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Journal of Cardiovascular and Thoracic Research

Shailesh Kumar, Devyani Thakur, Ritesh Kumar Gupta, Alka Sharma
Amlodipine is a dihydropyridine calcium channel blocker which is widely used as an antihypertensive drug. Amlodipine overdose have been infrequently reported with occurrence of serious complications and even death in a few cases. We report an interesting case of a young lady who presented with refractory shock with acute kidney injury, which did not respond to therapy despite optimal fluid replacement and vasopressor support. The etiology of shock could not be ascertained and the patient was questioned again to elucidate the missing clue in the history...
2018: Journal of Cardiovascular and Thoracic Research
Muzaffer Kahyaoglu, Murat Velioglu, Cetin Gecmen, Arzu Kalayci, Ender Ozgun Cakmak, İbrahim Akin Izgi
Carotid artery stenting is a method used in the treatment of extracranial carotid artery stenosis that is becoming increasingly more common. Acute carotid thrombosis following CAS is a very rare and devastating complication that can be lethal for the patient unless treated immediately. We report a case of acute carotid stent thrombosis occurring immediately after emergent revascularization, and that was treated with intraarterial tissue plasminogen activator and intravenous tirofiban infusion.
2018: Journal of Cardiovascular and Thoracic Research
Mehrnoush Toufan Tabrizi, Roghaieh Rahimi Asl, Soheyla Nazarnia, Leili Pourafkari
Introduction: Morphology of bicuspid aortic valve (BAV) may have implication in the associated pathologies including aortic stenosis (AS), aortic insufficiency (AI) and aortic dilation. The aim of this study is to investigate the frequency and patterns of valvular dysfunction and aortopathy associated with different phenotypes of BAV in a referral center in northwest of Iran. Methods: In this prospective study patients who presented to our echocardiography lab between January 2014 and December 2015 and were diagnosed with BAV were assessed...
2018: Journal of Cardiovascular and Thoracic Research
Farahnaz Nikdoust, Elham Bolouri, Seyed Abdolhussein Tabatabaei, Mahdi Goudarzvand, Seyedeh Tahereh Faezi
Introduction: Systemic lupus erythematosus (SLE) myocarditis occurs in between 5% and 10% of patients with lupus. Global longitudinal strain (GLS) via speckle tracking echocardiography can detect cardiac involvement in patients suffering from SLE. We decided to determine the echocardiographic features and subsequent early diagnosis of cardiac involvement in patients with SLE utilizing the GLS index via speckle tracking echocardiography. Methods: In this cross-sectional study, we compared female patients with SLE of at least 2 years' duration and healthy controls in terms of the left ventricular (LV) GLS via speckle tracking echocardiography...
2018: Journal of Cardiovascular and Thoracic Research
Gholamhossein Alishiri, Maryam Moshkani Farahani, Ali Sadr, Mahmood Salesi, Mostafa Rahemi, Bahador Rezapoor
Introduction: Coronary Artery Disease (CAD) is known as the major cause of morbidity and mortality in the world with a growing trend, especially in some developing countries. CAD commonly observed in elderly cases, however; recently it is usually found in young adults. In this study, we aimed to evaluate the prevalence of anti-phospholipid antibody syndrome (APS) in patients with premature CAD. Methods: The cross-sectional study was conducted in Baqiyatallah hospital from April 2012 to April 2016. Patients with premature CAD were included in the study...
2018: Journal of Cardiovascular and Thoracic Research
Hashem Jarineshin, Maryam Sharifi, Saeid Kashani
Introduction: The present guidelines recommend placing the catheter tip in the superior vena cava (SVC) above the pericardial cephalic reflection. The aim of this study was to compare the accuracy of two different approaches in locating the tip of the Central venous catheter (CVC) at the suggested vascular zone. Methods: This was an interventional study on two hundred patients undergoing Coronary artery bypass surgery (CABG) operation who required a central venous cannulation. They were randomly assigned into two groups...
2018: Journal of Cardiovascular and Thoracic Research
Ramin Heshmat, Zeinab Hemati, Mostafa Qorbani, Laleh Nabizadeh Asl, Mohammad Esmaeil Motlagh, Hasan Ziaodini, Majzoubeh Taheri, Zeinab Ahadi, Gita Shafiee, Tahereh Aminaei, Hooman Hatami, Roya Kelishadi
Introduction: Metabolic syndrome (MetS) is one of the common metabolic disorders seen in children and adolescents. This study aims to assess the rate of the MetS and its associated factors in a nationally-representative sample of Iranian pediatric age groups. Methods: This nationwide cross- sectional study was designed in 2015 in 30 provinces of Iran. Participants consisted of 4,200 school students, aged 7-18 years, studied in a national school-based surveillance program (CASPIAN-V). Physical examination and laboratory tests were performed using standard protocols...
