Ariel Israel, Alejandro A Schäffer, Matitiahu Berkovitch, David J Ozeri, Eugene Merzon, Ilan Green, Avivit Golan-Cohen, Eytan Ruppin, Shlomo Vinker, Eli Magen
INTRODUCTION: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked enzymatic disorder that is particularly prevalent in Africa, Asia, and the Middle East. This study aimed to assess the long-term health risks associated with G6PD deficiency. METHODS: A retrospective cohort study was conducted using data from a national healthcare provider in Israel (Leumit Health Services). A total of 7,473 G6PD-deficient individuals were matched with 29,892 control subjects in a 1:4 ratio, based on age, gender, socioeconomic status, and ethnic groups...
2023: Frontiers in Immunology