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consensus conference

Jennifer An-Jou Lin, Angela Ting-Wei Hsu, Jung-Ju Huang, Bassem W Daniel, Che-Hsiung Lee, Soo-Ha Kwon, Evelyn Ting-Hsuan Tang, Cheng-Feng Chu, Cheng-An Tony Chien, David Chwei-Chin Chuang, Johnny Chuieng-Yi Lu, Isao Koshima, Zeng-Tao Wang, Liwen Hao, Chao Chen, Tommy Nai-Jen Chang
BACKGROUND:  Medical conferences are forums for research, continuing medical education, and networking. Social media is increasingly used for communication and networking due to its low cost and ability to overcome large distances. This study investigates the impact that social media brings to the current conference system. METHODS:  There are three parts of this study: (1) comparing two similar brachial plexus injuries (BPIs) courses without (2009) and with (2017) social media support, and the participants' feedback; (2) sharing our experiences in the management of the 2018 International Course on SuperMicrosurgery (ICSM) conference; and (3) evaluating the studies from the social media platform International Microsurgery Club (IMC), for the consensus pertaining to social media and conference system...
February 13, 2019: Journal of Reconstructive Microsurgery
Ilse S Peterson, William O Iverson, Marion T Kasaian, Maggie Liu
Progressive multifocal leukoencephalopathy (PML) is a rare but serious disease. Caused by the JC virus (JCV), it occurs in individuals with weakened immune systems and is a potential adverse reaction for certain immunomodulatory drugs. The PML Consortium was created to find better methods to predict, prevent, and treat PML. The Consortium brought together the pharmaceutical industry with academic, regulatory, and patient communities to advance research and dialogue on PML through a not-for-profit, collaborative approach involving a grant program, scientific workshops and conferences, and disease awareness efforts...
February 13, 2019: Advances in Therapy
Tut Galai, Shlomi Cohen, Anat Yerushalmy-Feler, Yael Weintraub, Hadar Moran-Lev, Achiya Z Amir
OBJECTIVES: The course and evolution of pediatric acute pancreatitis (AP) is poorly understood. Prognostication models in children perform poorly and lack consensus. We aimed to identify predictors of AP severity, and the risk for AP recurrence. METHODS: We retrospectively studied all patients hospitalized with AP at a single tertiary center, between January 1995 and June 2016. Patient demographics and admission laboratory data were assessed for severity and recurrence prediction...
February 7, 2019: Journal of Pediatric Gastroenterology and Nutrition
Andrew W Perez, Jennifer M Watchmaker, Daniel B Brown, Filip Banovac
Background Patients who require long-term central venous access can present for port placement with depressed immune function as a result of their treatment or disease process. At present, there is no consensus regarding whether neutropenia at the time of port placement confers a higher risk for early infection-related port removal. Purpose To compare the incidence of early infection-related chest port removal in adults when placed in neutropenic versus nonneutropenic patient groups. Materials and Methods This retrospective cohort study examined 2580 port placements in 1081 men (41...
February 12, 2019: Radiology
Leonardo Emberti Gialloreti, Luigi Mazzone, Arianna Benvenuto, Alessio Fasano, Alicia Garcia Alcon, Aletta Kraneveld, Romina Moavero, Raanan Raz, Maria Pia Riccio, Martina Siracusano, Ditza A Zachor, Marina Marini, Paolo Curatolo
Autism Spectrum Disorder (ASD) is a complex condition with early childhood onset, characterized by a set of common behavioral features. The etiology of ASD is not yet fully understood; however, it reflects the interaction between genetics and environment. While genetics is now a well-established risk factor, several data support a contribution of the environment as well. This paper summarizes the conclusions of a consensus conference focused on the potential pathogenetic role of environmental factors and on their interactions with genetics...
February 8, 2019: Journal of Clinical Medicine
Shuangwei Song, Liaoyang Hao, Pan Zhao, Ya Xu, Naiqin Zhong, Hongji Zhang, Ning Liu
Auxin response factors (ARFs) play central roles in conferring auxin-mediated responses through selection of target genes in plants. Despite their physiological importance, systematic analysis of ARF genes in potato have not been investigated yet. Our genome-wide analysis identified 20 StARF (Solanum tuberosum ARF) genes from potato and found that they are unevenly distributed in all the potato chromosomes except chromosome X. Sequence alignment and conserved motif analysis suggested the presence of all typical domains in all but StARF18c that lacks B3 DNA-binding domain...
February 11, 2019: Scientific Reports
Francis Lovecchio, Jeffrey G Stepan, Ajay Premkumar, Michael E Steinhaus, Maria Sava, Peter Derman, Han Jo Kim, Todd Albert
OBJECTIVEPatients with lumbar spine pathology are at high risk for opioid misuse. Standardizing prescribing practices through an institutional intervention may reduce the overprescribing of opiates, leading to a decrease in the risk for opioid misuse and the number of pills available for diversion. Without quantitative data on the "minimum necessary quantity" of opioids appropriate for postdischarge prescriptions, the optimal method for changing existing prescribing practices is unknown. The purpose of this study was to determine whether mandatory provider education and prescribing guidelines could modify prescriber behavior and lead to a decreased amount of opioids prescribed at hospital discharge following lumbar spine surgery...
