journal
https://read.qxmd.com/read/38030455/multidisciplinary-treatment-of-hepatocellular-carcinoma-in-2023-italian-practice-treatment-guidelines-of-the-italian-association-for-the-study-of-the-liver-aisf-italian-association-of-medical-oncology-aiom-italian-association-of-hepato-bilio-pancreatic-surgery
#1
Giuseppe Cabibbo, Bruno Daniele, Mauro Borzio, Andrea Casadei-Gardini, Umberto Cillo, Agostino Colli, Massimiliano Conforti, Vincenzo Dadduzio, Francesco Dionisi, Fabio Farinati, Ivan Gardini, Edoardo Giovanni Giannini, Rita Golfieri, Maria Guido, Andrea Mega, Silvia Minozzi, Fabio Piscaglia, Lorenza Rimassa, Laura Romanini, Anna Pecorelli, Rodolfo Sacco, Marta Scorsetti, Luca Viganò, Alessandro Vitale, Franco Trevisani
Worldwide, hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. The remarkable improvements in treating HCC achieved in the last years have increased the complexity of HCC management. Following the need to have updated guidelines on the multidisciplinary treatment management of HCC, the Italian Scientific Societies involved in the management of this cancer have promoted the drafting of a new dedicated document. This document was drawn up according to the GRADE methodology needed to produce guidelines based on evidence...
November 28, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38016896/anti-il23-in-inflammatory-bowel-disease-patients-with-dermatological-indication-the-shared-gastroenterological-dermatological-clinic-experience
#2
LETTER
Davide Giuseppe Ribaldone, Andrea Palumbo, Sara Susca, Martina Merli, Paolo Dapavo, Marta Venero
No abstract text is available yet for this article.
November 27, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38016895/diagnostic-accuracy-and-interobserver-agreement-of-cholangioscopy-for-indeterminate-biliary-strictures-a-single-center-experience
#3
JOURNAL ARTICLE
Sebastian Manuel Milluzzo, Rosario Landi, Vincenzo Perri, Pietro Familiari, Ivo Boškoski, Pia Clara Pafundi, Annarita Farina, Riccardo Ricci, Cristiano Spada, Guido Costamagna, Andrea Tringali
BACKGROUND AND STUDY AIMS: Characterization of indeterminate biliary strictures (IDBS) still represents a major challenge. Digital single-operator cholangioscopy (DSOC) could potentially overcome limits of conventional biopsy and brush sampling. The aim of this study was to compare diagnostic accuracy of visual evaluation and DSOC-guided biopsies to conventional trans-papillary sampling techniques and to evaluate the inter-observer agreement (IOA) on visual diagnosis. PATIENTS AND METHODS: All consecutive patients undergoing DSOC-guided biopsy after conventional sampling techniques for IDBS during a six-year period were retrospectively evaluated...
November 27, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38016894/reproducibility-and-accuracy-of-a-pocket-size-ultrasound-device-in-assessing-liver-steatosis
#4
JOURNAL ARTICLE
Andrea Costantino, Alessandra Piagnani, Riccardo Caccia, Andrea Sorge, Marco Maggioni, Riccardo Perbellini, Francesca Donato, Roberta D'Ambrosio, Nicole Piazza O Sed, Luca Valenti, Daniele Prati, Maurizio Vecchi, Pietro Lampertico, Mirella Fraquelli
BACKGROUND: This diagnostic prospective study compared the feasibility and diagnostic accuracy of Pocket-size Ultrasound Devices (PUDs) against standard ultrasound (US) in detecting liver steatosis using the controlled attenuation parameter (CAP) and liver biopsy as reference standards. MATERIALS AND METHODS: Consecutive patients with chronic liver diseases were assessed for the presence of steatosis using PUD and US. A CAP cut-off value >275 dB/m was applied to establish ≥S1...
