Çağlar Ünal, Tolga Özmen, Ahmet Serkan İlgün, Çetin Ordu, Enver Özkurt, Naziye Ak, Gül Alço, Zeynep Erdoğan İyigün, Sevgi Kurt, Tomris Duymaz, Mehmet Alper Öztürk, Filiz Elbüken Çelebi, Kanay Yararbaş, Gürsel Soybir, Fatma Aktepe, Vahit Özmen
BACKGROUND: The minichromosome maintenance protein-2 (MCM-2) is a more sensitive proliferation marker than Ki-67. This study aimed to evaluate the relationship between MCM-2 and Oncotype DX recurrence score (ODX-RS) and determine an MCM-2 cutoff value in high-risk patients according to TAILORx risk categorization. METHODS: Hormone receptor (HR) positive HER-2 negative early-stage breast cancer patients (pT1-2, pN0-N1, M0) who had ODX-RS were included in the study...
2023: Breast Cancer: Targets and Therapy