Sarah Trimpin, Ellen D Inutan, Vincent S Pagnotti, Santosh Karki, Darrell D Marshall, Khoa Hoang, Beixi Wang, Christopher B Lietz, Alicia L Richards, Frank S Yenchick, Chuping Lee, I-Chung Lu, Madeleine Fenner, Sara Madarshahian, Sarah Saylor, Nicolas D Chubatyi, Teresa Zimmerman, Abigail Moreno-Pedraza, Tongwen Wang, Adetoun Adeniji-Adele, Anil K Meher, Hasini Madagedara, Zachary Owczarzak, Ahmed Musavi, Tamara L Hendrickson, Patricia M Peacock, John W Tomsho, Barbara S Larsen, Laszlo Prokai, Vladimir Shulaev, Milan Pophristic, Charles N McEwen
This paper covers direct sub-atmospheric pressure ionization mass spectrometry (MS). The discovery, applications, and mechanistic aspects of novel ionization processes for use in MS that are not based on the high-energy input from voltage, laser, and/or high temperature but on sublimation/evaporation within a region linking a higher to lower pressure and modulated by heat and collisions, are discussed, including how this new reality has guided a series of discoveries, instrument developments, and commercialization...
June 2024: Journal of Mass Spectrometry: JMS