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Journals Journal of Cardiovascular and ...

Journal of Cardiovascular and Thoracic Research

https://read.qxmd.com/read/38357568/effects-of-coenzyme-q10-supplementation-on-oxidative-stress-biomarkers-following-reperfusion-in-stemi-patients-undergoing-primary-percutaneous-coronary-intervention
#1
JOURNAL ARTICLE
Amirhossein Yazdi, Kimia Shirmohammadi, Erfan Parvaneh, Taher Entezari-Maleki, Seyed Kianoosh Hosseini, Akram Ranjbar, Maryam Mehrpooya
INTRODUCTION: It is well-established that oxidative stress is deeply involved in myocardial ischemia-reperfusion injury. Considering the potent antioxidant properties of coenzyme Q10 (CoQ10), we aimed to assess whether CoQ10 supplementation could exert beneficial effects on plasma levels of oxidative stress biomarkers in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPIC). METHODS: Seventy patients with the first attack of STEMI, eligible for PPCI were randomly assigned to receive either standard treatments plus CoQ10 (400 mg before PPCI and 200 mg twice daily for three days after PPCI) or standard treatments plus placebo...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357567/artificial-intelligence-in-cardiovascular-medicine-an-updated-review-of-the-literature
#2
REVIEW
Arian Zargarzadeh, Elnaz Javanshir, Alireza Ghaffari, Erfan Mosharkesh, Babak Anari
Screening and early detection of cardiovascular disease (CVD) are crucial for managing progress and preventing related morbidity. In recent years, several studies have reported the important role of Artificial intelligence (AI) technology and its integration into various medical sectors. AI applications are able to deal with the massive amounts of data (medical records, ultrasounds, medications, and experimental results) generated in medicine and identify novel details that would otherwise be forgotten in the mass of healthcare data sets...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357566/age-and-sex-related-differences-in-epidemiology-treatment-and-mortality-of-patients-with-st-segment-elevation-myocardial-infarction-in-iran
#3
JOURNAL ARTICLE
Mehdi Darabi, Reza Heidari Moghaddam, Farzaneh Godarzi, Sahar Karami, Soraya Siabani, Nahid Salehi
INTRODUCTION: Few studies have investigated the characteristics of patients with ST elevation myocardial infarction (STEMI) according to age and sex in Iran. This study aims to investigate the risk factors profile, treatment, and mortality of STEMI based on age and sex. METHODS: From 10th June 2016 to December 2019 a total of 2816, STEMI patients referred to the Imam Ali heart center of Kermanshah were included in the study. Profile of the risk factors, epidemiology, treatment and 30- day mortality for all cases in the age categories of 18-49, 50-64, and≥65 years were studied...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357565/association-between-nutritional-risk-status-and-health-related-quality-of-life-an-investigation-on-the-aging-patients-with-cardiovascular-disease
#4
JOURNAL ARTICLE
Leili Faraji Gavgani, Somayeh Alipour, Roghayeh Khabiri, Delara Laghousi, Parvin Sarbakhsh, Haniyeh Farajiazad, Mahdieh Abbasalizad Farhangi, Leila Jahangiry
INTRODUCTION: Acknowledging the considerable influence of undernutrition on health outcomes and HRQOL, this study sought to appraise the nutritional risk status of elderly patients with cardiovascular diseases (CVD) through the utilization of the Nutritional Risk Screening (NRS). Additionally, the investigation aimed to evaluate the correlation between NRS status and HRQOL within the context of patients referred to a cardiac hospital in Tabriz, Iran. METHODS: This cross-sectional study was conducted in Tabriz, Iran...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357564/prevalence-of-metabolic-syndrome-in-east-azerbaijan-iran-and-its-determinants-factors
#5
JOURNAL ARTICLE
Ali Farshbaf Khalili, Shahryar Razzaghi, Zeinab Nikniaz, Leila Nikniaz, Ali Hossein Zeinalzadeh
INTRODUCTION: Metabolic syndrome (MetS) is a prevalent metabolic disorder with increasing prevalence attributed to extended life expectancy. This study aims to investigate MetS prevalence and its determinants in the East-Azerbaijan population. METHODS: Conducted as a cross-sectional study within the East Azerbaijan region, this research is based on a major Lifestyle Promotion Project. The study encompasses 700 participants aged 15 to 65 years, representing the general population and selected using probability proportional to size multistage stratified cluster sampling...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357563/prevalence-and-characteristics-of-coronary-artery-anomalies-caas-in-3016-symptomatic-adult-participants-undergoing-coronary-computed-tomography-angiography-ccta-a-single-center-retrospective-study-in-iran