November 27, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008699/feasibility-of-gallbladder-lesion-visualization-using-a-novel-ultrafine-peroral-cholangioscopy-a-preliminary-investigation
#5
JOURNAL ARTICLE
Lin Zhou, Yonghua Shen, Bing Xu, Hao Zhu, Ruhua Zheng, Dehua Tang, Peng Yan, Song Zhang, Xiaoping Zou, Lei Wang
BACKGROUND: Endoscopic visualization of gallbladder lesions by the traditional peroral cholangioscopy (POCS) during the endoscopic retrograde cholangiopancreatography process is challenging. In the present study, we evaluated the feasibility of a newly designed POCS with an ultrafine outer diameter that facilitates gallbladder visualization. METHODS: The novel POCS was designed and manufactured with an outer diameter of 7 French and achieved extremely high performance...
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008698/effect-of-a-monitored-exercise-protocol-in-cerebral-and-hepatic-hemodynamics-in-patients-with-cirrhosis-and-portal-hypertension
#6
JOURNAL ARTICLE
Ricardo U Macías-Rodríguez, Astrid Ruiz-Margáin, Berenice Román-Calleja, Carlos Cantú-Brito, Fernando Flores-Silva, Alejandro Gabutti-Thomas, Octavio Aguilar-Nájera, Mariana Cruz-Contreras, Lorena Weber-Sangri, Silvia Ríos-Torres, Aldo Torre Delgadillo, Carlos A Aguilar-Salinas, David Kershenobich-Stalnikowitz
BACKGROUND: Physical exercise (PE) has been proven to be beneficial in patients with cirrhosis; effects in cognitive function and cerebral hemodynamics, are yet to be explored. AIM: To evaluate the effects of a PE program (LFN-exercise protocol) in hepatic/cerebral hemodynamics. METHODS: Randomized open clinical trial in patients with cirrhosis; Control: Diet(n = 13),Intervention: Diet + exercise(n = 14) for 12 weeks...
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008697/glucose-and-lactate-levels-are-lower-in-eus-aspirated-cyst-fluid-of-mucinous-vs-non-mucinous-pancreatic-cystic-lesions
#7
JOURNAL ARTICLE
Gemma Rossi, Maria Chiara Petrone, Matteo Tacelli, Piera Zaccari, Stefano Crippa, Giulio Belfiori, Francesca Aleotti, Massimo Locatelli, Lorenzo Piemonti, Claudio Doglioni, Massimo Falconi, Gabriele Capurso, Paolo Giorgio Arcidiacono
BACKGROUND: Distinguishing mucinous (M) pancreatic cystic neoplasms (PCNs) from non-mucinous (NM) is challenging but crucial. Low intracystic glucose level has shown diagnostic tool promise, however further investigation is needed to understand metabolic processes. AIMS: To compare the diagnostic accuracy of intracystic glucose and CEA levels in a large cohort and explore lactate levels as potential marker. METHODS: PCNs≥15 mm which underwent EUS-fine needle aspiration were prospectively enrolled...
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008696/microbiota-and-ibd-current-knowledge-and-future-perspectives
#8
REVIEW
Caterina Foppa, Tommy Rizkala, Alessandro Repici, Cesare Hassan, Antonino Spinelli
Inflammatory Bowel Disease (IBD) is a chronic relapsing-remitting disease with a remarkable increase in incidence worldwide and a substantial disease burden. Although the pathophysiology is not fully elucidated yet an aberrant immune reaction against the intestinal microbiota and the gut microbial dysbiosis have been identified to play a major role. The composition of gut microbiota in IBD patients is distinct from that of healthy individuals, with certain organisms predominating over others. Differences in the microbial dysbiosis have been also observed between Crohn Disease (CD) and Ulcerative Colitis (UC)...
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008695/author-s-reply-tofacitinib-in-ulcerative-colitis-small-molecule-but-large-effect
#9
LETTER
Fabio Salvatore Macaluso, Ambrogio Orlando
No abstract text is available yet for this article.
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008694/cannabis-use-and-cyclic-vomiting-syndrome
#10
LETTER
Aravind Thavamani, Senthilkumar Sankararaman
None.
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38008693/otud7b-a-potential-therapeutic-target-in-the-treatment-of-gastric-cancer
#11
LETTER
Wei Zhai, Yan Jin
None.
November 25, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38000936/author-s-reply-aquaporin-1-in-cancer-oncogene-or-a-tumor-suppressor
#12
LETTER
Meng-Qi Zhuang, Hua-Bang Zhou, Yu-Bao Zhou
No abstract text is available yet for this article.
