Dawood Al Riyami, Saja Mohammed, Issa Al Salmi, AbdelMasiah Metry, Naifain Al Kalbani, Fathyia Almurshadi, Samira Al Rasbi, Faisal Al Ismaili, Alan Hola, Suad Hannawi
OBJECTIVES: Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening disease of chronic uncontrolled complement pathway activation that leads to thrombotic-microangiopathy, along with severe organ damage, including end-stage kidney disease. This study aimed to evaluate the epidemiology, management, and outcome of aHUS in an Omani population. METHODS: This retrospective descriptive cohort study assessed all cases of aHUS diagnosed and followed up at two tertiary care centers in Oman from January 2008 to December 2019, based on clinical features, complement pathway assays, histopathological, and genetic testing...
November 2023: Oman Medical Journal