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REVIEW
Mahi Basra, Hemangi Patel, Alexandria Sobczak, Jordan Ditchek, Alejandro Biglione, Marc M Kesselman, Alessandra Posey
Spondyloarthropathy (SpA) is one of the most common causes of low back pain. It is caused by inflammatory arthritis in the spine, manifesting in various forms such as psoriatic arthritis (PsA), ankylosing spondylitis (AS), and sacroiliitis. A comprehensive systematic literature search was done to evaluate and compare MRI, CT, single-photon emission CT, PET, ultrasound (US) imaging, low-dose CT, and diffusion-weighted imaging (DWI) techniques in assessing SpAs. The search strategy was constructed by an analysis of key terms from relevant articles in MEDLINE ProQuest, Embase, and PubMed...
March 2024: Curēus
#2
REVIEW
Palapun Waitayangkoon, Pablo Weilg-Espejo, Eugene Y Kissin
Ultrasound (US) can visualize the periosteal changes in the early stage compared to radiography. In this review, we studied periosteal manifestations on US and assessed their diagnostic utility for osteomyelitis (OM) and arthritis. We included articles that studied ultrasonographic findings of periosteal changes in OM and arthropathies with aims to systematically review periosteal manifestations of each condition and summarize diagnostic values of each finding. A total of 13 articles were included in the systematic review...
2024: Journal of Medical Ultrasound
#3
Ikwinder Preet Kaur, Gurjit Kaeley
Bicipitoradial bursitis is an unusual cause of cubital fossa pain in PsA patients. Bedside Ultrasound is a valuable tool to correlate the source of pain in rheumatic and musculoskeletal diseases.
April 2024: Clinical Case Reports
#4
JOURNAL ARTICLE
Ines Mahmoud, Leila Rouached, Safa Rahmouni, Siwar Ben Dhia, Aicha Ben Tekaya, Selma Bouden, Rawdha Tekaya, Wafa Hamdi, Olfa Saidane, Leila Abdelmoula
OBJECTIVES: Nail unit is one of the targets of ultrasound (US) assessment. We aimed to compare ultrasound parameters of clinically normal nail unit in psoriatic arthritis (PsA) patients with healthy controls (HC) and evaluate their correlations with disease activity. METHODS: This was a cross-sectional study including patients with PsA and matched HC. Tender (TJC) and swollen joint count (SJC), Psoriasis Area and Severity Index (PASI), and Disease Activity in Psoriatic Arthritis (DAPSA) were collected in PsA patients...
April 18, 2024: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
#5
JOURNAL ARTICLE
Anber Ancel Tanaka, Betina Werner, Annelise Correa Bueno Bragatto, Thelma Larocca Skare, Bárbara Stadler
BACKGROUND: Nail involvement is frequent in patients with psoriasis (Pso) and psoriatic arthritis (PsA) and there is a relationship between nail involvement and inflammation of the enthesis. The main objective of the present study is to describe the ultrasound findings and clinical characteristics of nails from patients with psoriasis and psoriatic arthritis with and without nail dystrophy. METHODS: A cross-sectional study including consecutive patients with PsO and PsA was carried out...
April 11, 2024: Advances in Rheumatology
#6
JOURNAL ARTICLE
Dario Graceffa, Arianna Zangrilli, Giacomo Caldarola, Viviana Lora, Diego Orsini, Gala Moretta, Gianluca Pagnanelli, Alessia Provini, Cinzia Masini, Mauro Bavetta, Domenico Giordano, Antonio Richetta, Ersilla Tolino, Luca Bianchi, Ketty Peris, Francesca Sperati, Claudio Bonifati
BACKGROUND: IL-23 inhibitors were recently approved for the treatment of skin psoriasis and psoriatic arthritis (PsA). Risankizumab, a humanized monoclonal antibody that specifically binds the p19 subunit of IL-23, has proven effective on PsA in two randomized controlled trials. To date, only a few real-world data are available on this topic. METHODS: Our study aimed to prospectively evaluate the effectiveness of risankizumab in patients with PsA in a real-world setting...
