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JOURNAL ARTICLE
The key role of Spain in the traffic of West Nile virus lineage 1 strains between Europe and Africa.
Pilar Aguilera-Sepúlveda, Cristina Cano-Gómez, Rubén Villalba, Vítor Borges, Montserrat Agüero, Daniel Bravo-Barriga, Eva Frontera, Miguel Ángel Jiménez-Clavero, Jovita Fernández-Pinero
BACKGROUND: West Nile Virus (WNV) is a zoonotic arbovirus worldwide spread. Seasonal WNV outbreaks occur in the Mediterranean basin since the late 1990's with ever-increasing incidence. In Southern Spain WNV is endemic, as disease foci - caused by WNV lineage 1 (WNV-L1) strains - occur every year. On the contrary, WNV-L2 is the dominant lineage in Europe, so most European WNV sequences available belong to this lineage, WNV-L1 sequences being still scarce. METHODS: To fill this gap, this study reports the genetic characterisation of 27 newly described WNV-L1 strains, involved in outbreaks affecting wild birds and horses during the last decade in South-Western Spain...
June 5, 2024: Infectious Diseases
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JOURNAL ARTICLE
Bautista Elizalde Acevedo, Valentina Agüero Vera, Silvia Oddo, Delfina De Anchorena, Christine Mohr, Silvia Kochen, Markus Hausmann, Lucía Alba-Ferrara
OBJECTIVE: Temporal lobe epilepsy can disturb eloquent areas, affecting language. We applied a visually-mediated task to measure lateralization of language recognition in drug-resistant temporal lobe epilepsy. METHOD: Patients with left ( n = 26), right ( n = 28) temporal lobe epilepsy and controls ( n = 30) were administered the translingual lexical decision task. We performed repeated measures analyses of variance, with the visual half-field as an intrasubject factor and the group as an intersubject factor...
May 30, 2024: Neuropsychology
#3
JOURNAL ARTICLE
María Iglesias-Caballero, Vicente Mas, Sonia Vázquez-Morón, Mónica Vázquez, Sara Camarero-Serrano, Olga Cano, Concepción Palomo, María José Ruano, Cristina Cano-Gómez, José Antonio Infantes-Lorenzo, Albert Campoy, Montserrat Agüero, Francisco Pozo, Inmaculada Casas
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects various mammalian species, with farmed minks experiencing the highest number of outbreaks. In Spain, we analyzed 67 whole genome sequences and eight spike sequences from 18 outbreaks, identifying four distinct lineages: B.1, B.1.177, B.1.1.7, and AY.98.1. The potential risk of transmission to humans raises crucial questions about mutation accumulation and its impact on viral fitness. Sequencing revealed numerous not-lineage-defining mutations, suggesting a cumulative mutation process during the outbreaks...
May 17, 2024: International Journal of Molecular Sciences
#4
MULTICENTER STUDY
Laura Quezada-Acuña, Solange Parra-Soto, Samuel Durán-Agüero, Yadira Morejón-Terán, Luisa Pérez-Ocampo, Luis Miguel Becerra-Granados, Israel Ríos-Castillo, Gloria Prada-Gómez, Mónica Ramos de Ixtacuy, Roxana Carla Fernández-Condori, María Celeste Nessier, Ana Guerrero-Gómez, Laura González, Edna J Nava-González, José Luis Moya-Osorio
BACKGROUND: The pandemic of coronavirus disease 2019 (COVID-19) pandemic confinement has an impact on stress levels, which causes changes in food purchase and consumption behaviors. The objective of this study is to associate food purchase prioritization with stress level during the COVID-19 pandemic confinement. METHODS: Multicenter, observational and cross-sectional study, an online questionnaire that included data on sociodemographic variables, stress factors and food purchase prioritization was disseminated through digital platforms and social networks...
June 2024: Clinical Nutrition ESPEN
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JOURNAL ARTICLE
Rosa Montesinos, Belen Custodio, Marco Malaga, Diego Chambergo-Michilot, Graciet Verastegui-Aranda, Katherine Agüero, Juan Alejos-Zirena, Luis Andamayo-Villalba, Wendy Seminario G, Nilton Custodio
INTRODUCTION: People caring of individuals with dementia are prone to suffering from burden. Behavioral and psychological symptoms of dementia (BPSD) may have an impact on caregiver burden. In Latin American countries there is lack of research on caregiver burden. We aimed to determine which BPSD have the greatest impact on caregiver burden among Peruvian patients with dementia; and to compare the effects of BPSD on caregiver burden across different types of dementia. METHODS: Cross-sectional study of 231 patients living with Alzheimer's dementia (AD), behavioral variant frontotemporal dementia (bvFTD), dementia with Lewy bodies (DLB) and vascular dementia (VD), and their caregivers attended in a Peruvian memory clinic...
