Maria Kruglova, Nikolai Nikitin, Ekaterina Evtushenko, Irina Matveeva, Aleksandr Mazurov, Igor Pavlenko, Vera Popova, Olesya Bogomolova, Stepan Vasilyev, Evgeniya Markova, Yuri Fedorov
Chlamydia abortus is the etiological agent of abortion and fetal loss in sheep, goats and bovine cattle in many countries. Even though commercially available vaccines can reduce the incidence in sheep, the development of new, safe, and effective vaccines remains high on the agenda. In this study, an evaluation was made of the efficacy of a vaccine candidate, an inactivated antigen based on the extract of outer membrane proteins of a C. abortus strain known as Chlamydia VNITIBP-21 , in combination with recombinant flagellin as an adjuvant...
March 24, 2024: Pathogens