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REVIEW
Lorenzo Andreani, Edoardo Ipponi, Alfio Damiano Ruinato, Tommaso Lupi, Federico Di Sacco, Duccio Volterrani, Luca Coccoli, Rodolfo Capanna
Osteosarcoma (OS) and Ewing sarcoma (ES) represent the pediatric population's most common malignant bone tumors. 18-Fluorodeoxyglucose positron emission tomography has been shown to be effective in both the diagnostic and staging phases of cancer treatment. In recent years, some studies have also explored the possibility that FDG-PET could have a prognostic role.
April 30, 2024: Folia Medica
#2
Shagun, Alex Kim, Victoria Koshevarova, Payam Mohammadinejad, Micah Murphy, Peeyush Bhargava
This case report follows a 66-year-old female who originally presented with malignant melanoma in the left knee and recurrence in the left inguinal region. This prompted a whole body FDG PET/CT scan which showed incidental focal hypermetabolism in the uterus. The diagnosis of endometrial cancer was confirmed at biopsy, and the patient was treated with total abdominal hysterectomy. Melanoma patients are at increased risk of second primary malignancy, and endometrial cancer is a common second primary often diagnosed in cancer survivors...
July 2024: Radiology Case Reports
#3
JOURNAL ARTICLE
Tianhang Li, Qinqin You, Shiwei Zhang, Rushuai Li, Shangxun Xie, Danyan Li, Shuyue Ai, Rong Yang, Hongqian Guo
18 F-FDG PET/MRI shows potential efficacy in the diagnosis of bladder cancer (BLCA). However, the performance of 18 F-FDG PET/MRI in staging and neoadjuvant therapy (NAT) response evaluation for BLCA patients remains elusive. Here, we conduct this study to evaluate the performance of 18 F-FDG PET/MRI and its derived parameters for tumor staging and NAT response prediction in BLCA. Forty BLCA patients were retrospectively enrolled to evaluate the performance of 18 F-FDG PET/MRI in staging and NAT response prediction in BLCA...
May 17, 2024: IScience
#4
JOURNAL ARTICLE
Xuhe Liao, Hongwei Sun, Xueqi Chen, Yan Fan, Jianhua Zhang
Dedifferentiated liposarcoma is an extremely rare and highly malignant tumor. We demonstrated a case of a 75-year-old man with significantly PSMA-avid and mildly FDG uptake-dedifferentiated liposarcoma in the retroperitoneal area. The double-tracer (PSMA and FDG) PET scans could further contribute to differential diagnosis and the following treatment strategy for patients who were suspected with prostate cancer metastases and other malignant tumors simultaneously.
May 1, 2024: Clinical Nuclear Medicine
#5
JOURNAL ARTICLE
Yu Yu, Jing Zhu, Shibiao Sang, Yi Yang, Bin Zhang, Shengming Deng
OBJECTIVE: It is crucially essential to differentially diagnose single-nodule pulmonary metastases (SNPMs) and second primary lung cancer (SPLC) in patients with colorectal cancer (CRC), which has important clinical implications for treatment strategies. In this study, we aimed to establish a feasible differential diagnosis model by combining 18F-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) radiomics, computed tomography (CT) radiomics, and clinical features. MATERIALS AND METHODS: CRC patients with SNPM or SPLC who underwent 18F-FDG PET/CT from January 2013 to July 2022 were enrolled in this retrospective study...
April 1, 2024: Journal of Cancer Research and Therapeutics
#6
JOURNAL ARTICLE
Yash Jain, Archi Agrawal, Amit Joshi, Santosh Menon, Gagan Prakash, Vedang Murthy, Nilendu Purandare, Sneha Shah, Ameya Puranik, Sayak Choudhury, Varun Shukla, Indraja Dev, Kumar Prabhash, Vanita Noronha, Venkatesh Rangarajan
AIM: To evaluate relationship between metabolic PET metabolic parameters and size of the primary tumor, various histopathological subtypes of renal cell carcinoma (RCC) and Fuhrman grade of the tumors. MATERIAL AND METHODS: Retrospective analysis of 93 biopsy-proven RCC patients who underwent pretreatment flourine 18 flourodeoxyglucose PET/computed tomography (18F FDG PET/CT) was performed. Quantitative PET parameters, size of the primary tumor, histopathological subtypes and Fuhrman grades of the tumor were extracted...
