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JOURNAL ARTICLE
Sanjay Basu, John S Yudkin, Mohammed Jawad, Hala Ghattas, Bassam Abu Hamad, Zeina Jamaluddine, Gloria Safadi, Marie-Elizabeth Ragi, Raeda El Sayed Ahmad, Eszter P Vamos, Christopher Millett
We sought to assess the effectiveness and cost-effectiveness of potential new public health and healthcare NCD risk reduction efforts among Palestinians in Gaza. We created a microsimulation model using: (i) a cross-sectional household survey of NCD risk factors among 4,576 Palestinian adults aged ≥40 years old in Gaza; (ii) a modified Delphi process among local public health experts to identify potentially feasible new interventions; and (iii) reviews of intervention cost and effectiveness, modified to the Gazan and refugee contexts...
2024: PLOS Glob Public Health
#2
JOURNAL ARTICLE
Lucian Batista de Oliveira, Mariana Andrade de Figueiredo Martins Siqueira, Rafael Buarque de Macedo Gadêlha, Jessica Garcia, Francisco Bandeira
BACKGROUND AND OBJECTIVES: Vitamin D, as a steroid hormone, has multiple effects on human body and its deficiency has been associated with an increased risk of heart failure (HF) and unfavorable outcomes. The present study investigated the prevalence of vitamin D deficiency (VDD) and its relationship with cardiometabolic parameters in patients hospitalized for HF living in the city of Recife (latitude 8° South). METHODS: Analytical cross-sectional study, with men and women aged 40-64 years...
April 2024: International journal of heart failure
#3
JOURNAL ARTICLE
Liwei Xing, Jinlong Xu, Yuanyuan Wei, Yang Chen, Haina Zhuang, Wei Tang, Shun Yu, Junbao Zhang, Guochen Yin, Ruirui Wang, Rong Zhao, Dongdong Qin
Polycystic ovary syndrome (PCOS) is one of the most prevalent gynecological endocrine conditions affecting reproductive women. It can feature a variety of symptoms, such as obesity, insulin resistance, skin conditions, and infertility. Women with PCOS are susceptible to illnesses including mood disorders, diabetes, hypertension, and dyslipidemia. Among them, depression is the most common in PCOS and has a detrimental effect on quality of life. Depression may occasionally develop due to the pathological traits of PCOS, but its exact pathogenesis in PCOS have eluded researchers to date...
January 2024: Focus: Journal of Life Long Learning in Psychiatry
#4
JOURNAL ARTICLE
Eliniete de Jesus Fidelis Baniwa, Eliene Rodrigues Putira Sacuena, Rosilene Reis Della Noce, Vanessa Barroso Quaresma, Teodora Honorato Alencar, Renan Barbosa Lemes, Antônia Cherlly Araújo, Izaura Maria Vieira Cayres-Vallinoto, João Farias Guerreiro
BACKGROUND: Available data show that the epidemiological profile of most indigenous Brazilian populations is characterized by the coexistence of long-standing health problems (high prevalence of infectious and parasitic diseases, malnutrition, and deficiency diseases, such as anemia in children and women of reproductive age), associated with new health problems, especially those related to obesity (hypertension, type 2 diabetes mellitus and dyslipidemia). Based on this scenario, this study analyzed the nutritional profile of the adult population of seven indigenous peoples from the Brazilian Amazon in the years 2007 and 2021...
May 1, 2024: BMC Public Health
#5
JOURNAL ARTICLE
Ioana Alexandra Cardos, Catalina Danila, Timea Claudia Ghitea, Ovidiu Pop, Andrei Pascalau, Simona Cavalu
BACKGROUND/AIM: H. pylori infection can promote a systemic inflammatory syndrome, eventually leading to intestinal metaplasia and gastric cancer. The aim of our study was to investigate the possible association between dyslipidemia and histopathological features of H. pylori gastritis. PATIENTS AND METHODS: An observational, retrospective study was conducted over the period 2017-2022 on symptomatic patients with a positive rapid urease test. A total of 121 patients who underwent upper gastrointestinal endoscopy with stomach biopsy were enrolled in this study...
