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Clinical Journal of the American Society of Nephrology : CJASN

https://read.qxmd.com/read/38985525/supporting-fellows-during-pregnancy-improvement-is-needed
#1
JOURNAL ARTICLE
Natalie Freidin, Ruth C Campbell
No abstract text is available yet for this article.
July 10, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38980732/sodium-bicarbonate-treatment-and-clinical-outcomes-in-chronic-kidney-disease-with-metabolic-acidosis-a-meta-analysis
#2
JOURNAL ARTICLE
Ting-Ya Yang, Hong-Min Lin, Hsien-Yi Wang, Min-Hsiang Chuang, Chia-Chen Hsieh, Kang-Ting Tsai, Jui-Yi Chen
BACKGROUND: In patients with chronic kidney disease (CKD), impaired kidney acid excretion leads to the onset of metabolic acidosis (MA). However, the evidence is not yet conclusive regarding the effects of sodium bicarbonate in treating CKD with MA. METHODS: Databases with PubMed, Embase, and the Cochrane Library were used to search for randomized controlled trials from the inception until November 11, 2023 to identify randomized controlled trials investigating the effect of sodium bicarbonate in participants with CKD and MA...
July 9, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38980722/understanding-the-bp-lowering-mechanism-of-chlorthalidone-in-advanced-kidney-disease
#3
JOURNAL ARTICLE
Tazeen H Jafar, Liang Feng
No abstract text is available yet for this article.
July 9, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38967973/primary-distal-renal-tubular-acidosis-towards-an-optimal-correction-of-metabolic-acidosis
#4
JOURNAL ARTICLE
Elba Medina, Gema Ariceta, Daniel Batlle
The term classic, type I renal tubular acidosis (RTA) or primary distal RTA is used to designate patients with impaired ability to excrete acid normally in the urine as a result of tubular transport defects involving type A intercalated cells in the collecting duct. The clinical phenotype is largely characterized by the complications of chronic metabolic acidosis, stunted growth, bone abnormalities, as well as nephrocalcinosis and nephrolithiasis that develop as the consequence of hypercalciuria and hypocitraturia...
July 5, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38954482/supporting-self-management-of-healthy-behaviors-in-chronic-kidney-disease-and-hypertension-the-smart-habits-pilot-randomized-trial
#5
JOURNAL ARTICLE
Sarah J Schrauben, Diane Park, Sandra Amaral, Adriana Purcell, Siqi Zhang, Matthew Kearney, Andrea Bilger, Harold I Feldman, Laura M Dember
BACKGROUND: Support programs for self-management are under-utilized among people with chronic kidney disease (CKD). We examined the feasibility of a smartphone-based intervention to support physical activity and blood pressure monitoring, Supporting Self-Management of Healthy Behaviors (SMART-HABITS), for individuals with CKD and hypertension. METHODS: SMART-HABITS was piloted in a 12-week randomized cross-over trial among people with CKD and hypertension. Participants were asked to monitor blood pressure ≥3-times/week and step counts ≥5-times/week...
July 2, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38949880/frailty-multimorbidity-and-polypharmacy-exploratory-analyses-of-the-effects-of-empagliflozin-from-the-empa-kidney-trial
#6
JOURNAL ARTICLE
Kaitlin J Mayne, Rebecca J Sardell, Natalie Staplin, Parminder K Judge, Doreen Zhu, Emily Sammons, David Zi Cherney, Alfred K Cheung, Aldo P Maggioni, Masaomi Nangaku, Xavier Rossello, Katherine R Tuttle, Katsuhito Ihara, Tomoko Iwata, Christoph Wanner, Jonathan Emberson, David Preiss, Martin J Landray, Colin Baigent FMedSci, Richard Haynes, William G Herrington
BACKGROUND: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are recommended treatment for adults with chronic kidney disease (CKD), but uncertainty exists regarding their use in patients with frailty and/or multimorbidity, among whom polypharmacy is common. We derived a multivariable logistic regression model to predict hospitalization (reflecting frailty) and assessed empagliflozin's risk-benefit profile in a post-hoc analysis of the double-blind, placebo-controlled EMPA-KIDNEY trial...
July 1, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38922691/infection-related-glomerulonephritis-with-cutaneous-vasculitis
#7
JOURNAL ARTICLE
Jodi Gedallovich, Ralph M Mohty, Ksenia Kasimova, Zhengchun Lu, Vivek Charu, John P Higgins Jp, Neeraja Kambham, Vanderlene L Kung, Megan L Troxell
No abstract text is available yet for this article.
June 26, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38922689/twice-weekly-versus-thrice-weekly-hemodialysis-a-pilot-cross-over-equivalence-trial
#8
JOURNAL ARTICLE
Seolhyun Lee, Nhat M Pham, Maria E Montez-Rath, Christian G Bolanos, Saniya S Bonde, Timothy W Meyer, Tammy L Sirich
BACKGROUND: The 2015 Update of the Kidney Disease Outcomes Quality Initiative (KDOQI) Guideline for Hemodialysis Adequacy increased the contribution of residual kidney function in calculating standard Kt/V urea (stdKt/V urea ). However, no study has assessed the effect of prescribing twice weekly hemodialysis according to this guideline on patients' quality of life or uremic solute levels. METHODS: Twenty six hemodialysis patients with average residual urea clearance (Kru) 4...
