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JOURNAL ARTICLE
Adam Whitley, Petr Kocián, Andrej Nikov, Denisa Krejčí, Lucie Pehalová, Milan Blaha, Ladislav Dušek, Robert Gürlich
BACKGROUND: The aim of this study was to compare trends in mortality and incidence, clinicopathological features and survival of patients diagnosed with pancreatic ductal adenocarcinoma under 50 years of age (early-onset pancreatic cancer [EOPC]) with patients diagnosed over 50 years of age (late-onset pancreatic cancer [LOPC]). METHODS: The national oncological registry of the Czech Republic was reviewed to identify all patients with histologically confirmed pancreatic ductal adenocarcinoma diagnosed between the years 1985 and 2015...
September 26, 2023: Journal of Hepato-biliary-pancreatic Sciences
#2
JOURNAL ARTICLE
Fumihiro Terasaki, Shinya Hirakawa, Hisateru Tachimori, Teiichi Sugiura, Atsushi Nanashima, Shohei Komatsu, Hiroaki Miyata, Yoshihiro Kakeji, Yuko Kitagawa, Masafumi Nakamura, Itaru Endo
BACKGROUND: The aim of this study was to analyze the nationwide surgical outcome of a left trisectionectomy (LT) and to identify the perioperative risk factors associated with its morbidity. METHODS: Cases of LT for hepato-biliary malignancies registered at the Japanese National Clinical Database between 2013 and 2019 were retrospectively reviewed. Statistical analyses were performed to identify the perioperative risk factors associated with a morbidity of Clavien-Dindo classification (CD) ≥III...
September 26, 2023: Journal of Hepato-biliary-pancreatic Sciences
#3
JOURNAL ARTICLE
Mina Fukasawa, Toru Watanabe, Haruyoshi Tanaka, Ayaka Itoh, Nana Kimura, Kazuto Shibuya, Isaku Yoshioka, Kenta Murotani, Kenichi Hirabayashi, Tsutomu Fujii
BACKGROUND: The frequency and prognosis of positive peritoneal washing cytology (CY1) in resectable pancreatic ductal adenocarcinoma (R-PDAC) remains unclear. The objective of this study was to identify the clinical implications of CY1 in R-PDAC and staging laparoscopy (SL). METHODS: We retrospectively analyzed 115 consecutive patients with R-PDAC who underwent SL between 2018 and 2022. Patients with negative cytology (CY0) received radical surgery after neoadjuvant chemotherapy, while CY1 patients received systemic chemotherapy and were continuously evaluated for cytology...
September 26, 2023: Journal of Hepato-biliary-pancreatic Sciences
#4
JOURNAL ARTICLE
Yusuke Kazami, Junichi Kaneko, Deepak Keshwani, Yoshiro Kitamura, Ryugen Takahashi, Yuichiro Mihara, Akihiko Ichida, Yoshikuni Kawaguchi, Nobuhisa Akamatsu, Kiyoshi Hasegawa
BACKGROUND: Anatomic virtual hepatectomy with precise liver segmentation for hemilivers, sectors, or Couinaud's segments using conventional three-dimensional simulation is not automated and artificial intelligence (AI)-based algorithms have not yet been applied. METHODS: Computed tomography data of 174 living-donor candidates for liver transplantation (training data) were used for developing a new two-step AI algorithm to automate liver segmentation that was validated in another 51 donors (validation data)...
September 25, 2023: Journal of Hepato-biliary-pancreatic Sciences
#5
JOURNAL ARTICLE
Teiichi Sugiura, Hirochika Toyama, Akira Fukutomi, Hirofumi Asakura, Yuriko Takeda, Kouji Yamamoto, Satoshi Hirano, Sohei Satoi, Ippei Matsumoto, Shinichiro Takahashi, Soichiro Morinaga, Makoto Yoshida, Yasunaru Sakuma, Hidetaka Iwamoto, Yasuhiro Shimizu, Katsuhiko Uesaka
OBJECTIVE: The aim of the present study was to investigate which treatment, neoadjuvant chemoradiotherapy (NAC-RT) with S-1 or combination neoadjuvant chemotherapy with gemcitabine and S-1 (NAC-GS), is more promising as neoadjuvant treatment (NAT) for resectable pancreatic cancer in terms of effectiveness and safety. METHODS: In the NAC-RT with S-1 group, the patients received a total radiation dose of 50.4 Gy in 28 fractions with oral S-1. In the NAC-GS group, the patients received intravenous gemcitabine at a dose of 1000 mg/m2 with oral S-1 for two cycles...
