Harry A Smith, Iain Templeman, Max Davis, Tommy Slater, David J Clayton, Ian Varley, Lewis J James, Benita Middleton, Jonathan D Johnston, Leonidas G Karagounis, Kostas Tsintzas, Dylan Thompson, Javier T Gonzalez, Jean-Philippe Walhin, James A Betts
CONTEXT: Skeletal muscle plays a central role in the storage, synthesis, and breakdown of nutrients, yet little research has explored temporal responses of this human tissue, especially with concurrent measures of systemic biomarkers of metabolism. OBJECTIVE: To characterise temporal profiles in skeletal muscle expression of genes involved in carbohydrate metabolism, lipid metabolism, circadian clocks, and autophagy and descriptively relate them to systemic metabolites and hormones during a controlled laboratory protocol...
May 23, 2024: Journal of Clinical Endocrinology and Metabolism