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JOURNAL ARTICLE
Slavica Kochovska, Rajam Iyer, Sungwon Chang, Diana Ferreira, Vanessa N Brunelli, Irina Kinchin, Danny J Eckert, Joseph Clark, Jacob Sandberg, Magnus Ekström, David Currow, Sujeet Rajan
There are no known estimates of the prevalence, severity and impacts from breathlessness in low- and middle-income countries. This study aimed to explore the prevalence, severity, self-attributed underlying conditions and impacts of breathlessness limiting exertion in community-dwelling adults in India. This exploratory, population-based online survey recruited a pre-planned sample of 3,000 adult respondents stratified by age, sex and rurality (quotas as per the 2011 Indian National Census). Measures included: demographics; breathlessness limiting exertion (modified Medical Research [mMRC] scale); health-related quality of life (EQ-5D-5L); and disability (World Health Organisation's Disability Assessment Schedule 2...
2024: PLOS Glob Public Health
#2
COMPARATIVE STUDY
Ying Li, XiaoGuang Li, Haseeb Ahmad
Given the importance of ICT diffusion in the development of the financial sector, this analysis is an effort to analyze the transmission channels between the two in high-income and middle and low-income economies over 2001-2019. We have used three variables, including the ICT index, individuals using the internet, and mobile subscribers, to represent ICT and three indices, including the financial development index, financial institution index, and financial market index, to make our results reliable and robust...
2024: PloS One
#3
MULTICENTER STUDY
Suman Kanungo, Uttaran Bhattacharjee, Aslesh O Prabhakaran, Rakesh Kumar, Prabu Rajkumar, Sumit Dutt Bhardwaj, Alok Kumar Chakrabarti, Girish Kumar C P, Varsha Potdar, Byomkesh Manna, Ritvik Amarchand, Avinash Choudekar, Giridara Gopal, Krishna Sarda, Kathryn E Lafond, Eduardo Azziz-Baumgartner, Siddhartha Saha, Lalit Dar, Anand Krishnan
BACKGROUND: Limited data exists regarding risk factors for adverse outcomes in older adults hospitalized with Community-Acquired Pneumonia (CAP) in low- and middle-income countries such as India. This multisite study aimed to assess outcomes and associated risk factors among adults aged ≥60 years hospitalized with pneumonia. METHODS: Between December 2018 and March 2020, we enrolled ≥60-year-old adults admitted within 48 hours for CAP treatment across 16 public and private facilities in four sites...
2024: PloS One
#4
JOURNAL ARTICLE
Aryan Gupta, Justin Yu, Elio J Challita, Janet Standeven, M Saad Bhamla
High-cost DNA extraction procedures pose significant challenges for budget-constrained laboratories. To address this, we introduce OpenCell, an economical, open-source, 3-in-1 laboratory device that combines the functionalities of a bead homogenizer, a microcentrifuge, and a vortex mixer. OpenCell utilizes modular attachments that magnetically connect to a central rotating brushless motor. This motor couples to an epicyclic gearing mechanism, enabling efficient bead homogenization, vortex mixing, and centrifugation within one compact unit...
2024: PloS One
#5
JOURNAL ARTICLE
Flavia Ismael, Artur Ramos, Rafael Erik de Menezes, Regina Maura Zetone Grespam, Cibele Cristine Remondes Sequeira, Jair de Jesus Mari, João Mauricio Castaldelli-Maia
São Caetano do Sul, a city in southeastern Brazil, boasts exemplary social indicators and healthcare services, with a population of 162,763 and a density of 9,736.03 inhabitants/km². Allocating 25% of its budget to healthcare, the city's mental healthcare services adhere to the National Mental Health Policy. Structured services include a CAPS-II, CAPS-AD, outpatient teams, and teams in various locations. Initiatives since 2000 include inaugurating a CAPS-AD in 2006, a psychiatric emergency service in 2010, and a CAPS-II in 2016, relocating CAPS-AD in 2019, and establishing the Cuca Legal Project in 2022...