April 7, 2024: International Journal of Dermatology
#7
JOURNAL ARTICLE
Arwa S Amer, Ahmed Y Al Shambaky, Seham G Ameen, Amira Khalil Sobih
BACKGROUND: Enthesopathy is considered a crucial aspect of assessment and outcome in psoriatic arthritis (PsA). Musculoskeletal ultrasound (MSUS) is a critical tool for accurately detecting enthesitis. Recent research focuses on identifying simple biomarkers for detecting and monitoring psoriatic enthesopathy. Red cell distribution width (RDW), mean platelet volume (MPV), and neutrophil/lymphocyte ratio (NLR) are components of a complete blood count (CBC) and are reliable bio-inflammatory markers in various rheumatic diseases...
April 8, 2024: Clinical Rheumatology
#8
JOURNAL ARTICLE
Or Hen, Andrea Di Matteo, Sayam R Dubash, Gabriele De Marco, Ai Lyn Tan, Paul Emery, Richard J Wakefield, Dennis G McGonagle, Philip Helliwell, Helena Marzo-Ortega
AIMS: To investigate the prevalence and distribution of bone erosions in an early psoriatic arthritis (PsA) population using conventional radiography (CR) and to explore the agreement between CR and ultrasound (US) detected bone erosions. METHODS: Newly diagnosed, treatment naïve PsA patients fulfilling the ClASsification for Psoriatic Arthritis (CASPAR) classification criteria of ≤5 years symptom duration were recruited as part of the Leeds Spondyloarthropathy Register for Research and Observation and underwent CR and US examination of hands and feet...
April 5, 2024: RMD Open
#9
JOURNAL ARTICLE
Zouhour Gassara, Afef Feki, Zina Hakim, Samar Ben Djmeaa, Cyrine Abid, Mohamed Hedi Kallel, Hela Fourati, Sofien Baklouti
BACKGROUND: The purpose of this study was to evaluate the prevalence of foot involvement in psoriatic arthritis and to describe its different clinical and radiological features. PATIENTS AND METHODS: We conducted a cross sectional study including 40 patients with psoriatic arthritis over a period of 12 months. Anamnesis, clinical examination of feet, podoscopic examination, X-rays of feet and heels, and ultrasound in B mode and power Doppler mode were done for each patient...
March 21, 2024: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
#10
JOURNAL ARTICLE
Esperanza Naredo, Maria Antonietta D'Agostino, Lene Terslev, Carlos Pineda, M Isabel Miguel, Joan Blasi, George A Bruyn, Marion C Kortekaas, Peter Mandl, Rodina Nestorova, Marcin Szkudlarek, Plamen Todorov, Violeta Vlad, Priscilla Wong, Catherine Bakewell, Emilio Filippucci, Alen Zabotti, Mihaela Micu, Florentin Vreju, Mohamed Mortada, José Alexandre Mendonça, Carlos A Guillen-Astete, Otto Olivas-Vergara, Annamaria Iagnocco, Petra Hanova, Ilaria Tinazzi, Peter V Balint, Sibel Zehra Aydin, David Kane, Helen Keen, Gurjit S Kaeley, Ingrid Möller
OBJECTIVES: The main objective was to generate a GLobal OMERACT Ultrasound DActylitis Score (GLOUDAS) in psoriatic arthritis and to test its reliability. To this end, we assessed the validity, feasibility and applicability of ultrasound assessment of finger entheses to incorporate them into the scoring system. METHODS: The study consisted of a stepwise process. First, in cadaveric specimens, we identified enthesis sites of the fingers by ultrasound and gross anatomy, and then verified presence of entheseal tissue in histological samples...
