journal
https://read.qxmd.com/read/37731859/predictive-value-of-the-oxford-acute-severity-of-illness-score-in-acute-stroke-patients-with-stroke-associated-pneumonia
#1
JOURNAL ARTICLE
Ximei Wang, Jianhua Xia, Yanhua Shan, Yang Yang, Yun Li, Haiyan Sun
BACKGROUND: Stroke-associated pneumonia (SAP) is associated with a poor prognosis and a high mortality rate in stroke patients. However, the accuracy of early prediction of SAP is insufficient, and there is a lack of effective prognostic evaluation methods. Therefore, in this study, we investigated the predictive value of the Oxford Acute Severity of Illness Score (OASIS) in SAP to provide a potential reference index for the incidence and prognosis of SAP. METHODS: We recruited a total of 280 patients with acute ischemic stroke who had been diagnosed and treated in the Zhumadian Central Hospital between January 2021 and January 2023...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731858/calming-effect-of-clinically-designed-improvisatory-music-for-patients-admitted-to-the-epilepsy-monitoring-unit-during-the-covid-19-pandemic-a-pilot-study
#2
JOURNAL ARTICLE
Borna Bonakdarpour, Guangyu Zhou, Daniel Huang, Catherine T Vidano, Stephan Schuele, Christina Zelano, Clara Takarabe
BACKGROUND: Epilepsy monitoring requires simulating seizure-inducing conditions which frequently causes discomfort to epilepsy monitoring unit (EMU) patients. COVID-19 hospital restrictions added another layer of stress during hospital admissions. The purpose of this pilot study was to provide evidence that live virtual Clinically Designed Improvisatory Music (CDIM) brings relief to EMU patients for their psychological distress. METHODS: Five persons with epilepsy (PWEs) in the EMU during the COVID-19 lockdown participated in the study (average age ± SD = 30...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731857/reversible-splenial-lesion-syndrome-in-children-a-retrospective-study-of-130-cases
#3
JOURNAL ARTICLE
Hui Chen, Xiongying Yu, Yong Chen, Huaping Wu, Zhuqiang Wu, Jianmin Zhong, Zhenyu Tang
BACKGROUND: Reversible splenial lesion syndrome (RESLES) is a new clinico-radiological syndrome. We retrospectively analyzed the clinical features of 130 children with RESLES in China, which is the largest case series available in the literature. METHODS: The clinical data of children diagnosed as RESLES in Jiangxi Provincial Children's Hospital between 2017 and 2023 were retrospectively analyzed. The 130 cases were divided into two groups: ≤ 3 years old group (group A) ( n = 83) and > 3 years old group (group B) ( n = 47)...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731856/biomarkers-associated-with-functional-improvement-after-stroke-rehabilitation-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
REVIEW
Gengbin Chen, Manfeng Wu, Jialin Chen, Cailing Zhang, Quan Liu, Yinchun Zhao, Guangqing Xu, Yue Lan
OBJECTIVE: This study aims to identify blood and cerebrospinal fluid biomarkers that are correlated to the functional improvement of stroke patients after rehabilitation therapy, and provide ideas for the treatment and evaluation of stroke patients. METHODS: The PubMed, Web of Science, and Embase databases were searched for articles published in the English language, from inception to December 8, 2022. RESULTS: A total of 9,810 independent records generated 50 high-quality randomized controlled trials on 119 biomarkers...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731855/case-report-usefulness-of-angioscopy-in-determining-antiplatelet-drug-reduction-after-carotid-artery-stenting
#5
Kenji Fukutome, Mikio Shiba, Shuta Aketa, Takaaki Mitsui, Yuki Shiraishi, Hiromichi Hayami, Yasutaka Murakami, Ryuta Matsuoka, Rinsei Tei, Yasushi Shin, Yasushi Motoyama