May 2, 2024: Trends in Psychiatry and Psychotherapy
#6
REVIEW
Raj Kalaria, Gladys Maestre, Simin Mahinrad, Daisy M Acosta, Rufus Olusola Akinyemi, Suvarna Alladi, Ricardo F Allegri, Faheem Arshad, David Oluwasayo Babalola, Olusegun Baiyewu, Thomas H Bak, Tarek Bellaj, David K Brodie-Mends, Maria C Carrillo, Kaputu-Kalala-Malu Celestin, Albertino Damasceno, Ranil Karunamuni de Silva, Rohan de Silva, Mamuka Djibuti, Anna Jane Dreyer, Ratnavalli Ellajosyula, Temitope H Farombi, Robert P Friedland, Noe Garza, Antoine Gbessemehlan, Eliza Eleni-Zacharoula Georgiou, Ishtar Govia, Lea T Grinberg, Maëlenn Guerchet, Seid Ali Gugssa, Joy Louise Gumikiriza-Onoria, Eef Hogervorst, Michael Hornberger, Agustin Ibanez, Masafumi Ihara, Thomas Gregor Issac, Linus Jönsson, Wambui M Karanja, Joseph H Lee, Iracema Leroi, Gill Livingston, Facundo Francisco Manes, Lingani Mbakile-Mahlanza, Bruce L Miller, Christine Wayua Musyimi, Victoria N Mutiso, Noeline Nakasujja, David M Ndetei, Sam Nightingale, Gabriela Novotni, Primrose Nyamayaro, Solomon Nyame, Julius A Ogeng'o, Adesola Ogunniyi, Maira Okada de Oliveira, Njideka U Okubadejo, Martin Orrell, Stella-Maria Paddick, Margaret A Pericak-Vance, Zvezdan Pirtosek, Felix Claude Victor Potocnik, Rema Raman, Mie Rizig, Mónica Rosselli, Marufjon Salokhiddinov, Claudia L Satizabal, Diego Sepulveda-Falla, Sudha Seshadri, Claire E Sexton, Ingmar Skoog, Peter H St George-Hyslop, Claudia Kimie Suemoto, Prekshy Thapa, Chinedu Theresa Udeh-Momoh, Victor Valcour, Jeffery M Vance, Mathew Varghese, Jaime H Vera, Richard W Walker, Henrik Zetterberg, Yared Z Zewde, Ozama Ismail
Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations...
May 2, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
#7
JOURNAL ARTICLE
Seung Hoon Kim, Hyunkyu Kim, Sung Hoon Jeong, Eun-Cheol Park
BACKGROUND: As income and health are closely related, retirement is considered undesirable for health. Many studies have shown the association between pension and health, but no research has considered the association between contribution-based public pensions or their types and health. OBJECTIVE: This study investigates the association between the type of contributory public pension and depressive symptoms among older adults. METHODS: We analyzed the data of 4541 older adults who participated in the South Korea Welfare Panel Study (2014-2020)...
May 2, 2024: JMIR Public Health and Surveillance
#8
REVIEW
Navaneetha Sasikumar, Pranoti Toshniwal, Praveen Reddy Bayya, Abish Sudhakar, Raman Krishna Kumar
Duct-dependent pulmonary circulation has traditionally been addressed by the Blalock-Taussig-Thomas shunts (BTTS). Recently, catheter-based alternatives such as ductal stenting have emerged as a particularly advantageous option, especially in resource-constrained settings. This article delves into the nuances of ductal stenting within low-resource environments, highlighting its relative ease of application, reduced morbidity, and cost-effectiveness as key factors in its favor. Comparisons in mortality between the two procedures are however likely to be confounded by selection biases...
May 2, 2024: Pediatric Cardiology
#9
REVIEW
Piero Alberti, Jola Bytyci, Jessy Jindal, Michael Stephanou, Lucy Thompson, Yedidiah Tilahun, Yuxin Ying, Annabel Killen, Emery Manirambona, Alliance Niyukuri, Kokila Lakhoo, Kathryn Ford
BACKGROUND: Literature on paediatric surgical conditions in low- and middle-income countries (LMICs) remains limited. As a common emergency, timely treatment of testicular torsion acts as a benchmark of adequate emergency service delivery in paediatric surgery. This scoping study aims to synthesise all existing literature on paediatric testicular torsion in LMICs. METHODS: A database search was conducted by the OxPLORE global paediatric surgery research group to identify studies containing the terms 'testicular torsion' or 'acute scrotum' originating from LMICs...
