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JOURNAL ARTICLE
Joanna N Assadourian, Eric D Peterson, Anand Gupta, Ann M Navar
BACKGROUND: Dietary supplement use is prevalent in the general US population, but little is known regarding the driving reasons for their use among those with atherosclerotic cardiovascular disease (ASCVD). METHODS AND RESULTS: Data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to March 2020 were used to identify adults with ASCVD. Supplement use was assessed by interviewers using label review, and surveys captured self-reported reasons for use...
May 3, 2024: Journal of the American Heart Association
#22
JOURNAL ARTICLE
Jordan Tyris, Gina Dwyer, Kavita Parikh, Anand Gourishankar, Shilpa Patel
No abstract text is available yet for this article.
May 3, 2024: Hospital Pediatrics
#23
JOURNAL ARTICLE
Tanmoy Maji, Mala Mahto, Sudhir Kumar, Utpal Anand, Rajeev N Priyadarshi, Rahul Arya, Ramesh Kumar
AIM: Hepatogenous diabetes (HD) is frequently underestimated among cirrhosis patients. The current study assessed the magnitude, clinical characteristics, and implications of HD in cirrhosis patients as compared to the patients with type-2 diabetes mellitus (T2DM) and non-diabetes (ND) cirrhosis. METHODS: In a prospective observational study, 338 consecutive eligible cirrhosis patients were screened for diabetes mellitus. A 2-hour oral glucose tolerance test (OGTT) was used to detect HD...
2024: Journal of Clinical and Experimental Hepatology
#24
JOURNAL ARTICLE
Shivesh Anand, Alessandra Fusco, Cemre Günday, Nazende Günday-Türeli, Giovanna Donnarumma, Serena Danti, Lorenzo Moroni, Carlos Mota
Approximately 740 million symptomatic patients are affected by otitis media every year. Being an inflammatory disease affecting the middle ear, it is one of the primary causes of tympanic membrane (TM) perforations, often resulting in impaired hearing abilities. Antibiotic therapy using broad-spectrum fluoroquinolones, such as ciprofloxacin (CIP), is frequently employed and considered the optimal route to treat otitis media. However, patients often get exposed to high dosages to compensate for the low drug concentration reaching the affected site...
August 2024: Bioactive Materials
#25
JOURNAL ARTICLE
Jhillika Patel, Divya Anand, Chandravathi Sayani, Alyanna Tam, Anna Green, Brian M Katt
INTRODUCTION: Disparities in early orthopaedic experiences among medical students prompt a critical examination of factors influencing the availability and nature of these exposures. While the current body of literature underscores the significance of early surgical exposure and mentorship in medical education, a notable gap exists in investigating early orthopaedic exposure and its specific impact on students from diverse backgrounds. METHODS: A 16-item questionnaire, approved by our institutional review board, was administered to fourth-year medical students (MS4) and first-year orthopaedic residents (PGY-1) across U...
April 2024: Curēus
#26
JOURNAL ARTICLE
Yash Verma, R S Anand
Speech and hearing impairments are among the most common problems in Indian societies. It can affect anyone, whether children, adults, or more. Many different treatments can help to overcome hearing problems. Different types of hearing aids and cochlear implants help amplify sounds for better hearing. The type of language known as sign language is very scientific and has its grammar and syntax. Still, due to a need for more awareness among hard-of-hearing persons, they need to be made familiar with the institutions where they can learn and equip themselves for communication...
May 15, 2024: Heliyon
#27
REVIEW
Anand Krishnan, Valerie M K Verge, Douglas W Zochodne
Peripheral nerves are functional networks in the body. Disruption of these networks induces varied functional consequences depending on the types of nerves and organs affected. Despite the advances in microsurgical repair and understanding of nerve regeneration biology, restoring full functions after severe traumatic nerve injuries is still far from achieved. While a blunted growth response from axons and errors in axon guidance due to physical barriers may surface as the major hurdles in repairing nerves, critical additional cellular and molecular aspects challenge the orderly healing of injured nerves...