September 25, 2023: Journal of Hepato-biliary-pancreatic Sciences
#6
Riki Ninomiya, Masahiko Komagome, Satoru Abe, Takehiro Chiyoda, Ryota Kogure, Akifumi Kimura, Akira Maki, Yoshifumi Beck
No abstract text is available yet for this article.
September 24, 2023: Journal of Hepato-biliary-pancreatic Sciences
#7
JOURNAL ARTICLE
Abdimajid Mohamed, Laura Nicolais, Timothy L Fitzgerald
BACKGROUND: Textbook outcome (TO) is a valuable metric to assess postoperative outcomes. The aim of this study was to assess TO in patients undergoing hepatopancreatic surgery. METHODS: This was a retrospective cohort NSQIP study from 2015 to 2018. TOs are defined as no complication or mortality and length of stay within the 75th percentile. RESULTS: This study included 44 235 patients. Of those patients, 61% underwent pancreatic surgery (PS) and 39% hepatic surgery (HS)...
September 21, 2023: Journal of Hepato-biliary-pancreatic Sciences
#8
JOURNAL ARTICLE
Tatsuya Ishii, Tsuyoshi Hayashi, Hajime Yamazaki, Risa Nakamura, Kosuke Iwano, Ryo Ando, Haruka Toyonaga, Toshifumi Kin, Kuniyuki Takahashi, Akio Katanuma
BACKGROUND: Cholecystitis is a major adverse event after self-expandable metallic stent placement for distal biliary obstruction (DBO). Covered self-expandable metallic stent (CSEMS) is being increasingly used, but few studies have investigated risk factors for cholecystitis limited to CSEMS. The present study aimed to identify risk factors for cholecystitis after CSEMS. METHODS: Patients who underwent initial CSEMS placement for DBO between November 2014 and September 2021 were enrolled and followed-up until death, recurrent biliary obstruction, cholecystitis, or until March 2022...
September 12, 2023: Journal of Hepato-biliary-pancreatic Sciences
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JOURNAL ARTICLE
Kota Nakamura, Minako Nagai, Ippei Matsumoto, Sohei Satoi, Fuyuhiko Motoi, Manabu Kawai, Yasuo Hosouchi, Ryota Higuchi, Shugo Mizuno, Takao Ohtsuka, Keiichi Akahoshi, Kenichi Hakamada, Michiaki Unno, Hiroki Yamaue, Masafumi Nakamura, Itaru Endo, Masayuki Sho
BACKGROUND: We previously reported an association between antithrombotic therapy and an increased risk of postpancreatectomy hemorrhage (PPH). To validate our findings, we conducted a large-scale multicenter retrospective study from 63 high-volume centers in Japan. METHODS: Between 2015 and 2018, 7116 patients who underwent pancreatectomy were enrolled. The antithrombotic group consisted of 920 patients (12.9%) who received preoperative antithrombotic agents including aspirin, clopidogrel, ticlopidine, prasugrel, warfarin, and direct oral anticoagulants...
September 1, 2023: Journal of Hepato-biliary-pancreatic Sciences
#10
Haruka Toyonaga, Tsuyoshi Hayashi, Kazuki Hama, Kosuke Iwano, Ryo Ando, Tatsuya Ishii, Toshifumi Kin, Masayo Motoya, Kuniyuki Takahashi, Akio Katanuma
Toyonaga and colleagues demonstrate, with accompanying video, the use of low echo reduction, which is a novel endoscopic ultrasound function provided by a new endoscopic ultrasound processor that increases contrast without white-out. Low echo reduction might be useful in improving lesion boundaries and needle visibility during endoscopic ultrasound-guided tissue acquisition.
September 1, 2023: Journal of Hepato-biliary-pancreatic Sciences
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JOURNAL ARTICLE
Takahiro Tomino, Shinji Itoh, Daisuke Okamoto, Shohei Yoshiya, Yoshihiro Nagao, Noboru Harada, Nobuhiro Fujita, Yasuhiro Ushijima, Kousei Ishigami, Tomoharu Yoshizumi
PURPOSE: To evaluate the prognostic impact of dynamic gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) in patients with hepatocellular carcinoma (HCC). METHODS: We retrospectively reviewed the data of 206 patients with HCC who underwent preoperative Gd-EOB-DTPA-enhanced MRI and hepatectomy and quantitatively evaluated the signal intensity ratio of the tumor to the surrounding liver tissue in the portal phase (SIRPP)...
