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Journals Journal of Neurosurgery. Pedia...

Journal of Neurosurgery. Pediatrics

https://read.qxmd.com/read/36964738/is-endoscope-assisted-strip-craniectomy-the-future-of-metopic-suture-craniosynostosis-treatment-an-11-year-experience-with-62-patients
#1
JOURNAL ARTICLE
Rina Agushi, Mirko Scagnet, Barbara Spacca, Regina Mura, Manuela Grandoni, Federico Mussa, Lorenzo Genitori
OBJECTIVE: Endoscopic mini-invasive treatment for sporadic trigonocephaly is becoming a widely accepted surgical treatment. In most centers this treatment is performed in association with postoperative helmeting. The aim of the present study was to review and report the authors' 11-year experience of endoscope-assisted metopic suturectomy for treatment of 62 trigonocephaly patients without helmet use. METHODS: For this retrospective study, clinical data of 62 consecutive pediatric patients (age 3-8 months) were obtained from the data bank of the "Anna Meyer" Children Hospital...
March 24, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36964731/a-prospective-study-of-prenatal-ventriculomegaly-natural-course-survival-and-neurodevelopmental-status
#2
JOURNAL ARTICLE
Sajedeh Karami, Ghazaleh Kheiri, Mohammad Mehdi Taghdiri, Amin Tavallaii, Keyvan Tayebi Meybodi, Zohreh Habibi, Farideh Nejat
OBJECTIVE: Prenatal ventriculomegaly (VM) is classified as mild, moderate, or severe on the basis of the diameter of the atrium. Neurodevelopmental status in prenatal VM is associated with various factors such as the course of VM, VM type, progression, and associated anomalies. In this study, the authors aimed to evaluate neurodevelopmental outcome in patients with prenatal VM and to detect possible associated risk factors. METHODS: In this study, 73 pregnancies with VM who were referred to Children's Medical Center, Tehran, Iran, between 2019 and 2021 were prospectively followed...
March 24, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36964730/the-significance-of-hindbrain-herniation-reversal-following-prenatal-repair-of-neural-tube-defects
#3
JOURNAL ARTICLE
Clifton O Brock, Eric P Bergh, Michal Fishel Bartal, Anthony Johnson, Edgar A Hernandez-Andrade, Jeannine Garnett, KuoJen Tsao, Mary T Austin, Stephen A Fletcher, Jennifer H Johnston, Katrina S Hughes, Rajan Patel, Ramesha Papanna
OBJECTIVE: The aim of this study was to determine whether reversal of hindbrain herniation (HBH) on MRI following prenatal repair of neural tube defects (NTDs) is associated with reduced rates of ventriculoperitoneal (VP) shunt placement or endoscopic third ventriculostomy (ETV) within the 1st year of life. METHODS: This is a secondary analysis of prospectively collected data from all patients who had prenatal open repair of a fetal NTD at a single tertiary care center between 2012 and 2020...
March 24, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36933267/safety-of-vagus-nerve-stimulation-and-responsive-neurostimulation-used-in-combination-for-multifocal-and-generalized-onset-epilepsy-in-pediatric-patients
#4
JOURNAL ARTICLE
Cameron P Beaudreault, Eris Spirollari, Alexandria F Naftchi, Vishad Sukul, Ankita Das, Sima Vazquez, Steven M Wolf, Patricia E McGoldrick, Carrie R Muh
OBJECTIVE: The aim of this study was to assess the safety and efficacy of combined active responsive neurostimulation (RNS) and vagus nerve stimulation (VNS) therapies in pediatric patients with drug-resistant epilepsy. METHODS: A single-center retrospective chart review was conducted on pediatric patients implanted with the RNS System with a concomitant active VNS System (VNS+RNS) between 2015 and 2021. Patients with at least 1 month of overlapping concomitant VNS and RNS treatment were included...
March 17, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36933266/mental-health-and-substance-use-disorders-in-young-adults-with-spina-bifida
#5
JOURNAL ARTICLE
Bao Y Sciscent, David R Hallan, Elias B Rizk
OBJECTIVE: Although medical advances have allowed most patients with spina bifida (SB) to survive into adulthood, these patients may have physical impairments, urological complications, infections, and neurocognitive deficits. These factors can cause psychological distress and impact the transition from pediatric to adult care. There remains limited research on mental health disorders (MHDs) and substance use disorders (SUDs) in SB patients during this vulnerable transition period. This study aimed to investigate the 10-year incidence of MHDs and SUDs in 18- to 25-year-old patients with SB...
