Fateme Nazary Abrbekoh, Nasrin Valizadeh, Ayla Hassani, Hakime Ghale, Soltan Ali Mahboob, Reza Rahbarghazi, Ali Baradar Khoshfetrat, Mahdi Madipour
Introduction: Here, we monitored the cytocompatibility of scaffolds consisting of poly (glycerol sebacate) (PGS) coated with collagen (Col) for endothelial cell activity after 72 hours. Methods: Human endothelial cells were allocated into Control, PGS, and PGS+Col groups. Scaffolds were characterized using FTIR and HNMR spectroscopy. Contact angel analysis and SEM were used to study wettability, surface morphology, and cell attachment. Cell survival was assessed using LDH leakage assay. Levels of Tie-1, Tie-2, VE-Cadherin, and VEGFR-2 were measured using western blotting and real-time PCR...
2022: Journal of Cardiovascular and Thoracic Research