April 30, 2024: Nuclear Medicine Communications
#7
JOURNAL ARTICLE
Bin Wang, Xinming Zhao, Yunuan Liu, Zhaoqi Zhang, Xiaoshan Chen, Fenglian Jing, Xiaolin Chen, Yu Hua, Jianqiang Zhao
OBJECTIVE: The objective of this study is to evaluate the effectiveness of 68Ga-FAPI-04 PET/computed tomography (CT) for the diagnosis of primary and metastatic gastric cancer and colorectal cancer lesions as compared with 18F-FDG PET/CT. MATERIALS AND METHODS: Fifty-nine patients who underwent both 18F-FDG and 68Ga-FAPI-04 for initial staging or restaging were enrolled. Histopathological findings and clinical imaging follow-up were used as the reference standard...
April 29, 2024: Nuclear Medicine Communications
#8
JOURNAL ARTICLE
Toshihiko Matsuo, Takehiro Tanaka
To elucidate long-term outcome in primary conjunctival lymphoma, a review was conducted of 31 consecutive patients: 21 men and 10 women with an age range of 28 to 85 (median, 61) years at presentation and follow-up periods ranging from 1 to 19 (median, 7) years. Conjunctival lymphoma was on the right side in 10 patients, on the left side in 12, and on both sides in 9. Upper, lower, or both fornix lesions in 28 patients were all diagnosed as extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), while thick nasal bulbar conjunctival lesions in 3 patients were differently diagnosed as MALT lymphoma, diffuse large B-cell lymphoma, and follicular lymphoma, respectively...
April 30, 2024: Journal of Clinical and Experimental Hematopathology: JCEH
#9
REVIEW
Yaniv Yechiel, Alexandre Chicheportiche, Zohar Keidar, Simona Ben-Haim
Prostate cancer is the most common malignancy in men worldwide, with an estimated 174,650 new cases per year in the United States, and the second cancer-related cause of death, after lung cancer, with 31,620 deaths per year. While the 5 year survival rate for prostate cancer in patients without metastatic spread is nearly 100%, those with distant metastases have 5 year survival rates of approximately 30%. Initial diagnosis and assessment are based on PSA levels, Gleason score (derived from prostate biopsy), and advanced imaging modalities, including prostate MR imaging and PSMA-PET/computed tomography in patients with high-risk features...
April 27, 2024: PET Clinics
#10
JOURNAL ARTICLE
Tiuri E Kroese, Sebastiaan Bronzwaer, Peter S N van Rossum, Sebastian F Schoppman, Pieter R A J Deseyne, Eric van Cutsem, Karin Haustermans, Philippe Nafteux, Melissa Thomas, Radka Obermannova, Hanna R Mortensen, Marianne Nordsmark, Per Pfeiffer, Anneli Elme, Antoine Adenis, Guillaume Piessen, Christiane J Bruns, Florian Lordick, Ines Gockel, Markus Moehler, Cihan Gani, Theodore Liakakos, John V Reynolds, Alessio G Morganti, Riccardo Rosati, Carlo Castoro, Francesco Cellini, Domenico D'Ugo, Franco Roviello, Maria Bencivenga, Giovanni de Manzoni, Mark I van Berge Henegouwen, Maarten C C M Hulshoff, Jolanda van Dieren, Marieke Vollebergh, Johanna W van Sandick, Paul Jeene, Christel Muijs, Marije Slingerland, Francine E M Voncken, Henk Hartgrink, Geert-Jan Creemers, Maurice J C van der Sangen, Grard A P Nieuwenhuijzen, Maaike Berbee, Marcel Verheij, Bas Wijnhoven, Laurens V Beerepoot, Nadia Haj Mohammad, Stella Mook, Jelle P Ruurda, Piotr Kolodziejczyk, Wojciech P Polkowski, Lucjan Wyrwicz, Maria Alsina, Josep Tabernero, Manuel Pera, Tania F Kanonnikoff, Andrés Cervantes, Magnus Nilsson, Stefan Monig, Anna D Wagner, Matthias Guckenberger, Ewen A Griffiths, Elizabeth Smyth, George B Hanna, Sheraz Markar, M Asif Chaudry, Maria A Hawkins, Edward Cheong, Hanneke W M van Laarhoven, Richard van Hillegersberg
INTRODUCTION: The OligoMetastatic Esophagogastric Cancer (OMEC) project aims to provide clinical practice guidelines for the definition, diagnosis, and treatment of esophagogastric oligometastatic disease (OMD). METHODS: Guidelines were developed according to AGREE II and GRADE principles. Guidelines were based on a systematic review (OMEC-1), clinical case discussions (OMEC-2), and a Delphi consensus study (OMEC-3) by 49 European expert centers for esophagogastric cancer...