2024: Handbook of Clinical Neurology
#28
RANDOMIZED CONTROLLED TRIAL
Keir E J Philip, Sara C Buttery, Sarah Bowen, Adam Lewis, Edmund Jeffery, Saeed M Alghamdi, Parris Williams, Ali M Alasmari, Abdullah S Alsulayyim, Christopher M Orton, Francesca Conway, Ley Chan, Bavithra Vijayakumar, Anand Tana, James Tonkin, Alexis Perkins, Justin L Garner, Karthikan Srikanthan, Ahmed Sadaka, Matthew J Pavitt, Winston Banya, Adam Lound, Sarah Elkin, Michael I Polkey, William D-C Man, Keir Lewis, Phoene Cave, Daisy Fancourt, Nicholas S Hopkinson
BACKGROUND: Singing for lung health (SLH) is an arts-based breathing control and movement intervention for people with long-term respiratory conditions, intended to improve symptoms and quality of life. Online, remotely delivered programmes might improve accessibility; however, no previous studies have assessed the effectiveness of this approach. METHODS: We conducted an assessor-blind randomised controlled trial comparing the impact of 12 weeks of once-weekly online SLH sessions against usual care on health-related quality of life, assessed using the RAND 36-Item Short Form Health Survey (SF-36) Mental Health Composite (MHC) and Physical Health Composite (PHC) scores...
May 2, 2024: BMJ Open Respiratory Research
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MULTICENTER STUDY
Suman Kanungo, Uttaran Bhattacharjee, Aslesh O Prabhakaran, Rakesh Kumar, Prabu Rajkumar, Sumit Dutt Bhardwaj, Alok Kumar Chakrabarti, Girish Kumar C P, Varsha Potdar, Byomkesh Manna, Ritvik Amarchand, Avinash Choudekar, Giridara Gopal, Krishna Sarda, Kathryn E Lafond, Eduardo Azziz-Baumgartner, Siddhartha Saha, Lalit Dar, Anand Krishnan
BACKGROUND: Limited data exists regarding risk factors for adverse outcomes in older adults hospitalized with Community-Acquired Pneumonia (CAP) in low- and middle-income countries such as India. This multisite study aimed to assess outcomes and associated risk factors among adults aged ≥60 years hospitalized with pneumonia. METHODS: Between December 2018 and March 2020, we enrolled ≥60-year-old adults admitted within 48 hours for CAP treatment across 16 public and private facilities in four sites...
2024: PloS One
#30
JOURNAL ARTICLE
Sandeep Kumar, Alok Shukla, Surya Pratap Singh, Rishi Kant Singh, Anand Kumar Patel, Praveen Kumar Verma, Sanjay Kumar, Naveen Kumar, Varsha Singh, Kirti Wasnik, Arbind Acharya
The therapeutic potential of chemically synthesized AuNPs has been demonstrated in various types of cancer. However, gold nanoparticles (AuNPs) synthesized using typical chemical methods have concerns regarding their environmental safety and adverse impact on human well-being. To overcome this issue, we used an environmentally friendly approach in which gold nanoparticles were synthesized using Moringa oleifera leaf extract (MLE). The present research was mainly focused on the biosynthesis and characterization of gold nanoparticles (AuNPs) using Moringa oleifera leaf extract (MLE-AuNPs) and explore its anticancer potential against Dalton's Lymphoma (DL) cells...
May 2, 2024: Cell Biochemistry and Biophysics
#31
JOURNAL ARTICLE
Vatsala Anand, Deepika Koundal, Wael Y Alghamdi, Bayan M Alsharbi
Diabetic retinopathy is a condition that affects the retina and causes vision loss due to blood vessel destruction. The retina is the layer of the eye responsible for visual processing and nerve signaling. Diabetic retinopathy causes vision loss, floaters, and sometimes blindness; however, it often shows no warning signals in the early stages. Deep learning-based techniques have emerged as viable options for automated illness classification as large-scale medical imaging datasets have become more widely available...
2024: Frontiers in artificial intelligence
#32
JOURNAL ARTICLE
Loïc Deblais, Mary Drozd, Anand Kumar, Janet Antwi, James Fuchs, Rahul Khupse, Yosra A Helmy, Gireesh Rajashekara
INTRODUCTION: Control of Campylobacter from farm to fork is challenging due to the frequent emergence of antimicrobial-resistant isolates. Furthermore, poultry production systems are known reservoirs of Campylobacter . The twin-arginine translocation (Tat) pathway is a crucial bacterial secretion system that allows Campylobacter to colonize the host intestinal tract by using formate as the main source of energy. However, Tat pathway is also a major contributing factor for resistance to copper sulfate (CuSO4 )...