May 2, 2024: Pediatric Surgery International
#10
JOURNAL ARTICLE
Robert Shen, Arthur Todingbua, Hans Angelius Suharto, Meilina Imelda, Monika Hartono
BACKGROUND: Conjoined twins (CT), which used to be historically defined as "monstrous human" and previously so-called Siamese twins in the early eighteenth century, are one of the very rare congenital malformations with an uncertain etiology and complex yet remain inconclusively debatable regarding its pathophysiological mechanisms of fusion and fission theories. Among all types of CT, parasitic CT, especially the pygopagus sub-type, is exceedingly rarer. To the best of the authors' knowledge, no parasitic CT had been reported in Papua, and this is the first finding in South Papua...
May 2, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#11
REVIEW
Mohamed E Abdel-Latif, Olive Tan, Michelle Fiander, David A Osborn
BACKGROUND: Respiratory distress occurs in up to 7% of newborns, with respiratory support (RS) provided invasively via an endotracheal (ET) tube or non-invasively via a nasal interface. Invasive ventilation increases the risk of lung injury and chronic lung disease (CLD). Using non-invasive strategies, with or without minimally invasive surfactant, may reduce the need for mechanical ventilation and the risk of lung damage in newborn infants with respiratory distress. OBJECTIVES: To evaluate the benefits and harms of nasal high-frequency ventilation (nHFV) compared to invasive ventilation via an ET tube or other non-invasive ventilation methods on morbidity and mortality in preterm and term infants with or at risk of respiratory distress...
May 2, 2024: Cochrane Database of Systematic Reviews
#12
REVIEW
Peter Langer, Lukas John, Ina Monsef, Christof Scheid, Vanessa Piechotta, Nicole Skoetz
BACKGROUND: Multiple myeloma (MM) is a haematological malignancy that is characterised by proliferation of malignant plasma cells in the bone marrow. For adults ineligible to receive high-dose chemotherapy and autologous stem cell transplant, the recommended treatment combinations in first-line therapy generally consist of combinations of alkylating agents, immunomodulatory drugs, and proteasome inhibitors. Daratumumab is a CD38-targeting, human IgG1k monoclonal antibody recently developed and approved for the treatment of people diagnosed with MM...
May 2, 2024: Cochrane Database of Systematic Reviews
#13
JOURNAL ARTICLE
Rui Han Liu, Wayne Manana, Travis T Tollefson, Faustin Ntirenganya, David A Shaye
PURPOSE OF REVIEW: As the most common congenital craniofacial defect, patients with cleft lip -palate (CLP) experience morbidity and social stigma, particularly in low-income and middle-income countries (LMICs) such as those of sub-Saharan Africa (SSA). Delays in treatment secondary either to lack of awareness, skills, equipment and consumables; poor health infrastructure, limited resources or a combination of them, has led to SSA having the highest rates of death and second highest rates of disability-adjusted life years in patients with CLP globally...
April 24, 2024: Current Opinion in Otolaryngology & Head and Neck Surgery
#14
REVIEW
Munazieraa Ab Aziz, Ng Ai Kah, Maslinor Ismail, Hazreen Abdul Majid
Low- and lower-middle-income countries bear the greatest burden of anemia, particularly those living in rural settings such as an indigenous community. The objective of this systematic review is to recognize the prevalence of anemia and its determinants among the Orang Asli children in Peninsular Malaysia. A web-based search of PubMed, Web of Science, Scopus, Medline, and ProQuest from January 2000 to June 2022, using specified search/MeSH (Medical Subject Headings) terms and keywords, was conducted. The search identified studies reported the prevalence of anemia among the children of Orang Asli and its causes...
May 2, 2024: Asia-Pacific Journal of Public Health
#15
JOURNAL ARTICLE
Xin-Yi Zhou, Qi-Qi Ke, Wei-Yu Qiu, Yao-Xia Li, Qin-Yang Wu, Qiu-Yun Ye, Qiao-Hong Yang
AIMS: This study aimed to explore the change trend and group heterogeneity of psychosocial adjustment level and to determine its influencing factors among young and middle-aged patients with first-episode acute myocardial infarction (AMI). METHODS AND RESULTS: The Psychosocial Adjustment Scale of Illness was used to assess the psychosocial adjustment level of the patients at 1, 3, and 6 months after discharge, respectively. Data were analyzed using Pearson correlation analysis, generalized estimating equations, and growth mixed models...
