keyword
https://read.qxmd.com/read/38691770/ozone-chemistry-on-greasy-glass-surfaces-affects-the-levels-of-volatile-organic-compounds-in-indoor-environments
#1
JOURNAL ARTICLE
Huifan Deng, Jia Qiu, Runqi Zhang, Jinli Xu, Yuekun Qu, Jixuan Wang, Yingjun Liu, Sasho Gligorovski
The chemistry of ozone (O3 ) on indoor surfaces leads to secondary pollution, aggravating the air quality in indoor environments. Here, we assess the heterogeneous chemistry of gaseous O3 with glass plates after being 1 month in two different kitchens where Chinese and Western styles of cooking were applied, respectively. The uptake coefficients of O3 on the authentic glass plates were measured in the dark and under UV light irradiation typical for indoor environments (320 nm < λ < 400 nm) at different relative humidities...
May 1, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38691445/the-effect-of-total-knee-replacement-on-dual-task-gait-performance-in-older-adults
#2
JOURNAL ARTICLE
Ibrahim Azzam, Nimrod Rozen, Amir Eliyahu, Dan Dabby, Avi Elbaz, Amit Mor, Tal Krasovsky
OBJECTIVE: Total knee replacement (TKR) is a common solution for patients with advanced knee osteoarthritis. Still, fall rates remain relatively high after surgery. TKR may alter pain and knee function, balance control, and proprioception. However, given the role of complex (dual-task) walking in fall prediction for older adults, it is unknown how TKR alters the attentional demand of walking in older adults. The goal of this study was to examine the effect of TKR on dual-task walking among older adults...
May 1, 2024: Physical Therapy
https://read.qxmd.com/read/38690720/the-interplay-of-exercise-and-polyphenols-in-cancer-treatment-a-focus-on-oxidative-stress-and-antioxidant-mechanisms
#3
REVIEW
Yubing Wang
Exercise has been demonstrated to induce an elevated production of free radicals, leading to the onset of oxidative stress. Numerous studies highlight the positive impacts of aerobic exercise, primarily attributed to the increase in overall antioxidant capacity. The evidence suggests that engaging in aerobic exercise contributes to a reduction in the likelihood of advanced cancer and mortality. Oxidative stress occurs when there is an imbalance between the generation of free radicals and the collective antioxidant defense system, encompassing both enzymatic and nonenzymatic antioxidants...
May 1, 2024: Phytotherapy Research: PTR
https://read.qxmd.com/read/38690442/mortality-index-is-more-accurate-than-volume-in-predicting-outcome-and-failure-to-rescue-in-medicare-beneficiaries-undergoing-robotic-right-upper-lobectomy
#4
JOURNAL ARTICLE
J W Awori Hayanga, Elwin Tham, Manuel Gomez-Tschrnko, J Hunter Mehaffey, Jason Lamb, Paul Rothenberg, Vinay Badhwar, Alper Toker
BACKGROUND: Surgical volume is known to influence failure to rescue (FTR), defined as death following a complication. Robotic lung surgery continues to expand and there is variability in outcomes among hospitals. We sought to estimate the contribution of hospital-based factors on outcomes and FTR following robotic right upper lobectomy (RRUL). METHODS: Using the Centers for Medicare and Medicaid Services inpatient claims database, we evaluated all patients age ≥65 years with a diagnosis of lung cancer who underwent RRUL between January 2018 and December 2020...
April 2024: JTCVS open
https://read.qxmd.com/read/38690202/machine-learning-models-predict-the-emergence-of-depression-in-argentinean-college-students-during-periods-of-covid-19-quarantine
#5
JOURNAL ARTICLE
Lorena Cecilia López Steinmetz, Margarita Sison, Rustam Zhumagambetov, Juan Carlos Godoy, Stefan Haufe
INTRODUCTION: The COVID-19 pandemic has exacerbated mental health challenges, particularly depression among college students. Detecting at-risk students early is crucial but remains challenging, particularly in developing countries. Utilizing data-driven predictive models presents a viable solution to address this pressing need. AIMS: 1) To develop and compare machine learning (ML) models for predicting depression in Argentinean students during the pandemic. 2) To assess the performance of classification and regression models using appropriate metrics...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38690013/integration-of-the-butina-algorithm-and-ensemble-learning-strategies-for-the-advancement-of-a-pharmacophore-ligand-based-model-an-in-silico-investigation-of-apelin-agonists
#6
JOURNAL ARTICLE
Xuan-Truc Dinh Tran, Tieu-Long Phan, Van-Thinh To, Ngoc-Vi Nguyen Tran, Nhu-Ngoc Song Nguyen, Dong-Nghi Hoang Nguyen, Ngoc-Tam Nguyen Tran, Tuyen Ngoc Truong
Introduction: 3D pharmacophore models describe the ligand's chemical interactions in their bioactive conformation. They offer a simple but sophisticated approach to decipher the chemically encoded ligand information, making them a valuable tool in drug design. Methods: Our research summarized the key studies for applying 3D pharmacophore models in virtual screening for 6,944 compounds of APJ receptor agonists. Recent advances in clustering algorithms and ensemble methods have enabled classical pharmacophore modeling to evolve into more flexible and knowledge-driven techniques...
