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JOURNAL ARTICLE
Yu Liang, Yongjin Xiang, Zhiyuan Wei, Marcelo Avena, Juan Xiong, Jingtao Hou, Mingxia Wang, Wenfeng Tan
Hematite nanoparticles commonly undergoes isomorphic substitution of Al3+ in nature, while how the Al-substitution-induced morphological change, defective structure and newly generated Al-OH sites affect the adsorption behavior of hematite for contaminants remains poorly understood. Herein, the interfacial reactions between Al-substituted hematite and Pb2+ was investigated via CD-MUSIC modeling and DFT calculations. As the Al content increased from 0% to 9.4%, Al-substitution promoted the proportion of (001) facets and caused Fe vacancies on hematite, which increased the total active site density of hematite from 5...
April 13, 2024: Environmental Research
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JOURNAL ARTICLE
Xun Li, Minghe Yao, Lingling Li, Huifen Ma, Yiran Sun, Xiangpeng Lu, Weipeng Jing, Shanshan Nie
BACKGROUND: Microglial activation plays a crucial role in injury and repair after cerebral ischemia, and microglial pyroptosis exacerbates ischemic injury. NOD-like receptor protein 3 (NLRP3) inflammasome activation has an important role in microglial polarization and pyroptosis. Aloe-emodin (AE) is a natural anthraquinone compound originated from rhubarb and aloe. It exerts antioxidative and anti-apoptotic effects during cerebral ischemia/reperfusion (I/R) injury. However, whether AE affects microglial polarization, pyroptosis, and NLRP3 inflammasome activation remains unknown...
April 7, 2024: Phytomedicine
#23
JOURNAL ARTICLE
Thant Aye Aye, Sangvanich Polkit, Inchudech Klaijan, Kuvieng Nachanok, Lalitkanjanakul Salil, Thunyakitpisal Pasutha
BACKGROUND/PURPOSE: Resin-modified glass ionomers (RMGIs) have been recommended as liner and cement to provide the teeth with mechanical support, a chemical barrier, and thermal insulation. Acemannan, the main polysaccharide extracted from Aloe vera, is a promising inductive material in vitro and in vivo . This study aimed to develop acemannan-containing bioactive resin-modified glass ionomers (RMGIs). MATERIALS AND METHODS: Acemannan (3%, 5%, and 10%) was added to the three types of RMGIs (RU-HBM1/Fuji II LC/Vitrebond) to generate 3%, 5%, and 10% aceRMGIs (aceRU/aceFuji/aceVB)...
April 2024: Journal of Dental Sciences
#24
JOURNAL ARTICLE
E Villegas-Becerril, C Jimenez-Garcia, L A Perula-de Torres, M Espinosa-Calvo, C M Bueno-Serrano, F Romero-Ruperto, F Gines-Santiago, M C Moreno-Manzanaro, J J Muñoz-Gavilan, G Montes-Redondo, M A Quesada-Roman, M C Linares-Ramirez, J M Parras-Rejano, N Muñoz-Alcaraz, M D Maestre-Serrano, E M Romero-Rodriguez
OBJECTIVES: Radiation-induced dermatitis (RD) is one of the most common toxicities in radiation therapy (RT) patients. Corticosteroids, immunosuppressants, and natural products (NPs) have been used as treatment. The objective was to evaluate the efficacy of a NPs-based cream (Alantel®) to reduce the incidence of RD in women with breast cancer undergoing RT treatment. DESIGN: We conducted a controlled, randomized, double-blind clinical trial. SETTING: Radiation Oncology Unit of the Reina Sofía Hospital and 5 Primary Care centers of the Cordoba and Guadalquivir Health District (Spain)...
June 2024: Contemporary Clinical Trials Communications
#25
JOURNAL ARTICLE
Suijun Xiao, Yufei Lao, Hongbo Liu, Dacheng Li, Qiaoyan Wei, Liangdong Ye, Shaorong Lu
Developing high-performance hydrogels with anti-freeze, and antimicrobial properties is crucial for the practical application of flexible sensors. In this study, we prepared silver nanoparticles (AgNPs) with aloe polysaccharide (AP) as a reducing agent. Then, the AP/AgNPs were added to a system of polyvinyl alcohol and borax crosslinked in water/glycerol to obtain a multifunctional conductive hydrogel. The incorporated AgNPs improved the conductivity (0.39 S/m) and mechanical properties (elongation at break: 732...
