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https://read.qxmd.com/read/30758400/allele-and-haplotype-frequencies-of-human-platelet-and-leukocyte-antigens-in-platelet-donors
#1
Valeria de Freitas Dutra, Carolina Bonet Bub, Thiago Henrique Costa, Leandro Dinalli Santos, Eduardo Peres Bastos, Maria Giselda Aravechia, José Mauro Kutner
OBJECTIVE: To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood. METHODS: We included 867 healthy unrelated volunteer donors who donated platelets between January 2011 and December 2014. Microarray genotyping was performed using a BeadChip microarray. Medium resolution typing of the human leukocyte antigen at loci A and B was carried out using sequence-specific oligonucleotide probe hybridization...
February 7, 2019: Einstein
https://read.qxmd.com/read/30758399/assessing-how-emergency-and-trauma-ultrasonography-is-taught-to-medical-students
#2
José Cruvinel Neto, Vinicius Rinaldi Vieira Marcondes, Marcelo Augusto Fontenelle Ribeiro Junior
OBJECTIVE: To evaluate a method aimed at teaching ultrasound techniques to medical students in emergency settings. METHODS: A prospective study conducted with 66 sixth-year undergraduate medical students. Students participated in theory and practicing sessions with a 5-hour load; knowledge acquisition was assessed through pre- and post-course and 90-day tests. A questionnaire were distributed to the students after course completion for theoretical and practical knowledge assessment...
February 7, 2019: Einstein
https://read.qxmd.com/read/30758398/evaluation-of-the-quality-of-primary-health-care-services-for-children-reflections-on-the-feasibility-of-using-the-brazilian-version-of-the-primary-care-assessment-tool-as-a-routine-assessment-tool
#3
Liz Ponnet, Sara Willems, Veerle Vyncke, Aylene Emilia Moraes Bousquat, Ana Luiza d'Ávila Viana, Guilherme Arantes Mello, Marcelo Demarzo
OBJECTIVE: To assess the quality of the Primary Health Care services provided to children and the feasibility of using the Brazilian version of Primary Care Assessment Tool (PCAT-Brazil) as a routine quality assessment tool. METHODS: A cross-sectional study was carried out in Joanópolis, a small rural town in the State of São Paulo (SP), Brazil. Seven health professionals and 502 caretakers of children using the public health center were interviewed using the PCAT-Brazil, collecting data on the core and related attributes of Primary Health Care provided to children...
February 7, 2019: Einstein
https://read.qxmd.com/read/30726310/streptococcus-mutans-detection-in-saliva-and-colostrum-samples
#4
Camilla Beatriz da Silva, Marcelly Milhomem Mendes, Bárbara Rocha Rodrigues, Thiago Lima Pereira, Denise Bertulucci Rocha Rodrigues, Virmondes Rodrigues Junior, Virginia Paes Leme Ferriani, Vinicius Rangel Geraldo-Martins, Ruchele Dias Nogueira
OBJECTIVE: To detect Streptococcus mutans in colostrum and saliva of neonates and compare with its detection in saliva of mothers. METHODS: Forty-three healthy women, full-term gestations with no complications, submitted to elective Cesarean section, and their newborns were included in the study. Samples were investigated by polymerase chain reaction to detect S. mutans in genetic material from the samples. RESULTS: Approximately 16% of colostrum samples showed S...
January 31, 2019: Einstein
https://read.qxmd.com/read/30726309/association-between-respiratory-capacity-quality-of-life-and-cognitive-function-in-elderly-individuals
#5
Rayana de Oliveira Costa, Raphael Mendes Ritti-Dias, Gabriel Grizzo Cucato, Maysa Seabra Cendoroglo, Fabio Nasri, Maria Luiza Monteiro Costa, Luciana Diniz Nagem Janot de Matos, Fábio Gazelato de Mello Franco
OBJECTIVE: To investigate associations between respiratory capacity, quality of life and cognitive function in elderly individuals. METHODS: The sample included 386 elderly individuals (232 women). Respiratory capacity assessment was based on maximal expiratory pressure measured at peak expiratory flow. Subjects were classified according to peak expiratory flow values adjusted for sex, age and height of individuals with normal (peak expiratory flow curve <80% and >60%) or reduced (peak expiratory flow curve < 60%) respiratory capacity...
January 31, 2019: Einstein
https://read.qxmd.com/read/30726308/sellar-and-suprasellar-arachnoid-cyst
#6
João Mangussi-Gomes, André Felix Gentil, Renée Zon Filippi, Rafael Almeida Momesso, Benjamin Wolf Handfas, João Radvany, Leonardo Balsalobre, Aldo Cassol Stamm
No abstract text is available yet for this article.