November 23, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/38000935/a-9-year-old-patient-with-indolent-nk-cell-lymphoproliferative-disorder-what-role-does-an-inherited-sesn3-mutation-play
#13
JOURNAL ARTICLE
Chengcheng He, Chuangzhen Lin, Mingsong Li, Yan Sun
No abstract text is available yet for this article.
November 23, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37989618/bacterial-infections-predispose-to-the-development-of-portal-vein-thrombosis-in-patients-with-decompensated-cirrhosis
#14
LETTER
Alberto Zanetto, Elena Campello, Paolo Simioni, Marco Senzolo
No abstract text is available yet for this article.
November 20, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37989617/lncrna-agap2-as1-in-cancer-an-insufficiently-explored-and-controversial-research-area
#15
LETTER
Hua-Wei Zhang, Li-Kai Shen
No abstract text is available yet for this article.
November 20, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37989616/tuberculous-peritonitis
#16
JOURNAL ARTICLE
Na Wu, Zhong Xu, Wei-Feng Huang
No abstract text is available yet for this article.
November 20, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37989615/a-huge-spleen-with-papillary-intralymphatic-angioendothelioma
#17
JOURNAL ARTICLE
Ting Li, Jiaao Yu, Xiaodong Sun, Guoyue Lv
No abstract text is available yet for this article.
November 20, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37985252/sieving-out-non-celiac-gluten-sensitivity-amongst-patients-with-irritable-bowel-syndrome
#18
JOURNAL ARTICLE
Anam Ahmed, Kunal Dixit, Alka Singh, Ashish Agarwal, Wajiha Mehtab, Shubham Prasad, Mahendra Singh Rajput, Ashish Chauhan, Ankit Agarwal, Shubham Mehta, Vineet Ahuja, Yogesh Shouche, Dhiraj Dhotre, Govind K Makharia
OBJECTIVES: It is challenging to make diagnosis of non-celiac gluten sensitivity/non-celiac wheat sensitivity (NCGS/NCWS) in clinical practice, since there is no biomarker and diagnosis is based on response to gluten-free-diet (GFD). We used anti-gliadin antibody (AGA) for screening patients with IBS for gluten-sensitivity. METHODS: 492 Adult-patients with IBS underwent screening for celiac disease and gluten-sensitivity using IgA anti-tissue transglutaminase antibody and IgA-AGA and IgG-AGA, respectively...
November 18, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37985251/analysis-of-exposome-and-genetic-variability-suggests-stress-as-a-major-contributor-for-development-of-pancreatic-ductal-adenocarcinoma
#19
JOURNAL ARTICLE
Giulia Peduzzi, Alessio Felici, Roberto Pellungrini, Francesca Giorgolo, Riccardo Farinella, Manuel Gentiluomo, Andrea Spinelli, Gabriele Capurso, Anna Monreale, Federico Canzian, Marco Calderisi, Daniele Campa
BACKGROUND: The current knowledge on pancreatic ductal adenocarcinoma (PDAC) risk factors is limited and no study has comprehensively tested the exposome in combination with the genetic variability in relation to the disease susceptibility. AIM: The aim of this study was to analyze the exposome and its interaction with known genetic susceptibility loci, in relation to PDAC risk. METHODS: A case-control study nested in UK Biobank cohort was conducted on 816 PDAC cases and 302,645 controls...
November 18, 2023: Digestive and Liver Disease
https://read.qxmd.com/read/37985250/magnetic-foreign-body-ingestion-in-pediatric-age
#20
JOURNAL ARTICLE
Paolo Quitadamo, Piergiorgio Gragnaniello, Sara Isoldi, Cristina Bucci, Francesco Esposito, Silvana Russo, Maria Giovanna Grella, Mariano Caldore
OBJECTIVES: To assess the clinical complications reported after the ingestion of magnetic foreign bodies (FBs) in pediatric age, along with their incidence among all FB ingestions and clinical presentation. STUDY DESIGN: We've consecutively recruited all children aged 0-14 years who were admitted for single or multiple magnet ingestion from May 2015 to December 2022. Patient demographics, admission sources and discharge status were accurately recorded, along with their clinical management and outcomes...
November 18, 2023: Digestive and Liver Disease
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