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JOURNAL ARTICLE
Ali E Kayalar, Eylem B K Ozlu, Mustafa U Etli, Arif T Calisaneller
BACKGROUND AND AIM: Chronic subdural hematoma (CSH) refers to intracranial hemorrhages frequently caused by minor head trauma and is mostly seen in middle and advanced age. One of the hypotheses regarding the development of CSH is that the inflammatory cascade plays a pivotal role in this process. MATERIALS AND METHODS: The inclusion criteria covered patients in all ages who were diagnosed as CSH by computed tomography and/or magnetic resonance imaging and treated by surgical intervention in our clinic between 2018 and 2020...
March 1, 2024: Neurology India
#2
JOURNAL ARTICLE
Aydan Arslan, Mustafa Güdük, Alp Dinçer
BACKGROUND: Incidental diagnosis of saccular aneurysms is more common with the advent of imaging techniques. Because of the severe morbidity and mortality that they can cause, treatment is chased for them, either microsurgical treatment or endovascular, even when they are diagnosed incidentally. Carotid cave aneurysms are rare, and they seem to have a more benign course compared to other intracranial aneurysms, probably related to the physical enveloping effect of the surrounding structures...
March 1, 2024: Neurology India
#3
JOURNAL ARTICLE
Yuwhan Chung, Sun Mo Nam, Sung Ho Lee, Kangmin Kim, Hyun-Seung Kang, Jeong Eun Kim, Won-Sang Cho
BACKGROUND AND OBJECTIVES: The role of bypass surgery in intracranial atherosclerotic steno-occlusive diseases (ICADs) remains controversial. We aimed to analyze the surgical outcomes of bypass surgery in patients with the ICADs in a single tertiary institution. METHODS: Among 1018 cases of low-flow bypass surgery between 2003 and 2022, 215 patients with the ICAD refractory to medical treatment were finally enrolled in this study. Clinical and radiological outcomes were retrospectively evaluated, with survival analyses...
May 1, 2024: Neurosurgery
#4
JOURNAL ARTICLE
Xinmin Deng, Wen Chang, Jingyi Zhu, Xiaofeng Lv, Rui Lai, Yu Cai, Shanshan Liu, Jingtao Liang
BACKGROUND: The association between hypothyroidism and stroke remains controversial and the association between hypothyroidism and stroke subtypes has not been satisfactorily researched. This study aimed to explore the causal effect of hypothyroidism on the risk of stroke and its subtypes by Mendelian randomization (MR) analysis. METHODS: Single nucleotide polymorphisms (SNPs) were selected from published genome-wide association studies (GWAS) meta-analysis as instrumental variables (IVs) for hypothyroidism...
April 28, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#5
JOURNAL ARTICLE
Răzvan Alexandru Radu, Vincent Costalat, Michele Romoli, Basel Musmar, James E Siegler, Sherief Ghozy, Jane Khalife, Hamza Salim, Hamza Shaikh, Nimer Adeeb, Hugo H Cuellar-Saenz, Ajith J Thomas, Ramanathan Kadirvel, Mohamad Abdalkader, Piers Klein, Thanh N Nguyen, Jeremy J Heit, Robert W Regenhardt, Joshua D Bernstock, Aman B Patel, James D Rabinov, Christopher J Stapleton, Nicole M Cancelliere, Thomas R Marotta, Vitor Mendes Pereira, Kareem El Naamani, Abdelaziz Amllay, Stavropoula I Tjoumakaris, Pascal Jabbour, Lukas Meyer, Jens Fiehler, Tobias D Faizy, Helena Guerreiro, Anne Dusart, Flavio Bellante, Géraud Forestier, Aymeric Rouchaud, Charbel Mounayer, Anna Luisa Kühn, Ajit S Puri, Christian Dyzmann, Peter T Kan, Marco Colasurdo, Gaultier Marnat, Jérôme Berge, Xavier Barreau, Igor Sibon, Simona Nedelcu, Nils Henninger, Takahiro Ota, Shogo Dofuku, Leonard L L Yeo, Benjamin Yq Tan, Anil Gopinathan, Juan Carlos Martinez-Gutierrez, Sergio Salazar-Marioni, Sunil Sheth, Leonardo Renieri, Carolina Capirossi, Ashkan Mowla, Lina M Chervak, Achala Vagal, Priyank Khandelwal, Arundhati Biswas, Frédéric Clarençon, Mahmoud Elhorany, Kevin Premat, Iacopo Valente, Alessandro Pedicelli, Andrea M Alexandre, João Pedro Filipe, Ricardo Varela, Miguel Quintero-Consuegra, Nestor R Gonzalez, Markus A Ymd, Jessica Jesser, Charlotte Weyland, Adrien Ter Schiphorst, Vivek Yedavalli, Pablo Harker, Yasmin Aziz, Benjamin Gory, Christian Paul Stracke, Constantin Hecker, Monika Killer-Oberpfalzer, Christoph J Griessenauer, Cheng-Yang Hsieh, David S Liebeskind, Illario Tancredi, Robert Fahed, Boris Lubicz, Muhammed Amir Essibayi, Amanda Baker, David Altschul, Luca Scarcia, Erwah Kalsoum, Adam A Dmytriw, Adrien Guenego
BACKGROUND: Optimal anesthetic strategy for the endovascular treatment of stroke is still under debate. Despite scarce data concerning anesthetic management for medium and distal vessel occlusions (MeVOs) some centers empirically support a general anesthesia (GA) strategy in these patients. METHODS: We conducted an international retrospective study of MeVO cases. A propensity score matching algorithm was used to mitigate potential differences across patients undergoing GA and conscious sedation (CS)...
