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JOURNAL ARTICLE
Mei-Ling Zhao, Feng-Jing Zhang, Wen-Rong Jiang, Yinyin Xia, Chang Chen, Ting Zhang, Ting-Li Han, Xin-Yang Yu, Peter Mei, Hong-Mei Zhang, Xin Jin, Boris Novakovic, Pamela Leong, Murray Thompson, Richard Saffery, Richard D Cannon, Hua Zhang, Ping Ji
INTRODUCTION: Oral health is a fundamental component of well-being, and is closely associated with overall health and quality of life. Oral health may also affect the next generation. The children of mothers with poor oral health are likely to also have poor oral health as they go through life. We aim to investigate associations between maternal oral health and general health, pregnancy outcomes, offspring oral health and offspring general health. METHODS AND ANALYSIS: The Lifetime Impact of Oral Health study is a prospective, observational cohort study being done at a single centre in Chongqing, China...
November 29, 2022: BMJ Open
#62
JOURNAL ARTICLE
Shan Muhammad, YiBo Gao, Xu Guan, Tang QingChao, Shao Fei, Guiyu Wang, Yinggang Chen, Zheng Liu, Zheng Jiang, Kavanjit Kaur, Kamchedalova Tatiana, Qurat Ul Ain, Xishan Wang, Jie He
OBJECTIVE: To evaluate the feasibility, safety, and short-term outcomes of middle rectal resection followed by transanal specimen extraction. METHODS: Forty-four patients with small mid-rectal tumors underwent laparoscopic rectal resection followed by transanal specimen extraction. RESULTS: The procedure was successful in all patients without intraoperative conversion or additional access. The mean operation time was 182.7 minutes (range, 130-255 minutes), the mean blood loss was 26...
November 2022: Journal of International Medical Research
#63
REVIEW
Anna Burdzinska, Marek Galanty, Sabina Więcek, Filip A Dabrowski, Ahmed Lotfy, Tomasz Sadkowski
The effective treatment of perianal fistulizing Crohn's disease is still a challenge. Local administration of mesenchymal stromal cells (MSCs) is becoming a part of accepted treatment options. However, as a fledgling technique, it still can be optimized. A new trend in translational research, which is in line with "One Health" approach, bases on exploiting parallels between naturally occurring diseases affecting humans and companion animals. Canine anal furunculosis (AF) has been indicated as condition analogous to human perianal Crohn's disease (pCD)...
November 11, 2022: International Journal of Molecular Sciences
#64
JOURNAL ARTICLE
Shuai Yuan, Jing Sun, Ying Lu, Fengzhe Xu, Doudou Li, Fangyuan Jiang, Zhongxiao Wan, Xue Li, Li-Qiang Qin, Susanna C Larsson
BACKGROUND: We performed phenome-wide Mendelian randomization analysis (MR-PheWAS), two-sample MR analysis, and systemic review to comprehensively explore the health effects of milk consumption in the European population. METHODS: Rs4988235 located upstream of the LCT gene was used as the instrumental variable for milk consumption. MR-PheWAS analysis was conducted to map the association of genetically predicted milk consumption with 1081 phenotypes in the UK Biobank study (n=339,197)...
November 23, 2022: BMC Medicine
#65
JOURNAL ARTICLE
John P Thornhill, Romain Palich, Jade Ghosn, Sharon Walmsley, Davide Moschese, Claudia P Cortes, Rafael Mello Galliez, Amy B Garlin, Silvia Nozza, Oriol Mitja, Asa E Radix, Jose Luis Blanco, Brenda Crabtree-Ramirez, Melanie Thompson, Lothar Wiese, Hubert Schulbin, Ariela Levcovich, Marco Falcone, Anna Lucchini, Elena Sendagorta, Carl-Johan Treutiger, Ruth Byrne, Katherine Coyne, Eric A Meyerowitz, Anna M Grahn, Ann-Brit Eg Hansen, Valerie Pourcher, Michelle DellaPiazza, Rachel Lee, Marcel Stoeckle, Aniruddha Hazra, Vanessa Apea, Emma Rubenstein, Joyce Jones, Aimee Wilkin, Anuradha Ganesan, Andrés F Henao-Martínez, Eric J Chow, Boghuma K Titanji, Jason E Zucker, Dimie Ogoina, Chloe M Orkin
BACKGROUND: Between May and November, 2022, global outbreaks of human monkeypox virus infection have been reported in more than 78 000 people worldwide, predominantly in men who have sex with men. We describe the epidemiological and clinical characteristics of monkeypox virus infection in cisgender (cis) and transgender (trans) women and non-binary individuals assigned female sex at birth to improve identification and understanding of risk factors. METHODS: International collaborators in geographical locations with high numbers of diagnoses of monkeypox virus infection were approached and invited to contribute data on women and non-binary individuals with confirmed monkeypox virus infection...
