Okan Avci, Eyyup Çavdar, Yakup İriağaç, Kubilay Karaboyun, Aliye Çelikkol, Tuğba İlkem Kurtoğlu Özçağlayan, Meltem Öznur, Sibel Özkan Gürdal, Erdoğan Selçuk Şeber
Aim of the study: Although early diagnosis of breast cancer (BC) is often associated with a good prognosis, there is currently no biomarker with high sensitivity serving this purpose. B7H3, a recently identified member of the B7 family, appears to inhibit antitumor immunity. We investigated the soluble B7H3 (sB7H3) level in BC and its relationship with clinicopathological variables and stromal tumor-infiltrating lymphocytes (sTILs). Material and methods: The study, which was designed as a cross-sectional trial between January 2020 and September 2021, included 93 BC patients, 20 patients with benign breast disease (BBD) and 14 healthy volunteers as the control group...
2022: Contemporary Oncology Współczesna Onkologia