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JOURNAL ARTICLE
Mohammad Reza Keramati, Seyed Mostafa Meshkati Yazd, Mostafa Omidi, Amir Keshvari, Sepehr Shahriarirad, Reza Shahriarirad, Seyed Mohsen Ahmadi-Tafti, Behnam Behboudi, Alireza Kazemeini, Leyla Sahebi, Mohammad Sadegh Fazeli
INTRODUCTION: The effective treatment of anal fistulas almost always requires surgical intervention, which could be accompanied by post-operative complications, and affect the quality of life of patients. This study aimed to cross-culturally adapt the Persian version of the Quality of Life in patients with Anal Fistula questionnaire and evaluate its validity and reliability. MATERIALS AND METHODS: Sixty patients with a mean age of 44 years ranging from 21 to 72 years entered the study...
2023: PloS One
#42
JOURNAL ARTICLE
M Nguyen, G Beltramo, S Audia, H Devilliers, A Laurent, M Blot
RATIONALE: Objective structured clinical examinations (OSCEs) were introduced to evaluate students not only on their knowledge, but also on their clinical skills and attitudes. The objectives were to study the correlation between OSCE scores and scores obtained to traditional knowledge examinations and to analyse factors associated with better OSCE performance in DFASM1 and 2 students at Dijon university hospital. METHODS: This was a prospective observational study conducted among all fourth and fifth year medical students in Dijon...
April 4, 2023: La Revue de Médecine Interne
#43
Telila Mesfin, Nuri Haji, Fikadu Seyoume, Kenbon Seyoum, Eshetu Mesfin, Tsegaye Erdachew, Daniel Ayane, Gadisa Badasa, Moisan Soboka
INTRODUCTION: The term "disorders of sexual differentiation" refers to a variety of issues that result in the baby's genitalia being underdeveloped or showing characteristics shared by both sexes. Normal sexual development in utero requires a precise and coordinated spatiotemporal sequence of numerous activating and suppressing factors. Inadequate development of the bipotential gonad into an ovary or a testis is one of the most frequent causes of genital ambiguity (partial gonadal dysgenesis)...
2023: International Medical Case Reports Journal
#44
JOURNAL ARTICLE
Vanessa Arias Constanti, Araceli Domingo Garau, Belén Rodríguez Marrodán, Enrique Villalobos Pinto, Mónica Riaza Gómez, Laura García Soto, Ángel Hernández Borges, Aurora Madrid Rodríguez
INTRODUCTION: There are many initiatives aimed at eliminating health care interventions of limited utility in clinical practice. The Committee on Care Quality and Patient Safety of the Spanish Association of Pediatrics (AEP) has proposed the development of "DO NOT DO" recommendations (DNDRs) to establish a series of practices to be avoided in the care of paediatric patients in primary, emergency, inpatient and home-based care. MATERIAL AND METHODS: The project was carried out in 2 phases: a first phase in which possible DNDRs were proposed, and a second in which the final recommendations were established by consensus using the Delphi method...
March 18, 2023: Anales de pediatría
#45
JOURNAL ARTICLE
Minsung Kim, Bo-Young Oh, Ji-Seon Lee, Dogeon Yoon, You-Rin Kim, Wook Chun, Jong Wan Kim, Il Tae Son
OBJECTIVE: Studies on development of an anal incontinence (AI) model targeting smooth muscle cells (SMCs) of the internal anal sphincter (IAS) have not been reported. The differentiation of implanted human adipose-derived stem cells (hADScs) into SMCs in an IAS-targeting AI model has also not been demonstrated. We aimed to develop an IAS-targeting AI animal model and to determine the differentiation of hADScs into SMCs in an established model. MATERIALS AND METHODS: The IAS-targeting AI model was developed by inducing cryoinjury at the inner side of the muscular layer via posterior intersphincteric dissection in Sprague-Dawley rats...
February 17, 2023: Journal of Clinical Medicine
#46
JOURNAL ARTICLE
Carlo Ratto, Angelo Alessandro Marra, Angelo Parello, Veronica De Simone, Paola Campennì, Francesco Litta
Traditional fistulotomy is the most performed surgical procedure in anal fistula surgery. We conducted an international online survey to explore colorectal surgeons' opinions and preferences on fistulotomy. Considering the healing and continence impairment rates reported in the literature, surgeons were invited to answer as a hypothetic patient susceptible to being submitted to fistulotomy for low and high anal fistula. A total of 767 surgeons completed the survey from 72 countries. The majority of respondents were consultants, having treated more than 20 anal fistulas in the last year...
January 20, 2023: Journal of Clinical Medicine
#47
JOURNAL ARTICLE
Nicha Mongkolrat, Areerath Akatvipat, Phitchaya Saenubol, Pachara Pornnimitara, Sukolrat Boonyayatra, Siam Tongprasert
This study aimed to find methods and interferences and illustrate the pattern of external anal sphincter (EAS) electromyography (EMG) during micturition and to determine reference intervals of electrophysiological bulbocavernosus reflex (EBCR) by using robust statistical methods in healthy spayed female canines. Ten healthy spayed female canines (no breed restriction) with a body weight of 11.3-18 kg were enrolled. EAS EMG during micturition and the EBCR test were performed under light general anesthesia...