April 4, 2024: Annals of the Rheumatic Diseases
#11
REVIEW
A L Ribeiro, L Eder
PURPOSE OF REVIEW: This review summarizes the literature about the transition from psoriasis to psoriatic arthritis (PsA), focusing on musculoskeletal ultrasound (MSUS) for detecting subclinical inflammation and its role in diagnosis and triage of high-risk patients. RECENT FINDINGS: MSUS effectively detects subclinical musculoskeletal inflammation in patients with psoriasis; however, some of these lesions are non-specific and can be found in healthy individuals...
March 21, 2024: Current Rheumatology Reports
#12
REVIEW
Daniel Octavian Costache, Horia Blejan, Damian Lucian Cojocaru, Georgiana Alexandra Ioniță, Marcela Poenaru, Maria Magdalena Constantin, Andrei Cătălin Costache, Constantin Căruntu, Daniel Vasile Balaban, Raluca Simona Costache
Psoriasis is a chronic, immune-mediated, inflammatory disease that has a major impact on patients' quality of life. Common psoriasis-associated comorbidities include cardiovascular diseases, psoriatic arthritis, inflammatory bowel syndromes, type-2 diabetes, and metabolic syndrome. Nonalcoholic fatty liver disease (NAFLD) is affecting a substantial portion of the population and is closely linked with psoriasis. The interplay involves low-grade chronic inflammation, insulin resistance, and genetic factors. The review presents the pathophysiological connections between psoriasis and nonalcoholic fatty liver disease, emphasizing the role of cytokines, adipokines, and inflammatory cascades...
February 24, 2024: International Journal of Molecular Sciences
#13
JOURNAL ARTICLE
Rubén Queiro, Estefanía Pardo
No abstract text is available yet for this article.
March 11, 2024: Rheumatology
#14
JOURNAL ARTICLE
Andrea Di Matteo, Gianluca Smerilli, Stefano Di Donato, An Ran Liu, Andrea Becciolini, Federica Camarda, Tomas Cazenave, Edoardo Cipolletta, Davide Corradini, Juan José de Agustín, Giulia Maria Destro Castaniti, Eleonora Di Donato, Luca Di Geso, Emine Duran, Bayram Farisogullari, Marco Fornaro, Francesca Francioso, Pamela Giorgis, Amelia Granel, Cristina Hernández-Díaz, Rudolf Horvath, Jana Hurnakova, Diogo Jesus, Omer Karadag, Ling Li, Josefina Marin, María Victoria Martire, Xabier Michelena, Erica Moscioni, Laura Muntean, Matteo Piga, Marcos Rosemffet, João Rovisco, Didem Sahin, Fausto Salaffi, Liliana Saraiva, Crescenzio Scioscia, Maria-Magdalena Tamas, Shun Tanimura, Aliki Venetsanopoulou, Lucio Ventura-Rios, Orlando Villota, Catalina Villota-Eraso, Paraskevi V Voulgari, Gentiana Vukatana, Johana Zacariaz Hereter, Helena Marzo-Ortega, Walter Grassi, Emilio Filippucci
OBJECTIVES: To assess, in spondyloarthritis (SpA), the discriminative value of the Outcome Measures in Rheumatology (OMERACT) ultrasound lesions of enthesitis and their associations with clinical features in this population. METHODS: In this multicentre study involving 20 rheumatology centres, clinical and ultrasound examinations of the lower limb large entheses were performed in 413 patients with SpA (axial SpA and psoriatic arthritis) and 282 disease controls (osteoarthritis and fibromyalgia)...
March 5, 2024: Annals of the Rheumatic Diseases
#15
JOURNAL ARTICLE
Bilal Kulaksız, Deniz Palamar, Tugce Ozekli Misirlioglu, Kenan Akgun, Rana Terlemez
OBJECTIVES: This study aimed to evaluate the nail units of patients with axial spondyloarthritis (ax-SpA) using ultrasound and to identify any subclinical changes. We also aimed to examine the relationship between clinical enthesitis scores and nail involvement in patients with ax-SpA. METHODS: The study included 40 patients with ax-Spa, 40 patients with psoriatic arthritis (PsA), and 40 healthy controls. The thickness of the nail plates, morphological changes, the thickness of the proximal nail units, the thickness of the nail beds, and power Doppler signal intensities were evaluated and compared...
