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Journals Journal of Neurosurgery. Pedia...

Journal of Neurosurgery. Pediatrics

https://read.qxmd.com/read/38608307/responsive-neurostimulation-of-thalamic-nuclei-for-regional-and-multifocal-drug-resistant-epilepsy-in-children-and-young-adults
#1
JOURNAL ARTICLE
Deepankar Mohanty, Kimberly M Houck, Cristina Trandafir, Zulfi Haneef, Cemal Karakas, Steven Lee, Daniel J Curry, James J Riviello, Irfan Ali
OBJECTIVE: Responsive neurostimulation (RNS) is a US FDA-approved form of neuromodulation to treat patients with focal-onset drug-resistant epilepsy (DRE) who are ineligible for or whose condition is refractory to resection. However, the FDA approval only extends to use in patients with one or two epileptogenic foci. Recent literature has shown possible efficacy of thalamic RNS in patients with Lennox-Gastaut syndrome and multifocal epilepsy. The authors hypothesized that RNS of thalamic nuclei may be effective in seizure reduction for patients with multifocal or regionalized-onset DRE...
April 12, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38608297/indirect-revascularization-for-pediatric-moyamoya-disease
#2
JOURNAL ARTICLE
Shotaro Ogawa, Hideki Ogiwara
OBJECTIVE: Indirect revascularization is a common and effective treatment for pediatric moyamoya disease. However, in several cases postoperative angiogenesis is not sufficient. It is not fully understood which factors are involved in the development of postoperative collateral circulation. In this study, the authors aimed to elucidate the factors related to postoperative angiogenesis in indirect revascularization. METHODS: Among the patients who underwent indirect revascularization for moyamoya disease from January 2015 to December 2022, those whose angiogenesis was evaluated using angiography were included...
April 12, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38608296/ventricular-catheter-tissue-obstruction-and-shunt-malfunction-in-9-hydrocephalus-etiologies
#3
JOURNAL ARTICLE
Maria Garcia-Bonilla, Prashant Hariharan, Jacob Gluski, Miguel A Ruiz-Cardozo, Ayodamola Otun, Diego M Morales, Neena I Marupudi, William E Whitehead, Andrew Jea, Brandon G Rocque, James P McAllister, David D Limbrick, Carolyn A Harris
OBJECTIVE: Hydrocephalus is a neurological disorder with an incidence of 80-125 per 100,000 births in the United States. The most common treatment, ventricular shunting, has a failure rate of up to 85% within 10 years of placement. The authors aimed to analyze the association between ventricular catheter (VC) tissue obstructions and shunt malfunction for each hydrocephalus etiology. METHODS: Patient information was collected from 5 hospitals and entered into a REDCap (Research Electronic Data Capture) database by hydrocephalus etiology...
April 12, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38608292/machine-learning-for-enhanced-prognostication-predicting-30-day-outcomes-following-posterior-fossa-decompression-surgery-for-chiari-malformation-type-i-in-a-pediatric-cohort
#4
JOURNAL ARTICLE
Victor Gabriel El-Hajj, Abdul Karim Ghaith, Adrian Elmi-Terander, Edward S Ahn, David J Daniels, Mohamad Bydon
OBJECTIVE: Chiari malformation type I (CM-I) is a congenital disorder occurring in 0.1% of the population. In symptomatic cases, surgery with posterior fossa decompression (PFD) is the treatment of choice. Surgery is, however, associated with peri- and postoperative complications that may require readmission or renewed surgical intervention. Given the associated financial costs and the impact on patients' well-being, there is a need for predictive tools that can assess the likelihood of such adverse events...
April 12, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38579359/the-role-of-occipital-condyle-and-atlas-anomalies-on-occipital-cervical-fusion-outcomes-in-chiari-malformation-type-i-with-syringomyelia-a-study-from-the-park-reeves-syringomyelia-research-consortium
#5
JOURNAL ARTICLE
Alexander T Yahanda, Joyce Koueik, Laurie L Ackerman, P David Adelson, Gregory W Albert, Philipp R Aldana, Tord D Alden, Richard C E Anderson, David F Bauer, Tammy Bethel-Anderson, Karin Bierbrauer, Douglas L Brockmeyer, Joshua J Chern, Daniel E Couture, David J Daniels, Brian J Dlouhy, Susan R Durham, Richard G Ellenbogen, Ramin Eskandari, Herbert E Fuchs, Gerald A Grant, Patrick C Graupman, Stephanie Greene, Jeffrey P Greenfield, Naina L Gross, Daniel J Guillaume, Todd C Hankinson, Gregory G Heuer, Mark Iantosca, Bermans J Iskandar, Eric M Jackson, George I Jallo, James M Johnston, Bruce A Kaufman, Robert F Keating, Nickalus R Khan, Mark D Krieger, Jeffrey R Leonard, Cormac O Maher, Francesco T Mangano, Jonathan Martin, J Gordon McComb, Sean D McEvoy, Thanda Meehan, Arnold H Menezes, Michael S Muhlbauer, Brent R O'Neill, Greg Olavarria, John Ragheb, Nathan R Selden, Manish N Shah, Chevis N Shannon, Joshua S Shimony, Matthew D Smyth, Scellig S D Stone, Jennifer M Strahle, Mandeep S Tamber, James C Torner, Gerald F Tuite, Elizabeth C Tyler-Kabara, Scott D Wait, John C Wellons, William E Whitehead, Tae Sung Park, David D Limbrick, Raheel Ahmed
OBJECTIVE: Congenital anomalies of the atlanto-occipital articulation may be present in patients with Chiari malformation type I (CM-I). However, it is unclear how these anomalies affect the biomechanical stability of the craniovertebral junction (CVJ) and whether they are associated with an increased incidence of occipitocervical fusion (OCF) following posterior fossa decompression (PFD). The objective of this study was to determine the prevalence of condylar hypoplasia and atlas anomalies in children with CM-I and syringomyelia...
