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Clinical Medicine Insights. Ear, Nose and Throat

Rong-San Jiang, Wen-Jiun Lin
Objective: In this work, our aim was to measure the taste function of healthy Taiwanese adults using 2 commonly used taste tests. Methods: The taste function of 102 healthy Taiwanese adults was evaluated using the whole-mouth suprathreshold taste test and the taste quad test. In the whole-mouth taste test, 5 concentrations of sweet, bitter, sour, and salty solutions were sipped and swished in the mouth twice in a counterbalanced order. A total of 40 tests were done to give a maximum score of 40 for correct quality identification of tastant solutions...
2019: Clinical Medicine Insights. Ear, Nose and Throat
J Alexander de Ru, Boris Filipovic, Jonathan Lans, Erwin L van der Veen, Peter Jfm Lohuis
Entrapment neuropathy is a known cause of neurological disorders. In the head and neck area, this pathophysiological mechanism could be a trigger for headache. Over the last few decades, injection of botulinum toxin type A in the muscles that are causing the compression as well as surgical decompression have proved to be effective treatment methods worldwide for large numbers of patients with daily headaches. In particular the entrapment of the supraorbital nerves in the glabellar musculature and the occipital nerves in the neck musculature are triggers for headache disorders for which many patients are still seeking an effective treatment...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Akshaya Rangarajan, Jasmine Lydia Selvaraj, Divya Perumal Santhanam
Objective: Voice serves as an identity and is one of the primary requisites of an individual, especially for singers who are extensive professional voice users with greater vulnerability to voice disorders. The aim of this study is to translate and validate the Tamil version of Voice-Related Quality of Life (T-VRQOL), a self-rating questionnaire that estimates the influence of voice disorders on quality of life. The study also intends to compare the T-VRQOL scores in singers (with and without voice complaint) and non-singers, and to correlate T-VRQOL and the Tamil Singing Voice Handicap Index-10 (TSVHI-10)...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Jeffrey Michael Singh, Carl Bernard Shermetaro
Background: Kikuchi-Fujimoto Disease (KFD), also known as Histiocytic Necrotizing Lymphadenitis, is a rare cause of prolonged cervical lymphadenopathy in both the pediatric and adult populations. It was first reported in Japan in 1972, and since, this disease has been described worldwide, although most cases have been reported in Asia. The etiology of KFD is not fully understood, although there are 2 theories that are described in detail in this review. Kikuchi-Fujimoto Disease typically follows a benign course, with resolution of the lymphadenopathy within 6 months...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Marisa A Ryan, Tracy Cheng, David S Yoo, Samuel R Fisher
Objectives: We aim to increase awareness of pleomorphic mantle cell lymphoma as a rare, but aggressive form of lymphoma with propensity for recurrence in secondary locations. Methods: We report the case of a 70-year-old man who presented with chronic post-nasal drainage, dysphagia, and voice changes caused by a tongue base mass. Results: Partial excision and pathology showed a pleomorphic mantle cell lymphoma, and radiation treatment was completed...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Rebecca Heidrich Thoen Ribeiro, Fernando Ambros Ribeiro, Romeu Paulo Martins Silva, Miguel Júnior Sordi Bortolini, Mario da Silva Garrote-Filho, Nilson Penha-Silva
Objective: The objective of this study was to evaluate and correlate hematologic indices, vitamin B12 levels, and depression in patients with suspected laryngopharyngeal reflux (LPR) treated with proton pump inhibitor (PPI). Methods: This was a prospective study with a population (n = 23) consisted of patients with suspected LPR and treated with 2 daily doses of Omeprazole 40 mg (80 mg or full dose). The study volunteers performed a complete blood count and vitamin B12 dosage before and after 3 and 6 months of treatment, as well as depression screening using the Center of Epidemiologic Studies-Depression (CES-D) questionnaire before and after 6 months of treatment...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Abdullah A Alatar, Yazeed A AlSuliman, Maha S Alrajhi, Fahad S Alfawwaz
Background: Pneumosinus dilatans (PSD) is a rare pathological paranasal sinus expansion. This condition is usually symptomatic or cosmetically apparent, requiring surgical intervention. Multiple hypotheses have been postulated as to the cause of this condition; however, the precise cause and pathogenesis remain obscure. Case report and Methods: An 11-year-old boy presented with right eye bulging and was subsequently found to have PSD of the maxillary sinus. A search was conducted of the PubMed electronic database, using the keywords "pneumosinus dilatans," "pneum(oco)ele," "pneum(oc)ele," "pneum(atoco)ele," and "air cyst...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Philippe Charlier, Philippe Froesch, Nadia Benmoussa, Stéphane Morin, Anaïs Augias, Yves Ubelmann, Raphaël Weil, Soizic Morin, François Straub, Saudamini Deo
The supposed relics of "Mary-Magdalene" are preserved in Provence (France) in an ancient tradition. They consist of a dry skull and a lock of hair. For the first time, they were officially subjected to an extensive medico-surgical examination by photogrammetry, high-magnification binocular lenses, scanning electron microscope, and energy-dispersive X-ray elemental analysis, to propose a full computer-aided facial reconstruction. The preliminary results are presented here.