June 26, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38913442/sleep-disorders-and-dementia-risk-in-older-patients-with-kidney-failure-a-retrospective-cohort-study
#9
JOURNAL ARTICLE
Jane J Long, Yusi Chen, Byoungjun Kim, Sunjae Bae, Yiting Li, Babak J Orandi, Nadia M Chu, Aarti Mathur, Dorry L Segev, Mara A McAdams-DeMarco
BACKGROUND: Community-dwelling older adults with sleep disorders are at higher risk of developing dementia. Greater than 50% of older patients with kidney failure experience sleep disorders, which may explain their high burden of dementia. METHODS: Among 216,158 patients (age ≥66 years) with kidney failure (United States Renal Data System; 2008-2019), we estimated the risk of dementia (including subtypes) associated with sleep disorders using Cox proportional-hazard models with propensity score weighting...
June 24, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38913437/replacement-strategies-for-tunneled-hemodialysis-catheters-with-complications-a-nationwide-cohort-study
#10
JOURNAL ARTICLE
Benjamin Lazarus, Sradha Kotwal, Martin Gallagher, Nicholas A Gray, Sarah Coggan, Girish Talaulikar, Kevan R Polkinghorne
BACKGROUND: Tunneled hemodialysis catheters often have infectious or mechanical complications that require unplanned removal and replacement, but the optimal replacement strategy is unknown. This study described the real-world use of two strategies in Australia and compared the survival of replacement catheters inserted by either strategy. METHODS: Observational data from the REDUCCTION trial, which enrolled a nationwide cohort of 6400 adults who received an incident hemodialysis catheter (2016-2020) was used for this secondary analysis...
June 24, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38913426/a-case-of-the-non-caseating-granuloma
#11
JOURNAL ARTICLE
Dia R Waguespack
No abstract text is available yet for this article.
June 24, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38905219/validation-of-non-invasive-detection-of-hyperkalemia-by-artificial-intelligence-enhanced-electrocardiography-in-high-acuity-settings
#12
JOURNAL ARTICLE
David M Harmon, Kan Liu, Jennifer Dugan, Jacob C Jentzer, Zachi I Attia, Paul A Friedman, John J Dillon
BACKGROUND: Artificial intelligence (AI) electrocardiogram (ECG) analysis can enable detection of hyperkalemia. In this validation, we assessed the algorithm's performance in two high acuity settings. METHODS: An emergency department (ED) cohort (February-August 2021) and a mixed intensive care unit (ICU) cohort (August 2017-February 2018) were identified and analyzed separately. For each group, pairs of laboratory-collected potassium and 12 lead ECGs obtained within four hours of each other were identified...
June 21, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38902862/lessons-learned-from-hera-the-first-alport-syndrome-therapeutic-clinical-trial
#13
JOURNAL ARTICLE
B André Weinstock
No abstract text is available yet for this article.
June 21, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38888965/a-six-year-follow-up-of-bloodstream-infections-in-hemodialysis-facilities-in-the-united-states-national-healthcare-safety-network-2020
#14
JOURNAL ARTICLE
John Keenan, Kira A Barbre, Philip Dollard, Tamara Hoxworth, Iram Qureshi, Lindsay Dunham, Erin O'Leary, Selom Agbobli Nuwoaty, Suparna Bagchi, Jonathan Edwards, Mary Lu, Andrea Benin, Jeneita Bell
METHODS: Outpatient hemodialysis facilities report BSI events to NHSN. Pooled mean rates with 95% CI were calculated overall and for each type of vascular access (arteriovenous (AV) fistula, AV graft, or a central venous catheter (CVC)). Standardized infection ratios were calculated as observed BSI events divided by the predicted number of events based on national aggregate data. Median facility-level standardized infection ratios and 95% confidence intervals (CIs) were stratified by state and US territory...
June 18, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38869950/comparison-of-cardiac-autonomic-innervation-in-post-mortem-tissue-from-individuals-with-kidney-failure-and-preserved-kidney-function
#15
JOURNAL ARTICLE
Qandeel Soomro, Valeria Mezzano, Navneet Narula, Amy Rapkiewicz, Cynthia Loomis, David M Charytan
No abstract text is available yet for this article.
June 13, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38865199/mechanisms-of-antihypertensive-effect-of-chlorthalidone-in-advanced-chronic-kidney-disease-a-causal-mediation-analysis
#16
JOURNAL ARTICLE
Rajiv Agarwal, Arjun D Sinha, Wanzhu Tu
BACKGROUND: Chlorthalidone in chronic kidney disease (CLICK) randomized trial demonstrated a robust reduction in systolic blood pressure (BP) in stage 4 chronic kidney disease (CKD). Here we explore the mechanisms underlying the antihypertensive effect of chlorthalidone. METHODS: In this prespecified analysis, we analyzed the contributions of baseline levels of 24-hour urinary sodium and aldosterone and the changes from baseline to 4 weeks in the multiple mediators reflecting volume status in a causal mediation analysis framework...
June 12, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38865196/patient-and-caregiver-perspective-on-pro-kid-quality-of-life-tool
#17
JOURNAL ARTICLE
Lisa Bonebrake, Afton DeLucca
No abstract text is available yet for this article.
June 12, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38865192/how-we-treat-dyslipidemia-in-prolonged-nephrotic-syndrome
#18
JOURNAL ARTICLE
Claudio Ponticelli, Lorenzo Arnaboldi, Gabriella Moroni, Alessia Fornoni
No abstract text is available yet for this article.
June 12, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38863116/dynamic-individualized-risk-prediction-in-iga-nephropathy-entering-the-era-of-artificial-intelligence
#19
JOURNAL ARTICLE
Haresh Selvaskandan, Jonathan Barratt
No abstract text is available yet for this article.
June 12, 2024: Clinical Journal of the American Society of Nephrology: CJASN
https://read.qxmd.com/read/38863115/the-promise-and-challenges-of-metabolomic-studies-in-pediatric-ckd
#20
JOURNAL ARTICLE
Sahir Kalim, William E Smoyer
No abstract text is available yet for this article.
June 12, 2024: Clinical Journal of the American Society of Nephrology: CJASN
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