May 2, 2024: European Journal of Cardiovascular Nursing
#16
JOURNAL ARTICLE
Hong Tham Pham, Tuong-Anh Mai-Phan, Anh Dung Nguyen, Van-Quang-Huy Nguyen, Minh-Hoang Tran
BACKGROUND: Antimicrobial Stewardship Programs (ASP) have been applied widely in high-resource countries to prevent surgical site infections (SSI). Evidence favoring ASP interventions (ASPi) in gastrointestinal surgeries from low and middle-income countries has been limited, especially in antimicrobial prophylaxis. We aimed to investigate this gap at a Vietnamese tertiary hospital. METHODS: We conducted a retrospective cohort study on patients undergoing clean-contaminated surgeries in 2015 who received standard of care (SoC) or SoC + ASPi...
2024: Frontiers in Medicine
#17
JOURNAL ARTICLE
Francesco Schievano, Kissa W Mwamwitwa, Seth Kisenge, Elice Mmari, Alemayehu Duga, Siphesihle Nhlabatsi, Cassandra Elagbaje, Abiodun Sadikat Abiola, Solomon Getnet Meshesha, Silvia Pagani, Riccardo Lora, Alberto Sabaini, Frank Cobelens, Linda Härmark, Eric Battey Eko, Anita Conforti, Mauro Venegoni, Lara Magro, Ugo Moretti
INTRODUCTION: Efforts to improve medication access in low-and middle-income countries, particularly in Sub-Saharan Africa, have made progress, especially in the fight against infectious diseases such as tuberculosis. However, challenges exist in establishing effective pharmacovigilance systems. The PhArmacoVIgilance Africa (PAVIA) project was committed to enhancing pharmacovigilance in Tanzania, Eswatini, Nigeria, and Ethiopia, with an emphasis on anti-tuberculosis drugs, utilizing various methods, including training...
2024: Frontiers in Medicine
#18
JOURNAL ARTICLE
Chunlan Yu, Yan Wu, Yuli Zhang, Mei Li, Xin Xie, Longsheng Xie
BACKGROUND: In China, little is known about the hope level of older people living with HIV/AIDS (PLWHA). This study was to examine the hope level of older PLWHA in China and identify related factors. METHODS: This cross-sectional study was conducted in Sichuan province in China among older PLWHA. A standardized self-report questionnaire, the Herth Hope Index, was adopted. Multiple linear regression was used to identify factors influencing hope level. p -values <0...
2024: Frontiers in Public Health
#19
JOURNAL ARTICLE
Alfred K Doku, John Tetteh, Juliette Edzeame, Ron J G Peters, Charles Agyemang, Elom Hillary Otchi, Alfred Edwin Yawson
Cardiovascular diseases (CVD) are the leading cause of death worldwide, with 80% of these deaths occurring in low-middle income countries (LMICs). In Ghana and across Africa, CVDs have emerged as the leading causes of death primarily due to undetected and under treated hypertension, yet less than 5% of resources allocated to health in these resource-poor countries go into non-communicable diseases (NCD) including CVD prevention and management. Consequently, most countries in Africa do not have contextually appropriate and sustainable health system framework to prevent, detect and manage CVD to achieve Universal Health Coverage (UHC) in CVD care through improved Primary Health Care (PHC) with the aim of achieving Sustainable Development Goals (SDG) in CVD/NCD...
2024: Frontiers in Public Health
#20
JOURNAL ARTICLE
Mekdes Mengesha Jemberie, Meseret Zewdu, Bayew Kelkay Rade
BACKGROUND: Sexual and reproductive health rights (SRHRs) are integral elements of the rights of everyone to the highest attainable standard of physical and mental health, but they are the most underdeveloped and least understood sphere of rights, especially in Africa, including the country of Ethiopia. The implementation of women's SRHRs is essential for achieving gender equality and promoting women's rights. Husbands' knowledge and involvement play a significant role in improving women's practice of their SRHRs...
2024: Frontiers in Public Health
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