January 31, 2019: Einstein
https://read.qxmd.com/read/30673055/leadership-potential-of-physicians-in-a-public-teaching-hospital-in-the-city-of-s%C3%A3-o-paulo
#7
Alexandre Fioranelli, Charles Schmidt, Nelson Wolosker, Valter Castelli Júnior, Dafne Braga Diamante Leiderman, Luiz Arnaldo Szutan
OBJECTIVE: To analyze the leadership potential of physicians in a public hospital in the city of São Paulo. METHODS: A descriptive pilot study, in which 40 assistant physicians and medical residents were randomly selected to receive an electronic invitation of the company Caliper Estratégias Humanas do Brasil . To those who accepted it, a link was sent to fill out a personality evaluation focused on the work, comprising 112 alternatives related to 21 domains of 4 performance areas...
January 21, 2019: Einstein
https://read.qxmd.com/read/30673054/prevalence-of-g6pd-deficiency-and-molecular-characterization-of-g202a-a376g-and-c563t-polymorphisms-in-newborns-in-southeastern-brazil
#8
Lucas Luís Meigre Dias Pereira, Cristina Augusta Bravin, Terezinha Sarquis Cintra, Wélida Santos Portela Cassa, Thainá Altoé Santos, Armando Fonseca, Rodrigo Pratte-Santos
OBJECTIVE: To evaluate the prevalence of G6PD deficiency and characterize G202A, A376G and C563T polymorphisms in neonates using molecular assays. METHODS: A total of one thousand samples were tested through quantitative analysis of enzyme activity, detecting 25 G6PD-deficient individuals. Patients identified as deficient were submitted to molecular analysis quantitative real-time polymerase chain reaction - (qPCR) to investigate the presence of variants associated with the deficiency...
January 21, 2019: Einstein
https://read.qxmd.com/read/30673053/hormone-receptor-negative-as-a-predictive-factor-for-pathologic-complete-response-to-neoadjuvant-therapy-in-breast-cancer
#9
Luana Carolina Ferreira Fiuza Silva, Lilian Silva Martins de Arruda, Waldec Jorge David Filho, Felipe José Silva Melo Cruz, Damila Cristina Trufelli, Auro Del Giglio
OBJECTIVE: To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free survival. METHODS: A retrospective study of patients admitted to Hospital Estadual Mário Covas and Hospital Anchieta from 2008 to 2012, with locally advanced breast cancer...
January 21, 2019: Einstein
https://read.qxmd.com/read/30652738/effects-of-overnight-fasting-on-handgrip-strength-in-inpatients
#10
Wesley Santana Correa-Arruda, Iara Dos Anjos Vaez, José Eduardo Aguilar-Nascimento, Diana Borges Dock-Nascimento
OBJECTIVE: To investigate the effects of overnight fasting on handgrip strength of adult inpatients. METHODS: A prospective clinical study enrolling 221 adult patients. The endpoints were handgrip strength obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative handgrip strength (mean of handgrip strength after breakfast and lunch) in the same day. The mean of three handgrip strength measures was considered to represent each time point...
January 14, 2019: Einstein
https://read.qxmd.com/read/30652737/comparison-of-the-neutrophil-to-lymphocyte-and-platelet-to-lymphocyte-ratios-in-normoglycemic-and-hyperglycemic-subjects
#11
Brena Barros Mendes, Anniely Carvalho Rebouças Oliveira, Keila Correia de Alcântara
OBJECTIVE: To compare the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as possible parameters of systemic inflammation in hyperglycemic and normoglycemic subjects. METHODS: A retrospective, cross-sectional study of data collected from patients tested for fasting blood glucose, glycated hemoglobin (HbA1c) and blood count on the same day, between July and December 2016. Patients were divided into hyperglycemic and normoglycemic, and matched by age and sex...
January 14, 2019: Einstein
https://read.qxmd.com/read/30652736/influence-of-parental-smoking-on-the-use-of-alcohol-and-illicit-drugs-among-adolescents
#12
Luciano Machado Ferreira Tenório de Oliveira, Ana Raquel Mendes Dos Santos, Breno Quintella Farah, Raphael Mendes Ritti-Dias, Clara Maria Silvestre Monteiro de Freitas, Paula Rejane Beserra Diniz
OBJECTIVE: To evaluate the association between parental smoking and the use of alcohol and illicit drugs among adolescent children. METHODS: A cross-sectional study with 6,264 adolescents (59.7% female) aged between 14 and 19 years. To establish the sample, we used two-stage cluster random sampling. The data on parental smoking and use of cigarettes, alcohol and illicit drugs among adolescents were collected using a questionnaire. RESULTS: Smoking adolescents were more prone to use alcohol (odds ratio - OR: 10...
January 14, 2019: Einstein
https://read.qxmd.com/read/30569953/when-color-helps
#13
Ana Luiza Fontes de Azevedo Costa, Thiago Gonçalves Dos Santos Martins, Ricardo Vieira Martins, Paulo Schor
OBJECTIVE: To reduce the inappropriate identification of eye drops, through the use of different colors. METHODS: A group of 34 healthy volunteers was presented to two groups of four eye drops each. All eye drops were placed in identical, unlabelled vials. In one group, all four eye drops were transparent. In the other group, each had a different color. A number was assigned to each eye drop, and the volunteer was asked to identify it by color. We measured the correct index in the identification of the eye drops of the two groups...
