Pavan K Bhatraju, Leila R Zelnick, Ian B Stanaway, T Alp Ikizler, Steven Menez, Vernon M Chinchilli, Steve G Coca, James S Kaufman, Paul L Kimmel, Chirag R Parikh, Alan S Go, Edward D Siew, Mark M Wurfel, Jonathan Himmelfarb
BACKGROUND: Cognitive dysfunction is a well-known complication of chronic kidney disease, but it is less known whether cognitive decline occurs in survivors after acute kidney injury (AKI). We hypothesized that an episode of AKI is associated with poorer cognitive function, mediated, at least in part, by persistent systemic inflammation. METHODS: ASSESS-AKI enrolled patients surviving three months after hospitalization with and without AKI matched based on demographics, comorbidities, and baseline kidney function...
May 10, 2024: Clinical Journal of the American Society of Nephrology: CJASN