February 7, 2024: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
#16
Mihaela Agache, Claudiu C Popescu, Luminita Enache, Bianca M Dumitrescu, Catalin Codreanu
In the original publication [...].
January 16, 2024: Diagnostics
#17
JOURNAL ARTICLE
Ana Belén Azuaga, Andrea Cuervo, Raquel Celis, Beatriz Frade-Sosa, Juan C Sarmiento-Monroy, Virginia Ruiz-Esquide, José A Gómez-Puerta, Raimon Sanmartí, Julio Ramírez
BACKGROUND: Inflammatory arthritis encompasses a group of immune-mediated diseases characterized by chronic joint inflammation. Despite having pathogenic mechanisms in common, the prognosis of rheumatoid arthritis (RA), psoriatic arthritis (PsA), and undifferentiated arthritis (UA) could be different regarding progression to chronic, to erosive, or to self-limited disease. Our aim was to evaluate the potential association of synovial tissue (ST) inflammatory cell infiltrate, the presence of ectopic lymphoid neogenesis (LN +) structures, and poor prognosis factors (PPF) in patients with RA, PsA, and UA...
January 10, 2024: Arthritis Research & Therapy
#18
JOURNAL ARTICLE
Gianluca Smerilli, Edoardo Cipolletta, Andrea Di Matteo, Marco Di Carlo, Erica Moscioni, Francesca Francioso, Davide Zompa, Maria Giovanna Lommano, Walter Grassi, Emilio Filippucci
OBJECTIVES: We aimed to 1) evaluate by power Doppler (PD) ultrasound (US) the response to therapy of the most inflamed joint and enthesis (target sites) in psoriatic arthritis (PsA) patients starting a biologic disease-modifying anti-rheumatic drug (bDMARD); and 2) to investigate the correlation between the US response and clinical data. METHODS: Consecutive PsA patients with US synovitis and US 'active' enthesitis, starting a bDMARD, were included. The joint with the highest OMERACT-EULAR-US composite score and the enthesis with the highest PD grade (targets) were identified at baseline...
January 8, 2024: Clinical and Experimental Rheumatology
#19
JOURNAL ARTICLE
Yiyi Wang, Nuozhou Liu, Lingyan Zhang, Min Yang, Yue Xiao, Furong Li, Hongxiang Hu, Li Qiu, Wei Li
OBJECTIVES: Psoriatic arthritis (PsA) is the most prevalent coexisting condition associated with psoriasis. Early-stage PsA patients always present unspecific and subtle clinical manifestations causing delayed diagnosis and leading to unfavorable health outcomes. The application of ultrasound enables precise identification of inflammatory changes in musculoskeletal structures. Hence, we constructed ultrasound models to aid early diagnosis of PsA. METHODS: This is a cross-sectional study carried out in the Department of Dermatology at West China Hospital (October 2018-April 2021)...
December 26, 2023: Rheumatology
#20
JOURNAL ARTICLE
Akihiko Asahina, Yukie Minami, Hideto Kameda
Patients with psoriatic arthritis (PsA) often experience comorbid, irreversible joint destruction, therefore early diagnosis and treatment of PsA are important. The diagnosis requires a comprehensive assessment, which includes an interview, a physical examination, a visual examination of the skin and nails, a blood test, and an imaging test. To clarify how patients with PsA are actually diagnosed and how physicians collaborate among clinical departments, we conducted a web-based questionnaire survey of 500 physicians (dermatologists, rheumatologists, and orthopedists) frequently involved in PsA treatment in Japan...
December 12, 2023: Journal of Dermatology
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