We report a case in which neointima was confirmed by angioscopy and antiplatelet drug administration was reduced 2 months after carotid artery stenting (CAS). A patient in their 80s was scheduled to undergo resection for renal cancer; however, he also had right cervical internal carotid artery stenosis. Because this was a risk for general anesthesia, CAS was performed after first starting dual antiplatelet therapy. Urologically, early reduction of antiplatelet drugs was necessary for a nephrectomy. Although no obvious neointima could be identified on ultrasound 2 months after CAS, thin neointima was observed using angioscopy...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731854/associations-between-perioperative-sleep-patterns-and-clinical-outcomes-in-patients-with-intracranial-tumors-a-correlation-study
#6
JOURNAL ARTICLE
Yang Liu, Fan Wu, Xiaoyu Zhang, Mengyang Jiang, Yiqiang Zhang, Chenhui Wang, Yongxing Sun, Baoguo Wang
OBJECTIVE: Although the quality of perioperative sleep is gaining increasing attention in clinical recovery, its impact role remains unknown and may deserve further exploration. This study aimed to investigate the associations between perioperative sleep patterns and clinical outcomes among patients with intracranial tumors. METHODS: A correlation study was conducted in patients with intracranial tumors. Perioperative sleep patterns were assessed using a dedicated sleep monitor for 6 consecutive days...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731853/rethinking-the-reliability-and-accuracy-of-biomarkers-in-cns-originating-evs-for-parkinson-s-disease-and-multiple-system-atrophy
#7
JOURNAL ARTICLE
Hash Brown Taha
No abstract text is available yet for this article.
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731852/surface-based-correlates-of-cognition-along-the-alzheimer-s-continuum-in-a-memory-clinic-population
#8
JOURNAL ARTICLE
Michelle M Coleman, Cierra M Keith, Kirk Wilhelmsen, Rashi I Mehta, Camila Vieira Ligo Teixeira, Mark Miller, Melanie Ward, Ramiro Osvaldo Navia, William T McCuddy, Pierre-François D'Haese, Marc W Haut
Composite cognitive measures in large-scale studies with biomarker data for amyloid and tau have been widely used to characterize Alzheimer's disease (AD). However, little is known about how the findings from these studies translate to memory clinic populations without biomarker data, using single measures of cognition. Additionally, most studies have utilized voxel-based morphometry or limited surface-based morphometry such as cortical thickness, to measure the neurodegeneration associated with cognitive deficits...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731851/editorial-moyamoya-disease-natural-history-and-therapeutic-challenges
#9
EDITORIAL
Teodor Svedung Wettervik, Markus Fahlström, Johan Wikström, Per Enblad, Anders Lewén
No abstract text is available yet for this article.
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731850/a-systematic-review-and-meta-analysis-of-health-utility-values-among-patients-with-ischemic-stroke
#10
Jiting Zhou, Qiran Wei, Hongfei Hu, Wei Liu, Xin Guan, Aixia Ma, Luying Wang
PURPOSE: Ischemic stroke (IS) has a considerable impact on the health-related quality of life (HRQoL) of patients. A systematic review was conducted to summarize and synthesize the HRQoL reported from IS patients. METHODS: An electronic search was performed in PubMed, Web of Science, ScienceDirect, Embase, and Cochrane Library databases from inception to February 2022 for studies measuring utility values in IS patients. Basic information about the studies, patient characteristics, measurement of the utility values, and utility values were extracted and summarized...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731849/assessing-white-matter-microstructural-changes-in-idiopathic-normal-pressure-hydrocephalus-using-voxel-based-r2-relaxometry-analysis
#11
JOURNAL ARTICLE
Yuya Kano, Yuto Uchida, Hirohito Kan, Keita Sakurai, Susumu Kobayashi, Kento Seko, Keisuke Mizutani, Toshihiko Usami, Koji Takada, Noriyuki Matsukawa