2024: Frontiers in Microbiology
#33
EDITORIAL
Abha Deshpande, Ryan Varghese, Priyanka Roy, Mainak Bardhan, Ayush Anand
No abstract text is available yet for this article.
May 2024: Annals of Medicine and Surgery
#34
JOURNAL ARTICLE
Somenath Das, Anand Kumar Chaudhari
The present investigation entails the encapsulation of Apium graveolens essential oil into chitosan nanobiopolymer (AGEO-Ne) and assessment of its efficacy against Fusarium verticill i oides contamination and fumonisins biosynthesis in stored rice ( Oryza sativa L.) samples. The AGEO was encapsulated through ionic gelation process and characterized by scanning electron microscopy (SEM), Dynamic light scattering (DLS), X-ray diffractometry (XRD), and Fourier transform infrared spectroscopy (FTIR) analyses. The AGEO exhibited bi-phasic delivery pattern from chitosan matrix...
May 15, 2024: Heliyon
#35
JOURNAL ARTICLE
Leeberk Raja Inbaraj, Abi Manesh, C Ponnuraja, Adhin Bhaskar, Vignes Anand Srinivasalu, Bella Devaleenal Daniel
BACKGROUND: Despite several incremental improvements in the management of tuberculous meningitis (TBM), the mortality rates remain high. In spite of national and international guidelines, variation in the choice, dose, and duration of drugs exist between countries and clinicians. We propose to evaluate a shorter and more effective regimen containing agents with augmented intracerebral drug exposure and anti-inflammatory approaches to improve disability-free survival among patients with TBM...
May 2, 2024: Trials
#36
JOURNAL ARTICLE
Hamidreza Hosseinpour, Tanya Anand, Omar Hejazi, Christina Colosimo, Sai Krishna Bhogadi, Audrey Spencer, Adam Nelson, Michael Ditillo, Louis J Magnotti, Bellal Joseph
INTRODUCTION: Whole blood (WB) has recently gained increased popularity as an adjunct to the resuscitation of hemorrhaging civilian trauma patients. We aimed to assess the nationwide outcomes of using WB as an adjunct to component therapy (CT) versus CT alone in resuscitating geriatric trauma patients. METHODS: We performed a 5-y (2017-2021) retrospective analysis of the Trauma Quality Improvement Program. We included geriatric (age, ≥65 y) trauma patients presenting with hemorrhagic shock (shock index >1) and requiring at least 4 units of packed red blood cells in 4 h...
April 30, 2024: Journal of Surgical Research
#37
JOURNAL ARTICLE
Brijesh Kumar, Alvee Saluja, Abhishek Juneja, Kuljeet S Anand, Kallur N Saraswathy, Imnameren Longkumer, Rajinder K Dhamija
BACKGROUND AND OBJECTIVES: The role of various genetic markers including alpha synuclein, Parkin, etc., is known in the pathogenesis of Parkinson's disease (PD). Novel genetic markers including paraoxonase 1 (PON1) have also been linked to PD pathogenesis in recent studies. The PON1 L55M allele carriers may have defective clearance of environmental toxins and may result in increased susceptibility to PD. Hence, we studied the role of PON1 L55M polymorphism in PD among a North Indian population...
March 1, 2024: Neurology India
#38
JOURNAL ARTICLE
Prashant Sharma, Amol Patil, Sonakshi Sharma, Tanisha Rout, Pragati Hemgude, Anand Sabane
The aim of this study was to evaluate specific single nucleotide polymorphisms (SNP) of transforming growth factor-beta (TGF-β) (rs1800469) and insulin-like growth factor-1 (IGF-1) (rs17032362) genes in Class II individuals with a normal maxilla and retrognathic (short) mandible.
April 30, 2024: Folia Medica
#39
JOURNAL ARTICLE
Vardhmaan Jain, Birju Rao, Leonardo Knijnik, Anand D Shah, Michael S Lloyd, Mikhael F El-Chami, Neal Bhatia, Stacy Westerman, Faisal M Merchant
No abstract text is available yet for this article.