March 17, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36933265/morning-glory-disc-anomaly-and-its-implications-in-moyamoya-arteriopathy-a-retrospective-case-series
#6
JOURNAL ARTICLE
Alfred P See, Melissa A LoPresti, Jeffrey Treiber, Brice Thomas, Madeline B Karsten, Coleman P Riordan, R Michael Scott, Sandi K Lam, Edward R Smith
OBJECTIVE: Morning glory disc anomaly (MGDA), a congenital abnormality of the optic nerve, may be associated with moyamoya arteriopathy, a cerebrovascular abnormality. In this study, the authors aimed to define the temporal evolution of cerebrovascular arteriopathy in patients with MGDA to characterize a rational strategy for screening and management over time. METHODS: The records of pediatric neurosurgical patients at two academic institutions were retrospectively reviewed to identify cases of cerebral arteriopathy and MGDA, including radiographic and clinical records documenting patient outcomes of medical and surgical management...
March 17, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36933264/from-fixed-pressure-paedigav-to-programmable-progav-prosa-serial-valves-for-pediatric-hydrocephalus-within-the-1st-year-of-life-a-technical-single-center-analysis
#7
JOURNAL ARTICLE
Fritz Teping, Matthias Huelser, Christoph Sippl, Michael Zemlin, Joachim Oertel
OBJECTIVE: Programmable valves have gained increasing popularity in the complex treatment of pediatric hydrocephalus. Over the last decade, adjustable serial valves have gradually replaced fixed-pressure valves in the authors' department. The present study investigates this development by analyzing shunt- and valve-related outcomes for this vulnerable population. METHODS: A retrospective analysis of all shunting procedures between January 2009 and January 2021 in children younger than 1 year of age was performed at the authors' single-center institution...
March 17, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36933263/the-natural-history-of-postoperative-hydrocephalus-after-pediatric-hemispherectomy-for-medically-refractory-epilepsy-an-institutional-experience
#8
JOURNAL ARTICLE
Victor M Lu, Shelly Wang, John Ragheb
OBJECTIVE: Hemispherectomy is a complex surgical intervention for medically refractory epilepsy, and its surgical sequelae continue to be defined. The incidence, timing, and predictors of postoperative hydrocephalus are not well understood. Correspondingly, the aim of this study was to define the natural history of the development of hydrocephalus after hemispherectomy based on the authors' institutional experience. METHODS: The authors performed a retrospective review of their departmental database for all relevant cases between 1988 and 2018...
March 17, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905673/association-of-novel-mutation-in-trpv4-with-familial-nonsyndromic-craniosynostosis-with-complete-penetrance-and-variable-expressivity
#9
JOURNAL ARTICLE
Tenzin Gayden, Gabriel Crevier-Sorbo, Wajih Jawhar, Christine Saint-Martin, Robert Eveleigh, Mirko S Gilardino, Natascia Anastasio, Yannis Trakadis, Angelia V Bassenden, Albert M Berghuis, Nada Jabado, Roy W R Dudley
OBJECTIVE: The aim of this study was to characterize a novel pathogenic variant in the transient receptor potential vanilloid 4 (TRPV4) gene, causing familial nonsyndromic craniosynostosis (CS) with complete penetrance and variable expressivity. METHODS: Whole-exome sequencing was performed on germline DNA of a family with nonsyndromic CS to a mean depth coverage of 300× per sample, with greater than 98% of the targeted region covered at least 25×. In this study, the authors detected a novel variant, c...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905672/letter-to-the-editor-the-molecular-mechanisms-of-folic-acid-fortification-to-prevent-spina-bifida
#10
LETTER
Juan Armando Mejía, Luis Garcia Rairan
No abstract text is available yet for this article.