February 5, 2019: Journal of Neurosurgery. Spine
Jorge Sapunar, Alex Escalona, A Verónica Araya, Carmen Gloria Aylwin, María Juliana Bastías, Camilo Boza, Carlos Cárcamo, Attila Csendes A, Patricio Davidof F, Ricardo Funke, Patricia Gómez, María Isabel González, Rodolfo Lahsen, Enrique Lanzarini, Alberto Maíz, Verónica Mujica, Rodrigo Muñoz, Gustavo Pérez, Félix Raimann, Patricio Salman, Matías Sepúlveda, Néstor Soto, Rodrigo Villagrán
Diabetes Mellitus (DM) and obesity are a public health problem in Chile. Bariatric surgery is the most effective treatment alternative to achieve a significant and sustained weight reduction in patients with morbid obesity. The results of controlled clinical trials indicate that, compared to medical treatment, surgery for obese patients with DM2 allows a better control of blood glucose and cardiovascular risk factors, reduces the need for medications and increases the likelihood for remission. Consensus conferences and clinical practice guidelines support bariatric surgery as an option to treat DM2 in Class III Obesity (Body Mass Index (BMI) > 40) regardless of the glycemic control and the complexity of pharmacological treatment and in Class II Obesity (BMI 35-39,9) with inadequate glycemic control despite optimal pharmacological treatment and lifestyle...
December 2018: Revista Médica de Chile
Marcos Chena, María Luisa Rodríguez, Antonio J Bores, Domingo J Ramos-Campo
BACKGROUND: The high injury rate in football has highlighted the need to research strategies that allow the modification of the dynamic risk factors. Most of the preventive proposals have focused on standardized protocols. However, the aim of this study was to evaluate the effect of a multifactorial injuries prevention program (MC-7) in Spanish football players. METHODS: A total of 219 Spanish football male players aged 16-23 were studied. The study was conducted over two consecutive seasons (2012-2013, 2013-2014)...
February 5, 2019: Journal of Sports Medicine and Physical Fitness
C Orssaud, S Bidot, C Lamirel, D Brémond Gignac, V Touitou, C Vignal
INTRODUCTION: Leber's Hereditary Optic Neuropathy (LHON) causes a rapid and severe decrease in visual acuity. Raxone® (Idebenone, Santhera) is the only drug to have a European Marketing Authorization for the treatment of this optic neuropathy. It can be proposed in the first months after the onset of this optic neuropathy, according to an international consensus meeting. PATIENTS AND METHODS: Retrospective study of the efficacy of Raxone® on the visual acuity of patients with genetically confirmed LHON who were followed in four Parisian hospitals...
January 31, 2019: Journal Français D'ophtalmologie
Carina Jensen, Jesper Carl, Lars Boesen, Niels Christian Langkilde, Lasse Riis Østergaard
PURPOSE: To automatically assess the aggressiveness of prostate cancer (PCa) lesions using zonal-specific image features extracted from diffusion weighted imaging (DWI) and T2W MRI. METHODS: Region of interest was extracted from DWI (peripheral zone) and T2W MRI (transitional zone and anterior fibromuscular stroma) around the center of 112 PCa lesions from 99 patients. Image histogram and texture features, 38 in total, were used together with a k-nearest neighbor classifier to classify lesions into their respective prognostic Grade Group (GG) (proposed by the International Society of Urological Pathology 2014 consensus conference)...
February 3, 2019: Journal of Applied Clinical Medical Physics
Pascal Djiadeu, Joseph Nguemo, Chantal Mukandoli, Apondi J Odhiambo, David Lightfoot, Lawrence Mbuagbaw, LaRon E Nelson
INTRODUCTION: Language is a social determinant of health. Addressing social determinants of health is paramount to successful progression along the HIV-care continuum. Canada is a bilingual country with French and English as official languages. There are few studies to date that have focused on the impact of being a French-speaking linguistic minority on the HIV-care continuum. The primary objective of this scoping, systematic review of literature is to evaluate existing gaps in access to HIV- care among French-speaking people living with HIV in Canada...
January 30, 2019: BMJ Open
E M Shchegoleva, N M Bulanov, P I Novikov, S V Moiseev
AIM: To evaluate clinical features and outcomes of renal involvement in patients with microscopic polyangiitis (MPA). MATERIALS AND METHODS: We enrolled 99 patients with MPA, diagnosed in accordance with the algorithm of the European Medicines Evaluation Agency (EMEA) and the Chapel Hill consensus conference definition (2012). Serum creatinine (sCr), estimated glomerular filtration rate (eGFR), hematuria and proteinuria were estimated. Frequency of rapidly progressive renal failure (a twofold increase in the sCr level in ≤3 months) was regarded as the clinical equivalent of rapidly progressive glomerulonephritis (RPGN)...
