Thomas H Dohlman, Rohan Bir Singh, Francisco Amparo, Tatiana Carreno-Galeano, Mohammad Dastjerdi, Giulia Coco, Antonio Di Zazzo, Hasanain Shikari, Ujwala Saboo, Kimberly Sippel, Jessica Ciralsky, Sonia H Yoo, Matheus Sticca, Tais H Wakamatsu, Somasheila Murthy, Pedram Hamrah, Ula Jurkunas, Joseph B Ciolino, Hajirah Saeed, Jose A P Gomes, Victor L Perez, Jia Yin, Reza Dana
PURPOSE: To assess the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation. DESIGN: Secondary analysis of prospective, randomized, double-blind, placebo-controlled multicentric clinical trial. PARTICIPANTS: The study includes patients aged > 18 years who underwent high-risk penetrating keratoplasty, which was defined as corneal vascularization in ≥ 1 quadrants of the corneal graft and host bed, excluding the limbus...
2024: Ophthalmol Sci