Bejoy Philip, Prerona Mukherjee, Yuti Khare, Pranav Ramesh, Sara Zaidi, Haytham Sabry, Amer Harky
INTRODUCTION: The SARS-CoV-2 virus caused a pandemic which affected healthcare delivery globally. Despite the presentation of COVID-19 infection being frequently dominated by respiratory symptoms; it is now notorious to also have potentially serious cardiovascular sequelae. This article explores current available data to provide a comprehensive overview of the pathophysiology, cardiovascular risk factors and implications of COVID-19. AREAS COVERED: The inherent structure of SARS-CoV-2, and its interaction with both ACE-2 and non-ACE-2 mediated pathways have been implicated in the development of cardiovascular manifestations, progressively resulting in acute respiratory distress syndrome, multiorgan failure, cytokine release syndrome and subsequent myocardial damage...
March 1, 2023: Expert Review of Cardiovascular Therapy