2019: Clinical Medicine Insights. Ear, Nose and Throat
Francesco Scaglione, Orlando Petrini
Background: Upper and lower respiratory tract infections are common conditions for which medical advice is sought, and their management relies on the use of prescription and over-the-counter (OTC) medicines. Ambroxol, bromhexine, carbocysteine, erdosteine, N -acetyl cysteine (NAC), and sobrerol are mucoactive agents for which clinical trials have been conducted, have been awarded well-established status by regulatory authorities, and are available as OTC or prescription products. Objective: To briefly review the evidence-based efficacy and safety of these substances in the therapy of upper respiratory airways infections...
2019: Clinical Medicine Insights. Ear, Nose and Throat
Christine M Kim, Michael A Holliday, Kenneth A Newkirk
Objectives: This study aimed to document and describe a case of a laryngeal pilar cyst and to review the literature. Methods: We describe the case of a 65-year-old woman with a laryngeal pilar cyst presenting with occasional ear pain and positional dyspnea, with imaging studies suggesting external/internal laryngocele. We also review the existing clinical literature. Results: Pilar cysts are adnexal skin lesions most commonly found in the scalp of elderly women...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Syeda Beenish Bareeqa, Syed Ijlal Ahmed
Chronic suppurative otitis media is an inflammatory condition characterized by disruption of tympanic membrane and aural discharge. It is one of the most incidental conditions in head and neck. There has been a substantial debate about the therapeutic approach for some decades now. From review of past medical literature, it was evident that culture and sensitivity is essential in eradicating the causative organism. However, the cost-effectiveness is a major concern for low-income population. Due to such concern, empirical therapy has proved to be a suitable therapeutic approach since commonly found organisms are highly sensitive to routine antibiotics...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Changxing Liu, Guy Talmor, Garren Mi Low, Tiffany V Wang, Daljit S Mann, Uttam K Sinha, Niels C Kokot
Introduction: Human papillomavirus (HPV)-positive and HPV-negative oropharyngeal squamous cell carcinomas (OPSCCs) are 2 distinct cancers, with HPV-positivity conferring a better prognosis. Smoking status is a complicating factor for both patient populations. There have been scattered literature that have reported on incomplete information regarding the profiles of their patient population. Details including age and sex distributions, TNM staging, histology grading, recurrence time and types, death rates, and the direct causes of deaths have been reported incompletely in the literature...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Laishyang Melody Ouyoung, Brenda Capobres Villegas, Changxing Liu, Guy Talmor, Uttam K Sinha
Background: Menstruation-related hormonal alteration can be detrimental to the professional singing voice of women. Resonance Voice Therapy (RVT) has been proven to improve vocal production. However, no research to date has been conducted examining the subjective, acoustic, and stroboscopic effects of RVT on professional female singers having premenstrual or postmenopausal voice disorders. Aim: The aim of this study is to compare the vocal effects of RVT with a control cervical-thoracic intervention in healthy female singers during the premenstrual phase as well as in postmenopausal singers and to evaluate which intervention will allow singers to improve vocal performance regardless of changes in hormonal status...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Rong-San Jiang, Wan-Chun Huang, Kai-Li Liang
Objective: The purpose of this study was to investigate the characteristics of this unique form of rhinosinusitis. Methods: Ninety-one patients with sinus fungus balls were evaluated for clinical characteristics. Nasal tissues obtained from 38 patients with sinus fungus ball, along with 26 controls were used for histopathological, cytokines/chemokines, western blotting, and genetic analyses. Results: Patients with fungus balls had significantly more females and their age was older...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Johanna Diplan, Paola Cavallo, Seyla de Los Santos
