Min Xiong, Huangwen Lai, Chuanhong Yang, Weiyi Huang, Jian Wang, Xiaoyan Fu, Qinglian He
OBJECTIVE: Oxidative damage is a critical role which involves hearing loss induced by impulse noise. That exogenous antioxidant agents reduce noise induced hearing loss (NIHL) has been well demonstrated in both animal studies and clinical practices. Choosing a stronger and more effective antioxidant is very important for treatment of NIHL. Vitamin E, α-lipoic acid, and radix astragali are the most commonly used anti-oxidants for cochlear oxidative damage from acoustic trauma. In this study, the protective effects of radix astragali, α-lipoic acid, and vitamin E on acute acoustic trauma are investigated...
2012: Clinical Medicine Insights. Ear, Nose and Throat