2024: Frontiers in Chemistry
https://read.qxmd.com/read/38689304/targeting-strategies-of-antenatal-balanced-energy-and-protein-supplementation-in-addis-ababa-ethiopia-study-protocol-for-a-randomized-effectiveness-study
#7
JOURNAL ARTICLE
Dongqing Wang, Tigest Shifraw, Janaina Calu Costa, Semira Abdelmenan, Sitota Tsegaye, Yoseph Berhane, Hanna Gulema, Hanna Berhane, Nebiyou Fasil, Firehiwot Workneh, Workagegnhu Tarekegn, Molin Wang, Nicolas A Menzies, Alemayehu Worku, Yemane Berhane, Wafaie W Fawzi
BACKGROUND: Antenatal balanced energy and protein (BEP) supplements have well-documented benefits for pregnancy outcomes. However, considerable practical gaps remain in the effective and cost-effective delivery of antenatal BEP supplements at scale in low- and middle-income countries. METHODS: A randomized effectiveness study will be conducted in two sub-cities of Addis Ababa, Ethiopia, to evaluate the effectiveness, cost-effectiveness, and implementation of different targeting strategies of antenatal BEP supplements...
April 30, 2024: Trials
https://read.qxmd.com/read/38689207/sorption-of-soil-carbon-dioxide-by-biochar-and-engineered-porous-carbons
#8
JOURNAL ARTICLE
Alexandra J Ringsby, Cynthia M Ross, Kate Maher
CO2 is 45 to 50 times more concentrated in soil than in air, resulting in global diffusive fluxes that outpace fossil fuel combustion by an order of magnitude. Despite the scale of soil CO2 emissions, soil-based climate change mitigation strategies are underdeveloped. Existing approaches, such as enhanced weathering and sustainable land management, show promise but continue to face deployment barriers. We introduce an alternative approach: the use of solid adsorbents to directly capture CO2 in soils. Biomass-derived adsorbents could exploit favorable soil CO2 adsorption thermodynamics while also sequestering solid carbon...
April 30, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38688550/reverse-total-shoulder-replacement-versus-anatomical-total-shoulder-replacement-for-osteoarthritis-population-based-cohort-study-using-data-from-the-national-joint-registry-and-hospital-episode-statistics-for-england
#9
COMPARATIVE STUDY
Epaminondas Markos Valsamis, Albert Prats-Uribe, Ian Koblbauer, Sophie Cole, Adrian Sayers, Michael R Whitehouse, Gillian Coward, Gary S Collins, Rafael Pinedo-Villanueva, Daniel Prieto-Alhambra, Jonathan L Rees
OBJECTIVES: To answer a national research priority by comparing the risk-benefit and costs associated with reverse total shoulder replacement (RTSR) and anatomical total shoulder replacement (TSR) in patients having elective primary shoulder replacement for osteoarthritis. DESIGN: Population based cohort study using data from the National Joint Registry and Hospital Episode Statistics for England. SETTING: Public hospitals and publicly funded procedures at private hospitals in England, 2012-20...
April 30, 2024: BMJ: British Medical Journal
https://read.qxmd.com/read/38688549/high-risk-ert-for-children-with-cardiac-critical-illness
#10
JOURNAL ARTICLE
Chen Yun Goh, Herng Lee Tan, Yi-Jyun Ma, Apollo Bugarin Aguilan, Wen Cong Lee, Anuradha P Menon, Yee Hui Mok, Judith Ju-Ming Wong
BACKGROUND: A protocolized extubation readiness test (ERT), including a spontaneous breathing trial (SBT), is recommended for patients who are intubated. This quality-improvement project aimed to improve peri-extubation outcomes by using a high-risk ERT protocol in intubated cardiac patients in addition to a standard-risk protocol. METHODS: After baseline data collection, we implemented a standard-risk ERT protocol (pressure support plus PEEP), followed by a high-risk ERT protocol (PEEP alone) in cardiac subjects who were intubated...