April 16, 2024: European Journal of Cancer
#11
JOURNAL ARTICLE
Yukinori Okada, Tatsuhiko Zama, Tomohiro Itonaga, Ryuji Mikami, Mitsuru Okubo, Shinji Sugahara, Masahiko Kurooka, Motoki Nakai, Koichiro Abe, Mana Yoshimura, Kazuhiro Saito
OBJECTIVE: To investigate the positron emission tomography/computed tomography (PET/CT) findings of T1/T2N0M0 glottic cancer (hereafter referred to as T1/T2) and dose distribution in radiotherapy. SUBJECTS AND METHODS: We retrospectively collected data from patients diagnosed with T1/T2N0M0 glottic cancer who received radiotherapy. The extent of fluorine-18-fluorodeoxyglucose (18 F-FDG) accumulation in primary tumors, maximum standardized uptake value (SUVmax), total lesion glycolysis (TLG), tumor volume of primary tumors on PET/CT were compared...
2024: Hellenic Journal of Nuclear Medicine
#12
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 27, 2024: Journal for Immunotherapy of Cancer
#13
JOURNAL ARTICLE
Nikola Colic, Ruza Stevic, Mihailo Stjepanovic, Milan Savić, Jelena Jankovic, Slobodan Belic, Jelena Petrovic, Nikola Bogosavljevic, Dejan Aleksandric, Katarina Lukic, Marko Kostić, Dusan Saponjski, Jelena Vasic Madzarevic, Stefan Stojkovic, Maja Ercegovac, Zeljko Garabinovic
Background and Objectives: Lung cancer is the second most common form of cancer in the world for both men and women as well as the most common cause of cancer-related deaths worldwide. The aim of this study is to summarize the radiological characteristics between primary lung adenocarcinoma subtypes and to correlate them with FDG uptake on PET-CT. Materials and Methods: This retrospective study included 102 patients with pathohistologically confirmed lung adenocarcinoma. A PET-CT examination was performed on some of the patients and the values of SUVmax were also correlated with the histological and morphological characteristics of the masses in the lungs...
April 10, 2024: Medicina
#14
REVIEW
Athina C Tsili, George Alexiou, Martha Tzoumpa, Timoleon Siempis, Maria I Argyropoulou
This review aims to compare the diagnostic performance of multidetector CT (MDCT), MRI, including diffusion-weighted imaging, and FDG PET/CT in the detection of peritoneal metastases (PMs) in ovarian cancer (OC). A comprehensive search was performed for articles published from 2000 to February 2023. The inclusion criteria were the following: diagnosis/suspicion of PMs in patients with ovarian/fallopian/primary peritoneal cancer; initial staging or suspicion of recurrence; MDCT, MRI and/or FDG PET/CT performed for the detection of PMs; population of at least 10 patients; surgical results, histopathologic analysis, and/or radiologic follow-up, used as reference standard; and per-patient and per-region data and data for calculating sensitivity and specificity reported...