April 11, 2024: International Journal of Biological Macromolecules
#26
JOURNAL ARTICLE
Fabio Alves Teixeira, Vivian Pedrinelli, Mariana Yukari Hayasaki Porsani, Brana Sanctos Alo Bonder, Ana Beatriz Fasolai, Marcio Antonio Brunetto
Obesity is a highly prevalent disease in dogs and is characterized by the excessive accumulation of adipose tissue that results in metabolic changes. Its treatment is based on a negative energy balance focusing on energy restriction. However, there are few studies in dogs that assessed the energy intake needed for adequate weight loss and to weight maintenance afterward. The aim of this study was to evaluate data about the treatment of canine obesity, with emphasis on energy restriction to induce weight loss and to maintain body weight (BW) and ideal body condition after weight loss...
April 13, 2024: Journal of Animal Physiology and Animal Nutrition
#27
JOURNAL ARTICLE
Viktor Filatov, Anna Sokolova, Natalya Savitskaya, Mariya Olkhovskaya, Andrey Varava, Egor Ilin, Elizaveta Patronova
Aquaporin 3 (AQP3) channels are tetrameric membrane-bound channels that facilitate the transport of water and other small solutes across cell membranes in the skin. Decreased AQP3 expression is associated with skin dryness, skin aging, psoriasis, and delayed wound healing. Thus, our study focused on a novel combination based on Aloe barbadensis leaf extract and trimethylglycine for targeted AQP3 regulation in skin keratinocytes and deep skin moisturization. Firstly, a dose-finding cytotoxicity assay of the selected substances was performed with a 2,5-diphenyl-2H-tetrazolium bromide (MTT) indicator on HaCaT cells...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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JOURNAL ARTICLE
Bolesław Szadkowski, Magdalena Śliwka-Kaszyńska, Anna Marzec
Functional antibacterial textile materials are in great demand in the medical sector. In this paper, we propose a facile, eco-friendly approach to the design of antibacterial biodegradable cotton fabrics. Cotton fiber fabrics were enhanced with a chitosan coating loaded with plant extracts and essential oils. We employed Fourier-transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS), UV-Vis spectrophotometry, optical microscopy, scanning electron microscopy (SEM), and thermogravimetric analysis (TGA) to characterize the color, structure, and thermal properties of the modified fabrics...
April 12, 2024: Scientific Reports
#29
JOURNAL ARTICLE
Xiao-Na Dong, Meng-Ting Li
OBJECTIVE: Aloperine (ALO) is an effective quinolizidine alkaloid. Previous research has demonstrated its antiarrhythmic effect by inhibiting voltage-gated sodium currents in rat ventricular myocytes. This study explored its effect on transient outward potassium currents (Ito ) in rat atrial myocytes to identify potential targets in the context of ion channel currents. METHODS: The Ito characteristics in rat atrial myocytes were recorded using a whole-cell patch-clamp technique...
2024: Frontiers in Pharmacology
#30
JOURNAL ARTICLE
Yu-Ning Huang, Kun-Chuan Chen, Jen-Hung Wang, Yun-Kuan Lin
Burn injuries cause severe pain, infection risks, psychological distress, financial burdens, and mortality, necessitating effective care. Aloe vera, a traditional burn remedy, shows wound healing potential, but its analgesic effects and efficacy with varying burn severity are uncertain. This study aims to investigate aloe vera's impact on wound healing, pain management, and infection prevention in burn patients. A systematic search on PubMed, Embase, and CENTRAL was performed on 9th October 2023 for randomized controlled trials (RCTs)...
April 12, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
#31
JOURNAL ARTICLE
Manpreet Kaur, Prerna Gulati, Sugandha Verma, Parul Khare, Ruchi Garg, Jahnobi Dutta, Kumuda Rao
OBJECTIVE: This research assessed the efficiencies of aloe vera, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of OLP. MATERIALS AND METHODS: A total of 120 participants diagnosed with oral lichen planus (OLP) were equally divided into three groups and treated with: aloe vera, (Group A), 0.1% triamcinolone acetonide (Group B), and 5% amlexanox (Group C) topical medicaments. The patients were evaluated for pain, using the visual analogue scale (VAS)...
February 2024: Journal of Pharmacy & Bioallied Sciences
#32
JOURNAL ARTICLE
Mehak Tariq, Vishwanath V Jalli, J Dhurubatha, Reeturaj Medhi, Kanchan Malawat, Inderjit M Gowdar, Sugandha Arya
AIM: The aim of the study is to compare the clinical efficacy of both the topical agents-aloe vera gel and Kenacort oral paste (0.1% triamcinolone acetonide) in patients with minor aphthous stomatitis. MATERIALS AND METHODS: 60 patients were recruited for the study and were randomly divided into two groups-Group A (aloe vera gel group) and Group B (Kenacort oral paste group). The baseline parameters were taken and recorded on the day of the first visit which included ulcer size, pain, and burning sensation...