August 7, 2023: Journal of Hepato-biliary-pancreatic Sciences
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JOURNAL ARTICLE
Koya Yasukawa, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Hikaru Hayashi, Hidenori Tomida, Yudai Kuroiwa, Kenya Nakamura, Yuta Hongo, Yuji Soejima
BACKGROUND: The utility of the SAND balloon catheter in laparoscopic cholecystectomy for acute cholecystitis (AC) remains unclear. METHODS: A retrospective cohort study of patients who underwent emergency cholecystectomy at Shinshu University was performed to evaluate the efficacy of the SAND balloon catheter in cases of AC (SAND balloon utilization: Group S, n = 44; non-utilization: Group non-S, n = 47). RESULTS: The duration of surgery was significantly shorter in Group S than in Group non-S (p = ...
August 7, 2023: Journal of Hepato-biliary-pancreatic Sciences
#13
JOURNAL ARTICLE
Riki Asakura, Tetsuo Ajiki, Shigeki Abe, Hiroaki Yanagimoto, Daisuke Tsugawa, Shohei Komatsu, Tadahiro Goto, Sadaki Asari, Hirochika Toyama, Takumi Fukumoto
BACKGROUND: The exfoliative cell analyzer, LC-1000, is medical device that utilizes the principles of flow cytometry, and might provide digital diagnostic information for cytology using a different approach from conventional cytomorphology. In this study, wae examined the usefulness of the LC-1000 as a diagnostic support system for intraoperative peritoneal lavage cytology and its prognostic impact for pancreatic (PC) and biliary tract cancer (BTC). METHODS: Patients with PC and BTC who underwent surgical treatment were included...
August 7, 2023: Journal of Hepato-biliary-pancreatic Sciences
#14
JOURNAL ARTICLE
Akinori Maruta, Takuji Iwashita, Kensaku Yoshida, Keisuke Iwata, Shogo Shimizu, Masahito Shimizu
BACKGROUND: Endoscopic transpapillary naso-gallbladder drainage (ENGBD) has been reported to be an effective treatment option for acute cholecystitis. At our institution, ENGBD was first placed for external fistula management, and endoscopic internalization by cutting was performed, shifting to endoscopic transpapillary gallbladder stenting (EGBS) after improvement of cholecystitis. However, there has been no comparative study to define which preoperative management is better: converting ENGBD to EGBS or removing ENGBD...
June 19, 2023: Journal of Hepato-biliary-pancreatic Sciences
#15
JOURNAL ARTICLE
Takeo Nomi, Masaki Kaibori, Fumitoshi Hirokawa, Masaki Ueno, Daisuke Hokuto, Takehiro Noda, Takuya Nakai, Hisashi Ikoma, Hiroya Iida, Shoji Kubo
BACKGROUND: Delirium is a multifactorial and heterogeneous syndrome that is defined as acutely altered consciousness. This retrospective multicenter study evaluated the impact of postoperative delirium after liver resection for hepatocellular carcinoma (HCC) in elderly patients. METHODS: Patients aged ≥75 years, who underwent curative liver resection for HCC at nine university hospitals from April 2010 to December 2017, were evaluated to compare short- and long-term outcomes between patients with and without delirium...
June 16, 2023: Journal of Hepato-biliary-pancreatic Sciences
#16
JOURNAL ARTICLE
Takuya Minagawa, Osamu Itano, Shinichiro Hasegawa, Hiroshi Wada, Yuta Abe, Minoru Kitago, Yoshiteru Katsura, Yutaka Takeda, Tomohiko Adachi, Susumu Eguchi, Go Oshima, Satoshi Aiko, Yusuke Ome, Toshiki Kobayashi, Kazuki Hashida, Satoshi Nara, Minoru Esaki, Jota Watanabe, Hiromi Ohtani, Yutaka Endo, Takashi Shirobe, Yukio Tokumitsu, Hiroaki Nagano
BACKGROUND/PURPOSE: Laparoscopic resection of gallbladder carcinomas remains controversial. This study aimed to evaluate the surgical and oncological outcomes of laparoscopic procedures for suspected gallbladder carcinoma (GBC). METHODS: In this retrospective study, data regarding suspected GBC treated with laparoscopic radical cholecystectomy before 2020 in Japan, was included. Patient characteristics, surgical procedure details, surgical outcomes, and long-term outcomes were analyzed...