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905671/cerebral-ischemia-a-frequent-complication-of-large-traumatic-epidural-hematoma-in-infants
#11
JOURNAL ARTICLE
Matthieu Landart, Sandro Benichi, Lelio Guida, Marilena Lazarescu, Marie Bourgeois, Hélène Sauvé-Martin, Raphael Levy, Charles-Joris Roux, Syril James, Timothée de Saint-Denis, Estelle Vergnaud, Giovanna Paternoster, Kevin Beccaria, Thomas Blauwblomme
OBJECTIVE: Epidural hematoma (EDH) has rarely been studied specifically in infants. The objective of this study was to investigate the outcomes of patients aged < 18 months (infants) with EDH. METHODS: The authors conducted a single-center retrospective study of 48 infants aged less than 18 months who underwent an operation for a supratentorial EDH in the last decade. Clinical, radiological, and biological variables were used in a statistical analysis to identify factors predictive of radiological and clinical outcome...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905670/persistent-discrepancies-in-orbital-morphology-after-surgical-treatment-of-unicoronal-craniosynostosis-a-critical-image-based-analysis
#12
JOURNAL ARTICLE
Hanna M Lif, Johan E Nysjö, Johan R Vegelius, Jesper Unander-Scharin, Per Enblad, Daniel J Nowinski
OBJECTIVE: Unicoronal craniosynostosis (UCS) is characterized by complex orbital deformity and is typically treated by asymmetrical fronto-orbital remodeling (FOR) during the 1st year of life. The aim of this study was to elucidate to what extent orbital morphology is corrected by surgical treatment. METHODS: The extent to which orbital morphology was corrected by surgical treatment was tested by analysis of differences in volume and shape between synostotic, nonsynostotic, and control orbits at two time points...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905669/variability-in-neurosurgical-management-and-associated-comorbidities-and-complications-among-preterm-patients-with-posthemorrhagic-hydrocephalus-in-the-united-states
#13
JOURNAL ARTICLE
Erwin Cabacungan, Samuel Adams, Benjamin Best, Andrew B Foy, Avantika Singh, Susan S Cohen
OBJECTIVE: Posthemorrhagic hydrocephalus (PHH) remains a major morbidity of premature birth resulting from intraventricular hemorrhage (IVH). National consensus guidelines for the timing of surgical interventions are lacking, which leads to considerable variations in management among neonatal intensive care units (NICUs). Early intervention (EI) has been shown to improve outcomes, but the authors hypothesized that the timing from IVH to intervention affects the comorbidities and complications associated with PHH management...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905668/efficacy-and-safety-of-bevacizumab-irinotecan-and-temozolomide-combination-for-relapsed-or-refractory-pediatric-central-nervous-system-embryonal-tumor-a-single-institution-study
#14
JOURNAL ARTICLE
Yoshiki Shiba, Kazuya Motomura, Rieko Taniguchi, Michihiro Kurimoto, Kosuke Mizutani, Fumiharu Ohka, Kosuke Aoki, Eiji Ito, Tomohide Nishikawa, Junya Yamaguchi, Yuji Kibe, Hiroki Shimizu, Sachi Maeda, Takuma Nakashima, Hiromichi Suzuki, Hideki Muramatsu, Yoshiyuki Takahashi, Ryuta Saito
OBJECTIVE: This study aimed to evaluate the efficacy and safety of combination therapy with bevacizumab (Bev), irinotecan (CPT-11), and temozolomide (TMZ) in children with central nervous system (CNS) embryonal tumor relapse. METHODS: The authors retrospectively examined 13 consecutive pediatric patients with relapsed or refractory CNS embryonal tumors who received combination therapy comprising Bev, CPT-11, and TMZ. Specifically, 9 patients had medulloblastoma, 3 had atypical teratoid/rhabdoid tumor (AT/RT), and 1 had CNS embryonal tumor with rhabdoid features...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36905667/cerebellar-tonsil-reduction-for-surgical-treatment-of-chiari-malformation-type-i-in-children
#15
JOURNAL ARTICLE
Bruno P Braga, Eric Y Montgomery, Bradley E Weprin, Angela V Price, Brett A Whittemore, Mark N Pernik, Frederick Sklar, Rafael De Oliveira Sillero, Dale M Swift
OBJECTIVE: The goal of this study was to review the efficacy and safety of different surgical techniques used for treatment of Chiari malformation type I (CM-I) in children. METHODS: The authors retrospectively reviewed 437 consecutive children surgically treated for CM-I. Procedures were classified into four groups: bone decompression (posterior fossa decompression [PFD]) and duraplasty (PFD with duraplasty [PFDD]), PFDD with arachnoid dissection (PFDD+AD), PFDD with tonsil coagulation of at least one cerebellar tonsil (PFDD+TC), and PFDD with subpial tonsil resection of at least one tonsil (PFDD+TR)...
