keyword
https://read.qxmd.com/read/38688741/realizing-high-efficiency-thermoelectric-module-by-suppressing-donor-like-effect-and-improving-preferred-orientation-in-n-type-bi-2-te-se-3
#1
JOURNAL ARTICLE
Yichen Li, Shulin Bai, Yi Wen, Zhe Zhao, Lei Wang, Shibo Liu, Junqing Zheng, Siqi Wang, Shan Liu, Dezheng Gao, Dongrui Liu, Yingcai Zhu, Qian Cao, Xiang Gao, Hongyao Xie, Li-Dong Zhao
Thermoelectric materials have a wide range of application because they can be directly used in refrigeration and power generation. And the Bi2 Te3 stand out because of its excellent thermoelectric performance and are used in commercial thermoelectric devices. However, n-type Bi2 Te3 has seriously hindered the development of Bi2 Te3 -based thermoelectric devices due to its weak mechanical properties and inferior thermoelectric performance. Therefore, it is urgent to develop a high-performance n-type Bi2 Te3 polycrystalline...
April 18, 2024: Science Bulletin
https://read.qxmd.com/read/38669396/the-value-of-thromboelastography-in-evaluating-the-efficacy-of-xueshuantong-combined-with-edaravone-in-the-treatment-of-acute-cerebral-infarction
#2
JOURNAL ARTICLE
Yu Wang, Litao Li, Xiaojie Hu, Liqiu Huang, Zheng Li
To explore the value of thromboelastography (TEG) in evaluating the efficacy of Xueshuantong combined with edaravone for the treatment of acute cerebral infarction (ACI). We retrospectively analyzed the clinical data of 96 patients with ACI treated with Xueshuantong combined with edaravone and monitored by TEG. The correlation between the results of TEG examination and treatment outcomes in patients after treatment was analyzed. After treatment, 65 of 96 patients showed good efficacy and 31 had poor efficacy...
April 26, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38622176/thermoelectric-generator-powered-timepiece-circuit-for-rechargeable-battery-operation
#3
JOURNAL ARTICLE
Sam Methuselah Penumala, A Karmel, G Kanimozhi, Jagriti Khanwalkar
The advent of digital technology has revolutionized the way we keep track of time. Digital watches have become an essential part of our daily lives and provide us with accurate and reliable time measurement. However, battery reliability is a long-standing issue in the digital watch industry. Batteries require frequent replacement and are a major source of waste. To solve this problem, a digital watch that runs on a lithium-polymer battery that is recharged by a voltage generated by a thermoelectric generator (TEG) placed on the hand...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38608654/hypercoagulability-based-on-thromboelastography-is-common-in-dogs-undergoing-adrenalectomy
#4
JOURNAL ARTICLE
Akiko Mitsui, Sydney Rosen, Page Yaxley, Janis Lapsley, Giovanni Tremolada, Laura E Selmic
OBJECTIVE: Thromboelastography (TEG) is a whole blood assay that yields global assessment of hemostasis, as it evaluates clot time, strength, and kinematics of clot formation and lysis. The main objective was to describe preoperative TEG findings in dogs that had an adrenalectomy performed and, secondarily, to describe TEG findings in the dogs with or without hyperadrenocorticism (HAC). ANIMALS: 30 dogs that had preoperative TEG and adrenalectomy performed. METHODS: Medical records between 2018 and 2022 were reviewed...
April 12, 2024: Journal of the American Veterinary Medical Association
https://read.qxmd.com/read/38605827/constitutive-hypercoagulability-in-pediatric-sickle-cell-disease-patients-with-hemoglobin-ss-genotype
#5
JOURNAL ARTICLE
Raizl G Sussman, Joy Mburu, MacGregor Steele, Annie Bang, Jeremy Friedman, Ran Goldman, Melanie Kirby, Margaret L Rand, Victor S Blanchette, Fred G Pluthero, Suzan Williams, Walter H A Kahr
BACKGROUND: Constitutive inflammation and hemostatic activation have been identified as key contributors to the pathophysiology of sickle cell disease (SCD), leading to clinical consequences such as vaso-occlusive crises and stroke. Patients with hemoglobin SS (HbSS) and hemoglobin SC (HbSC) genotypes are reported to have different symptoms, as do patients in steady-state and crisis situations. Differences among these groups remain unclear in pediatric patients. OBJECTIVES: To compare hemostatic activity in HbSS and HbSC pediatric patients during steady state, in crisis, and in clinical follow-up and compare HbSS and HbSC patients with normal healthy children...