April 2024: Heart rhythm O2
#40
REVIEW
Lee M Jeys, Joachim Thorkildsen, Vineet Kurisunkal, Ajay Puri, Pietro Ruggieri, Matthew T Houdek, Richard A Boyle, Walid Ebeid, Eduardo Botello, Guy V Morris, Minna K Laitinen, Adesegun Abudu, Keisuke Ae, Manish Agarwal, Vivek Ajit Singh, Toru Akiyama, Jose I Albergo, John Alexander, Bugra Alpan, Ahmed Aoude, Apichat Asavamongkolkul, William Aston, Thomas Baad-Hansen, Tessa Balach, Joseph Benevenia, Peter Bergh, Nicholas Bernthal, Odion Binitie, Michele Boffano, Jos Bramer, Harriet Branford White, Bernadette Brennan, Jorge Cabrolier, Jose A Calvo Haro, Domenico A Campanacci, Rodrigo Cardoso, Richard Carey Smith, Nicolas Casales Fresnga, Jose M Casanova, Oscar Ceballos, Chung M Chan, Yang-Guk Chung, Miguel A Clara-Altamirano, Gillian Cribb, Solomon Dadia, Dietmar Dammerer, Marieke de Vaal, Javier Delgado Obando, Shaneel Deo, Claudia Di Bella, Davide M Donati, Makoto Endo, Levent Eralp, Bulent Erol, Scott Evans, Will Eward, Fabrice Fiorenza, Joao Freitas, Philipp T Funovics, Marcos Galli Serra, Michelle Ghert, Kanishka Ghosh, Luis C Gomez Mier, Jesus Gomez Vallejo, Anthony Griffin, Ashish Gulia, Maurice Guzman, Jendrik Hardes, John Healey, Adriana Hernandez, Asle Hesla, Chindanai Hongsaprabhas, Francis Hornicek, Keith Hosking, Shintaro Iwata, Jake Jagiello, Luke Johnson, Andy Johnston, Min Joo, Paul Jutte, Bilal Kapanci, Zeeshan Khan, Hiroshi Kobayashi, Yehuda Kollender, Sebastian Koob, Daniel Kotrych, Louis-Romee Le Nail, Pawel Legosz, Burkhard Lehner, Andreas Leithner, Valerae Lewis, Peng Lin, Francisco Linares, Santiago Lozano Calderon, Ashish Mahendra, Ferdiansyah Mahyudin, Eric Mascard, Jean-Camille Mattei, Louise McCullough, Manuel R Medellin Rincon, Rhidian Morgan-Jones, Diego J Moriel Garcesco, Sophie Mottard, Robert Nakayama, Prashant Narhari, Gary O'Toole, Oliveira Vania, André Olivier, Mohamed Omar, Eduardo Ortiz-Cruz, Harzem Ozger, Korhan Ozkan, Emanuela Palmerini, Panayiotis Papagelopoulos, Michael Parry, Sam Patton, Michael M Petersen, Gerard Powell, Mark Puhaindran, Anand Raja, Raja B Rajasekaran, Lauris Repsa, Mickael Ropars, Andrea Sambri, Thomas Schubert, Ahmad Shehadeh, Geoffrey Siegel, Scott Sommerville, Andre Spiguel, Jonathan Stevenson, Gwen Sys, Thomas Temple, Frank Traub, Hiroyuki Tsuchiya, Juan Valencia, Michel Van de Sande, Gualter Vaz, Roberto Velez Villa, Oleg Vyrva, Hazem Wafa, Wan I Wan Faisham Numan, Edward Wang, David Warnock, Joel Werier, Kwok-Chuen Wong, Yamamoto Norio, Ye Zhaoming, Suraya Zainul Abidin, Tomas Zamora, Juan P Zumarraga, Ghaith Abou-Nouar, Carsten Gebert, R L Randall
Chondrosarcoma is the second most common surgically treated primary bone sarcoma. Despite a large number of scientific papers in the literature, there is still significant controversy about diagnostics, treatment of the primary tumour, subtypes, and complications. Therefore, consensus on its day-to-day treatment decisions is needed. In January 2024, the Birmingham Orthopaedic Oncology Meeting (BOOM) attempted to gain global consensus from 300 delegates from over 50 countries. The meeting focused on these critical areas and aimed to generate consensus statements based on evidence amalgamation and expert opinion from diverse geographical regions...
May 1, 2024: Bone & Joint Journal
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