March 10, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36883640/magnetic-resonance-imaging-guided-stereotactic-laser-ablation-therapy-for-the-treatment-of-pediatric-epilepsy-a-retrospective-multiinstitutional-study
#16
JOURNAL ARTICLE
Elsa V Arocho-Quinones, Sean M Lew, Michael H Handler, Zulma Tovar-Spinoza, Matthew D Smyth, Robert J Bollo, David Donahue, M Scott Perry, Michael Levy, David Gonda, Francesco T Mangano, Benjamin C Kennedy, Phillip B Storm, Angela V Price, Daniel E Couture, Chima Oluigbo, Ann-Christine Duhaime, Gene H Barnett, Carrie R Muh, Michael D Sather, Aria Fallah, Anthony C Wang, Sanjiv Bhatia, Daniel Eastwood, Sergey Tarima, Sarah Graber, Sean Huckins, Daniel Hafez, Kavelin Rumalla, Laurie Bailey, Sabrina Shandley, Ashton Roach, Erin Alexander, Wendy Jenkins, Deki Tsering, George Price, Antonio Meola, Wendi Evanoff, Eric M Thompson, Nicholas Brandmeir
OBJECTIVE: The authors of this study evaluated the safety and efficacy of stereotactic laser ablation (SLA) for the treatment of drug-resistant epilepsy (DRE) in children. METHODS: Seventeen North American centers were enrolled in the study. Data for pediatric patients with DRE who had been treated with SLA between 2008 and 2018 were retrospectively reviewed. RESULTS: A total of 225 patients, mean age 12.8 ± 5.8 years, were identified...
March 3, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36883637/editorial-neurocognition-in-fetal-myelomeningocele-closure-not-shunting-per-se
#17
EDITORIAL
Jeffrey P Blount, Brandon G Rocque
No abstract text is available yet for this article.
March 3, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36883636/establishing-language-laterality-does-resting-state-functional-mri-help
#18
JOURNAL ARTICLE
Sumit Singh, Mustafa S M Alhasan, Zhiyue Wang, Rebekah Clarke, Yin Xi, Joseph A Maldjian, Ben Wagner, Timothy Booth
OBJECTIVE: Task-based functional MRI (tb-fMRI) is now considered the standard, noninvasive technique in establishing language laterality in children for surgical planning. The evaluation can be limited due to several factors such as age, language barriers, and developmental and cognitive delays. Resting-state functional MRI (rs-fMRI) offers a potential path to establish language dominance without active task participation. The authors sought to compare the ability of rs-fMRI for language lateralization in the pediatric population with conventional tb-fMRI used as the gold standard...
March 3, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36883627/hydrocephalus-and-school-age-neurodevelopmental-outcomes-in-the-management-of-myelomeningocele-prenatal-surgery-trial-a-secondary-analysis
#19
JOURNAL ARTICLE
Jack M Fletcher, Amy J Houtrow, Cora MacPherson, Nina H Thomas, Nalin Gupta, N Scott Adzick, Elizabeth A Thom
OBJECTIVE: The purpose of this secondary analysis was to assess the role of hydrocephalus on neurodevelopmental outcomes in a cohort of school-age children enrolled in the Management of Myelomeningocele Study (MOMS) clinical trial. METHODS: The sample analyzed in this report consisted of 150 of 183 children aged 5-10 years (mean ± SD 7 years 8 months ± 1.2) who were randomly assigned between 20 and 26 weeks of gestational age to undergo either prenatal or postnatal surgery and were enrolled in the school-age follow-up study of MOMS...
March 3, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/36883624/parental-sensitivity-and-specificity-to-recognize-shunt-malfunction-in-their-child-a-single-center-prospective-study
#20
JOURNAL ARTICLE
Amparo Saenz, Santiago Cicutti, Romina Argañaraz, Beatriz Mantese, Diego Giunta
OBJECTIVE: The objective of this study was to estimate the diagnostic performance (sensitivity, specificity, positive predictive value, and negative predictive value) for recognizing ventriculoperitoneal shunt (VPS) failure in the parents of patients 0-18 years of age who attended the hospital's emergency room (ER). The second objective was to identify the factors associated with the parents' ability to recognize the shunt blockage (true positives). METHODS: A prospective cohort study was conducted between 2021 and 2022 including all patients 0-18 years of age who had a VPS and attended the hospital's ER with symptoms that could correspond to VPS blockage...
March 3, 2023: Journal of Neurosurgery. Pediatrics
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