Jiang Wang, Shun Xiong, Xiangwei Hao, Yang Gao, Fei Xia, Haiyuan Liao, Jiayi Zou, Guoning Huang, Wei Han
PURPOSE: Zygotes with 2.1 pronuclei (2.1PN) present with two normal-sized pronuclei, and an additional smaller pronucleus, that is approximately smaller than two thirds the size of a normal pronucleus. It remains unclear whether the additional pronucleus causes embryonic chromosome abnormalities. In the majority of cases, in vitro fertilization (IVF) clinics discarded 2.1PN zygotes. Thus, the present study aimed to evaluate the developmental potential and value of 2.1PN zygotes. METHODS: 2...
April 13, 2024: Journal of Assisted Reproduction and Genetics