June 12, 2023: Journal of Hepato-biliary-pancreatic Sciences
#17
JOURNAL ARTICLE
Hirotaka Oura, Takayoshi Nishino, Daisuke Murakami, Yukiko Shima, Miho Shirato, Harutoshi Sugiyama, Makoto Arai
BACKGROUND: Patients with acute cholangitis (AC) have increased mortality when associated with bacteremia. This study aimed to evaluate the predictive ability of serum lactate (Lac) for positive bacteremia in patients with acute cholangitis. METHODS: In this single-center, retrospective study, 138 consecutive patients with AC were analyzed. Their blood samples were collected and Lac was measured. RESULTS: A total of 50 patients showed grade I, 50 showed grade II, and 38 showed grade III severity according to the Tokyo Guidelines 2018...
June 12, 2023: Journal of Hepato-biliary-pancreatic Sciences
#18
Takashi Horiuchi, Kenei Furukawa, Jungo Yasuda, Shinji Onda, Ryoga Hamura, Yoshihiro Shirai, Koichiro Haruki, Hironori Shiozaki, Takeshi Gocho, Toru Ikegami
Horiuchi and colleagues assessed the benefits of adding the Pringle maneuver to laparoscopic cholecystectomy for acute cholecystitis. Compared with laparoscopic cholecystectomy without the Pringle maneuver, including it reduced intraoperative bleeding. Laparoscopic cholecystectomy with the Pringle maneuver is a safe and feasible option that avoids conversion to open laparotomy and prevents serious complications.
May 2023: Journal of Hepato-biliary-pancreatic Sciences
#19
JOURNAL ARTICLE
Andrea Ruzzenente, Bernardo Dalla Valle, Edoardo Poletto, Nicholas L Syn, Tousif Kabir, Atsushi Sugioka, Federica Cipriani, Daniel Cherqui, Ho-Seong Han, Thomas Armstrong, Tran Cong Duy Long, Olivier Scatton, Paolo Herman, Johann Pratschke, Davit L Aghayan, Rong Liu, Marco V Marino, Adrian K H Chiow, Iswanto Sucandy, Arpad Ivanecz, Marco Vivarelli, Fabrizio Di Benedetto, Sung-Hoon Choi, Jae Hoon Lee, Mikel Prieto, Constantino Fondevila, Mikhail Efanov, Fernando Rotellar, Gi-Hong Choi, Ricardo Robles-Campos, Xiaoying Wang, Robert P Sutcliffe, Eric C H Lai, Charing C Chong, Mathieu D'Hondt, Chee Chien Yong, Roberto I Troisi, T Peter Kingham, Alessandro Ferrero, Giovanni Battista Levi Sandri, Olivier Soubrane, Mengqiu Yin, Santiago Lopez-Ben, Vincenzo Mazzaferro, Felice Giuliante, Kazateru Monden, Kohei Mishima, Go Wakabayashi, Tan-To Cheung, David Fuks, Mohammad Abu Hilal, Kuo-Hsin Chen, Luca Aldrighetti, Bjorn Edwin, Brian K P Goh
BACKGROUND: The aim of this multicentric study was to investigate the impact of tumor location and size on the difficulty of Laparoscopic-Left Hepatectomy (L-LH). METHODS: Patients who underwent L-LH performed across 46 centers from 2004 to 2020 were analyzed. Of 1236 L-LH, 770 patients met the study criteria. Baseline clinical and surgical characteristics with a potential impact on LLR were included in a multi-label conditional interference tree. Tumor size cut-off was algorithmically determined...
March 5, 2023: Journal of Hepato-biliary-pancreatic Sciences
#20
Kazunari Nakahara, Yosuke Michikawa, Junya Sato, Yosuke Igarashi, Akihiro Sekine, Yusuke Satta, Keisuke Tateishi
No abstract text is available yet for this article.
March 3, 2023: Journal of Hepato-biliary-pancreatic Sciences
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