2018: Journal of Cardiovascular and Thoracic Research
Mohsen Khosravani-Rudpishi, Adel Joharimoghadam, Elham Rayzan
Introduction: Although coronary tortuosity is relatively common in coronary angiograms, there is much debate over the significance of this anatomical variation. So in this study the relation between significant coronary tortuosity (SCT) and coronary artery disease (CAD) was examined. Methods: The cross-sectional study included 737 patients (57% male) who were admitted to the hospital for a coronary angiography, based on their symptoms or non-invasive imaging. Coronary arteries defined as SCT are in the presence of either ≥3 consecutive curvatures of 90◦ to 180◦ or ≥2 consecutive curvatures of ≥180◦ measured at the end-diastole, in a major epicardial coronary artery ≥2 mm in diameter...
2018: Journal of Cardiovascular and Thoracic Research
Samira Nozari, Nazila Fathi Maroufi, Mohammad Nouri, Mirhamid Paytakhti Oskouei, Javad Shiralizade, Farshid Yekani, Mina Mamipour, Yousef Faridvand
Introduction: Lipid metabolism disorder or hyperlipidemia is known as a risk factor for cardiovascular disease, the increase in serum homocysteine and leptin are associated with atherosclerotic disease. The purpose of the present study was to examine the effects of bovine lactoferrin (bLF) on serum homocysteine (Hcy), apolipoproteinA-I (ApoA-I) and B (ApoB), leptin and lipid profile changes in high-cholesterol-diet (HCD) fed rats. Methods: The Healthy Adult Sprague-Dawley (SD) male rats were randomly assigned into three experimental groups...
2018: Journal of Cardiovascular and Thoracic Research
Tatiana N Enina, Vadim A Kuznetsov, Anna M Soldatova, Tatiana I Petelina, Dmitriy V Krinochkin, Alexander Yu Rychkov, Olga Yu Nochrina
Introduction: Gender differences in cardiac resynchronisation therapy (CRT) response are not clear enough. This study aimed to assess gender influence on systemic inflammation, neurohormonal activation, fibrosis in patients with congestive heart failure (CHF) and CRT. Methods: We compared group I (61 men) and group II (16 women) of patients undergoing CRT. Plasma levels of Nt-proBNP, interleukin (IL)-1β, IL-6, IL-10, tumor necrosis factor alpha (TNF-α), C-reactive protein, galectin-3 (Gal-3), metalloproteinase-9 (MMP-9), tissue inhibitors of metalloproteinase 1 and 4 (TIMP-1, TIMP-4), ratio MMP-9/TIMP-1, MMP-9/TIMP-4 were measured...
2018: Journal of Cardiovascular and Thoracic Research
Masoud Tarbiat, Maryam Davoudi, Sayed Ahmadreza Salimbahrami
Introduction: Percutaneous subclavian vein catheterization via infraclavicular approach is one of the most widely used cannulation techniques for inserting catheters into a central vein. The aim of this study was to evaluate influence of arm position during infraclavicular subclavian vein catheterization with landmark-based technique in coronary artery bypass graft (CABG) surgery. Methods: Between September 2017 and June 2018, this prospective randomized clinical trial was performed in 320 patients. The patients were randomly assigned to the Neutral group (the arms kept by the side) or Abduction group (the arm was abducted to 90°)...
2018: Journal of Cardiovascular and Thoracic Research
Mustafa Akbulut, Ozgur Arslan, Adnan Ak, Serpil Tas, Davut Cekmecelioglu, Mesut Sismanoglu, Altug Tuncer
Introduction: Our experience in minimally invasive procedures and improvement of graft technology enables easy and successful operation carried out even with complex thoracic aortic diseases from limited surgical area. However, it should be more than one incision or cannulation site for such intervention. We aimed to present our experience and results of 23 patients who has ascending aorta and aortic arch pathologies of which we operated with J-shaped partial sternotomy and innominate vein cannulation. Methods: From January 2014 to January 2016, 23 patients with aorta and aortic valve pathologies who underwent aortic surgery with J-shaped partial sternotomy and innominate vein cannulation included...
2018: Journal of Cardiovascular and Thoracic Research
Salik Nazir, Saroj Lohani, Niranjan Tachamo, Muhammad Sohail Khan, Bidhya Timilsina, Faraz Khan Luni, Anthony Donato
Introduction: Transcatheter mitral valve-in-valve (ViV) & valve-in-ring (ViR) are relatively novel therapeutic alternatives for patients with degenerated bioprostheses or failed annuloplasty rings whose reoperative risk is too high. The predominant procedural access for both procedures is transapical or transseptal. However, whether there are differences in outcomes of this procedure using transseptal versus transapical access has not yet been defined. Methods: We conducted a systematic review of all published articles from MEDLINE and EMBASE to explore the outcomes of these two procedural approaches...