#6
JOURNAL ARTICLE
Abbas Andishmand, Hossein Montazerghaem, Ali Pedarzadeh, Hamid Reza Varastehravan, Hamidreza Mohammadi, Reza Nafisi Moghadam, Marzieh Azimizadeh, Mohammad Hossein Ahrar, Abdolrahim Khezri, Mohsen Andishmand
INTRODUCTION: Coronary artery anomalies (CAAs) are associated with an increased risk of cardiovascular events, including sudden cardiac death, especially in young people. A different prevalence has been reported based on the USED diagnostic modality. This study aimed to determine the prevalence and type of these anomalies using coronary computed tomography angiography (CCTA). METHODS: This single-center retrospective study was performed on 3016 consecutive cases who underwent CCTA for cardiac symptoms from March 2015 to August 2020 and the prevalence and types of CAAs were evaluated...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357562/assessment-of-ventricular-function-after-total-cavo-pulmonary-derivation-in-adult-patients-interest-of-global-longitudinal-strain
#7
Kaouther Hakim, Nouha Mekki, Rihab Benothmen, Mokbli Malek, Jarray Abdelkader, Msaad Hela, Habiba Mizouni, Ouarda Fatma
Ventricular dysfunction is the most frequent complication in adult patients post-Fontan completion. Through this work, we aim to evaluate ventricular systolic function by conventional echographic parameters and by global longitudinal strain (GLS) to determine the prediction of early ventricular systolic dysfunction. This is a prospective monocentric study enrolling 15 clinically stable adult Fontan patients with preserved ejection fraction (EF). Myocardial deformation study by GLS with speckle tracking technique in addition to a standard Doppler transthoracic echocardiography (TTE) was performed...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357561/evaluation-of-mmp-9-il-6-tnf-%C3%AE-levels-and-peripheral-blood-mononuclear-cells-genes-expression-of-mmp-9-and-timp-1-in-iranian-patients-with-coronary-artery-disease
#8
JOURNAL ARTICLE
Tooran Akbari, Toktam Kazemi Fard, Reza Fadaei, Rahim Rostami, Nariman Moradi, Monireh Movahedi, Soudabeh Fallah
INTRODUCTION: Coronary artery disease (CAD) is the main cause of death and is characterized by atherosclerosis in coronary arteries. Inflammation plays a crucial role in the progression and development of atherosclerosis. METHODS: The present study consisted of 132 Iranian individuals who underwent coronary angiography, 65 patients with CAD, and 67 controls. The matrix metalloproteinase-9 (MMP-9), TNF-α, IL-6, and vitamin D serum levels were measured by the ELISA technique...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357560/mechanical-properties-of-the-rabbit-and-human-decellularized-patches-for-well-tolerated-reinforced-organ-in-cardiac-tissue-engineering
#9
JOURNAL ARTICLE
Maryam Mousavi Khatat, Saeideh Same, Keyvan Moharamzadeh, Jafar Soleimani Rad, Ahmad Mehdipour, Leila Roshangar
INTRODUCTION: Natural decellularized patches have been developed as the therapeutic platform for the treatment of different diseases, especially cardiovascular disorders. Decellularized scaffolds (as both cell-seeded and cell-free patches) are broadly studied in heart tissue redevelopment in vivo and in vitro. The designed regenerative bio-scaffold must have desirable physicochemical properties including mechanical stiffness for load-bearing, and appropriate anatomical characteristics to mimic the native biological environment properly and facilitate tissue reconstruction...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357559/bariatric-arterial-embolization-in-patients-with-body-mass-index-ranging-from-25-to-40-kg-m-2-a-systematic-review-meta-analysis
#10
REVIEW
Rishabh Khurana, Niraj Nirmal Pandey, Sanjeev Kumar, Priya Jagia
The present review sought to evaluate by meta-analysis the efficacy of bariatric arterial embolization (BAE) in promoting weight loss in patients with body mass index (BMI) ranging from 25-40 kg/m2 . This study was performed and reported according to Preferred Reporting Items for Systematic reviews and Meta-analysis guidelines. A systematic literature search of MEDLINE, Embase Google Scholar, and World Health Organization Library database was done for studies evaluating BAE for promoting weight loss in patients with BMI ranging from 25-40 kg/ m2 published up to March 10, 2021...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38357558/reply-to-analysis-of-covariance-and-sample-size-calculation-for-comparing-means-in-randomized-controlled-trials
#11
JOURNAL ARTICLE
Naimeh Mesri Alamdari, Samad Ghaffari, Neda Roshanravan
No abstract text is available yet for this article.