December 17, 2018: Einstein
https://read.qxmd.com/read/30569952/challenge-in-the-diagnosis-of-pulmonary-strongyloidiasis
#14
Andrea Dos Santos Pereira, Alexandre Gimenes Marques, André Mario Doi, Marinês Dalla Valle Martino, Paula Célia Mariko Koga, Vivian Renata Chiarato, Liang Fung, Rima Batah Martins, Jacyr Pasternak
No abstract text is available yet for this article.
December 17, 2018: Einstein
https://read.qxmd.com/read/30540032/mindfulness-based-stress-reduction-on-breast-cancer-symptoms-systematic-review-and-meta-analysis
#15
Flavia Del Castanhel, Rafaela Liberali
Mindfulness-Based Stress Reduction practices increase the capacity for concentration and attention, and these practices are particularly effective for people with breast cancer. To analyze the effects of the application of Mindfulness-Based Stress Reduction on breast cancer symptoms. Systematic review and meta-analysis were carried out. To find suitable studies, the PubMed/ MEDLINE database was searched using the keywords "breast cancer" and "Mindfulness-Based Stress Reduction". Studies included were published between 2013 and 2017, written in English and showed methodological quality through the PEDro scale (score greater than 3)...
December 6, 2018: Einstein
https://read.qxmd.com/read/30517370/severe-iron-deficiency-anemia-as-initial-manifestation-of-pulmonary-hemosiderosis-in-a-child
#16
Natália Noronha, Pedro Ramalho, Rogério Barreira, Juliana Roda, Teresa Reis Silva, Miguel Félix
Idiopathic pulmonary hemosiderosis is a potentially fatal disease that results from episodes of alveolar hemorrhage of unknown origin. The clinical spectrum is varied, and anemia may constitute the only manifestation of illness, preceding other signs and symptoms by several months. We present the case of a 4 year-old child presenting with fever, vomiting and prostration, associated with pallor. He had microcytic and hypochromic anemia refractory to iron therapy. Gastrointestinal bleeding was ruled out after negative extensive etiological investigation...
November 29, 2018: Einstein
https://read.qxmd.com/read/30517369/nanotechnology-and-multipotent-adult-progenitor-cells-in-reparative-medicine-therapeutic-perspectives
#17
Angela Mazzeo, Enrico Jardim Clemente Santos
The biology of stem cells is one of the most dynamic and promising fields of the biological sciences, since it is the basis for the development of organisms. Its biological complexity demands efforts from several lines of research aimed mainly at its therapeutic use. Nanotechnology has been emerging as a new field of study, which shows great potential in the treatment of various diseases. This new area of health has been called "Nanomedicine" or "Bionanotechnology", which can be applied in Medicine by transport and drug delivery systems, robotic tools to be used in diagnostic and surgical processes, nanobiomaterials, gene therapies, nanobiomedical devices, among others...
November 29, 2018: Einstein
https://read.qxmd.com/read/30517368/what-is-the-future-of-the-brazilian-public-health-system
#18
EDITORIAL
Jacyr Pasternak
No abstract text is available yet for this article.
November 29, 2018: Einstein
https://read.qxmd.com/read/30517367/polyclonal-anti-t-lymphocyte-antibody-therapy-monitoring-in-kidney-transplant-recipients-comparison-of-cd3-t-cell-and-total-lymphocyte-counts
#19
Fabiani Palagi Machado, Alessandra Rosa Vicari, Fábio Spuldaro, João Batista Saldanha de Castro Filho, Roberto Ceratti Manfro
OBJECTIVE: To investigate the correlation between total lymphocyte and CD3+ T cell counts in peripheral blood in renal transplant patients treated with anti-thymocyte globulin, and discuss related outcomes. METHODS: A single-center, retrospective study involving 226 patients submitted to kidney transplant between 2008 and 2013, and treated with anti-thymocyte globulin for induction or treatment of cellular rejection. Doses were adjusted according to CD3+ T cell or total lymphocyte counts in peripheral blood...
November 29, 2018: Einstein
https://read.qxmd.com/read/30517366/facial-nerve-hemangioma-in-the-middle-ear
#20
Ludmilla Emilia Martins Costa, Rafael Freire de Castro, Fabiolla Maria Martins Costa, Mônica Alcântara de Oliveira Santos
Facial nerve hemangioma is a rare and benign vascular tumor, and accounts for 0.7% of intratemporal tumors. We report the second case described in the literature of a facial nerve hemangioma in its tympanic segment. A 14-year-old male patient presented with a history of progressive right ear hearing loss with preserved facial mimicry. Pure tone audiometry showed a right ear moderate conductive hearing loss. Magnetic resonance imaging demonstrated an expansive lesion involving the tympanic segment of the right facial nerve, suggestive of hemangioma...
November 29, 2018: Einstein
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