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Seye Abimbola
Showing the causal link between community engagement and improved health outcomes is a 'holy grail' of health policy. This article argues that this 'holy grail' has remained elusive because community engagement in primary health care is under-theorized, having been based on positive a priori assumptions, e.g. that people necessarily want to be engaged in governing their health system. By adopting a theory-driven approach and an agnostic premise, we show that understanding why, how and when community engagement may emerge or function spontaneously is important for informing efforts to support community engagement in primary health care primary health care governance...
April 14, 2019: Health Promotion International
Mohammad Ghorbani, Christoph Wipplinger, Christoph J Griessenauer, Seyed Ebrahim Hejazian, Fatemeh Zangi Abadi, Sina Asaadi
Pial arteriovenous fistulas (pAVFs) are abnormal vascular connections between arteries and the cranial venous system on the surface of the brain in the pia mater. Unlike vein of Galen aneurysmal malformations (VGAM), they lack a true vascular nidus, and may only indirectly involve the vein of Galen. We describe a case of a pAVF with a presentation resembling a VGAM and discuss the importance of considering a pAVF as a possible differential diagnosis to a VGAM when the vein of Galen is dilated.
April 11, 2019: World Neurosurgery
Fereshteh Rezazadeh, Navid Taheri, Seyed Mehdi Okhravi, Sayed Mohsen Hosseini
BACKGROUND: Nonspecific low back pain (NSLBP) is a common problem that may have an effect on the level of functional ability. Imaging techniques indicated the degeneration of multifidus muscles in patients with low back pain. But its relationship with disability in NSLBP is unclear. OBJECTIVE: To assess the relationship between changes in multifidus muscle morphology in MRI as paraclinical data with changes in the level of disability as clinical data in patients with CNLBP, whose MRI studies are normal...
March 21, 2019: Musculoskeletal Science & Practice
Fatemeh Vahdat Lasemi, Maryam Mahjoubin Tehran, Seyed Hamid Aghaee-Bakhtiari, Amin Jalili, Mahmoud Reza Jaafari, Amirhossein Sahebkar
Dyslipidemia is one of the major but modifiable risk factors for atherosclerotic cardiovascular disease (ACVD). Despite the accessibility of statins and other lipid-lowering drugs, the burden of ACVD is still high globally, highlighting the need for new therapeutic approaches. Nucleic acid-based technologies, including antisense oligonucleotides (ASOs), small interfering (si)RNAs, miRNAs, and decoys, are emerging therapeutic modalities for the treatment of ACVD. These technologies aim to degrade gene mRNA transcripts to decrease the levels of atherogenic lipoproteins...
April 10, 2019: Drug Discovery Today
Valentin R Troll, Franz A Weis, Erik Jonsson, Ulf B Andersson, Seyed Afshin Majidi, Karin Högdahl, Chris Harris, Marc-Alban Millet, Sakthi Saravanan Chinnasamy, Ellen Kooijman, Katarina P Nilsson
Kiruna-type apatite-iron-oxide ores are key iron sources for modern industry, yet their origin remains controversial. Diverse ore-forming processes have been discussed, comprising low-temperature hydrothermal processes versus a high-temperature origin from magma or magmatic fluids. We present an extensive set of new and combined iron and oxygen isotope data from magnetite of Kiruna-type ores from Sweden, Chile and Iran, and compare them with new global reference data from layered intrusions, active volcanic provinces, and established low-temperature and hydrothermal iron ores...
April 12, 2019: Nature Communications
Seyed Abolfazl Valizadeh, Robert Riener, Stefan Elmer, Lutz Jäncke
Biometric identification (BI) of individuals is a fast-growing field of research that is producing increasingly sophisticated applications in several spheres of everyday life. Previous magnetic resonance imaging (MRI) studies have demonstrated that based on the high inter-individual variability of brain structure and function, it is possible to identify individuals with high accuracy. Otherwise, there is the common belief that electroencephalographic (EEG) data recorded at the surface of the scalp are too noisy for identification purposes with a comparably high hit rate...
April 9, 2019: NeuroImage
Marjan Khazan, Soheila Nasiri, Seyed Mohammad Riahi, Reza M Robati, Mehdi Hedayati
The risk of herpes zoster (HZ) increases with age and declining immune function. Increased oxidative stress and inflammatory conditions may cause negative impact on the immune responses. The present study aimed to assess the levels of oxidative/inflammatory stress biomarkers in HZ patients compared with the controls. This case-control study included 43 HZ patients and 47 age-matched controls. Melatonin (MLT), Indole-dioxygenase (IDO), Interleukin-18 (IL-18), Interleukin-6 (IL-6), ferritin, C-reactive protein (hsCRP), and total homocysteine (tHcy) levels were measured and compared in both groups...
