Evdokia Gavrielatou, Katerina Vaporidi, Vasiliki Tsolaki, Nikos Tserlikakis, George E Zakynthinos, Eleni Papoutsi, Aikaterini Maragkuti, Athina G Mantelou, Dimitrios Karayiannis, Zafeiria Mastora, Dimitris Georgopoulos, Epaminondas Zakynthinos, Christina Routsi, Spyros G Zakynthinos, Edward J Schenck, Anastasia Kotanidou, Ilias I Siempos
BACKGROUND: Before the pandemic of coronavirus disease (COVID-19), rapidly improving acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been recognized as an increasingly prevalent subphenotype (making up 15-24% of all ARDS cases), associated with good prognosis (10% mortality in ARDSNet trials). We attempted to determine the prevalence and prognosis of rapidly improving ARDS and of persistent severe ARDS related to COVID-19. METHODS: We included consecutive patients with COVID-19 receiving invasive mechanical ventilation in three intensive care units (ICU) during the second pandemic wave in Greece...
April 14, 2022: Respiratory Research