Schwannoma corresponds to a benign neurogenic tumor, derived from neural crest cells. It accounts for approximately 5% of all benign soft tissue tumors. These are the most common cause of peripheral nerve neoplasms of the oral cavity and oropharynx representing 1%. Isolated or solitary neurofibromas of the oral cavity usually involve the tongue or the labial mucosa. They appear as soft, painless, slow-growing masses that are tender to depression or palpation. The case of a 40-year-old woman is studied because of the presence of painless swelling, slow, and progressive growth of the oral language...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Mariia Karppinen, Atte Sjövall, Tuula Pelkonen, Luis Bernardino, Irmeli Roine, Anne Pitkäranta, Antti A Aarnisalo, Päivi Nevalainen, Leena Lauronen
Objective: To assess the role of single and repeated auditory brain stem response (ABR) in predicting mortality and severe neurological injury among children having bacterial meningitis (BM) in Luanda, Angola. Methods: The morphology of ABR traces of 221 children (aged 2 months to 12 years) from admission day was analyzed and compared with age-matched normative data. Absence and delay of traces were compared with mortality and mortality or severe neurological injury in subgroup analyses...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Henya Sandhaus, Philip G Chen
Introduction: Functional endoscopic sinus surgery is a complex procedure used by otorhinolaryngologists to treat a host of nasal sinus pathologies. Due to the involved nasal anatomy and the nature of the procedure, teaching residents to use an endoscope is challenging. Simulation labs have been helpful but intraoperative instruction can still present difficulty in communication between resident and attending physicians during the teaching process. The purpose of this is to hypothesize a method of teaching intraoperatively that can be used supplemental to or independently of virtual reality teaching...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Maisam Abbas Onali, Syeda Beenish Bareeqa, Sadaf Zia, Syed Ijlal Ahmed, Asneha Owais, Ahmad Nawaz Ahmad
Background: One of the prevailing otologic infections in our country is chronic suppurative otitis media, especially the tubotympanic type for which various treatment protocols are followed. Usually, oral and topical antibiotics (mainly quinolones) are given alone or in combination. There is a lack of consensus as to whether topical drops alone are effective or a combined oral and systemic therapy should be prescribed. In our study, we have attempted to observe the efficacy of empirical therapy with combined ciprofloxacin versus topical drops only in patients with tubotympanic chronic suppurative otitis media for control of infection...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Suvi Renkonen, Antti A Mäkitie, Leif Bäck
Objectives: Benign enlargement of the lingual tonsils due to various causes may cause symptoms that warrant treatment. Conventional lingual tonsillectomy remains a challenging procedure, and there is no established standard procedure. We aimed to review the patients receiving different methods of lingual tonsil surgery for various indications at our institute. Methods: Retrospective clinical data on all patients with an ablative operation of the tongue base during the 8-year period between 2007 and 2014 at the Helsinki University Hospital, Helsinki, Finland, were reviewed...
2018: Clinical Medicine Insights. Ear, Nose and Throat
Issam Saliba, Valérie Sabbah, Jackie Bibeau Poirier
Objective: To compare audiometric results between the standard total ossicular replacement prosthesis (TORP-S) and a new fat interposition total ossicular replacement prosthesis (TORP-F) in pediatric and adult patients and to assess the complication and the undesirable outcome. Study design: This is a retrospective study. Methods: This study included 104 patients who had undergone titanium implants with TORP-F and 54 patients who had undergone the procedure with TORP-S between 2008 and 2013 in our tertiary care centers...
2018: Clinical Medicine Insights. Ear, Nose and Throat
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