April 30, 2024: Respiratory Care
https://read.qxmd.com/read/38688507/triksv-lg-a-robust-approach-to-disease-prediction-in-healthcare-systems-using-ai-and-levy-gazelle-optimization
#11
JOURNAL ARTICLE
Kavitha Dhanushkodi, Prema Vinayagasundaram, Vidhya Anbalagan, Surendran Subbaraj, Ravikumar Sethuraman
A seamless connection between the Internet and people is provided by the Internet of Things (IoT). Furthermore, lives are enhanced using the integration of the cloud layer. In the healthcare domain, a reactive healthcare strategy is turned into a proactive one using predictive analysis. The challenges faced by existing techniques are inaccurate prediction and a time-consuming process. This paper introduces an Artificial Intelligence (AI) and IoT-based disease prediction method, the TriKernel Support Vector-based Levy Gazelle (TriKSV-LG) Algorithm, which aims to improve accuracy, and reduce the time of predicting diseases (kidney and heart) in healthcare systems...
April 30, 2024: Computer Methods in Biomechanics and Biomedical Engineering
https://read.qxmd.com/read/38688463/relationships-among-baseline-concussion-balance-test-and-gaze-stability-test-scores-in-division-i-collegiate-athletes
#12
JOURNAL ARTICLE
Carolina P Quintana, Anne D Olson, Nicholas R Heebner, Matthew C Hoch
CONTEXT: Sports-related concussions are commonly occurring injuries as a result of sports and recreation that may cause alterations in brain functioning. It is important to be able to evaluate the impact of these injuries on function to manage the injury recovery and ensure recovery. Recent literature suggests the use of objective evaluation strategies in a multifaceted approach to evaluate and manage these injuries. It is important to understand the relationships between the assessments and how best to utilize each assessment...
April 30, 2024: Journal of Sport Rehabilitation
https://read.qxmd.com/read/38688292/texture-preserving-low-dose-ct-image-denoising-using-pearson-divergence
#13
JOURNAL ARTICLE
Jieun Oh, Dufan Wu, Boohwi Hong, Dongheon Lee, Minwoong Kang, Quanzheng Li, Kyungsang Kim
The mean squared error (MSE), also known as $L_2$ loss, has been widely used as a loss function to optimize image denoising models due to its strong performance as a mean estimator of the Gaussian noise model. Recently, various low-dose computed tomography (LDCT) image denoising methods using deep learning combined with the MSE loss have been developed; however, this approach has been observed to suffer from the regression-to-the-mean problem, leading to over-smoothed edges and degradation of texture in the image...
April 30, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38687726/trend-change-analysis-in-the-assessment-of-body-balance-during-posture-adjustment-in-reaction-to-anterior-posterior-ground-perturbation
#14
JOURNAL ARTICLE
Piotr Wodarski, Marta Chmura, Michał Szlęzak, Grzegorz Bajor, Marek Gzik, Jacek Jurkojć
Postural adjustments (PA) occur to counteract predictable perturbations and can be impaired as a result of musculoskeletal and neurological dysfunctions. The most common way to detect PA is through electromyography measurements or center of pressure (COP) position measurements, where analysis in time domain and frequency domain are the most common. Aim of the research was to determine whether a new method of analyzing stabilographic measurements-the COP trend change analysis (TCI) of temporary posture corrections- can expand understanding of changes in balance strategy connected with PA...
2024: PloS One
https://read.qxmd.com/read/38686814/relationship-between-two-years-of-muscle-strength-decrease-and-volume-loss-of-menisci-and-cartilage-according-to-knee-pain-in-mild-and-moderate-knee-osteoarthritis
#15
JOURNAL ARTICLE
Hui Zhang, Tao Shuai, Junqing Wang Emd, Kang Li, Yong Nie
OBJECTIVE: To explore the relationship between two-year changes in muscle strength and cartilage according to knee pain in mild and moderate knee Osteoarthritis (OA). DESIGN: 279 participants were retrospectively obtained from the Osteoarthritis Initiative. Western Ontario McMaster University (WOMAC) and Knee Injury and Osteoarthritis Outcome Score were used to assess pain and function. Five muscles strength (maximum extensor and flexor, normalized maximum extensor and flexor, and extensor/flexor ratio) were measured from isometric strength test...