February 2024: Journal of Pharmacy & Bioallied Sciences
#33
JOURNAL ARTICLE
V P Aswathy, Aarti Bains, Kandi Sridhar, Prince Chawla, Minaxi Sharma, Nemat Ali, Abdul Malik, Gulden Goksen
In recent years, there increment demand for healthier food options that can replace high-fat ingredients in bakery products without compromising their taste and texture. This research was focused on a formulation study of the blend of nano polysaccharides derived from aloe vera and guar gum at various concentrations. This study selected the blend concentration of 1 % aloe vera mucilage (AM) and 1 % guar gum (GG) due to its optimal gelling properties. Different magnetic stirring time durations were employed to formulate AGB (aloe vera guar gum blend)...
April 7, 2024: International Journal of Biological Macromolecules
#34
JOURNAL ARTICLE
Diwanshi Sharma, Ashima Sharma, Ritu Bala, Baljit Singh
Recently, various innovative advancements have been made in carbohydrate research to design versatile materials for biomedical applications. The current research focuses on the development of copolymeric hydrogel wound dressings (HWD) using a combination of aloe vera (AV) - sterculia gum (SG) - poly (vinylsulfonic acid) (VSA)-based with the aim to enhancing their efficacy in drug delivery (DD) applications. These hydrogel dressings were encapsulated with levofloxacin and lidocaine to address both microbial infection and pain...
April 5, 2024: International Journal of Biological Macromolecules
#35
JOURNAL ARTICLE
Scott E McIntosh, Luanne Freer, Colin K Grissom, George W Rodway, Gordon G Giesbrecht, Marion McDevitt, Christopher H Imray, Eric L Johnson, Prativa Pandey, Jennifer Dow, Peter H Hackett
The Wilderness Medical Society convened an expert panel to develop a set of evidence-based guidelines for the prevention and treatment of frostbite. We present a review of pertinent pathophysiology. We then discuss primary and secondary prevention measures and therapeutic management. Recommendations are made regarding each treatment and its role in management. These recommendations are graded on the basis of the quality of supporting evidence and balance between the benefits and risks or burdens for each modality according to methodology stipulated by the American College of Chest Physicians...
April 5, 2024: Wilderness & Environmental Medicine
#36
JOURNAL ARTICLE
Blanca Carrasco, Gloria Zaragoza, David M Arana, Yolanda Hernández-Hermida, Juan-Ignacio Alós
INTRODUCTION: Early and adequate treatment of bloodstream infections decreases patient morbidity and mortality. The objective is to develop a preliminary method for rapid antibiotic susceptibility testing (RAST) in enterobacteria with inducible chromosomal AmpC. METHODS: RAST was performed directly on spiked blood cultures of 49 enterobacteria with inducible chromosomal AmpC. Results were read at 4, 6 and 8h of incubation. Commercial broth microdilution was considered the reference method...
April 2024: Enfermedades infecciosas y microbiologia clinica
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JOURNAL ARTICLE
Mayank Roshan, Ila Singh, Ashutosh Vats, Manisha Behera, Dravin Pratap Singh, Devika Gautam, Shiveeli Rajput, Jitesh Tarak, Gopinath Packirisamy, Sachinandan De
Antimicrobial resistance (AMR) poses a serious threat to human, animal, and plant health on a global scale. Search and elimination techniques should be used to effectively counter the spread of methicillin-resistant Staphylococcus aureus (MRSA) infections. With only a few novel drugs in clinical development, the quest for plant-based alternatives to prevent the spread of antibiotic resistance among bacteria has accelerated. Treatment of MRSA infections is challenging owing to rapidly emerging resistance mechanisms coupled with their protective biofilms...