May 20, 2024: Dementia and Geriatric Cognitive Disorders
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JOURNAL ARTICLE
Karn Imwattana, Blanka Aguero, Marta Nieto-Lugilde, Aaron Duffy, Juan Jaramillo-Chico, Kristian Hassel, Olga Afonina, Paul Lamkowski, A Jonathan Shaw
PREMISE: Shared geographical patterns of population genetic variation among related species is a powerful means to identify the historical events that drive diversification. The Sphagnum capillifolium complex is a group of closely related peat mosses within the Sphagnum subgenus Acutifolia and contains several circumboreal species whose ranges encompass both glaciated and unglaciated regions across the northern hemisphere. In this paper, we (1) inferred the phylogeny of subg. Acutifolia and (2) investigated patterns of population structure and genetic diversity among five circumboreal species within the S...
May 19, 2024: American Journal of Botany
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JOURNAL ARTICLE
Felipe Silva, Gonzalo Latorre, Patricio Medel, Miguel Bustamante, Isabella Montero, Camila Robles, Eitan Dukes, Francisca Martinez, María Victoria Binder, Javier Uribe, Diego Reyes, Marcela Bittner, Marisol Sirhan, Manuel Espinoza, Eduardo Fuentes-López, Roberto Candia, Carlos Agüero, José Ignacio Vargas, Alberto Espino, Arnoldo Riquelme
UNLABELLED: Latin America presents a high prevalence of Helicobacter pylori(Hp) infection. Between1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decreasein this infection. Updating the frequency of Hp is crucial due to its associated health impact. OBJECTIVE: Our objective was to describe the trend in Hp infection in patients undergoingambulatory esophagogastroduodenoscopy (EGD) in a Chilean population. MATERIALS AND METHODS: A retrospective observational study was conducted on patients over 18 years old who attended a first EGD with a rapid urease test between 2010-2020...
2024: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
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JOURNAL ARTICLE
Arturo Elías-Domínguez, Juan F J Alvarado, Fernando Pérez-Villaseñor, Arturo Ortíz-Arroyo, Ángel Castro-Agüero, Friné López-Medina, Dulce Y Medina-Velázquez
In this work, the vapor-liquid-liquid equilibrium (VLLE) of the water/ n -pentane, water/ n -hexane, water/ n -octane, and water/ n -decane binary systems is calculated by computer simulation using the NVT-Gibbs ensemble (in the version of three simulation boxes) combined with the configurational bias Monte Carlo method. The combination of both methods, the molecular potential models used, and the simulation details allowed us to calculate the triphasic equilibrium properties of the systems studied: the densities of the three phases in equilibrium, their compositions, and potential energies...
May 10, 2024: Journal of Physical Chemistry. B
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JOURNAL ARTICLE
Alice Fusaro, Bianca Zecchin, Edoardo Giussani, Elisa Palumbo, Montserrat Agüero-García, Claudia Bachofen, Ádám Bálint, Fereshteh Banihashem, Ashley C Banyard, Nancy Beerens, Manon Bourg, Francois-Xavier Briand, Caroline Bröjer, Ian H Brown, Brigitte Brugger, Alexander M P Byrne, Armend Cana, Vasiliki Christodoulou, Zuzana Dirbakova, Teresa Fagulha, Ron A M Fouchier, Laura Garza-Cuartero, George Georgiades, Britt Gjerset, Beatrice Grasland, Oxana Groza, Timm Harder, Ana Margarida Henriques, Charlotte Kristiane Hjulsager, Emiliya Ivanova, Zygimantas Janeliunas, Laura Krivko, Ken Lemon, Yuan Liang, Aldin Lika, Péter Malik, Michael J McMenamy, Alexander Nagy, Imbi Nurmoja, Iuliana Onita, Anne Pohlmann, Sandra Revilla-Fernández, Azucena Sánchez-Sánchez, Vladimir Savic, Brigita Slavec, Krzysztof Smietanka, Chantal J Snoeck, Mieke Steensels, Vilhjálmur Svansson, Edyta Swieton, Niina Tammiranta, Martin Tinak, Steven Van Borm, Siamak Zohari, Cornelia Adlhoch, Francesca Baldinelli, Calogero Terregino, Isabella Monne
Since 2016, A(H5Nx) high pathogenic avian influenza (HPAI) virus of clade 2.3.4.4b has become one of the most serious global threats not only to wild and domestic birds, but also to public health. In recent years, important changes in the ecology, epidemiology, and evolution of this virus have been reported, with an unprecedented global diffusion and variety of affected birds and mammalian species. After the two consecutive and devastating epidemic waves in Europe in 2020-2021 and 2021-2022, with the second one recognized as one of the largest epidemics recorded so far, this clade has begun to circulate endemically in European wild bird populations...
