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JOURNAL ARTICLE
Francisco J Pastor-Pérez, Iris P Garrido-Bravo, Pablo Peñafiel-Verdú, Noelia Fernández-Villa, Sergio Manzano-Fernández, María José Oliva-Sandoval, María Teresa Pérez-Martínez, César Caro-Martínez, Álvaro Hernández-Vicente, Domingo A Pascual-Figal
Introduction and objectives Cardiac resynchronization therapy (CRT) is an effective treatment for patients with nonischemic dilated cardiomyopathy associated with left bundle branch block (LBBB). In these patients, the device can normalize left ventricular ejection fraction (LVEF). Nevertheless, it remains unclear whether CRT responders still require neurohormonal blockers. The aim of this study is to determine the long-term safety of withdrawing drug therapy in these patients. Methods The REMOVE trial (NCT05151861) is a prospective, multicenter, open-label and randomized 1:1 study designed to assess the effect of withdrawing neurohormonal blockers in patients with nonischemic dilated cardiomyopathy associated with left bundle branch block who recovered LVEF after CRT...
May 1, 2024: Revista Española de Cardiología
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JOURNAL ARTICLE
Giovanni Morani, Bruna Bolzan, Antonio Pepe, Giampaolo Berton, Mattia Strazzanti, Flavio Luciano Ribichini
BACKGROUND: Axillary vein puncture (AVP) is a valid alternative to Subclavan vein puncture for leads insertion in cardiac implantable electronic device implantation, that may reduce acute and delayed complications. Very few data are available about ICD recipients. A simplified AVP technique is described. METHODS: All the patients who consecutively underwent "de novo" ICD implantation, from March 2006 to December 2020 at the University of Verona, were considered...
April 30, 2024: International Journal of Cardiology
#3
JOURNAL ARTICLE
Hongjin Si, Zhuo He, Saurabh Malhotra, Xinwei Zhang, Fengwei Zou, Siyuan Xue, Zhiyong Qian, Yao Wang, Xiaofeng Hou, Weihua Zhou, Jiangang Zou
BACKGROUND: The segment of the latest mechanical contraction (LMC) does not always overlap with the site of the latest electrical activation (LEA). By integrating both mechanical and electrical dyssynchrony, this proof-of-concept study aimed to propose a new method for recommending left ventricular (LV) lead placements, with the goal of enhancing response to cardiac resynchronization therapy (CRT). METHODS: The LMC segment was determined by single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) phase analysis...
April 30, 2024: Journal of Nuclear Cardiology
#4
JOURNAL ARTICLE
Javier De Juan Bagudá, Rocío Cózar León, Juan J Gavira Gómez, Marta Pachón, Josebe Goirigolzarri Artaza, Virgilio Martínez Mateo, Vanessa Escolar Pérez, Ángel Manuel Iniesta Manjavacas, Nuria Rivas Gándara, Jesús Álvarez-García, Jesús Gabriel Sánchez Ramos, Cristina Aguilera Agudo, José Manuel Rubín López, Alfonso Macías Gallego, Silvia López Fernández, Luis González Torres, Juan Gabriel Martínez, Natalia Marrero Negrín, Javier Ramos Maqueda, Mercedes Cabrera Ramos, José María Medina Gil, Carlos De Diego Rus, Francisco José Bermúdez Jiménez, Inés Madrazo, Beatriz Díaz Molina, Marta Cobo Marcos, Ana Delia Ruiz Duthil, David Cordero, Ana Belén Méndez Fernández, Laura Peña Conde, María F Arcocha Torres, Nicasio Pérez Castellano, Miguel A Arias, Ignacio García Bolao, Ernesto Díaz Infante, Monica Campari, Fernando Arribas Ynsaurriaga, Juan F Delgado Jiménez, Sergio Valsecchi, Rafael Salguero Bodes
INTRODUCTION AND OBJECTIVES: The multiparametric implantable cardioverter-defibrillator HeartLogic index has proven to be a sensitive and timely predictor of impending heart failure (HF) decompensation. We evaluated the impact of a standardized follow-up protocol implemented by nursing staff and based on remote management of alerts. METHODS: The algorithm was activated in HF patients at 19 Spanish centers. Transmitted data were analyzed remotely, and patients were contacted by telephone if alerts were issued...
April 30, 2024: Revista Española de Cardiología
#5
JOURNAL ARTICLE
Johannes Kirchner, Muhammed Gerçek, Vanessa Sciacca, Jan-Christian Reil, Denise Guckel, Max Potratz, Hazem Omran, Kai Friedrichs, Thomas Eitz, Sabine Bleiziffer, Rene Schramm, Guram Imnadze, Christian Sohns, Jan Gummert, Volker Rudolph, Tanja K Rudolph, Philipp Sommer, Thomas Fink
BACKGROUND: Permanent pacemaker implantation (PMI) is associated with increased morbidity after transcatheter aortic valve replacement (TAVR). Cardiac resynchronization-therapy (CRT) is recommended for patients if left ventricular ejection fraction (LVEF) is ≤ 40% and ventricular pacing is expected in favor to sole right ventricular (RV) pacing. Meanwhile, LVEF may recover after TAVR in patients with aortic valve disease and the benefit of CRT is unknown. OBJECTIVE: To analyze the impact of CRT implantation as compared to RV pacing after TAVR...
