Pranav Bhagirath, Fernando O Campos, Hassan A Zaidi, Zhong Chen, Mark Elliott, Justin Gould, Michiel J B Kemme, Arthur A M Wilde, Marco J W Götte, Pieter Postema, Anton J Prassl, Aurel Neic, Gernot Plank, Christopher A Rinaldi, Martin J Bishop
BACKGROUND: Implantable cardiac defibrillator (ICD) implantation can protect against sudden cardiac death (SCD) after a myocardial infarction. However, improved risk stratification for device requirement is still needed. OBJECTIVE: To improve assessment of post-infarct ventricular electro-pathology and prediction of appropriate ICD therapy by combining late gadolinium enhancement (LGE) and advanced computational modelling. METHODS: ADAS LV and custom-made software was used to generate 3D patient-specific ventricular models in a prospective cohort of post-infarct patients (n=40) having undergone LGE imaging pre-ICD implantation...
April 24, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society