BACKGROUND: R2* relaxometry and quantitative susceptibility mapping can be combined to distinguish between microstructural changes and iron deposition in white matter. Here, we aimed to explore microstructural changes in the white matter associated with clinical presentations such as cognitive impairment in patients with idiopathic normal-pressure hydrocephalus (iNPH) using R2* relaxometry analysis in combination with quantitative susceptibility mapping. METHODS: We evaluated 16 patients clinically diagnosed with possible or probable iNPH and 18 matched healthy controls (HC) who were chosen based on similarity in age and sex...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37731848/access-to-mechanical-thrombectomy-and-ischemic-stroke-mortality-in-japan-a-spatial-ecological-study
#12
JOURNAL ARTICLE
Kazuki Ohashi, Toshiya Osanai, Kensuke Fujiwara, Takumi Tanikawa, Yuji Tani, Soichiro Takamiya, Hirotaka Sato, Yasuhiro Morii, Katsuhiko Ogasawara
BACKGROUND: Advances in stroke treatment have greatly improved outcomes; however, disparities in access to treatment might increase. Achieving equitable access to stroke treatment is a health policy challenge, as rapid treatment is essential for positive outcomes. This ecological cross-sectional study aimed to determine the relationship between the disparities in spatial accessibility to mechanical thrombectomy (SAMT) and stroke mortality rates in Japan, hypothesizing that disparities in SAMT may increase the differences in stroke mortality between regions...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37727579/evaluation-of-intracranial-stenting-in-a-simulated-training-and-assessment-environment-for-neuroendovascular-procedures
#13
JOURNAL ARTICLE
Anna A Kyselyova, Andreas M Frölich, Maxim Bester, Caspar Brekenfeld, Jan-Hendrik Buhk, Andreas Ding, Frank Nagl, Tobias J Jost, Helena Guerreiro, Ngoc Tuan Ngo, Jens Fiehler, Fabian Flottmann
PURPOSE: Given the inherent complexity of neurointerventional procedures and the associated risks of ionizing radiation exposure, it is crucial to prioritize ongoing training and improve safety protocols. The aim of this study is to assess a training and evaluation in-vitro environment using a vascular model of M1 stenosis, within a clinical angiography suite, without relying on animal models or X-ray radiation. MATERIALS AND METHODS: Using a transparent model replicating M1 stenosis, we conducted intracranial stenting procedures with four different setups (Gateway & Wingspan, Gateway & Enterprise, Neurospeed & Acclino, and Pharos Vitesse)...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719767/editorial-anesthetic-neurotoxicity-in-developing-brains-mechanisms-biomarkers-and-therapeutic-targets
#14
EDITORIAL
Yang Yu, Yonghao Yu, Yiying Zhang, Huihui Miao
No abstract text is available yet for this article.
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719766/initiation-of-combined-antiretroviral-therapy-confers-suboptimal-beneficial-effects-on-neurovascular-function-in-people-with-hiv
#15
JOURNAL ARTICLE
Meera V Singh, Md Nasir Uddin, Vir B Singh, Angelique N Peterson, Kyle D Murray, Yuchuan Zhuang, Alicia Tyrell, Lu Wang, Madalina E Tivarus, Jianhui Zhong, Xing Qiu, Giovanni Schifitto
INTRODUCTION: Due to advances in combined anti-retroviral treatment (cART), there is an increased burden of age-related cerebrovascular disease (CBVD), in people living with HIV (PWH). The underlying CNS injury can be assessed by measuring cerebral blood flow (CBF) and cerebrovascular reactivity (CVR). METHODS: 35 treatment-naïve PWH and 53 HIV negative controls (HC) were enrolled in this study. Study participants underwent T1-weighted anatomical, pseudo-continuous arterial spin labeling, and resting-state functional MRI to obtain measures of CBF and CVR prior to starting cART treatment and at two-time points (12 weeks and 2 years) post-cART initiation...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719765/toward-the-use-of-novel-alternative-methods-in-epilepsy-modeling-and-drug-discovery
#16
REVIEW
Claudia Miguel Sanz, Miriam Martinez Navarro, Daniel Caballero Diaz, Gentzane Sanchez-Elexpuru, Vincenzo Di Donato