2023: Veterinary Medicine International
#48
JOURNAL ARTICLE
Gábor Barcsák, Anna Szilágyi, Róbert Jaskó, Mikolt Szigeti, Áron Altorjay
In our case report, we describe a rare form of metastatic colorectal carcinoma, in which tumor cells spread intraluminally and metastasis occurs with implantation mechanism far from the primary tumor. A 43-year-old male patient developed perianal abscess. After surgical intervention a fistula-in-ano appeared at the site of the abscess. Fistulotomy was performed in another hospital. A few months later, we admitted him to our department with an abnormal tissue proliferation appearing in the surgical area. Histology confirmed adenocarcinoma...
January 22, 2023: Orvosi Hetilap
#49
JOURNAL ARTICLE
Jia-He Yu, Xiang-Wu Huang, Yu-Cheng Song, Hui-Zhong Lin, Feng-Wu Zheng
BACKGROUND: Anastomotic leakage is one of the most serious complications that can occur after laparoscopic-assistedsphincter-preserving surgery for middle- and low-grade rectal cancer. OBJECTIVES: To explore the cause, prevention, and treatment of anastomotic leakage after sphincter-preserving surgery for middle- and low-grade rectal cancer under laparoscopy. METHODS: The clinical data from patients with mid- and low-grade rectal cancer who underwent laparoscopic-assistedanus-preserving surgery in the anorectal surgery department of our hospital have been analyzed...
2022: International Journal of Clinical Practice
#50
JOURNAL ARTICLE
Matteo Riccò
Monkeypox virus (MPXV), genus Orthopoxvirus, is a large double-stranded DNA virus (200-250 nm), that is evolutionarily related to human variola virus (VARV) (1), and causes a clinical syndrome quite similar to smallpox, with a generally less severe outcome (1,2). MPXV has a wide range of hosts and reservoirs in wild animals, and since 1970 has been commonly acknowledged as a human pathogen, endemic to Central and Western African countries through two distinctive clades (2,3). Central African clade (CAC) is responsible of the majority of 20,000 incident cases of the last decade, with a case-fatality-ratio of 7-10%, compared to < 4% for Western African clade (WAC) (4)...
December 16, 2022: Acta Bio-medica: Atenei Parmensis
#51
JOURNAL ARTICLE
Ana Choperena, Yvonne Gavela-Ramos, Marta Lizarbe-Chocarro, María José Galán-Espinilla, Begoña Errasti-Ibarrondo, Virginia La Rosa-Salas, Mónica Vázquez-Calatayud, Brendan McCormack, Ana Carvajal-Valcárcel
BACKGROUND: Person-centered care has become a key global approach that seeks to provide answers to all factors of the complex health care-related processes. This has led to the development of theoretical frameworks that represent the components of person-centered care. The internationally recognized Person-Centred Practice Framework (PCPF) (McCormack and McCance) allows multidisciplinary teams to understand and operationalize the dimensions for the development of person-centered care...
December 7, 2022: Anales del Sistema Sanitario de Navarra
#52
JOURNAL ARTICLE
(no author information available yet)
Fufang Jingjie for Fumigation and Washing is one of the commonly used and effective drugs for external fumigation and washing of traditional Chinese medicine, it has the functions of dispelling wind, drying and dampness, alleviating edema, and reducing swelling, relieving pain and relieving itching. It is widely used for the treatment of external hemorrhoids, mixed hemorrhoids, internal hemorrhoids prolapse and incarceration, anal fissures, perianal abscess, anal fistula acute attack, perianal eczema and other diseases...
November 2022: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
#53
COMMENT
Muhddesa Lakhana, Moshe Fenster, Aaron E Glatt
Tarín-Vicente EJ, Alemany A, Agud-Dios M, et al. Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. Lancet. 2022;400:661-9. 35952705.
December 2022: Annals of Internal Medicine
#54
JOURNAL ARTICLE
Mei-Ling Zhao, Feng-Jing Zhang, Wen-Rong Jiang, Yinyin Xia, Chang Chen, Ting Zhang, Ting-Li Han, Xin-Yang Yu, Peter Mei, Hong-Mei Zhang, Xin Jin, Boris Novakovic, Pamela Leong, Murray Thompson, Richard Saffery, Richard D Cannon, Hua Zhang, Ping Ji
INTRODUCTION: Oral health is a fundamental component of well-being, and is closely associated with overall health and quality of life. Oral health may also affect the next generation. The children of mothers with poor oral health are likely to also have poor oral health as they go through life. We aim to investigate associations between maternal oral health and general health, pregnancy outcomes, offspring oral health and offspring general health. METHODS AND ANALYSIS: The Lifetime Impact of Oral Health study is a prospective, observational cohort study being done at a single centre in Chongqing, China...