April 30, 2024: Clinical Neuroradiology
#6
JOURNAL ARTICLE
Seo-Young Lee, Seung Jin Lee, Sam Su Kim, Hyo Sub Jun, Chungkun Oh, Chen Lin, Ji Hoon Phi
Unexplained neurological deterioration is occasionally observed in patients with traumatic brain injuries. We aimed to describe the clinical features of posttraumatic transient neurologic dysfunction and provide new insight into its pathophysiology. We retrospectively collected data from patients with focal neurologic deterioration of unknown origin during hospitalization for acute traumatic brain injury for 48 consecutive months. Brain imaging, including CT, diffusion weighted imaging and perfusion weighted imaging, and electroencephalography were conducted during the episodes...
April 30, 2024: Journal of Neurotrauma
#7
JOURNAL ARTICLE
Ethan A Winkler, Joshua S Catapano, Lea Scherschinski, Ashia M Hackett, Michael T Lawton
Posterior inferior cerebellar artery (PICA) aneurysms account for 0.3% of all intracranial aneurysms, and they commonly present with a complex fusiform morphology that necessitates unique bypass strategies.1-5 An adolescent boy with a familial predisposition to aneurysmal subarachnoid hemorrhage was identified as harboring a fusiform aneurysm of the right distal PICA, characterized by 2 outflow branches. Our recommended treatment strategy involved a right far lateral craniotomy, followed by P1 PICA reanastomosis and P2 PICA reimplantation...
April 30, 2024: Operative Neurosurgery (Hagerstown, Md.)
#8
JOURNAL ARTICLE
Sabrina L Zeller, Galadu Subah, Sauson Soldozy, Sima Vazquez, Fawaz Al-Mufti, Simon J Hanft
BACKGROUND AND OBJECTIVES: Postoperative intracranial hemorrhage (POH) is a serious neurosurgical complication occurring in approximately 1.4% of patients after intracranial tumor resection. The convention across the United States is to maintain an immediate postoperative systolic blood pressure (SBP) of < 140 mm Hg to minimize this risk; however, this SBP goal lacks support in the literature despite widespread adoption. This study aims to investigate the safety of SBP liberalization to 160 mm Hg in the immediate postoperative setting after intracranial tumor resection...
April 30, 2024: Operative Neurosurgery (Hagerstown, Md.)
#9
Kaoruko Iwasa, Shigeaki Nakazawa, Taigo Kato, Koji Hatano, Atsunari Kawashima, Shinichiro Fukuhara, Norio Nonomura
INTRODUCTION: Brain metastasis in renal cell carcinoma, which is reported in 10% of cases, leads to significant morbidity and mortality. Establishment of appropriate and safe treatment for brain metastasis renal cell carcinoma remains a pressing need. CASE PRESENTATION: A 56-year-old female patient, presenting with anorexia, headache, and occipital swelling, was subsequently diagnosed with clear cell renal cell carcinoma with multiple metastases, including intracranial and epicranial tumors...