Epilepsy is a chronic brain disease and, considering the amount of people affected of all ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure medications (ASMs) have been released since 1993, yet despite substantial advancements in our understanding of the molecular mechanisms behind epileptogenesis, over one-third of patients continue to be resistant to available therapies. This is partially explained by the fact that the majority of existing medicines only address seizure suppression rather than underlying processes...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719764/secondary-neurodegeneration-following-stroke-what-can-blood-biomarkers-tell-us
#17
REVIEW
Stefano Brunelli, Emilia Giannella, Mirko Bizzaglia, Domenico De Angelis, Giulia Maria Sancesario
Stroke is one of the leading causes of death and the primary source of disability in adults, resulting in neuronal necrosis of ischemic areas, and in possible secondary degeneration of regions surrounding or distant to the initial damaged area. Secondary neurodegeneration (SNDG) following stroke has been shown to have different pathogenetic origins including inflammation, neurovascular response and cytotoxicity, but can be associated also to regenerative processes. Aside from focal neuronal loss, ipsilateral and contralateral effects distal to the lesion site, disruptions of global functional connectivity and a transcallosal diaschisis have been reported in the chronic stages after stroke...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719763/development-and-validation-of-a-deep-learning-based-automatic-segmentation-model-for-assessing-intracranial-volume-comparison-with-neuroquant-freesurfer-and-synthseg
#18
JOURNAL ARTICLE
Pae Sun Suh, Wooseok Jung, Chong Hyun Suh, Jinyoung Kim, Jio Oh, Hwon Heo, Woo Hyun Shim, Jae-Sung Lim, Jae-Hong Lee, Ho Sung Kim, Sang Joon Kim
BACKGROUND AND PURPOSE: To develop and validate a deep learning-based automatic segmentation model for assessing intracranial volume (ICV) and to compare the accuracy determined by NeuroQuant (NQ), FreeSurfer (FS), and SynthSeg. MATERIALS AND METHODS: This retrospective study included 60 subjects [30 Alzheimer's disease (AD), 21 mild cognitive impairment (MCI), 9 cognitively normal (CN)] from a single tertiary hospital for the training and validation group (50:10)...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719762/visualization-and-clinical-relevance-of-the-endolymphatic-duct-and-sac-in-m%C3%A3-ni%C3%A3-re-s-disease
#19
JOURNAL ARTICLE
Lisa M H de Pont, Maartje T P M Houben, Thijs O Verhagen, Berit M Verbist, Mark A van Buchem, Claire C Bommeljé, Henk M Blom, Sebastiaan Hammer
BACKGROUND: Ménière's disease (MD) is a chronic inner ear disorder with a multifactorial etiology. Decreased visualization of the endolymphatic duct (ED) and sac (ES) is thought to be associated with MD, although controversy exists about whether this finding is specific to MD. Recent literature has revealed that two distinct ES pathologies, developmental hypoplasia and epithelial degeneration, can be distinguished in MD using the angular trajectory of the vestibular aqueduct (ATVA) or ED-ES system as a radiographic surrogate marker...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37719761/addressing-the-elephant-in-the-room-understanding-functional-neurological-symptom-disorder-through-the-lens-of-culture-and-religion
#20
JOURNAL ARTICLE
Iram Zehra Bokharey, Urusa Fahim, Khola Tahir, Zarish Shireen
Owing to the dearth of scholarly works to understand the presence of Functional Neurological Symptom Disorder (FNSD) among mental health patients in Pakistan, this study sought to understand how cultural and religious conflicts are implicated in the aetiology of FNSD. The study recruited 22 participants, comprising five men and 17 women. The participants were recruited from the Department of Psychiatry at Services Hospital, Lahore, Pakistan. Semi-structured interviews were conducted and analyzed through Thematic Analysis...
2023: Frontiers in Neurology
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