2024: In Vivo
#6
JOURNAL ARTICLE
Preeta Kaur Chugh, Pooja Gupta, Himika Wasan, C D Tripathi, Sujith J Chandy, Jaya Ranjalkar, Heber Rew Bright, Dinesh Kumar Badyal, Madhulika Peter Samuel, Ratinder Jhaj, Aditya Banerjee, Rupa Joshi, Bikash Medhi, Ajay Prakash, Sandhya Kamat, Raakhi Tripathi, Yashashri Shetty, Urwashi Parmar, Harihar Dikshit, Hitesh Mishra, Sukalyan Saha Roy, Rajiv Kumar, Suparna Chatterjee, Manjari Bhattacharya, Kalyan Samanta, Niyati Trivedi, Prashant Shah, Janki Chauhan, Raveendran Ramasamy, Jayanthi Mathaiyan, Jeevitha Gauthaman, Sandeep Kaushal, Samriti Jain, Shalini Arora, Kanchan Gupta, Jerin Jose Cherian, Nabendu Sekhar Chatterjee, Nilima Arun Kshirsagar
OBJECTIVES: India has taken several initiatives to provide health care to its population while keeping the related expenditure minimum. Since cardiovascular diseases are the most prevalent chronic conditions, in the present study, we aimed to analyze the difference in prices of medicines prescribed for three cardiovascular risk factors, based on (a) listed and not listed in the National List of Essential Medicines (NLEM) and (b) generic and branded drugs. MATERIALS AND METHODS: Outpatient prescriptions for diabetes mellitus, hypertension, and dyslipidemia were retrospectively analyzed from 12 tertiary centers...
March 1, 2024: Indian Journal of Pharmacology
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JOURNAL ARTICLE
Rachel K Greene, Suma Gangidi, Raymond Zhao, Jessie M Nelson, Kelly Harms, Mio Nakamura
BACKGROUND: Acrochordons or skin tags are common benign skin growths. Several studies explored the relationship between obesity and metabolic syndrome in adults but remains unexplored in children. METHODS: This was a single-center retrospective cohort study of outpatient dermatology patients between 1 January 2000 to 1 January 2021. Children under 18 years old diagnosed with acrochordons using diagnostic codes International Classification of Diseases, 10th Revision (ICD-10) L91...
April 29, 2024: Pediatric Dermatology
#8
JOURNAL ARTICLE
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Dyslipidemia is the most frequent cardiovascular (CV) risk factor in able-bodied athletes and is frequently undertreated, resulting in an underestimated risk of atherosclerosis-related diseases. Data on lipid profile in Paralympic athletes are lacking. Our study aimed to identify the prevalence of dyslipidemia and the influence of disability type and sporting discipline in Paralympic athletes. We evaluated 289 athletes who participated in the Paralympic Games from London 2012 to Beijing 2022. All athletes underwent clinical/physical evaluation, blood tests, and body composition analysis...
January 1, 2024: American Journal of Cardiology
#9
EDITORIAL
Sonia Eiras
This editorial refers to the article "Comparative analysis of Nε-carboxymethyl-lysine and inflammatory markers in diabetic and non-diabetic coronary artery disease patients", published in the recent issue of the World Journal of Diabetes 2023 is based on glucose metabolism, advanced glycation end products (AGEs), inflammation and adiposity on diabetes and coronary artery disease (CAD). This study has included CAD patients who were stratified according to glycosylated hemoglobin higher than 6.5 and sex-matched...
April 15, 2024: World Journal of Diabetes
#10
JOURNAL ARTICLE
Le Zhang, Mortada El-Shabrawi, Louise A Baur, Christopher D Byrne, Giovanni Targher, Mohit Kehar, Gilda Porta, Way Seah Lee, Sander Lefere, Serap Turan, Anna Alisi, Ram Weiss, Maria Felicia Faienza, Ambika Ashraf, Shikha S Sundaram, Anshu Srivastava, Ruth De Bruyne, Yunkoo Kang, Flora Bacopoulou, Yong-Hai Zhou, Andy Darma, Monica Lupsor-Platon, Masahide Hamaguchi, Anoop Misra, Nahum Méndez-Sánchez, Nicholas Beng Hui Ng, Claude Marcus, Amanda E Staiano, Nadia Waheed, Saleh A Alqahtani, Cosimo Giannini, Ponsiano Ocama, Mindie H Nguyen, Maria Teresa Arias-Loste, Mohamed Rabea Ahmed, Giada Sebastiani, Yong Poovorawan, Mamun Al Mahtab, Juan M Pericàs, Themis Reverbel da Silveira, Peter Hegyi, Amer Azaz, Hasan M Isa, Chatmanee Lertudomphonwanit, Mona Issa Farrag, Ahmed Abd Alwahab Nugud, Hong-Wei Du, Ke-Min Qi, Nezha Mouane, Xin-Ran Cheng, Tawfiq Al Lawati, Eleonora D T Fagundes, Hasmik Ghazinyan, Adamos Hadjipanayis, Jian-Gao Fan, Nicoleta Gimiga, Naglaa M Kamal, Gabriela Ștefănescu, Li Hong, Smaranda Diaconescu, Ming Li, Jacob George, Ming-Hua Zheng
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in children and adolescents, particularly those with obesity. NAFLD is considered a hepatic manifestation of the metabolic syndrome due to its close associations with abdominal obesity, insulin resistance, and atherogenic dyslipidemia. Experts have proposed an alternative terminology, metabolic dysfunction-associated fatty liver disease (MAFLD), to better reflect its pathophysiology. This study aimed to develop consensus statements and recommendations for pediatric MAFLD through collaboration among international experts...