November 29, 2022: BMJ Open
#55
JOURNAL ARTICLE
Shan Muhammad, YiBo Gao, Xu Guan, Tang QingChao, Shao Fei, Guiyu Wang, Yinggang Chen, Zheng Liu, Zheng Jiang, Kavanjit Kaur, Kamchedalova Tatiana, Qurat Ul Ain, Xishan Wang, Jie He
OBJECTIVE: To evaluate the feasibility, safety, and short-term outcomes of middle rectal resection followed by transanal specimen extraction. METHODS: Forty-four patients with small mid-rectal tumors underwent laparoscopic rectal resection followed by transanal specimen extraction. RESULTS: The procedure was successful in all patients without intraoperative conversion or additional access. The mean operation time was 182.7 minutes (range, 130-255 minutes), the mean blood loss was 26...
November 2022: Journal of International Medical Research
#56
REVIEW
Anna Burdzinska, Marek Galanty, Sabina Więcek, Filip A Dabrowski, Ahmed Lotfy, Tomasz Sadkowski
The effective treatment of perianal fistulizing Crohn's disease is still a challenge. Local administration of mesenchymal stromal cells (MSCs) is becoming a part of accepted treatment options. However, as a fledgling technique, it still can be optimized. A new trend in translational research, which is in line with "One Health" approach, bases on exploiting parallels between naturally occurring diseases affecting humans and companion animals. Canine anal furunculosis (AF) has been indicated as condition analogous to human perianal Crohn's disease (pCD)...
November 11, 2022: International Journal of Molecular Sciences
#57
JOURNAL ARTICLE
Shuai Yuan, Jing Sun, Ying Lu, Fengzhe Xu, Doudou Li, Fangyuan Jiang, Zhongxiao Wan, Xue Li, Li-Qiang Qin, Susanna C Larsson
BACKGROUND: We performed phenome-wide Mendelian randomization analysis (MR-PheWAS), two-sample MR analysis, and systemic review to comprehensively explore the health effects of milk consumption in the European population. METHODS: Rs4988235 located upstream of the LCT gene was used as the instrumental variable for milk consumption. MR-PheWAS analysis was conducted to map the association of genetically predicted milk consumption with 1081 phenotypes in the UK Biobank study (n=339,197)...
November 23, 2022: BMC Medicine
#58
JOURNAL ARTICLE
John P Thornhill, Romain Palich, Jade Ghosn, Sharon Walmsley, Davide Moschese, Claudia P Cortes, Rafael Mello Galliez, Amy B Garlin, Silvia Nozza, Oriol Mitja, Asa E Radix, Jose Luis Blanco, Brenda Crabtree-Ramirez, Melanie Thompson, Lothar Wiese, Hubert Schulbin, Ariela Levcovich, Marco Falcone, Anna Lucchini, Elena Sendagorta, Carl-Johan Treutiger, Ruth Byrne, Katherine Coyne, Eric A Meyerowitz, Anna M Grahn, Ann-Brit Eg Hansen, Valerie Pourcher, Michelle DellaPiazza, Rachel Lee, Marcel Stoeckle, Aniruddha Hazra, Vanessa Apea, Emma Rubenstein, Joyce Jones, Aimee Wilkin, Anuradha Ganesan, Andrés F Henao-Martínez, Eric J Chow, Boghuma K Titanji, Jason E Zucker, Dimie Ogoina, Chloe M Orkin
BACKGROUND: Between May and November, 2022, global outbreaks of human monkeypox virus infection have been reported in more than 78 000 people worldwide, predominantly in men who have sex with men. We describe the epidemiological and clinical characteristics of monkeypox virus infection in cisgender (cis) and transgender (trans) women and non-binary individuals assigned female sex at birth to improve identification and understanding of risk factors. METHODS: International collaborators in geographical locations with high numbers of diagnoses of monkeypox virus infection were approached and invited to contribute data on women and non-binary individuals with confirmed monkeypox virus infection...
December 3, 2022: Lancet
#59
REVIEW
Oriol Mitjà, Dimie Ogoina, Boghuma K Titanji, Cristina Galvan, Jean-Jacques Muyembe, Michael Marks, Chloe M Orkin
Monkeypox is a zoonotic illness caused by the monkeypox virus, an Orthopoxvirus in the same genus as the variola, vaccinia, and cowpox viruses. Since the detection of the first human case in the Democratic Republic of the Congo in 1970, the disease has caused sporadic infections and outbreaks, mainly restricted to some countries in west and central Africa. In July, 2022, WHO declared monkeypox a Public Health Emergency of International Concern, on account of the unprecedented global spread of the disease outside previously endemic countries in Africa and the need for global solidarity to address this previously neglected disease...
January 7, 2023: Lancet
#60
Foram P Joshi
Myiasis is an uncommon pathology of parasitic infestation in live mammals by fly larvae (maggots). The fly grows and gets nourished by invading host tissue. Epidemiology of Myiasis has been recorded in tropical regions of world. No any documentation has been found on Ayurvedic intervention for anal myiasis management. The study is about a 49-year male having anal myiasis along and interno-external piles together. The case was managed by local application of Neem oil (Medicated oil of Azadirachta indica Linn...
November 15, 2022: Journal of Ayurveda and Integrative Medicine
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