Norma Tolaba, Yamila Spedaletti, Paola Bazzoni, Macarena Galindez, Valeria Cerioni, Cecilia Santillan, Gilda Richter, Cecilia Herrera, Laura Sanchez, Leopoldo Van Cauwlaert, Marta A Toscano, Marcelo Nallar, Marcelo Monteros Alvi, Christian Martín Moya
BACKGROUND: The study of genetic mutations in thyroid nodules makes it possible to improve the preoperative diagnosis of and reduce unnecessary surgeries on benign nodules. In this study, we analysed the impact of implementing a 7-gene mutation panel that enables mutations to be detected in BRAF and RAS (H/N/K) and the gene fusions PAX8/PPARG, RET/PTC1 and RET/PTC2, in a population in northern Argentina. METHOD: We performed a prospective analysis of 112 fine needle aspirations diagnosed as having indeterminate cytology according to the Bethesda classification system...
June 22, 2021: Endocrinología, diabetes y nutrición