April 30, 2024: American Journal of Physical Medicine & Rehabilitation
https://read.qxmd.com/read/38686664/response-of-carbon-fixation-allocation-and-growth-to-source-sink-manipulation-by-defoliation-in-vegetative-citrus-trees
#16
JOURNAL ARTICLE
Sheng-Yang Li, Syed Bilal Hussain, Christopher Vincent
Source-sink balance in plants determines carbon distribution, and altering it can impact carbon fixation, transport, and allocation. We aimed to investigate the effect of altered source-sink ratios on carbon fixation, transport, and distribution in 'Valencia' sweet orange (Citrus x sinensis) by various defoliation treatments (0%, 33%, 66%, and 83% leaf removal). Gas exchange parameters were measured on 0 and 10 days after defoliation using A/Ci response curves, and leaf export was measured two days after defoliation using radioisotope tracer techniques...
2024: Physiologia Plantarum
https://read.qxmd.com/read/38686150/rapid-blueprinting-an-efficient-method-for-designing-content-of-assessments
#17
JOURNAL ARTICLE
Raja G Subhiyah, Amanda L Clauser, David F Martin
PROBLEM: Many assessments in medical education involve measuring proficiency in a content area. Thus, proper content development (blueprinting) of tests in this field is of primary importance. Prior efforts to conduct content review as part of assessment development have been time- and resource-intensive, relying on practice analysis and then on linking methods. This monograph explores a "rapid, cost-effective" approach to blueprinting that allows efficient assessment development with rigor...
April 2024: Medical Science Educator
https://read.qxmd.com/read/38686088/not-all-mindfulness-is-equal-certain-facets-of-mindfulness-have-important-implications-for-well-being-and-mental-health-across-the-lifespan
#18
JOURNAL ARTICLE
Nathaniel J Johnson, Ryan J Smith, Hali Kil
The connections between the five facets of mindfulness, well-being, and mental health across the lifespan have traditionally been investigated using variable-centered approaches. Less research has investigated these relationships from a person-centered, profile-based approach. In this work, we aimed to identify the profiles of mindfulness in a Canadian lifespan sample (14 to 90 years of age) and investigate how these profiles compared on age, well-being, and mental health. An age- and gender-balanced sample of 1,600 participants completed a questionnaire that measured the five facets of mindfulness; life satisfaction; existential well-being; and anxiety, depression, and stress symptoms...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38685927/efficacy-of-a-gamified-digital-therapy-for-speech-production-in-people-with-chronic-aphasia-italkbetter-behavioural-and-imaging-outcomes-of-a-phase-ii-item-randomised-clinical-trial
#19
JOURNAL ARTICLE
Emily Upton, Catherine Doogan, Victoria Fleming, Pedro Quijada Leyton, David Barbera, Peter Zeidman, Tom Hope, William Latham, Henry Coley-Fisher, Cathy Price, Jennifer Crinion, Alex Leff
BACKGROUND: Aphasia is among the most debilitating of symptoms affecting stroke survivors. Speech and language therapy (SLT) is effective, but many hours of practice are required to make clinically meaningful gains. One solution to this 'dosage' problem is to automate therapeutic approaches via self-supporting apps so people with aphasia (PWA) can amass practice as it suits them. However, response to therapy is variable and no clinical trial has yet identified the key brain regions required to engage with word-retrieval therapy...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38685874/apixaban-pharmacokinetics-and-bioequivalence-of-two-tablet-formulations-a-randomized-open-label-crossover-study-fasting-condition-in-healthy-indonesian-volunteers
#20
JOURNAL ARTICLE
Chuei Wuei Leong, Kar Ming Yee, Ivan Liew, Nur Athirah Khaleb, Shahnun Ahmad, Tracy Ann Rani, Kheng Jim Lau, Danang Agung Yunaidi, Ronal Simanjuntak, Vicky A Ginanjar
The present study aimed to assess the bioequivalence of a new apixaban generic with reference formulation. Twenty-six healthy volunteers were recruited for an open-label, balanced, randomized, 2-treatment, 2-sequence, 2-period, single oral dose study. Following overnight fasting, each volunteer received 5 mg of apixaban test and reference formulations as single doses, separated by a 1-week washout period. Twenty blood samples were collected at predose and multiple time points between 0.5 and 72 hours after dosing...
April 30, 2024: Clinical Pharmacology in Drug Development
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