May 2024: IJU case reports
#10
JOURNAL ARTICLE
Xinbo Li, Chengwei Zhang, Jiale Wang, Chengxing Ye, Jiaqian Zhu, Qichuan Zhuge
BACKGROUND: Postoperative pneumonia (POP) is one of the primary complications after aneurysmal subarachnoid hemorrhage (aSAH) and is associated with postoperative mortality, extended hospital stay, and increased medical fee. Early identification of pneumonia and more aggressive treatment can improve patient outcomes. We aimed to develop a model to predict POP in aSAH patients using machine learning (ML) methods. METHODS: This internal cohort study included 706 patients with aSAH undergoing intracranial aneurysm embolization or aneurysm clipping...
2024: Frontiers in Neurology
#11
JOURNAL ARTICLE
Liang Li, Zhihui Liang, Cong Lin, Bao Cui, Qiong Jia
BACKGROUND: Mechanical thrombectomy (MT) is one of the effective treatment methods for acute ischemic stroke (AIS), which requires a period of dual antiplatelet therapy (DAPT) after endovascular treatment. This study aimed to compare the efficacy and safety of 3-month DAPT and 1-month DAPT in AIS patients receiving MT through a retrospective study. METHODS: AIS patients who received MT from May 2018 to March 2023 were grouped into a 1-month group (1-M group) and a 3-month group (3-M group) according to the duration of DAPT after MT...
2024: Frontiers in Neurology
#12
JOURNAL ARTICLE
Susan Rowell, Eric N Meier, Tatiana Hoyos Gomez, Michael Fleming, Jon Jui, Laurie Morrison, Eileen Bulger, George Sopko, Myron Weisfeldt, Jim Christenson, Pat Klotz, Jason McMullan, Jeannie Callum, Kellie Sheehan, Brian Tibbs, Tom Aufderheide, Bryan Cotton, Rajesh Gandhi, Ahamed Idris, Ralph J Frascone, Michael Ferrara, Neil Richmond, Delores Kannas, Rob Schlamp, Bryce Robinson, David Dries, John Tallon, Audrey Hendrickson, Mark Gamber, John Garrett, Robert Simonson, W Ian McKinley, Martin Schreiber
BACKGROUND: In the Prehospital Tranexamic Acid (TXA) for TBI Trial, TXA administered within two hours of injury in the out-of-hospital setting did not reduce mortality in all patients with moderate/severe traumatic brain injury (TBI). We examined the association between TXA dosing arms, neurologic outcome, and mortality in patients with intracranial hemorrhage (ICH) on computed tomography (CT). METHODS: This was a secondary analysis of the Prehospital Tranexamic Acid for TBI Trial (ClinicalTrials...
April 30, 2024: Journal of Trauma and Acute Care Surgery
#13
JOURNAL ARTICLE
Huong Bich Thi Nguyen, Trung Quoc Nguyen, Vu Thanh Tran, Tra Son Vu Le, Anh Tuan Le Truong, Binh Nguyen Pham, Sang Hung Nguyen, Anit Kiran Behera, Thanh Thien Nguyen, Thang Ba Nguyen, Thanh N Nguyen, Thang Huy Nguyen
Introduction Intracranial atherosclerotic disease (ICAD) has been identified as a major cause of acute basilar artery occlusion (BAO).This study compared the characteristics and treatment outcomes in acute BAO patients with and without ICAD. Methods A prospective cohort study was conducted at 115 People's Hospital, Ho Chi Minh city, Vietnam from August 2021 to June 2023. Patients with acute BAO who underwent endovascular treatment within 24 hours from symptom onset were included (thrombectomy alone or bridging with intravenous alteplase)...
April 29, 2024: Cerebrovascular Diseases
#14
MULTICENTER STUDY
Alicia Pérez-Blanco, María Acevedo, María Padilla, Aroa Gómez, Luis Zapata, María Barber, Adolfo Martínez, Verónica Calleja, María C Rivero, Esperanza Fernández, Julio Velasco, Eva M Flores, Brígida Quindós, Sergio T Rodríguez, Beatriz Virgós, Juan C Robles, Agustín C Nebra, José Moya, Josep Trenado, Nieves García, Ana Vallejo, Eugenio Herrero, Álvaro García, Maria L Rodríguez, Fernando García, Ramón Lara, Lucas Lage, Francisco J Gil, Francisco J Guerrero, Ángela Meilán, Nayade Del Prado, Cristina Fernández, Elisabeth Coll, Beatriz Domínguez-Gil
Intensive Care to facilitate Organ Donation (ICOD) consists of the initiation or continuation of intensive care measures in patients with a devastating brain injury (DBI) in whom curative treatment is deemed futile and death by neurological criteria (DNC) is foreseen, to incorporate organ donation into their end-of-life plans. In this study we evaluate the outcomes of patients subject to ICOD and identify radiological and clinical factors associated with progression to DNC. In this first prospective multicenter study we tested by multivariate regression the association of clinical and radiological severity features with progression to DNC...