2018: Journal of Cardiovascular and Thoracic Research
Efrén Martínez-Quintana, Fayna Rodríguez-González
No abstract text is available yet for this article.
2018: Journal of Cardiovascular and Thoracic Research
Amir Ghaffarzad, Reza Javadrashid, Elyar Sadeghi-Hokmabadi, Reza Jamal Arvanaghi, Hassan Soleimanpour, Samad Ej Golzari
Vertebral artery occlusion (VAO) may result from closed head or neck trauma and can be lifethreatening due to brain-stem and cerebellar infarction. CT angiography is recommended as a screening diagnostic tool in selected patients after blunt cervical trauma. A 24-year-old woman was admitted to our emergency department with left hemiplegia two days after motor vehicle collision. Final diagnosis of occlusion of the right vertebral artery was made in CT angiography. She was treated with anticoagulant for 4 days then discharged with 5/5 muscle forces...
2018: Journal of Cardiovascular and Thoracic Research
Alireza Jahangirifard, Zargham Hossein Ahmadi, Abolghasem Daneshvar Kakhaki, Behrooz Farzanegan, Kambiz Sheikhy
Some advanced thoracic malignancy cannot be resected safely by using of conventional ventilation, so some sort of cardiopulmonary support is needed for hemodynamic and ventilation management of the patient. Using extracorporeal membrane oxygenation (ECMO) in comparing with cardiopulmonary bypass has some advantages. Three patients with huge thoracic tumors with different ages experienced major surgery in our center by using ECMO in order to face major complications mainly due to the size of mass to achieve better hemostatic stabilities, lower bleeding, and injuries to main airways and secure oxygenation...
2018: Journal of Cardiovascular and Thoracic Research
Mehrnoush Toufan, Sakineh Hadi, Afshin Habibzadeh
Introduction: Ischemic mitral regurgitation (IMR) is common after acute myocardial infarction (AMI) which is associated with long-term cardiovascular mortality. Size, transmurality and location of the myocardial infarction (MI) has role on the development of IMR. In this study we evaluated the severity of IMR after different types of MI. Methods: One-hundred patients with the first AMI were recruited and according to echocardiographic findings were categorized to have moderate to severe IMR (case group, n=50) or trivial or no IMR (control group, n=50)...
2018: Journal of Cardiovascular and Thoracic Research
Behrouz Baghaiee, Pouran Karimi, Khadije Ebrahimi, Saeed Dabagh Nikoo Kheslat, Mohammad Hossein Sadeghi Zali, Amir Mohammad Daneshian Moghaddam, Mohammad Sadaghian
Introduction: This study was aimed at determining the effects of a 12-week aerobic exercise program on markers of hypertension in men. Methods: The study was of a semi-experimental design featuring repeated measurements. A total of 40 men (age range=37.9 ± 2.68) with primary hypertension were divided into two groups, namely, the exercise group (n=20) and the control group (n=20) (systolic blood pressure [SBP]: 140.531 ± 0.23, diastolic blood pressure [DBP]: 90.71 ± 0.05). The exercise group participated in a 12-week aerobic exercise program (55% to 70% of HRmax)...
2018: Journal of Cardiovascular and Thoracic Research
Elnaz Daneshzad, Shaghayegh Emami, Manije Darooghegi Mofrad, Sahar Saraf-Bank, Pamela J Surkan, Leila Azadbakht
Introduction: Cardiovascular disease (CVD) is one of the most important causes of mortality. Healthy diets can decrease CVDs and other chronic diseases especially in patients with type 2 diabetes. In this study, we investigate association between adherence to the modified Nordic diet and cardiovascular risk factors among patients with type 2 diabetes. Methods: This cross-sectional study was conducted among 339 type 2 diabetic patients. Anthropometric indices, blood pressure, and biochemical tests were evaluated...
2018: Journal of Cardiovascular and Thoracic Research
Ata Firouzi, Ali Kazem Moussavi, Ahmad Mohebbi, Mohammad Javad Alemzadeh-Ansari, Reza Kiani, Hamid Reza Sanati, Bahram Mohebbi, Farshad Shakerian, Ali Zahedmehr, Mohammad Mostafa Ansari-Ramandi, Saeed Oni Heris, Bahar Ghaleshi, Fatemeh Ghorbani
Introduction: There is some controversy over the efficacy of statins for the prevention of contrastinduced nephropathy (CIN). There have also been reports on varying efficacies of different statins. Hence, in this study the efficacy of atorvastatin and rosuvastatin for the prevention of CIN was assessed. Methods: This single-blind randomized clinical trial was performed on 495 random patients with myocardial infarction with ST-segment elevation undergoing primary percutaneous coronary intervention (PCI) in a training referral hospital in 2015...
2018: Journal of Cardiovascular and Thoracic Research
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