April 5, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38579357/the-impact-of-social-determinants-of-health-on-utilization-of-pediatric-epilepsy-surgery-a-systematic-review
#6
JOURNAL ARTICLE
Emily Winterhalter, Melissa A LoPresti, Elysa Widjaja, Aman Mohapatra, Nathan A Shlobin, Lu Zhang, Sandi Lam
OBJECTIVE: A minority of pediatric patients who may benefit from epilepsy surgery receive it. The reasons for this utilization gap are complex and not completely understood. Patient and caregiver social determinants of health (SDOH) may impact which patients undergo surgery and when. The authors conducted a systematic review examining SDOH and surgical intervention in children with drug-resistant epilepsy (DRE). They aimed to understand which factors influenced time to surgical program referral or receipt of epilepsy surgery among children with DRE, as well as identify areas to characterize the SDOH impacting epilepsy surgery in children and guide efforts aimed to promote health equity in epilepsy...
April 5, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38579347/clinical-and-socioeconomic-predictors-of-shunt-malfunction-in-the-pediatric-emergency-department
#7
JOURNAL ARTICLE
Kurt R Lehner, Rama J Alawneh, Ryan P Lee, Foad Kazemi, Joan Yea, Kelly Jiang, Anita L Kalluri, Eric M Jackson
OBJECTIVE: The aim of this study was to delineate the clinical and socioeconomic variables associated with shunt revision in pediatric patients presenting to the emergency department (ED) with concerns of ventricular shunt malfunction. METHODS: A retrospective analysis of pediatric ED consultations for shunt malfunction over a 1-year period was conducted, examining clinical symptoms, radiographic findings, and socioeconomic variables. Sensitivities, specificities, and positive and negative predictive values were calculated for each presenting symptom collected...
April 5, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38579345/resection-of-intradural-spinal-lesions-with-concomitant-instrumented-fusion-in-children-a-systematic-review-and-representative-cases
#8
JOURNAL ARTICLE
Kiana Y Prather, Matthew P Baier, Nangorgo J Coulibaly, Mark E Stephens, Sixia Chen, Michael E Omini, Andrew Jea
OBJECTIVE: More than one-third of pediatric patients who undergo resection of intradural spine lesions develop progressive postoperative deformity, with as many as half of these patients subsequently requiring surgical fusion. Intradural spinal procedures with simultaneous instrumented fusion in children, however, are infrequently performed. Moreover, the rationale for patient selection, outcomes, and safety of this single-stage surgery in children has not been systematically investigated...
April 5, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38552243/shunt-timing-in-low-weight-infants-in-the-treatment-of-hydrocephalus
#9
JOURNAL ARTICLE
Peter A Chiarelli, Nicholas Chapman, Benjamin E Flyer, Jason K Chu, Mark D Krieger
OBJECTIVE: The optimal timing of ventricular shunt placement in low-weight and preterm infants remains an unresolved topic in modern pediatric neurosurgery. Shunt placement for hydrocephalus is performed over a wide range of infant weights, and the standard weight threshold for shunt placement can vary substantially across institutions. The aim of this study was to investigate shunt outcome in infants of low body weight. METHODS: An IRB-approved retrospective analysis of 76 infants (29 females, 47 males) who received primary shunt placement between 2003 and 2018 was performed...
