Johannes Zipperle, Johannes Oesterreicher, Matthias Hackl, Teresa Lara Krammer, Helena Thumfart, Madhusudhan Reddy Bobbili, Marion Wiegele, Johannes Grillari, Marcin F Osuchowski, Herbert Schöchl, Wolfgang Holnthoner, Christoph J Schlimp, Judith Schiefer, Marco Valerio Pesce, Stefan Ulbing, Johannes Gratz
Extracellular vesicles (EVs) represent nanometer-sized, subcellular spheres, that are released from almost any cell type and carry a wide variety of biologically relevant cargo. In severe cases of coronavirus disease 2019 (COVID-19) and other states of systemic pro-inflammatory activation, EVs, and their cargo can serve as conveyors and indicators for disease severity and progression. This information may help distinguish individuals with a less severe manifestation of the disease from patients who exhibit severe acute respiratory distress syndrome (ARDS) and require intensive care measures...
November 30, 2023: Intensive Care Medicine Experimental