2024: Transplant International
#15
Sofia Kanna, George Mixides, Costas Michaelides
This case report demonstrates the difficulty of diagnosing and managing the pharyngeal-cervical-brachial (PCB) variant of Guillain-Barré syndrome (GBS), as well as the rare complication of intracerebral hemorrhage (ICH). A male patient in his mid-60s, presented with bilateral upper limb weakness, bilateral ptosis, and bulbar symptoms. The clinical presentation combined with paraclinical findings supported the diagnosis of PCB. During the course of PCB, the patient required tracheostomy and gastrostomy due to the worsening of his symptoms...
March 2024: Curēus
#16
JOURNAL ARTICLE
Manisha Koneru, Hamza A Shaikh, Daniel A Tonetti, James E Siegler, Jane Khalife, Ajith J Thomas, Tudor G Jovin, Corey M Mossop
Objective Identifying ischemic stroke is a diagnostic challenge in the trauma subpopulation. We describe our early experience with artificial intelligence-assisted image analysis software for automatically identifying acute ischemic stroke in trauma patients. Methods Patients were retrospectively screened for (i) admission to the trauma service at a level one trauma center between 2020 and 2022, (ii) radiologist-confirmed intracranial occlusion, (iii) occlusion identified on computed tomography angiography performed within 24 hours of admission, (iv) no intracranial hemorrhage, and (v) contemporaneous analysis with the large vessel occlusion (LVO) detection program...
March 2024: Curēus
#17
Moustafa Elsebey, Vidya Nandlal, Florentina Litra
Newborns are prone to hemorrhagic disease due to vitamin K deficiency for multiple reasons, including vitamin K absence in breast milk and formula preparation, sterile gut with limited absorption, and lack of placental transfer. Despite the importance of vitamin K administration at birth in preventing hemorrhagic disease in infants, some parents still refuse administration to their newborns. One of the unexpected but preventable reasons is the language barrier related to special dialects, resulting in misunderstanding the benefits of vitamin K administration and complications related to vitamin K deficiency...
March 2024: Curēus
#18
Mark Johnson
In acute care environments, accurately assessing complications of intracranial pathology can be challenging. Ocular complications in acute intracranial disease are not consistently evaluated despite their high morbidity. We report on a case of monocular diplopia in a 63-year-old man with subacute traumatic brain injury with localized subarachnoid hemorrhage. Ocular point of care ultrasound (POCUS) identified features of vitreous hemorrhage in one globe, leading to a diagnosis of Terson syndrome and a timely referral to ophthalmology...
2024: POCUS J
#19
JOURNAL ARTICLE
Manxiong Cao, Jiaqiong Hong, Dongqing Zhang, Feiheng Chen, Yongzhong Su
In acute promyelocytic leukemia (APL), hemorrhage, particularly intracranial hemorrhage, is the most common cause of early death. A central venous catheter (CVC) may provide a greater guarantee of safety and comfort to APL patients. However, CVCs have seldom been attempted in APL patients during induction therapy because of concerns about increasing the risk of hemorrhagic complications after this invasive procedure. To evaluate the hemorrhagic risk after CVC placement in APL patients during induction therapy, we retrospectively analyzed 95 newly diagnosed patients with APL from January 2010 to December 2022...
2024: Frontiers in Oncology
#20
JOURNAL ARTICLE
Haroon Ahmed, Nicola Reeve, Daniel Farewell, Fergus Hamilton, Mark Ponsford, Julia Hippisley-Cox, Simon Noble
PURPOSE: Incidence of bleeding amongst warfarin and direct oral anticoagulant (DOAC) users is greater following a respiratory tract infection (RTI). It is unclear whether immediate antibiotics modify this association. We estimated the risk of bleeding amongst warfarin and DOAC users with RTI by antibiotic treatment. METHODS: This retrospective cohort study used data from the Clinical Practice Research Datalink (CPRD) GOLD for adults in England prescribed warfarin or a DOAC, who sought primary care for an RTI between 1st January 2011 and 31st December 2019...
May 2024: Pharmacoepidemiology and Drug Safety
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