March 29, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38552237/adaptive-behavioral-and-emotional-outcomes-following-postoperative-pediatric-cerebellar-mutism-syndrome-in-survivors-treated-for-medulloblastoma
#10
JOURNAL ARTICLE
Kimberly P Raghubar, Andrew M Heitzer, Fatema Malbari, Jason Gill, Roy V Sillitoe, Livia Merrill, Johanna Escalante, M Fatih Okcu, Guillermo Aldave, Avner Meoded, Stephen Kralik, Kimberly Davis, Marina Ma, Emily A H Warren, Mark D McCurdy, Howard L Weiner, William Whitehead, Michael E Scheurer, Lisa Rodriguez, Amy Daigle, Murali Chintagumpala, Lisa S Kahalley
OBJECTIVE: Patients who experience postoperative pediatric cerebellar mutism syndrome (CMS) during treatment for medulloblastoma have long-term deficits in neurocognitive functioning; however, the consequences on functional or adaptive outcomes are unknown. The purpose of the present study was to compare adaptive, behavioral, and emotional functioning between survivors with and those without a history of CMS. METHODS: The authors examined outcomes in 45 survivors (15 with CMS and 30 without CMS)...
March 29, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38518281/association-between-structural-rib-autograft-and-the-rate-of-arthrodesis-in-children-undergoing-occiput-c2-instrumentation-and-fusion
#11
JOURNAL ARTICLE
Alexander Eremiev, David B Kurland, Alexander T M Cheung, Danielle Cook, Yosef Dastagirzada, David H Harter, Juan Rodriguez-Olaverri, Douglas Brockmeyer, Joshua M Pahys, Daniel Hedequist, Matthew Oetgen, Amer F Samdani, Richard C E Anderson
OBJECTIVE: The purpose of this study was to identify factors associated with fusion success among pediatric patients undergoing occiput-C2 rigid instrumentation and fusion. METHODS: The Pediatric Spine Study Group registry was queried to identify patients ≤ 21 years of age who underwent occiput-C2 posterior spinal rigid instrumentation and fusion and had a 2-year minimum clinical and radiographic (postoperative lateral cervical radiograph or CT scan) follow-up...
March 22, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38518279/language-discordant-care-in-pediatric-neurosurgery-parent-and-provider-perspectives-on-challenges-and-multilevel-solutions-to-reduce-disparities
#12
JOURNAL ARTICLE
Gabriela D Ruiz Colón, Sylvia Bereknyei Merrell, Diana C Poon, Kelly B Mahaney, Cormac O Maher, Laura M Prolo
OBJECTIVE: In the United States, Spanish is the second most spoken language, with nearly 42 million individuals speaking Spanish at home. Spanish speakers have been noted to have higher rates of unfavorable neurosurgical outcomes; however, to the authors' knowledge, no study has explored the experiences of patients, caregivers, and providers receiving or delivering neurosurgical care in language-discordant settings. In this study, the authors sought to identify challenges faced by pediatric neurosurgery providers and Spanish-speaking parents communicating with a language barrier and propose solutions to address those challenges...
March 22, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489820/neurocognitive-outcomes-and-associated-clinical-factors-5-years-after-surgery-in-children-with-craniosynostosis
#13
JOURNAL ARTICLE
Joo Whan Kim, Kyung Hyun Kim, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Byung Jun Kim, Jee Hyeok Chung, Min-Sup Shin, Seung-Ki Kim
OBJECTIVE: Craniosynostosis involves early closure of one or more sutures, which is known to limit normal cranium growth and interfere with normal brain development. Various surgical methods are used, ranging from minimally invasive strip craniectomy to more extensive whole-vault cranioplasty. This study aimed to evaluate neurocognitive outcomes 5 years after surgical treatment in children with craniosynostosis and to evaluate relevant clinical factors. METHODS: After exclusion of genetically confirmed syndromic craniosynostosis patients, a retrospective review was conducted on 112 nonsyndromic craniosynostosis patients who underwent surgical treatment and follow-up neurocognitive assessment...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489813/the-identification-of-risk-factors-and-outcomes-of-cerebrospinal-fluid-shunt-infections-caused-by-carbapenem-resistant-gram-negative-bacteria-in-children-a-retrospective-cohort
#14
JOURNAL ARTICLE
Gizem Guner Ozenen, Zumrut Sahbudak Bal, Elif Bolat, Zuhal Umit, Nimet M Bilen, Sema Yildirim Arslan, Tuncer Turhan, Feriha Cilli, Zafer Kurugol
OBJECTIVE: Cerebrospinal fluid (CSF) shunt infections caused by gram-negative bacteria are difficult to treat given the limited treatment options and the emergence of carbapenem-resistant (CR) strains. This study aimed to evaluate the demographic and clinical characteristics of children with CSF shunt and external ventricular drain (EVD) infections caused by gram-negative bacteria, to identify the risk factors for acquiring CR CSF shunt infections, and to report on the clinical outcomes of these infections...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489811/pediatric-brain-tumors-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#15