May 2, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
#6
JOURNAL ARTICLE
Weiwei Zhang, Xueying Chen, Jingjuan Huang, Xingyu Zhang, Yiding Qi, Junxiao Wang, Xiaohong Zhou, Yangang Su, Xumin Hou, Ruogu Li
No abstract text is available yet for this article.
April 29, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#7
JOURNAL ARTICLE
Erik Lipsic, Fenna Daniels, Hessel F Groenveld, Michiel Rienstra, Alexander H Maass
Due to increasing use of cardiac implantable electronic devices (CIEDs) with one or more intracardiac electrodes, the rate of lead failure is increasing. Moreover, an upgrade of the CIED is frequently indicated for cardiac resynchronization therapy or other reasons. Both these situations require a new intervention, preferably using the ipsilateral venous access. However, venous obstruction after CIED insertion occurs in 10-20% of patients and poses a major obstacle for implantation of additional leads. Possible solutions include lead extraction, contralateral lead insertion, and venoplasty...
April 29, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#8
EDITORIAL
Akash Batta, Juniali Hatwal
The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacing-induced cardiomyopathy. Until recently, biventricular pacing (BiVP) was the only modality which could mitigate or prevent pacing induced dysfunction. Further, BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes. However, the high non-response rate of around 20%-30% remains a major limitation. This non-response has been largely attributable to the direct non-physiological stimulation of the left ventricular myocardium bypassing the conduction system...
April 26, 2024: World Journal of Cardiology
#9
JOURNAL ARTICLE
Nika Kuridze, Mikheil Tsverava, Tengiz Verulava
INTRODUCTION: Assessing the quality of life serves as a crucial metric during various therapeutic or surgical procedures. The rise in cardiac electronic device implantations in recent years underscores the significance of evaluating the quality of life among such patients. MATERIALS AND METHODS: We conducted a study focusing on the quality of life of 438 patients with cardiac implantable electronic devices (cardiac pacemakers, cardioverter-defibrillators, cardiac resynchronization therapy devices)...
March 2024: Curēus
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JOURNAL ARTICLE
Yuichiro Miyazaki, Kohei Ishibashi, Nobuhiko Ueda, Satoshi Oka, Akinori Wakamiya, Keiko Shimamoto, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takeshi Aiba, Kengo Kusano
BACKGROUND: The adaptive cardiac resynchronization therapy (aCRT) algorithm enables synchronized left ventricular pacing (sLVP) to achieve fusion with intrinsic right ventricular activation. Although sLVP presents benefits over biventricular pacing, the adequate sLVP rate for better clinical outcomes remains unclear. We aimed to assess the association between sLVP rates and clinical outcomes. METHODS: Our study cohort included 271 consecutive patients, who underwent CRT implantation between April 2016 and August 2021...
April 26, 2024: Journal of Cardiology
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JOURNAL ARTICLE
Hao Huang, Bingqi Fu, Tianxin Long, Yu Yu, Sijing Cheng, Min Gu, Chi Cai, Xuhua Chen, Hongxia Niu, Wei Hua
PURPOSE: Geriatric Nutritional Risk Index (GNRI) is a simple tool for assessing the nutritional status of the aging population. This study aims to explore the clinical implication of GNRI on treatment response and long-term clinical outcomes in heart failure (HF) patients receiving cardiac resynchronization therapy (CRT). METHODS: Patients who underwent CRT implantation or upgrade at our hospital were retrospectively included. The association of GNRI and its tertiles with the echocardiographic response, all-cause mortality or heart transplantation, and the first hospitalization due to HF were investigated...
April 24, 2024: International Journal of Cardiology
#12
REVIEW
Juan Carlos Diaz, Mohamed Gabr, Usha B Tedrow, Mauricio Duque, Julian Aristizabal, Jorge Marin, Cesar Niño, Oriana Bastidas, Bruce A Koplan, Carolina Hoyos, Carlos D Matos, Daniela Hincapie, Kevin Pacheco-Barrios, Isabella Alviz, Nathaniel A Steiger, Sunil Kapur, Thomas M Tadros, Paul C Zei, William H Sauer, Jorge E Romero
BACKGROUND: Left bundle branch area pacing (LBBAP) has emerged as a physiological alternative pacing strategy to biventricular pacing (BIVP) in cardiac resynchronization therapy (CRT). We aimed to assess the impact of LBBAP vs. BIVP on all-cause mortality and heart failure (HF)-related hospitalization in patients undergoing CRT. METHODS: Studies comparing LBBAP and BIVP for CRT in patients with HF with reduced left ventricular ejection fraction (LVEF) were included...
