs), reaching more than 88%...
March 7, 2024: Colloids and Surfaces. B, Biointerfaces