April 11, 2024: Cancers
#15
JOURNAL ARTICLE
Mark J Roef, Kim van den Berg, Harm J T Rutten, Jacobus Burger, Joost Nederend
Rationale: F18-FDG PET/CT may be helpful in baseline staging of patients with high-risk LARC presenting with vascular tumor deposits (TDs), in addition to standard pelvic MRI and CT staging. Methods: All patients with locally advanced rectal cancer that had TDs on their baseline MRI of the pelvis and had a baseline F18-FDG PET/CT between May 2016 and December 2020 were included in this retrospective study. TDs as well as lymph nodes identified on pelvic MRI were correlated to the corresponding nodular structures on a standard F18-FDG PET/CT, including measurements of nodular SUVmax and SUVmean...
April 22, 2024: Tomography: a Journal for Imaging Research
#16
Zhe Dong, Gao-Yuan Wang, Dong-Yu Dai, Guan-Jie Qin, Ling-Long Tang, Cheng Xu, Jun Ma
No abstract text is available yet for this article.
April 25, 2024: BMC Cancer
#17
JOURNAL ARTICLE
Saskia A Cooke, José S A Belderbos, Bart Reymen, Maarten Lambrecht, Gitte Fredberg Persson, Corinne Faivre-Finn, Edith M T Dieleman, Judi N A van Diessen, Jan-Jakob Sonke, Dirk de Ruysscher
BACKGROUND AND PURPOSE: The ultimate challenge in dose-escalation trials lies in finding the balance between benefit and toxicity. We examined patient-reported outcomes (PROs), including health-related quality of life (HRQoL) in patients with locally advanced non-small cell lung cancer (LA-NSCLC), treated with dose-escalated radiotherapy. MATERIALS AND METHODS: The international, randomised, phase 2 ARTFORCE PET-Boost study (NCT01024829) aimed to improve 1-year freedom from local failure rates in patients with stage II-III NSCLC, with a ≥ 4 cm primary tumour...
April 23, 2024: Radiotherapy and Oncology
#18
JOURNAL ARTICLE
P Cegla, G M Currie, W Cholewinski, M Bryl, M Trojanowski, K Matuszewski, T Piotrowski, R Czepczyński
INTRODUCTION: Positron emission tomography/computed tomography (PET/CT) has an established role in evaluating patients with lung cancer. The aim of this work was to assess the predictive capability of [18 F]Fluorodeoxyglucose ([18 F]FDG) PET/CT parameters on overall survival (OS) in lung cancer patients using an artificial neural network (ANN) in parallel with conventional statistical analysis. METHODS: Retrospective analysis was performed on a group of 165 lung cancer patients (98M, 67F)...
April 24, 2024: Radiography
#19
JOURNAL ARTICLE
Yukako Iritani, Hiroki Kato, Yo Kaneko, Takuma Ishihara, Tomohiro Ando, Masaya Kawaguchi, Hirofumi Shibata, Takenori Ogawa, Yoshifumi Noda, Fuminori Hyodo, Masayuki Matsuo
PURPOSE: This study aimed to assess the imaging features and postoperative natural course of 18 F-fluorodeoxyglucose (FDG) uptake in the cervical muscles after neck dissection. MATERIALS AND METHODS: This study included 83 patients who underwent preoperative and postoperative 18 F-FDG-PET/CT and were diagnosed with head and neck malignancy after neck dissection. Postoperative 18 F-FDG-PET/CT was performed within 5 years after neck dissection. Preoperative and postoperative FDG uptake of the trapezius, sternocleidomastoid, scalene, pectoralis major, and deltoid muscles was visually assessed...
April 25, 2024: Japanese Journal of Radiology
#20
REVIEW
Hisataka Kobayashi, Peter L Choyke
Near infrared photoimmunotherapy (NIR-PIT) is a recently approved cancer therapy for recurrent head and neck cancer. It involves the intravenous administration of an antibody-photoabsorber (IRDye700DX: IR700) conjugate (APC) to target cancer cells, followed 24 h later by exposure to near infrared light to activate cell-specific cytotoxicity. NIR-PIT selectively targets cancer cells for destruction and activates a strong anticancer host immunity. The fluorescent signal emitted by IR700 enables the visualization of the APC in vivo using fluorescence imaging...
April 25, 2024: Japanese Journal of Radiology
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