April 3, 2024: International Microbiology: the Official Journal of the Spanish Society for Microbiology
#38
JOURNAL ARTICLE
P W Crous, E R Osieck, R G Shivas, Y P Tan, S L Bishop-Hurley, F Esteve-Raventós, E Larsson, J J Luangsa-Ard, F Pancorbo, S Balashov, I G Baseia, T Boekhout, S Chandranayaka, D A Cowan, R H S F Cruz, P Czachura, S De la Peña-Lastra, F Dovana, B Drury, J Fell, A Flakus, R Fotedar, Ž Jurjević, A Kolecka, J Mack, G Maggs-Kölling, S Mahadevakumar, A Mateos, S Mongkolsamrit, W Noisripoom, M Plaza, D P Overy, M Piątek, M Sandoval-Denis, J Vauras, M J Wingfield, S E Abell, A Ahmadpour, A Akulov, F Alavi, Z Alavi, A Altés, P Alvarado, G Anand, N Ashtekar, B Assyov, G Banc-Prandi, K D Barbosa, G G Barreto, J-M Bellanger, J L Bezerra, D J Bhat, P Bilański, T Bose, F Bozok, J Chaves, D H Costa-Rezende, C Danteswari, V Darmostuk, G Delgado, S Denman, A Eichmeier, J Etayo, G Eyssartier, S Faulwetter, K G G Ganga, Y Ghosta, J Goh, J S Góis, D Gramaje, L Granit, M Groenewald, G Gulden, L F P Gusmão, A Hammerbacher, Z Heidarian, N Hywel-Jones, R Jankowiak, M Kaliyaperumal, O Kaygusuz, K Kezo, A Khonsanit, S Kumar, C H Kuo, T Læssøe, K P D Latha, M Loizides, S M Luo, J G Maciá-Vicente, P Manimohan, P A S Marbach, P Marinho, T S Marney, G Marques, M P Martín, A N Miller, F Mondello, G Moreno, K T Mufeeda, H Y Mun, T Nau, T Nkomo, A Okrasińska, J P A F Oliveira, R L Oliveira, D A Ortiz, J Pawłowska, M À Pérez-De-Gregorio, A R Podile, A Portugal, N Privitera, K C Rajeshkumar, I Rauf, B Rian, A Rigueiro-Rodríguez, G F Rivas-Torres, P Rodriguez-Flakus, M Romero-Gordillo, I Saar, M Saba, C D Santos, P V S R N Sarma, J L Siquier, S Sleiman, M Spetik, K R Sridhar, M Stryjak-Bogacka, K Szczepańska, H Taşkın, D S Tennakoon, D Thanakitpipattana, J Trovão, I Türkekul, A L van Iperen, P van 't Hof, G Vasquez, C M Visagie, B D Wingfield, P T W Wong, W X Yang, M Yarar, O Yarden, N Yilmaz, N Zhang, Y N Zhu, J Z Groenewald
Novel species of fungi described in this study include those from various countries as follows: Australia , Aschersonia mackerrasiae on whitefly, Cladosporium corticola on bark of Melaleuca quinquenervia , Penicillium nudgee from soil under Melaleuca quinquenervia , Pseudocercospora blackwoodiae on leaf spot of Persoonia falcata , and Pseudocercospora dalyelliae on leaf spot of Senna alata . Bolivia , Aspicilia lutzoniana on fully submersed siliceous schist in high-mountain streams, and Niesslia parviseta on the lower part and apothecial discs of Erioderma barbellatum on a twig...
June 2023: Persoonia
#39
JOURNAL ARTICLE
Aditya Jain, Shikha Yadav, Javed Khan
Wound healing is crucial for maintaining skin integrity and preventing complications from external threats. Various plants, such as Achillea millefolium, Aloe vera, Curcuma longa, Calendula officinalis, Camellia sinensis, Azadirachta indica, and Plantago, have demonstrated wound healing capabilities and have been used in herbal medicine for wound care. NLCs are second-generation lipid nanoparticles, blending solid and liquid lipids to improve medication loading and limit leakage. NLCs have been used in various applications, including cosmeceuticals, chemotherapy, gene therapy, and brain targeting...
April 1, 2024: Current Pharmaceutical Biotechnology
#40
JOURNAL ARTICLE
Cyrus Mugo, Oluwasanmi Adedokun, Oluwafemi David Alo, Nnenna Ezeokafor, Sylvester Adeyemi, Zipporah Kpamor, Leila Madueke, Ezekiel James, Sylvia Bolanle Adebajo, Bazghina-Werq Semo
During the COVID-19 pandemic, HIV programs scaled up differentiated service delivery (DSD) models for people living with HIV (PLHIV). We evaluated the effects of COVID-19 on HIV service delivery and viral suppression in facilities in Northern Nigeria, and determined factors associated with viral suppression among adolescents and adults. We analysed a cross-sectional survey data from facility heads, and retrospective, routinely collected patient data from 63 facilities for PLHIV ≥10 years old in care between April 2019-March 2021, defining study periods as "pre-COVID-19" (before April 2020) and "during COVID-19" (after April 2020)...
2024: PloS One
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