December 3, 2022: Lancet
#66
REVIEW
Oriol Mitjà, Dimie Ogoina, Boghuma K Titanji, Cristina Galvan, Jean-Jacques Muyembe, Michael Marks, Chloe M Orkin
Monkeypox is a zoonotic illness caused by the monkeypox virus, an Orthopoxvirus in the same genus as the variola, vaccinia, and cowpox viruses. Since the detection of the first human case in the Democratic Republic of the Congo in 1970, the disease has caused sporadic infections and outbreaks, mainly restricted to some countries in west and central Africa. In July, 2022, WHO declared monkeypox a Public Health Emergency of International Concern, on account of the unprecedented global spread of the disease outside previously endemic countries in Africa and the need for global solidarity to address this previously neglected disease...
January 7, 2023: Lancet
#67
Foram P Joshi
Myiasis is an uncommon pathology of parasitic infestation in live mammals by fly larvae (maggots). The fly grows and gets nourished by invading host tissue. Epidemiology of Myiasis has been recorded in tropical regions of world. No any documentation has been found on Ayurvedic intervention for anal myiasis management. The study is about a 49-year male having anal myiasis along and interno-external piles together. The case was managed by local application of Neem oil (Medicated oil of Azadirachta indica Linn...
November 15, 2022: Journal of Ayurveda and Integrative Medicine
#68
JOURNAL ARTICLE
Marc Liautard, Céline Deguette, Elizabeth Alcaraz, Hélène Diot, Patricia Vasseur, Charlotte Gorgiard, Laurène Dufayet
Sexual violence is a common and under-reported form of violence that affects all categories of individuals. We sought to provide epidemiological data on men aged 15 years and over, victims of rape or suspecting a rape, and who reported it to the police. We conducted a retrospective study at the Department of Forensic Medicine of Hôtel-Dieu, Paris, France, between 2018 and 2021. Two-hundred men were included in the study, with an average age of 28.8 years. A vulnerability was mentioned for 17.5% of them. Most of the patients reported anal penetration, committed by a single male assailant, whom they met on the day of the assault...
October 26, 2022: International Journal of Environmental Research and Public Health
#69
JOURNAL ARTICLE
Justin Y van Oostendorp, Lisette Dekker, Susan van Dieren, Willem A Bemelman, Ingrid J M Han-Geurts
INTRODUCTION: Perianal fistula is a burdening disease with an annual incidence of 6-12/100 000 in Western countries. More than 90% of crypto-glandular fistulas originate from perianal abscess. Despite adequate drainage, up to 83% recur or result in an anal fistula, the majority developing within 12 months. There is some evidence that gut-derived bacteria play a role in the development of perianal fistula. Up till now, it is not common practice to routinely administer prophylactic antibiotics to prevent anal fistula development...
November 8, 2022: BMJ Open
#70
JOURNAL ARTICLE
Jocelyn Mesías-Gazmuri, Cinta Folch, Laia Ferrer, Juliana Reyes-Urueña, Laia Egea-Cortés, Adriana Morales, Luis Villegas, Jordi Casabona
BACKGROUND: Transgender women and cisgender men sex workers are vulnerable to HIV and sexually transmitted infections (STIs). This study aimed to explore in depth the prevalence of syndemic conditions and their association with the sexual risk behaviors for HIV/STI acquisition in cis men and trans women sex workers in Barcelona (Catalonia, Spain). METHOD: We conducted a study between 2014 and 2018 to determine whether syndemic conditions (frequent alcohol consumption and polydrug use (> 2) during sex with clients; experience of violence; and lack of healthcare access) are associated with HIV/STI sexual risk behaviors...
November 4, 2022: International Journal of Behavioral Medicine
#71
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 2022: Sexual Health
#72
JOURNAL ARTICLE
Navkiran Randhawa, Ahamed Khalyfa, Rida Aslam, M Christopher Roebuck, Mahnoor Inam, Kamran Ayub
Background: Anal fissures cause severe pain and can be difficult to treat. Medical therapy is initially used, followed by sigmoidoscopy-guided botox injections if the medical therapy is not successful. With this technique, however, it is not clear whether botox is injected into the muscle layer or submucosa. Aim: To evaluate the efficacy of EUS-guided botox injection directly into the internal sphincter. Methods: Consecutive patients with chronic anal fissure refractory to conventional endoscopic botulinum toxin type A injection were enrolled in the study...
October 21, 2022: Journal of Clinical Medicine
#73
Hunza Chaudhry, Sunny Sandhu, David Tasso, Devang Prajapati
Squamous cell carcinoma (SCC) of the rectum is a rare malignancy, and the optimal treatment strategy remains unknown. Cases are limited in the literature, and although historically treated with surgical resection, more recent cases have suggested success with chemotherapy. Although Nigro protocol was initially developed for anal SCC, we present a case of rectal SCC successfully treated with the Nigro protocol. Our case supports the use of chemoradiotherapy as initial treatment for rectal SCC over surgery.