JOURNAL ARTICLE
Arsene Daniel Nyalundja, Ulrick Sidney Kanmounye, Claire Karekezi, Tsegazeab Laeke, Nqobile Thango, James A Balogun
OBJECTIVE: Brain tumors are a global problem, leading to higher cancer-related morbidity and mortality rates in children. Despite the progressive though slow advances in neuro-oncology care, research, and diagnostics in sub-Saharan Africa (SSA), the epidemiological landscape of pediatric brain tumors (PBTs) remains underestimated. This study aimed to systematically analyze the distribution of PBT types in SSA. METHODS: Ovid Medline, Global Index Medicus, African Journals Online, Google Scholar, and faculty of medicine libraries were searched for literature on PBTs in SSA published before October 29, 2022...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489810/natural-history-of-craniovertebral-abnormalities-in-a-single-center-study-in-54-patients-with-hurler-syndrome
#16
JOURNAL ARTICLE
Shiwei Huang, David R Nascene, Ryan Shanley, Isabela Pena-Pino, Troy C Lund, Ashish O Gupta, Paul J Orchard, Carolina Sandoval-Garcia
OBJECTIVE: Craniovertebral junction (CVJ) abnormalities are common and well documented in mucopolysaccharidosis type I-Hurler syndrome (MPS IH), often causing severe spinal canal narrowing. However, the requirement for surgical decompression and/or fusion is uncommon. Although hematopoietic cell transplant (HCT) has been shown to prolong the lives of patients with MPS IH, its effect in halting or reversing musculoskeletal abnormalities is less clear. Unfortunately, there are currently no universal guidelines for imaging or indication for surgical interventions in these patients...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489809/editorial-prolonged-survival-in-diffuse-midline-gliomas-a-socioeconomic-status-symbol-or-a-marker-of-good-supportive-care
#17
EDITORIAL
Michelle A Wedemeyer, Jeffrey Leonard
No abstract text is available yet for this article.
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38489807/influence-of-socioeconomic-status-on-clinical-outcomes-of-diffuse-midline-glioma-and-diffuse-intrinsic-pontine-glioma
#18
JOURNAL ARTICLE
John H Lee, Katherine G Holste, Momodou G Bah, Andrea T Franson, Hugh J L Garton, Cormac O Maher, Karin M Muraszko
OBJECTIVE: Given the lack of a definitive treatment and the poor prognosis of patients with diffuse midline glioma (DMG) and diffuse intrinsic pontine glioma (DIPG), socioeconomic status (SES) may affect treatment access and therefore survival. Therefore, this study aimed to examine the relationship between SES and treatment modalities, progression-free survival (PFS), and overall survival (OS) in children with DMG/DIPG. METHODS: A retrospective, single-institution review was conducted of medical records of patients ≤ 18 years of age who had DMG or DIPG that was diagnosed between 2000 and 2022...
March 15, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38457814/risk-factors-for-postoperative-ventriculoperitoneal-shunt-requirement-in-pediatric-patients-with-brain-tumors-invading-or-adjacent-to-csf-circulation-pathways
#19
JOURNAL ARTICLE
Zesheng Ying, Wei Yang, Nijia Zhang, Hailang Sun, Di Zhang, Baojin Shang, Jiashu Chen, Ming Ge
OBJECTIVE: Hydrocephalus is a common comorbidity of brain tumors in children that may persist following brain tumor resection. This study aimed to explore perioperative risk factors associated with postoperative ventriculoperitoneal shunt (VPS) placement for tumors located at or adjacent to the CSF circulation pathway. METHODS: Patients aged 0-18 years with tumors invading or adjacent to the CSF circulation pathways who underwent brain tumor resection between October 2015 and September 2021 were included in this study...
March 8, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38457812/predictors-and-timing-of-hydrocephalus-treatment-in-patients-undergoing-prenatal-versus-postnatal-surgery-for-myelomeningocele
#20
JOURNAL ARTICLE
Sasidhar Karuparti, Ashley Dunbar, Kaamya Varagur, Kavya Sudanagunta, Mark Mingo, Katherine H Bligard, Anthony Odibo, Jesse Vrecenak, Sean McEvoy, David Limbrick, Lindsay Peglar Marsala, Jagruti Anadkat, Ali Mian, Jennifer M Strahle
OBJECTIVE: Although hydrocephalus rates have decreased with intrauterine surgery for myelomeningocele (MMC), 40%-85% of children with MMC still go on to develop hydrocephalus. Prenatal ventricle size is known to be associated with later development of hydrocephalus; however, it is not known how prediction measures or timing of hydrocephalus treatment differ between pre- and postnatal surgery for MMC. The goal of this study was to determine anatomical, clinical, and radiological characteristics that are associated with the need for and timing of hydrocephalus treatment in patients with MMC...
March 8, 2024: Journal of Neurosurgery. Pediatrics
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