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028723/polymorphism-of-rs599839-in-the-psrc1-gene-is-associated-with-coronary-artery-disease-in-an-iranian-population
#12
JOURNAL ARTICLE
Golnaz Houshmand, Mohammad Javad Alemzadeh-Ansari, Saeideh Mazloumzadeh, Niloofar Naderi, Maryam Pourirahim, Katayoun Heshmatzad, Majid Maleki, Samira Kalayinia
INTRODUCTION: Coronary artery disease (CAD) is the leading health complication worldwide because of its high prevalence and mortality. The association between CAD susceptibility and the rs599839 (C/T) polymorphism in the human proline and serine-rich coiled-coil ( PSRC1 ) was reported in a genome-wide association study. To validate this association, we performed this case-control study to genotype the 1p13.3 (rs599839) locus in a sample of the Iranian population with CAD (stenosis≥70% in≥1 coronary artery)...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028722/sevoflurane-mediated-modulation-of-oxidative-myocardial-injury
#13
JOURNAL ARTICLE
Siavash Sedghi, Wiam Z Khadra, Leili Pourafkari, Paul R Knight, Faraz A Alderson, Nader D Nader
INTRODUCTION: Volatile anesthetics offer protection when administered throughout an ischemic injury. We examined how volatile anesthetics modulate the cardiac myocytic injury associated with hydrogen peroxide. METHODS: Forty-eight Long-Evans rats were divided into four groups depending on the treatment: none (CONT), Glibenclamide (GLB); Sevoflurane (SEV); or GLB+SEV. Each group was further divided into two, one of which was exposed to hydrogen peroxide (H2 O2 )...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028721/the-hypoglycemic-effects-of-juglans-regia-l-internal-septum-in-type-2-diabetic-patients-a-double-blind-randomized-placebo-controlled-clinical-trial
#14
JOURNAL ARTICLE
Fatemeh Afra, Arman Zargaran, Nooshin Shirzad, Mahboobeh Hemmatabadi, Mahbube Ebrahimpur, Mehrdad Karimi, Mahnaz Khanavi, Mehrzad Mirshekari, Soha Namazi
INTRODUCTION: The internal septum of J.regia is traditionally used to control diabetes, and its effectiveness has been shown in animal studies. Accordingly, human clinical trials are needed to confirm its effectiveness on hemoglobin A1c (HbA1c), fasting blood sugar (FBS), blood insulin level, and insulin resistance as a complementary for better control of type 2 diabetes. METHODS: This study was a randomized, double-blinded, controlled trial. The lyophilized powder of extract of the internal septum of J...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028720/distinguishing-dual-from-duplicated-right-coronary-artery-revisiting-the-nomenclature
#15
Niraj Nirmal Pandey, Aprateem Mukherjee, Nitish Naik, Priya Jagia
We report a case of a 53-year-old man with a "short RCA" seen coursing within the proximal part of the right atrioventricular (AV) groove and terminating in the mid-portion of the right AV groove and a "long RCA" seen to have a proximal course outside the right AV groove, over the free wall of the right ventricle, where it gave rise to the right ventricular and acute marginal branches before returning to the right AV groove in its distal course. The discussion highlights the need for revisiting the nomenclature of "dual RCA and drawing a distinction between "dual" and "duplicated" RCA...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028719/atherosclerosis-preventive-effects-of-marrubiin-against-tnf-%C3%AE-induced-oxidative-stress-and-apoptosis
#16
JOURNAL ARTICLE
Ailar Nakhlband, Alireza Garjani, Nazli Saeedi, Yadollah Omidi, Samad Ghaffari, Jaleh Barar, Morteza Eskandani