March 2024: Research and Practice in Thrombosis and Haemostasis
https://read.qxmd.com/read/38584233/oxidative-desulfurization-of-fuels-using-alcohol-based-dess
#6
JOURNAL ARTICLE
Nisha Saini, Mansi Negi, Pooja Yadav, Rajkumar Singh
The presence of sulfur-containing compounds in fuel oil has become a major global issue due to their release of toxic sulfur dioxide. Hydrodesulfurization is a commonly used method for removing sulfur from fuel. However, new desulfurization techniques have been developed recently as hydrodesulfurization (HDS) is ineffective in removing refractory sulfur, e.g., BT, DBT, 4-MDBT. In this study, a series of deep eutectic solvent (DES) using ChCl, salicylic acid, oxalic acid, citric acid, and adipic acid as hydrogen bond acceptors and MeOH, EtOH, BuOH, EG, DEG, and TEG as hydrogen bond donors on different mole ratios were synthesized and then investigated the efficiency of these DESs in extracting sulfur from model and diesel fuel...
April 8, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38557578/implementation-and-effectiveness-outcomes-of-community-health-advocacy-teams-to-improve-long-lasting-insecticide-net-distribution-and-use-in-six-districts-in-ghana-a-one-group-pre-post-test-study
#7
JOURNAL ARTICLE
Franklin N Glozah, Philip Teg-Nefaah Tabong, Eva Bazant, Emmanuel Asampong, Ruby Hornuvo, Adanna Nwameme, Nana Yaw Peprah, Gloria M Chandi, Philip Baba Adongo, Phyllis Dako-Gyeke
Malaria remains a leading cause of illness and death especially among children and pregnant women in Ghana. Despite the efforts made by the National Malaria Elimination Programme (NMEP), including distribution of Long-Lasting Insecticide Nets (LLINs) to households through periodic Point Mass Distribution (PMD) campaigns and continuous channels (antenatal, schools and postnatal), there is a gap between access and use of LLINs in Ghana. An effective and functional community-based group that would seek to improve the effectiveness of LLIN distribution before, during, after PMD Campaigns and continuous distribution at the community level could help address this gap...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38546342/a-low-bleeding-risk-thrombolytic-agent-citpa5
#8
JOURNAL ARTICLE
Shanli Chen, Sudan Fang, Yang Zhou, Zhiwei Huang, Shujuan Yu, Dan Chen, Zhiyou Wang, Yanyan Xu, Peiwen Liu, Yongkun Li, Wei Lin, Longguang Jiang, Cai Yuan, Mingdong Huang
AIMS: Alteplase is a cornerstone thrombolytic agent in clinical practice, but presents a potential bleeding risk. Stroke patients need pre-screening to exclude hemorrhagic stroke before using Alteplase. In this study, we develop a new thrombolytic agent citPA5, characterized by an enhanced safety profile and minimal bleeding tendency. METHODS AND RESULTS: A clot lysis agent, named citPA5, is developed based on rtPA with point mutations to completely suppress its proteolytic activity in the absence of fibrin...
March 28, 2024: Cardiovascular Research
https://read.qxmd.com/read/38536675/a-novel-method-for-targeted-identification-of-essential-proteins-by-integrating-chemical-reaction-optimization-and-naive-bayes-model
#9
JOURNAL ARTICLE
Wenya Yang, Sai Zou, Hongfeng Gao, Lei Wang, Wei Ni
Targeted identification of essential proteins is of great significance for species identification, drug manufacturing, and disease treatment. It is a challenge to analyze the binding mechanism between essential proteins and improve the identification speed while ensuring the accuracy of the identification. This paper proposes a novel method called EPCRO for identifying essential proteins, which incorporates the chemical reaction optimization (CRO) algorithm and the naive Bayes model to effectively detect essential proteins...
March 27, 2024: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://read.qxmd.com/read/38410602/understanding-the-systemic-effects-of-intrapleural-tpa-and-dnase-by-evaluating-effects-on-coagulation
#10
JOURNAL ARTICLE
Thomas W Marston, Kartikeya Rajdev, Kaeli K Samson, Daniel M Hershberger
BACKGROUND: Complicated parapneumonic effusions and empyemas are common presentations that carry significant morbidity and mortality. Standard therapy includes antibiotics and chest tube placement. Due to the nature of the fluid, it is often difficult to drain completely using a chest tube. As outlined in multiple studies, intrapleural tissue plasminogen activator (tPA) and dornase alfa (DNase) are effective at helping clear these effusions and the avoidance of surgery. Despite research to better understand the effectiveness of the treatment and possible side effects, there continues to be a lack of data on potential systemic effects...