2024: Virus Evolution
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JOURNAL ARTICLE
Valentina Camargo-Herrera, Giovanny Castellanos, Nelson Rangel, Guillermo Antonio Jiménez-Tobón, María Martínez-Agüero, Milena Rondón-Lagos
Chromosomal instability (CIN), defined by variations in the number or structure of chromosomes from cell to cell, is recognized as a distinctive characteristic of cancer associated with the ability of tumors to adapt to challenging environments. CIN has been recognized as a source of genetic variation that leads to clonal heterogeneity (CH). Recent findings suggest a potential association between CIN and CH with the prognosis of BC patients, particularly in tumors expressing the epidermal growth factor receptor 2 (HER2+)...
April 19, 2024: International Journal of Molecular Sciences
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JOURNAL ARTICLE
Fernando Aldana-Salazar, Nelson Rangel, María José Rodríguez, César Baracaldo, María Martínez-Agüero, Milena Rondón-Lagos
In the department of Boyacá, Colombia, agriculture stands as one of the primary economic activities. However, the escalating utilization of pesticides within this sector has sparked concern regarding its potential correlation with elevated risks of genotoxicity, chromosomal alterations, and carcinogenesis. Furthermore, pesticides have been associated with a broad spectrum of genetic polymorphisms that impact pivotal genes involved in pesticide metabolism and DNA repair, among other processes. Nonetheless, our understanding of the genotoxic effects of pesticides on the chromosomes (as biomarkers of effect) in exposed farmers and the impact of genetic polymorphisms (as susceptibility biomarkers) on the increased risk of chromosomal damage is still limited...
April 10, 2024: International Journal of Molecular Sciences
#12
JOURNAL ARTICLE
Rodrigo Cruz-Bautista, Augusto Zelarayan-Agüero, Beatriz Ruiz-Villafán, Adelfo Escalante-Lozada, Romina Rodríguez-Sanoja, Sergio Sánchez
The Streptomyces genus comprises Gram-positive bacteria known to produce over two-thirds of the antibiotics used in medical practice. The biosynthesis of these secondary metabolites is highly regulated and influenced by a range of nutrients present in the growth medium. In Streptomyces coelicolor, glucose inhibits the production of actinorhodin (ACT) and undecylprodigiosin (RED) by a process known as carbon catabolite repression (CCR). However, the mechanism mediated by this carbon source still needs to be understood...
April 24, 2024: Applied Microbiology and Biotechnology
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JOURNAL ARTICLE
Clara Bianquis, Sebastian Leiva Agüero, Chloé Cantero, Alejandro Golfe Bonmatí, Jessica González, Xinxin Hu, Thomas Lacoste-Palasset, Alana Livesey, Raquel Guillamat Prats, Grgur Salai, Dominic L Sykes, Sile Toland, Cristiano van Zeller, Pedro Viegas, Ana Luisa Vieira, Stavroula Zaneli, Christian Karagiannidis, Christoph Fisser
Early career members of Assembly 2 (Respiratory Intensive Care) attended the 2023 European Respiratory Society International Congress in Milan, Italy. The conference covered acute and chronic respiratory failure. Sessions of interest to our assembly members and to those interested in respiratory critical care are summarised in this article and include the latest updates in respiratory intensive care, in particular acute respiratory distress syndrome and mechanical ventilation.
March 2024: ERJ Open Research
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JOURNAL ARTICLE
Juliana Pennone, Natasha Fioretto Aguero, Daniel Marczuk Martini, Luis Mochizuki, Alexandre Alarcon do Passo Suaide
The elderly population is growing rapidly in the world and falls are becoming a big problem for society. Currently, clinical assessments of gait and posture include functional evaluations, objective, and subjective scales. They are considered the gold standard to indicate optimal mobility and performance individually, but their sensitivity and specificity are not good enough to predict who is at higher risk of falling. An innovative approach for fall prediction is the machine learning. Machine learning is a computer-science area that uses statistics and optimization methods in a large amount of data to make outcome predictions...