June 20, 2018: Terapevticheskiĭ Arkhiv
N M Bulanov, E A Makarov, E M Shchegoleva, A S Zykova, E S Vinogradova, P I Novikov, L V Lysenko Kozlovskaya, S V Moiseev
AIM: To compare the frequency, clinical features and outcomes of renal involvement in ANCA-associated vasculitides (AAV) in patients with antibodies against proteinase-3 (pr3-ANCA) and myeloperoxidase (MPO-ANCA). MATERIALS AND METHODS: In our retrospective study we enrolled 264 patients, 94 males and 170 females, median age 53 [36; 62] years. Among them 157 were pr3-ANCA positive and 107 were MPO-ANCA positive. AAV was diagnosed according to ACR criteria and Chapel Hill consensus conference definition (2012)...
June 20, 2018: Terapevticheskiĭ Arkhiv
H X Meng
World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions was held in Chicago on November 9 to 11, 2017. More than one hundred experts from all over the world attended the conference and updated the 1999 classification of periodontal diseases and conditions, and developed a similar scheme for peri-implant diseases and conditions. The case definitions and diagnostic criteria were also established to aid clinicians in the use of the new classification. Nineteen review papers and four consensus reports covering relevant areas in periodontology and implant dentistry were simultaneously published in special issue of Journal of Periodontology and Journal of Clinical Periodontology in June 2018...
February 9, 2019: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
Lars Egevad, Brett Delahunt, John Yaxley, Hemamali Samaratunga
Histological grading of prostate cancer is one of the most important tissue-based parameters for prediction of outcome and treatment response. Gleason grading remains the foundation of prostate cancer grading, but has undergone a series of changes in the past 30 years, often initiated by consensus conference decisions. This review summarizes the most important modifications that were introduced by the 2005 and 2014 International Society of Urological Pathology (ISUP) revisions of Gleason grading and discusses the impact that these have had on current grading practices...
January 29, 2019: Pathology International
Maureen P McEvoy, Jeffrey Landercasper, Himani R Naik, Sheldon Feldman
In 2015, the American Society of Breast Surgeons (ASBrS) convened a multidisciplinary consensus conference, the Collaborative Attempt to Lower Lumpectomy Reoperation Rates (CALLER). The CALLER conference endorsed a "toolbox" of multiple processes of care for which there was evidence that they were associated with fewer reoperations. We present an update of the toolbox taking into consideration the latest advances in decreasing re excision rates. In this review, we performed a comprehensive review of the literature from 2015-2018 using search terms for each tool...
December 2018: Gland Surgery
K Ostrowsky-Coste, A Neal, M Guenot, P Ryvlin, S Bouvard, P Bourdillon, J Jung, H Catenoix, A Montavont, J Isnard, A Arzimanoglou, S Rheims
Medically treated patients suffering from tuberous sclerosis complex (TSC) have less than 30% chance of achieving a sustained remission. Both the international TSC consensus conference in 2012, and the panel of European experts in 2012 and 2018 have concluded that surgery should be considered for medically refractory TSC patients. However, surgery remains currently underutilized in TSC. Case series, meta-analyses and guidelines all agree that a 50 to 60% chance of long-term seizure freedom can be achieved after surgery in TSC patients and a presurgical work-up should be done as early as possible after failure of two appropriate AEDs...
January 24, 2019: Revue Neurologique
Joan Kaufman, Souraya Torbey
This paper reviews the literature on the association between experiences of child abuse and neglect and the development of psychoses. It then explores the premise that psychotic patients with a history of maltreatment may comprise a clinically and biological distinct subgroup. The review demonstrates that there is a growing consensus in the field that experiences of child maltreatment contribute to the onset of psychotic symptoms and psychotic disorders. There is also strong support for the premise that patients with psychotic disorders and histories of child maltreatment have distinct clinical characteristics and unique treatment needs, and emerging preliminary data to suggest psychotic patients with a history of maltreatment may comprise a distinct neurobiological subgroup...
January 24, 2019: Neurobiology of Disease
Hermine I Brunner, Michael J Holland, Michael W Beresford, Stacy P Ardoin, Simone Appenzeller, Clovis A Silva, Francisco Flores, Beatrice Goilav, Pinar Ozge Avar Aydin, Scott E Wenderfer, Deborah M Levy, Angelo Ravelli, Raju Khubchandani, Tadej Avcin, Marisa S Klein-Gitelman, Nicolino Ruperto, Brian M Feldman, Jun Ying
OBJECTIVES: To develop a Childhood Lupus Improvement Index (CHILI) as a tool to measure response to therapy in childhood-onset systemic lupus erythematosus (cSLE), with focus on clinically relevant improvement (CRIc SLE ). METHODS: Pediatric nephrology and rheumatology subspecialists (n=213) experienced in cSLE management were invited to define CRIc SLE and rate a total of 433 unique patient-profiles for the presence/absence of CRIc SLE . Patient-profiles included the cSLE core response variables [cSLE-CRVs: global assessment of patient well-being (Patient-global), physician assessment of cSLE activity (MD-global), disease activity index score (here: Systemic Lupus Erythematosus Disease Activity Index), urine protein-to-creatinine ratio (UPCR), Child Health Questionnaire physical summary score (CHQ-PhS)]...
January 25, 2019: Arthritis Care & Research
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