January 30, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38337863/hemostasis-in-pre-eclamptic-women-and-their-offspring-current-knowledge-and-hemostasis-assessment-with-viscoelastic-tests
#11
REVIEW
Christos-Georgios Kontovazainitis, Dimitra Gialamprinou, Theodoros Theodoridis, Georgios Mitsiakos
Pre-eclampsia (PE) is a placenta-mediated disease and remains a major cause of maternal and neonatal mortality and morbidity. As PE develops, normal pregnancy's hypercoagulable balance is disrupted, leading to platelet hyperactivation, excessive pathological hypercoagulability, and perturbed fibrinolysis. This narrative review aims to summarize the current knowledge regarding hemostasis in PE compared with healthy gestation and the potential effects of maternal PE on neonatal hemostasis. Finally, it aims to discuss hemostasis assessments for normal pregnancies and PE, emphasizing the role of viscoelastic tests, namely, thromboelastography (TEG) and thromboelastometry (ROTEM), for monitoring PE-associated hemostatic alterations...
February 5, 2024: Diagnostics
https://read.qxmd.com/read/38335260/aqueous-solution-synthesized-p-type-cu-2-se-0-96-te-0-04-x-i-x-cu-2-o-composite-and-thermoelectric-performance-of-teg-made-of-6-pairs-of-p-leg-cu-2-se-0-96-te-0-02-i-0-02-cu-2-o-composite-and-n-leg-insb-0-94-bi-0-06
#12
JOURNAL ARTICLE
Vinothkumar Lourdhusamy, Immanuel Paulraj, Chia-Jyi Liu
Cu2 Se-based thermoelectric materials exhibit high dimensionless figure of merit ( zT ) values at elevated temperatures (900-1000 K) but relatively lower zT values at intermediate temperatures, approximately 500 K. We synthesized a series of polycrystalline Cu2 Se0.96 Te0.04- x I x /Cu2 O composites (where x = 0.00, 0.01, 0.02, and 0.03) using an energy-efficient synthesis method conducted at room temperature, followed by heat treatment at 923 K for 6 h. X-ray diffraction (XRD) analysis confirmed the monoclinic crystal structure of the α phase...
February 9, 2024: Inorganic Chemistry
https://read.qxmd.com/read/38322976/features-of-thromboelastogram-in-populations-exposed-to-or-transferring-from-high-altitude
#13
JOURNAL ARTICLE
Zhu Huang, Dong-Xin Huang, Yan-Yan Wang, Li-Juan Jiang, Yong-Hua Wang, Jing Dai, Xia Kang, Yi Wen, Si-Yi He
BACKGROUND: Thromboelastogram (TEG) is an effective indicator that monitors the dynamic changes of blood coagulation in real-time. It still remains controversial about the performance and influence of coagulation at high altitude. The present study intends to describe comprehensively the clinical features of TEG in populations exposed to or transferring from high altitude. METHODS: Two groups were recruited in the present study. Group A included young males who worked at high-altitude (4888 m or 5418 m) areas for some time, while Group B included young males who had recently returned from high-altitude (4888 m or 5418 m) areas...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38275857/acoustic-fractional-propagation-in-terms-of-porous-xerogel-and-fractal-parameters
#14
JOURNAL ARTICLE
Maria-Alexandra Paun, Vladimir-Alexandru Paun, Viorel-Puiu Paun
This article portrays solid xerogel-type materials, based on chitosan, TEGylated phenothiazine, and TEG (tri-ethylene glycol), dotted with a large number of pores, that are effectively represented in their constitutive structure. They were assumed to be fractal geometrical entities and adjudged as such. The acoustic fractional propagation equation in a fractal porous media was successfully applied and solved with the help of Bessel functions. In addition, the fractal character was demonstrated by the produced fractal analysis, and it has been proven on the evaluated scanning electron microscopy (SEM) pictures of porous xerogel compounds...
January 22, 2024: Gels
https://read.qxmd.com/read/38201430/subtypes-of-melanomas-associated-with-different-degrees-of-actinic-elastosis-in-conventional-histology-irrespective-of-age-and-body-site-suggesting-chronic-ultraviolet-light-exposure-as-driver-for-lentigo-maligna-melanoma-and-nodular-melanoma
#15
JOURNAL ARTICLE
Konstantin Drexler, Veronika Zenderowski, Laura Schreieder, Kevin Koschitzki, Sigrid Karrer, Mark Berneburg, Sebastian Haferkamp, Dennis Niebel
(1) Background: Ultraviolet (UV) radiation and sunburns are associated with an increased incidence of acquired nevi and melanomas. However, the data are controversial as to whether chronic UV exposure or high intermittent UV exposure is the major carcinogenic factor in melanocytic tumors. In this study, we compared the degree of actinic elastosis (AE) as a surrogate for lifetime UV exposure in nevi and different clinical melanoma subtypes (i.e., superficial spreading melanoma (SSM), nodular malignant melanoma (NMM), acral lentiginous melanoma (ALM), and lentigo maligna melanoma (LMM)) with respect to clinical variables (age, sex, and body site)...