2024: PloS One
#15
JOURNAL ARTICLE
Gabriela Muñoz, Vanessa Mendieta, Mauricio Ulloa, Belén Agüero, Cristian G Torres, Lucas Kruger, Victor Neira
In January 2023, an active surveillance initiative was undertaken in the South Shetland Islands, Antarctica, with the specific objective of ascertaining evidence for the presence of avian influenza, and specifically the highly pathogenic avian influenza virus subtype H5N1 (HPAIV H5N1). The investigation encompassed diverse locations, including Hanna Point (Livingston Island), Lions Rump (King George Island), and Base Escudero (King George Island), with targeted observations on marine mammals (southern elephant seals), flying birds (the kelp gull, snowy sheathbill and brown skua), and penguins (the chinstrap penguin and gentoo penguin)...
March 26, 2024: Animals: An Open Access Journal From MDPI
#16
JOURNAL ARTICLE
David Aguero, Scott D Nelson
No abstract text is available yet for this article.
April 2024: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
#17
JOURNAL ARTICLE
Miguel A Adami, Marcelo Bertellotti, María Laura Agüero, Martin G Frixione, Verónica L D'Amico
The increasing human population and associated urban waste pose a significant threat to wildlife. Our study focused on the Kelp gull (Larus dominicanus), known for opportunistic feeding in anthropogenic areas, particularly urban landfills. We assessed the physiological status of Kelp gulls at a landfill and compared it with gulls from a protected natural site. Results indicate that gulls from the anthropogenic site exhibited lower levels of key physiological parameters linked to diet, including triglycerides, total proteins, uric acid, plasmatic enzyme activity, body condition index, and leukocyte count, in comparison to their counterparts from the natural site...
April 5, 2024: Marine Pollution Bulletin
#18
JOURNAL ARTICLE
Stephanie Novoa-Sanzana, José Moya-Osorio, Yadira Morejón Terán, Israel Ríos-Castillo, Luis Miguel Becerra Granados, Gloria Prada Gómez, Mónica Ramos de Ixtacuy, Roxana Carla Fernández Condori, María Celeste Nessier, Ana Guerrero Gómez, Laura González-Céspedes, Edna J Nava-González, Luisa Pérez Ocampo, Adriana Nathaly Castillo-Albarracín, Samuel Durán-Agüero
OBJECTIVE: To understand the association of food insecurity with sociodemographic factors in a sample population in Latin America during the COVID-19 pandemic. METHODS: This was a multicenter cross-sectional study conducted in 10 countries in Latin America using an online survey through various digital platforms from October 14, 2020 to February 15, 2021. Statistical analysis of data was performed by applying descriptive statistics, chi-square test, and logistic regression analysis...
2024: Pan American Journal of Public Health
#19
JOURNAL ARTICLE
Elora Valderas-García, Verónica Castilla-Gómez de Agüero, Laura González Del Palacio, Giulio Galli, Nerea Escala, Marta Ruiz-Somacarrera, Marta González-Warleta, Esther Del Olmo, Rafael Balaña-Fouce, María Martínez-Valladares
BACKGROUND: Control of the zoonotic food-borne parasite Fasciola hepatica remains a major challenge in humans and livestock. It is estimated that annual economic losses due to fasciolosis can reach US$3.2 billion in agriculture and livestock. Moreover, the wide distribution of drug-resistant parasite populations and the absence of a vaccine threaten sustainable control, reinforcing the need for novel flukicides. METHODS: The present work analyses the flukicidal activity of a total of 70 benzimidazole derivatives on different stages of F...
April 3, 2024: Parasites & Vectors
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JOURNAL ARTICLE
Rubén Villalba, Cristina Tena-Tomás, María José Ruano, Marta Valero-Lorenzo, Ana López-Herranz, Cristina Cano-Gómez, Montserrat Agüero
The African horse sickness virus (AHSV) belongs to the Genus Orbivirus, family Sedoreoviridae, and nine serotypes of the virus have been described to date. The AHSV genome is composed of ten linear segments of double-stranded (ds) RNA, numbered in decreasing size order (Seg-1 to Seg-10). Genome segment 2 (Seg-2) encodes outer-capsid protein VP2, the most variable AHSV protein and the primary target for neutralizing antibodies. Consequently, Seg-2 determines the identity of the virus serotype. An African horse sickness (AHS) outbreak in an AHS-free status country requires identifying the serotype as soon as possible to implement a serotype-specific vaccination program...
March 20, 2024: Viruses
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