April 26, 2024: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
#13
REVIEW
Antonio Scarà, Zefferino Palamà, Antonio Gianluca Robles, Lorenzo-Lupo Dei, Alessio Borrelli, Federico Zanin, Leonardo Pignalosa, Silvio Romano, Luigi Sciarra
Heart failure (HF) represents a significant global health challenge that is still responsible for increasing morbidity and mortality despite advancements in pharmacological treatments. This review investigates the effectiveness of non-pharmacological interventions in the management of HF, examining lifestyle measures, physical activity, and the role of some electrical therapies such as catheter ablation, cardiac resynchronization therapy (CRT), and cardiac contractility modulation (CCM). Structured exercise training is a cornerstone in this field, demonstrating terrific improvements in functional status, quality of life, and mortality risk reduction, particularly in patients with HF with reduced ejection fraction (HFrEF)...
April 17, 2024: Journal of Cardiovascular Development and Disease
#14
JOURNAL ARTICLE
Matteo Baroni, Alberto Preda, Marco Carbonaro, Matteo Fortuna, Fabrizio Guarracini, Lorenzo Gigli, Patrizio Mazzone
No abstract text is available yet for this article.
April 26, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#15
JOURNAL ARTICLE
Graham H Bevan, Jonathan Buber
No abstract text is available yet for this article.
April 25, 2024: Heart
#16
JOURNAL ARTICLE
Yuichiro Miyazaki, Kohei Ishibashi, Nobuhiko Ueda, Toshihiro Nakamura, Satoshi Oka, Akinori Wakamiya, Kenzaburo Nakajima, Mitsuru Wada, Takeshi Aiba, Kengo Kusano
The adaptive cardiac resynchronization therapy (CRT) algorithm provides synchronized left ventricular pacing (sLVP). However, ensuring a high sLVP rate is challenging. We assessed the association between the sLVP rate and pacing sites in the right atrium. We evaluated 71 patients who underwent CRT and in whom the adaptive CRT algorithm was applied (53 men; mean age, 66 ± 14 years; median follow-up period, 301 days; IQR: 212-596 days). The atrial pacing leads were positioned in the right atrial (RA) septum in 17 patients (septal group) and in the RA appendage in 54 patients (RA appendage group), with significantly higher sLVP rates in the septal group compared with the RA appendage group (81% ± 30% vs 63% ± 37%; P = 0...
April 2024: JACC Asia
#17
JOURNAL ARTICLE
Auke A A Verstappen, Rick Hautvast, Pavel Jurak, Frank A Bracke, Leonard M Rademakers
BACKGROUND: Left bundle branch pacing (LBBP) is a novel physiological pacing technique which may serve as an alternative to cardiac resynchronization therapy (CRT) by biventricular pacing (BVP). This study assessed ventricular activation patterns and echocardiographic and clinical outcomes of LBBP and compared this to BVP. METHODS: Fifty consecutive patients underwent LBBP or BVP for CRT. Ventricular activation mapping was obtained by ultra-high-frequency ECG (UHF-ECG)...
April 22, 2024: Indian Pacing and Electrophysiology Journal
#18
JOURNAL ARTICLE
Stefan D Anker, Tim Friede, Ralph Stephan von Bardeleben, Javed Butler, Kaneez Fatima, Monika Diek, Jutta Heinrich, Gerd Hasenfuß, Wolfgang Schillinger, Piotr Ponikowski
AIMS: The safety and effectiveness of the MitraClip device to treat functional mitral regurgitation (FMR) has been tested in previous clinical trials yielding somewhat heterogeneous results in heart failure (HF) patients. Over time, the MitraClip device system has been modified and clinical practice evolved to consider also less severely diseased HF patients with FMR for this therapeutic option. The RESHAPE-HF2 trial aims to assess the safety and effectiveness of the MitraClip device system on top of medical therapy considered optimal in the treatment of clinically significant FMR in symptomatic patients with chronic HF...
April 23, 2024: European Journal of Heart Failure
#19
JOURNAL ARTICLE
Brian Wisnoskey, Niraj Varma
No abstract text is available yet for this article.
March 30, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
#20
JOURNAL ARTICLE
Jonathan J H Bray, Marco Coronelli, Sam G C Scott, John A Henry, Liam S Couch, Mahmood Ahmad, Julian Ormerod, James Gamble, Timothy R Betts, Andrew Lewis, Oliver J Rider, Peregrine G Green, Neil Herring
AIMS: The trials upon which recommendations for the use of cardiac resynchronization therapy (CRT) in heart failure used optimal medical therapy (OMT) before sodium-glucose co-transporter 2 inhibitors (SGLT2i). Moreover, the SGLT2i heart failure trials included only a small proportion of participants with CRT, and therefore, it remains uncertain whether SGLT2i should be considered part of OMT prior to CRT. METHODS AND RESULTS: We compared electrocardiogram (ECG) and echocardiographic responses to CRT as well as hospitalization and mortality rates in consecutive patients undergoing implantation at a large tertiary centre between January 2019 to June 2022 with and without SGLT2i treatment...
April 22, 2024: ESC Heart Failure
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