April 24, 2024: Med
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JOURNAL ARTICLE
Matteo Landolfo, Francesco Spannella, Alessandro Gezzi, Federico Giulietti, Lucia Sabbatini, Isabella Bari, Romina Alessandroni, Angelica Di Agostini, Paolo Turri, Francesco Alborino, Lorenzo Scoppolini Massini, Riccardo Sarzani
Background and aims: SCORE2/SCORE2-OP cardiovascular risk (CVR) charts and online calculators do not apply to patients with comorbidities, target organ damage, or atherosclerotic cardiovascular disease, for whom the assessment relies on the conventional consultation of the 2021 ESC guidelines (qualitative approach). To simplify the CVR evaluation, we developed an integrated multi-language and free-to-use web application. This study assessed the agreement between the conventional method versus our web app. Methods: A cross-sectional study was carried out on 1306 consecutive patients aged 40+ years referred to our center for the diagnosis and management of hypertension and dyslipidemia...
April 16, 2024: Journal of Clinical Medicine
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JOURNAL ARTICLE
Oh-Sung Kwon, Young-Kyu Kim, Hyeon Ju Kim
Background/Aims: Well-known risk factors for gallbladder polyps include metabolic syndrome, age, and dyslipidemia. Jeju Island is approximately 80 km from the Korean peninsula and is divided into two administrative regions (Jeju City and Seogwipo City), with Mount Halla intervening in the center. Jeju City has higher employment and birth rates than Seogwipo City. Age and alcohol consumption differ between the two regions, and these factors may affect the prevalence of gallbladder polyps (GBPs). Therefore, we investigated the prevalence of GBPs and compared various factors, including alcohol consumption habits and age, associated with GBPs among residents in the two regions...
April 15, 2024: Journal of Clinical Medicine
#13
JOURNAL ARTICLE
Ho-Joon Ko, Soon-Ki Ahn, Suyeon Han, Moo-Jun Kim, Ki Ryang Na, Hyerim Park, Dae Eun Choi
Background: The global prevalence of chronic kidney disease (CKD) is increasing, with diabetes accounting for the highest proportion. We analyzed the influence of clinical factors on the incidence of CKD according to the renal function, primary focusing on patients with diabetes. Methods: We used the Sample Cohorts Database provided by the National Health Insurance Sharing Service (NHISS) in Korea. Participants aged ≥ 40 years who underwent a health checkup in 2009 were categorized into six groups based on their eGFR values (<60 mL/min, 60-89 mL/min, ≥90 mL/min) and the presence of diabetes...
April 9, 2024: Journal of Clinical Medicine
#14
JOURNAL ARTICLE
Julia Vázquez-de Sebastián, Angel M Ortiz-Zuñiga, Andreea Ciudin, Joan Ars, Marco Inzitari, Rafael Simó, Cristina Hernández, Sergio Ariño-Blasco, María José Barahona, Maite Franco, Xavier Gironès, María Cruz Crespo-Maraver, Joan Carles Rovira, Carmina Castellano-Tejedor, The Dialcat Consortium
The prevalence of cardiovascular risk factors (CVRFs) in the older adults population and their specific impact on their cognitive profiles still requires further research. For this purpose, a cross-sectional study was carried out to describe the presence of CVRFs and their association with cognitive performance in a sample of older adults (65-85 years old) with Mild Cognitive Impairment (MCI). Participants ( n = 185) were divided into three groups concerning their cardiovascular risk level determined by the presence of different CVRFs, including Type 2 Diabetes (T2D), dyslipidemia, hypertension, and obesity...
April 18, 2024: International Journal of Environmental Research and Public Health
#15
REVIEW
Kenbon Beyene Abdisa, Emőke Szerdahelyi, Máté András Molnár, László Friedrich, Zoltán Lakner, András Koris, Attila Toth, Arijit Nath
Metabolic syndrome (MS) is defined by the outcome of interconnected metabolic factors that directly increase the prevalence of obesity and other metabolic diseases. Currently, obesity is considered one of the most relevant topics of discussion because an epidemic heave of the incidence of obesity in both developing and underdeveloped countries has been reached. According to the World Obesity Atlas 2023 report, 38% of the world population are presently either obese or overweight. One of the causes of obesity is an imbalance of energy intake and energy expenditure, where nutritional imbalance due to consumption of high-calorie fast foods play a pivotal role...