December 19, 2023: Cancers
https://read.qxmd.com/read/38136455/linear-irreversible-thermodynamics-a-glance-at-thermoelectricity-and-the-biological-scaling-laws
#16
JOURNAL ARTICLE
Juan Carlos Chimal-Eguia, Ricardo Teodoro Páez-Hernández, Juan Carlos Pacheco-Paez, Delfino Ladino-Luna
This paper presents so-called thermoelectric generators (TEGs), which are considered thermal engines that transform heat into electricity using the Seebeck effect for this purpose. By using linear irreversible thermodynamics (LIT), it is possible to study the thermodynamic properties of TEGs for three different operating regimes: maximum power output (MPO), maximum ecological function (MEF) and maximum power efficiency (MPE). Then, by considering thermoelectricty, using the correspondence between the heat capacity of a solid and the metabolic rate, and taking the generation of energy by means of the metabolism of an organism as a process out of equilibrium, it is plausible to use linear irreversible thermodynamics (LIT) to obtain some interesting results in order to understand how metabolism is generated by a particle's released energy, which explains the empirically studied allometric laws...
November 23, 2023: Entropy
https://read.qxmd.com/read/38089903/towards-achieving-transnational-research-partnership-equity-lessons-from-implementing-adaptive-platform-trials-in-low-and-middle-income-countries
#17
JOURNAL ARTICLE
Chelsea Modlin, Jeremy Sugarman, Gershom Chongwe, Nancy Kass, Winfred Nazziwa, Jemee Tegli, Prakriti Shrestha, Joseph Ali
BACKGROUND: Use of adaptive clinical trials, particularly adaptive platform trials, has grown exponentially in response to the coronavirus disease (COVID-19) pandemic. Implementation of these trials in low- and middle-income countries (LMICs) has been fostered through the formation or modification of transnational research partnerships, typically between research groups from LMICs and high-income countries (HICs). While these partnerships are important to promote collaboration and overcome the structural and economic disadvantages faced by LMIC health researchers, it is critical to focus attention on the multiple dimensions of partnership equity...
2023: Wellcome Open Research
https://read.qxmd.com/read/37995371/tranexamic-acid-class-i-drug-reduced-and-capped-gold-nanoparticles-as-a-potential-hemostatic-agent-with-enhanced-performance
#18
JOURNAL ARTICLE
Chandan Bhogendra Jha, Chitrangda Singh, Parag Patil, Kuntal Manna, Sweta Singh, Raunak Varshney, R Mathur
External hemostatic agents play a crucial role in stabilising an impaired process during pathological conditions. The idea is to stabilise the in vivo system as soon as possible. This study uses a class I hemostatic drug tranexamic acid as reducing and capping agent for synthesising the gold nanoparticles (Tr-AuNPs). Being the synthetic analogue of lysine and a biologically inspired alkylamine molecule the chemistry can be fine-tuned for stable material which can target the intrinsic and extrinsic hemostatic pathway simultaneously making it a promising for hemostatic applications...
November 23, 2023: Nanotechnology
https://read.qxmd.com/read/37966879/in-vitro-evaluation-of-hyperosmotic-canine-plasma-suitable-for-infusion
#19
JOURNAL ARTICLE
Thomas H Edwards, Michael A Meledeo, Grantham C Peltier, Alice F Henderson, Luis A Pompa, James A Bynum
OBJECTIVE: To determine the characteristics of canine freeze-dried plasma (cFDP) as it is serially diluted with sterile water. DESIGN: In vitro experimental study. SETTING: Government blood and coagulation research laboratory. ANIMALS: cFDP from a commercial manufacturer. INTERVENTIONS: Ten units of cFDP were reconstituted to 100%, 90%, 80%, 70%, 60%, 50%, and 40% of the recommended volume with sterile water...
November 15, 2023: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/37893432/artificial-intelligence-and-neurosurgery-tracking-antiplatelet-response-patterns-for-endovascular-intervention
#20
REVIEW
Khushi Saigal, Anmol Bharat Patel, Brandon Lucke-Wold
Platelets play a critical role in blood clotting and the development of arterial blockages. Antiplatelet therapy is vital for preventing recurring events in conditions like coronary artery disease and strokes. However, there is a lack of comprehensive guidelines for using antiplatelet agents in elective neurosurgery. Continuing therapy during surgery poses a bleeding risk, while discontinuing it before surgery increases the risk of thrombosis. Discontinuation is recommended in neurosurgical settings but carries an elevated risk of ischemic events...
September 25, 2023: Medicina
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