Ignacio Buenrostro-Rubio, José Antonio Silva-Villaseñor, Avi William Hatami-Blechner, Juan J Salazar-Del Valle, Norma Alejandra Vázquez-Cárdenas, Lilia Patricia Bustamante-Montes, Rafael González-Alvarez
Toxic epidermal necrolysis (TEN) is an extremely rare condition characterized by separation of dermoepidermal junctions, necrosis, and subsequent detachment of the epidermis over large cutaneous areas. TEN can emerge after exposure to certain medications such as allopurinol, aromatic anticonvulsants, NSAIDs, nevirapine, and antibacterial sulfonamides. There is no standard protocol for TEN, and the therapy of choice varies from one patient to another. Some of these therapies include silver-releasing wraps/dressings, glucocorticoids, antibodies to inhibit Fas-mediated keratinocyte apoptosis, and cyclosporine A...
September 23, 2019: Drug Safety—Case Reports