April 12, 2019: Journal of Medical Virology
Seth A Climans, Seyed M Mirsattari
Hemimegalencephaly is a malformation of cortical development that normally manifests in childhood with seizures and cognitive impairment. We present a case of hemimegalencephaly in a 55-year-old developmentally-normal woman who developed focal impaired awareness seizures with bilateral tonic-clonic spread. Her interictal EEG showed left-sided multifocal spikes, and ictal EEG showed seizures starting in the left hemisphere. Imaging showed hemimegalencephaly. This case may represent the oldest age for a first seizure in a patient with hemimegalencephaly...
April 12, 2019: Epileptic Disorders: International Epilepsy Journal with Videotape
Farzad Bozorgi, Iraj Goli Khatir, Hesam Ghanbari, Fatemeh Jahanian, Mohsen Arabi, Hamed Amini Ahidashti, Seyed Mohammad Hosseininejad, Mir Saeid Ramezani, Seyed Hossein Montazer
BACKGROUND: Death in multiple trauma (MT) patients is one of the serious concerns of the medical service provider. Any prediction of the likelihood of death on the assessment of the patient's condition is performed using different variables, one of the tools in the triage of patients to determine their condition. AIM: We aimed to investigate the frequency and the predictive value of death in 24 hours triad of death in patients qualified with multiple traumas admitted to Imam Khomeini hospital...
March 30, 2019: Open Access Macedonian Journal of Medical Sciences
Farideh Tabatabaee Yazdi, Fereshteh Falah, Alireza Vasiee, Behrooz Alizadeh Behbahani, Samira Moradi, Seyed Ali Mortazavi, Sahar Roshanak
Gastrointestinal (GI) infection is one of the most common types of infectious diseases. Application of probiotic strains in the control of such infections represents a promising approach. In this study, Lactobacillus fermentum strain 4-17 was isolated from kashkineh, an Iranian cereal fermented food, and identified by sequencing its 16S rRNA gene using universal primers. Its probiotic features, including resistance to acid, bile tolerance, antibacterial activity, resistance to intestinal and gastric juices, and hydrophobicity were evaluated...
April 8, 2019: Microbial Pathogenesis
Hamid Reza Baghani, Seyed Rashid Hosseini Aghdam, Mostafa Robatjazi, Seyed Rabi Mahdavi
Evaluating the stray radiation around medical electron accelerators is a mandatory issue. Surveying the radiation leakage dose is important for patients, technicians, and health physicists, due to radiation protection aspects. Consequently, radiation leakage dose around the head of a mobile-dedicated intraoperative radiotherapy accelerator (LIAC), at different electron energies and field sizes have been evaluated in this study. More specifically, the MCNPX Monte Carlo code was used to model the LIAC head, connected applicator, and employed water phantom...
April 10, 2019: Radiation and Environmental Biophysics
Ali Mohammad Haji Zeinali, Yaser Jenab, Hamid Ariannejad, Seyed Ebrahim Kassaian, Mohammad Alidoosti, Hassan Aghajani, Mohammad Reza Zafarghandi
Iliofemoral deep vein thrombosis (IFDVT) is a potentially devastating condition comprising a quarter of all cases of lower extremity DVT. It can lead to serious consequences such as pulmonary embolism, limb malperfusion, and post-thrombotic syndrome (PTS), which is a chronic sequela of IFDVT. We herewith present 18 IFDVT cases managed with catheter-directed thrombolysis at our hospital. Nine of these patients underwent stenting of the involved iliac veins. The remaining 9, who did not receive stenting, had a residual stenosis of more than 50% in the common femoral or iliac veins following the procedure...
October 2018: Journal of Tehran Heart Center
Abbasali Karimi, Seyed Hesameddin Abbasi
No abstract text is available yet for this article.
October 2018: Journal of Tehran Heart Center
Shih-Luen Wang, Seyed M M Kahaki, Armen Stepanyants
The ability to extract accurate morphology of labeled neurons from microscopy images is crucial for mapping brain connectivity and for understanding changes in connectivity that underlie learning and neurological disorders. There are, however, two problems, specific to optical microscopy imaging of neurons, which make accurate neuron tracing exceedingly challenging: ( i ) neurites can appear broken due to inhomogeneous labeling and ( ii ) neurites can appear fused in 3D due to limited resolution. Here, we propose and evaluate several artificial neural network (ANN) architectures and conventional image enhancement filters with the aim of alleviating both problems...