2022: Journal of Community Hospital Internal Medicine Perspectives
#74
JOURNAL ARTICLE
Devon J Hensel, Rosalia Misseri, John S Wiener, Joshua D Roth, Benjamin M Whittam, Mark P Cain, Konrad M Szymanski
BACKGROUND: Spina bifida (SB) may differentially impact adults' participation in solo and partnered sexual behaviors, but little research investigates this topic. AIM: Describe solo and partnered sexual behaviors among an international sample of adult men and women with SB. MAIN OUTCOME MEASURES: Ever participated (no/yes) and recent participation (>1 year ago/within last year) in solo masturbation, cuddled with a partner, held hands with a partner, kissed a partner, touched a partner's genital, had genitals touched by a partner, gave a partner oral sex, received oral sex from a partner, vaginal sex, anal sex, and sex toy use...
December 2022: Journal of Sexual Medicine
#75
RANDOMIZED CONTROLLED TRIAL
G Mustafa, M S Hossain, S H Sheikh, I Faruk, M A Taher, A M Ferdaus, B Fatema, A Alam, T Tasnim
The objective of study was to evaluate the clinical outcome of topical 0.2% Glyceryl trinitrate topical (GTN) ointment in the treatment of chronic anal fissure. This randomized control trial was carried out in the Colorectal Surgery Unit, Department of Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh from May 2015 to April 2016. Total 94 patients were included in this trial, where 47(50.0%) patients were treated by 0.2% GTN ointment as Trial group 12 hourly for 8 weeks and 47(50.0%) patients by lateral internal sphincterotomy (LIS) as Control group in this study...
October 2022: Mymensingh Medical Journal: MMJ
#76
Si-Le Cheng, Lu Xie, Hao-Wei Wu, Xiao-Feng Zhang, Li-Lan Lou, Hong-Zhang Shen
BACKGROUND: Acute iatrogenic colorectal perforation (AICP) is a serious adverse event, and immediate AICP usually requires early endoscopic closure. Immediate surgical repair is required if the perforation is large, the endoscopic closure fails, or the patient's clinical condition deteriorates. In cases of delayed AICP (> 4 h), surgical repair or enterostomy is usually performed, but delayed rectal perforation is rare. CASE SUMMARY: A 53-year-old male patient underwent endoscopic submucosal dissection (ESD) at a local hospital for the treatment of a laterally spreading tumor of the rectum, and the wound was closed by an endoscopist using a purse-string suture...
August 16, 2022: World Journal of Clinical Cases
#77
JOURNAL ARTICLE
Faisal Ahmad, Clement De Loubens, Albert Magnin, Alain Dubreuil, Jean-Luc Faucheron, Stephane Tanguy
Despite the numerous available clinical investi-gation tests, the associated alteration of quality of life and the socio-economic cost, it remains difficult for physicians to identify the pathophysiological origins of defecation disorders and therefore to provide the appropriate clinical care. Based on standardized dynamic X-ray defecography, we developed a 2D patient-specific computational fluid dynamic model of rectal evacuation. X-ray defecography was carried out in a sitting position with a standardized paste whose yield stress matched that of soft human feces...
July 2022: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
#78
JOURNAL ARTICLE
Pankaj Garg, Vipul D Yagnik, Baljit Kaur, Geetha R Menon, Sushil Dawka
BACKGROUND: The transanal opening of intersphincteric space (TROPIS) procedure, performed to treat complex anal fistulas, preserves the external anal sphincter (EAS) but involves partial incision of the internal anal sphincter (IAS). AIM: To ascertain the incidence of incontinence after the division of the IAS as is done in TROPIS and to evaluate whether regular Kegel exercises (KE) in the postoperative period can prevent incontinence due to IAS division. METHODS: Patients operated on for high complex fistulas and having no preoperative continence problem (score = 0) were included in the study...
July 16, 2022: World Journal of Clinical Cases
#79
JOURNAL ARTICLE
Qidi Zhou, Weizi Wu, Mengyao Yi, Yan Shen, Lloyd Goldsamt, Asem Alkhatib, Wenjing Jiang, Xianhong Li
OBJECTIVE: China has seen an increasing number of international students in recent years, mostly from Africa and Asia. However, little is known about these students' HIV knowledge, sexual practices and potential HIV risk. This study aimed to describe HIV-related risk among international students. DESIGN: An online cross-sectional survey. SETTING: 10 universities situated in one province of China. PARTICIPANTS: 617 international students filled out the questionnaire and 607 international students were included in this study...
August 29, 2022: BMJ Open
#80
JOURNAL ARTICLE
Yimei Liao, Jing Jiang, Jin Luo, Wenwu Du, Weiwei Zhao, Yafeng Zhang
Purpose: The aim of the study is to explore the impact of perioperative pain care management on patients' pain, comfort, and defecation in anorectal surgery. Methods: From January to December 2021, 126 patients who underwent anorectal surgery in our department were selected for the study and were randomly divided into a study group and a control group of 63 patients each after consent was obtained from the patients. The control group was given the usual care protocol and the study group was given the perioperative pain care management on top of the usual care...
2022: Emergency Medicine International
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