Óscar Fernández Fernández, Lucienne Costa-Frossard, Maria Luisa Martínez Ginés, Paloma Montero Escribano, José María Prieto González, Lluís Ramió-Torrentà, Yolanda Aladro, Ana Alonso Torres, Elena Álvarez Rodríguez, Andrés Labiano-Fontcuberta, Lamberto Landete Pascual, Ambrosio Miralles Martínez, Ester Moral Torres, Pedro Oliva-Nacarino
INTRODUCTION: The Spasticity-Plus Syndrome (SPS) in multiple sclerosis (MS) refers to a combination of spasticity and other signs/symptoms such as spasms, cramps, bladder dysfunction, tremor, sleep disorder, pain, and fatigue. The main purpose is to develop a user-friendly tool that could help neurologists to detect SPS in MS patients as soon as possible. METHODS: A survey research based on a conjoint analysis approach was used. An orthogonal factorial design was employed to form 12 patient profiles combining, at random, the eight principal SPS signs/symptoms...
2024: Frontiers in Neurology