April 14, 2024: Biomolecules
#16
JOURNAL ARTICLE
Alexandra Herlo, Adelina Raluca Marinescu, Talida Georgiana Cut, Ruxandra Laza, Cristian Iulian Oancea, Diana Manolescu, Elena Hogea, Tamara Mirela Porosnicu, Suzana Vasilica Sincaru, Raluca Dumache, Sorina Ispas, Andreea Nelson Twakor, Maria Nicolae, Voichita Elena Lazureanu
The emergence of SARS-CoV2 has presented itself as a significant global health crisis. The prevalence of thrombotic events is known to be high in these patients, affecting various organ systems, sometimes leading to cutaneous thrombosis, pulmonary embolism (PE), stroke, or coronary thrombosis. The available evidence suggests that thromboembolism, hypercoagulability, and the excessive production of proinflammatory cytokines play a significant role in the development of multiorgan failure. Methodology: This retrospective single-centre study was conducted at "Victor Babes" University of Medicine and Pharmacy from Timisoara, Romania, involving a total of 420 patients diagnosed with COVID-19...
April 1, 2024: Biomedicines
#17
JOURNAL ARTICLE
Salvatore Martini, Elena Delfina Ricci, Addolorata Masiello, Sergio Zacà, Benedetto Maurizio Celesia, Sergio Ferrara, Giovanni Di Filippo, Alessandra Tartaglia, Rosa Basile, Domenico Angiletta, Paolo Maggi
BACKGROUND: Antiretroviral therapy has allowed a clear improvement in prognosis for HIV patients, but metabolic problems, such as dyslipidemia, remain. This can lead to the development of atheromatous plaques. Our study aims to evaluate whether HIV-positive (HIV+) patients show higher myo-intimal media thickness (IMT) and atheromatous plaques compared to HIV-negative (HIV-) patients. METHODS: To evaluate the association between HIV infection in experienced patients and vascular pathology, we performed a cross-sectional study, observing 1006 patients, 380 HIV+ enrolled in the Archiprevaleat cohort, and 626 HIV- as a control group...
April 1, 2024: Biomedicines
#18
REVIEW
Alexandra-Ioana Dănilă, Laura Andreea Ghenciu, Emil Robert Stoicescu, Sorin Lucian Bolintineanu, Roxana Iacob, Mihai-Alexandru Săndesc, Alexandra Corina Faur
The escalating global prevalence of diabetes mellitus (DM) over the past two decades has led to a persistent high incidence of diabetic retinopathy (DR), necessitating screening for early symptoms and proper treatment. Effective management of DR aims to decrease vision impairment by controlling modifiable risk factors including hypertension, obesity, and dyslipidemia. Moreover, systemic medications and plant-based therapy show promise in advancing DR treatment. One of the key mechanisms related to DR pathogenesis is the polyol pathway, through which aldose reductase (AR) catalyzes the conversion of glucose to sorbitol within various tissues, including the retina, lens, ciliary body and iris...
March 27, 2024: Biomedicines
#19
JOURNAL ARTICLE
Leticia Rodrigues-Oliveira, César Rivera, Xaviera A López-Cortés, Milena Perez Mak, Ana Leticia Mores, Cesar Augusto Migliorati, Maria Cecília Querido de Oliveira, Natalia Rangel Palmier, Luiz Alcino Gueiros, Pablo Agustin Vargas, Thaís Bianca Brandão, Alan Roger Santos-Silva, Ana Carolina Prado-Ribeiro
The dental treatment of patients with oral cavity and oropharyngeal squamous cell carcinoma (OOPSCC) may be challenging for dentists. This study aimed to characterize systemic changes in patients with OOPSCC undergoing dental treatment prior to cancer therapy, with a specific focus on laboratory assessments. The primary objectives included identifying potential adverse events, such as infections or bleeding, resulting from dental procedures. Additionally, the study aimed to correlate baseline patient characteristics with treatment-related toxicities...
April 1, 2024: Dentistry Journal
#20
JOURNAL ARTICLE
Luca Pecoraro, Melissa Zadra, Francesco Cavallin, Silvana Lauriola, Giorgio Piacentini, Angelo Pietrobelli
Children with Down Syndrome (DS) frequently undergo health challenges, including a higher prevalence of overweight and obesity. We aimed to evaluate the impact of dietary and physical advice provided by a specialized pediatrician over two years. In this prospective study, 44 children with DS, aged 2 to 17, underwent outpatient follow-up visits every six months between December 2020 and May 2023. Dietary habits, physical activities, anthropometric data, and laboratory results were recorded at baseline and 2-year follow-up...
March 29, 2024: Diseases (Basel)
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