February 2019: Proceedings of SPIE
Raheleh Hashemi Habybabady, Mahdi Mohammadi, Seyed Bagher Mortazavi, Ali Khavanin, Ramazan Mirzaei, Mehdi Sadeghi Malvajerdi
Cigarette smoking is a possible risk factor for hearing loss. However, the impact of simultaneous exposure to noise and smoke on hearing has remained controversial. This study investigated the combined effect of exposure to cigarette smoking and noise on hearing loss. Three groups of male Wistar rats (275 ± 25 g) were subjected to white noise (102 ± 0.5 dB), cigarette smoking (20 cigarettes), and both cigarette smoking and noise for 8 h and 10 days inside the exposure chamber. The control group was exposed to neither noise nor smoke...
April 10, 2019: Toxicology and Industrial Health
Arash Mohammadinejad, Seyed Mohammad Taghdisi, Zarrin Es'haghi, Khalil Abnous, Seyed Ahmad Mohajeri
Breast cancer which is the most commonly diagnosed cancer among women; have been known as a serious threat for health and life around the world. So development of an approach for early-stage diagnosis of breast cancer is vital. In this study, we designed a double aptamer-nanoparticle conjugates-based (DANP) complex for specific detection and visualization of MCF-7 cells using Mucin 1 (MUC 1) aptamer-conjugated gold nanoparticles (MUC1 apt - GNPs) and adenosine triphosphate (ATP) aptamer-conjugated CdTe quantum dots (ATP apt-QDs)...
April 7, 2019: European Journal of Pharmaceutical Sciences
Majid Seyed Salehi, Nozar Anjabin, Hyoung S Kim
During recrystallization, the growth of fresh grains initiated within a deformed microstructure causes dramatic changes in the dislocation structure and density of a heavily deformed matrix. In this paper, the microstructure of a cold rolled and partially recrystallized Al-Mg alloy (AA5052) was studied via electron backscattered diffraction (EBSD) analysis. The structure and density of the geometrically necessary dislocations (GNDs) were predicted using a combination of continuum mechanics and dislocation theory...
April 10, 2019: Microscopy and Microanalysis
Mohabbat Ghaempoor, Ehsan Arefian, Seyed R Mohebbi, Mehrnoosh Shanaki, Faranak Kazerouni, Behzad Hatami
BACKGROUND: Sensitive and specific diagnostic indicators are essential for liver cirrhosis. This study aims to analyze two plasma microRNAs (miR-625 and miR-920) as possible biomarkers for liver cirrhosis. METHODS: miR-625 and miR-920 expressions were analyzed in the plasma of 40 patients with liver cirrhosis and 41 healthy controls. Plasma levels of miR-625 and miR-920 were assessed by qRT-PCR. Analysis of the results was performed by the Mann-Whitney U-test. Spearman's test was used to show correlations between the miR-625 and clinical parameters...
April 1, 2019: Clinical Laboratory
Pedram G Renani, Forogh Taheri, Daryoush Rostami, Najmeh Farahani, Hamed Abdolkarimi, Elahe Abdollahi, Eskandar Taghizadeh, Seyed Mohammad Gheibi Hayat
Parkinson's disease (PD) is known as a progressive neurodegenerative disorder associated with the reduction of dopamine-secreting neurons and the formation of Lewy bodies in the substantia nigra and basal ganglia routes. Aging, as well as environmental and genetic factors, are considered as disease risk factors that can make PD as a complex one. Epigenetics means studying heritable changes in gene expression or function, without altering the underlying DNA sequence. Multiple studies have shown the association of epigenetic variations with onset or progression of various types of diseases...
April 9, 2019: Journal of Cellular Physiology
Anita Ebrahimpour, Seyed Salman Zakariaee, Marjaneh Hejazi
Background: Molecular fluorescence imaging is widely used as a noninvasive method to study the cellular and molecular mechanisms. In the optical imaging system, the sensitivity is the change of the intensity received by the detector for the changed optical characteristics (fluorescence) in each sample point. Sensitivity could be considered as a function of imaging geometry. A favor imaging system has a uniform and high-sensitivity coefficient for each point of the sample. In this study, a new parameter was proposed which the optimal angle between the source and detector could be determined based on this parameter...
January 2019: Journal of Medical Signals and Sensors
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