INTRODUCTION: Atherosclerosis is a complicated cascade of inflammatory processes, oxidative stress, and apoptosis, making it the most prevalent cardiovascular disease. The onset and progression of cardiovascular diseases are greatly influenced by oxidative stress. Targeting oxidative stress is an effective strategy for treating such diseases. Marrubiin is a bioactive furan labdane diterpenoid acts as a strong antioxidant to protect against oxidative damage. This study aimed to investigate the protective effects of marrubiin against oxidative stress and apoptosis in a cellular model of the vascular system...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028718/plasminogen-activator-urokinase-receptor-as-a-diagnostic-and-prognostic-biomarker-in-type-2-diabetic-patients-with-cardiovascular-disease
#17
JOURNAL ARTICLE
Melak Saleh Mohammed, Hind Shakir Ahmed
INTRODUCTION: Cardiovascular diseases are the main cause of death among type 2 diabetic patients. Higher levels of plasminogen activator urokinase receptor have been found to predict morbidity and mortality across acute and chronic diseases in the common populace. This study aims to explore the role of serum plasminogen activator urokinase receptor levels as a cardiometabolic risk factor among type 2 diabetic Iraqi patients. METHODS: Seventy type 2 diabetic patients (40 male and 30 female) (mean age: 46...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028717/effectiveness-of-the-oral-clonidine-as-a-pre-anesthetic-medicine-for-thyroidectomy-surgery-a-randomized-clinical-trial
#18
JOURNAL ARTICLE
Sepideh Sadat Zahedi, Bahman Naghipour, Surur Zahedi, Sahar Zahedi, Seyed Ziaeddin Rasihashemi
INTRODUCTION: Hemodynamic disturbance is a common problem in patients undergoing thyroid surgery. It may be due to episodic increases in thyroid hormones (thyroid storm) or stimulation of the carotid sinus baroreflex. The aim of the present study was to investigate effectiveness of the pre-operative oral Clonidine on reducing these hemodynamic changes during total thyroidectomy surgery. METHODS: In a prospective, randomized, double-blind study, 80 patients scheduled for elective total thyroidectomy were randomized to receive either 0...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028716/association-of-nfkb1-gene-polymorphism-rs28362491-with-cardiometabolic-risk-factor-in-patients-undergoing-coronary-angiography
#19
JOURNAL ARTICLE
Zahra Darabi, Sara Jambarsang, Mohammad Yahya Vahidi Mehrjardi, Seyed Mostafa Seyed Hosseini, Mohammadtaghi Sarebanhassanabadi, Mahdieh Hosseinzadeh, Sara Beigrezaei, Azam Ahmadi Vasmehjani, Marzieh Taftian, Vahid Arabi, Maryam Motallaei, Faezeh Golvardi Yazdi, Amin Salehi-Abargouei, Azadeh Nadjarzadeh
INTRODUCTION: Genetic and environmental factors are involved in the pathogenesis of cardiovascular diseases (CVDs). The aim of the study was to investigate between the genotype of the NFKB1 gene and the cardiometabolic risk factor in patients undergoing coronary angiography. METHODS: This cross-sectional study was conducted on 462 adults (male and women) aged between 35 and 75 years who referred to Afshar Hospital for coronary angiography in 2021- 2022. The polymerase chain reaction restriction fragment length polymorphism method was used to detect the genotype of rs28362491...
2023: Journal of Cardiovascular and Thoracic Research
https://read.qxmd.com/read/38028715/anomalous-origin-of-the-left-coronary-artery-from-the-pulmonary-artery-a-midterm-experience-of-a-rare-entity-at-a-tertiary-care-center
#20
Rahul Bhushan, Manish Mallik, Ketika Potey, Vijay Grover, Palash Aiyer, Narender S Jhajhria
ALCAPA is a rare congenital heart disease. Presentation varies from asymptomatic to progressive heart failure and death. Surgical repair is indicated in all patients with a goal of restoring two coronary systems. Data was analysed in regard to presenting features, echocardiographic findings, various surgical approaches used and immediate, early and midterm post-operative results. Most common presentation was growth failure and seen in 6 patients. One patient was taken for elective PDA ligation and diagnosis of ALCAPA was made on table after PDA ligation as patient crashed subsequently...
2023: Journal of Cardiovascular and Thoracic Research
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