journal
https://read.qxmd.com/read/38760239/recurrence-rate-and-management-after-endoscopic-papillectomy-in-a-tertiary-referral-center
#1
JOURNAL ARTICLE
Lorenzo Dioscoridi, Durante Donnarumma, Edoardo Forti, Francesco Pugliese, Marcello Cintolo, Giulia Bonato, Marianna Bravo, Andrea Palermo, Massimiliano Mutignani
BACKGROUND AND STUDY AIMS: Endoscopic papillectomy (EP) is considered a safe procedure for ampullary lesions. Few data are available on management of residual and recurrent adenomas. The aims of the present study were to evaluate long-term recurrence rate, median time-to-recurrence after EP and treatment of both residual and recurrent adenomas. PATIENTS AND METHODS: Consecutive patients who underwent EP of major and minor papilla at our endoscopy center between 2011 and 2022 were enrolled...
May 16, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38755023/improved-outcomes-in-patients-with-non-variceal-upper-gastrointestinal-bleeding-while-undergoing-antithrombotic-therapy-a-propensity-score-matching-analysis
#2
JOURNAL ARTICLE
Fatih Acehan, Buket Karsavuranoğlu, Meryem Aslan, Cagdas Kalkan, Enes Seyda Sahiner, Osman Inan, Mustafa Comoglu, Yusufcan Yilmaz, Ihsan Ates
BACKGROUND: This study sought to examine the effect of antithrombotic use on clinical outcomes in non-variceal upper gastrointestinal bleeding (UGIB). METHODS: Patients consecutively diagnosed with non-variceal UGIB between February 2019 and September 2020 were divided into two groups based on their antithrombotic use: users and non-users. Using propensity score matching (PSM) and multivariable regression analyses, the impact of antithrombotic use prior to UGIB presentation on clinical outcomes was examined...
May 15, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38744558/inflammation-activity-affects-liver-stiffness-measurement-by-magnetic-resonance-elastography-in-masld
#3
JOURNAL ARTICLE
Xiaodie Wei, Shi Qi, Xinhuan Wei, Lixia Qiu, Xiaofei Du, Yali Liu, Hangfei Xu, Jinhan Zhao, Sitong Chen, Jing Zhang
BACKGROUND: Magnetic resonance elastography (MRE) is recognized as the most precise imaging technology for assessing liver fibrosis in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). We aimed to investigate the clinical factors and pathological characteristics that may impact LSM in MASLD patients. METHODS: This cross-sectional study recruited 124 patients who concurrently performed MRE, MRI-PDFF, and biopsy-proven MASLD. Linear regression models, Spearman's correlation, and subgroup analysis were employed to identify the variables affecting LSM...
May 13, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38744557/computer-aided-diagnosis-system-for-optical-diagnosis-of-colorectal-polyps-under-white-light-imaging
#4
JOURNAL ARTICLE
Yaxuan Cheng, Longsong Li, Yawei Bi, Song Su, Bo Zhang, Xiuxue Feng, Nanjun Wang, Wengang Zhang, Yi Yao, Nan Ru, Jingyuan Xiang, Lihua Sun, Kang Hu, Feng Wen, Zixin Wang, Lu Bai, Xueting Wang, Runzi Wang, Xingping Lv, Pengju Wang, Fanqi Meng, Wen Xiao, Enqiang Linghu, Ningli Chai
OBJECTIVES: This study presents a novel computer-aided diagnosis (CADx) designed for optically diagnosing colorectal polyps using white light imaging (WLI).We aimed to evaluate the effectiveness of the CADx and its auxiliary role among endoscopists with different levels of expertise. METHODS: We collected 2,324 neoplastic and 3,735 nonneoplastic polyp WLI images for model training, and 838 colorectal polyp images from 740 patients for model validation. We compared the diagnostic accuracy of the CADx with that of 15 endoscopists under WLI and narrow band imaging (NBI)...
May 13, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38744556/endoscopic-resection-of-extra-luminal-gastric-gastrointestinal-stromal-tumors-using-a-snare-assisted-external-traction-technique-with-video
#5
JOURNAL ARTICLE
Jing-Wen Zhang, Chang-Qing Guo, Shan-Shan Zhu, Nan Dai, Ping Liu, Fang-Bin Zhang, Hai-Ning Zhou, Jian-Feng Wang, Si-Su Zhou, Xin-Guang Cao
OBJECTIVE: The primary purpose of the study was to explore the clinical efficacy of the novel snare assisted endoscopic resection of extraluminal growing gastric gastrointestinal stromal tumors (gastric GISTs) using external traction, and the secondary purpose was to compare the novel snare assisted endoscopic resection of extraluminal GISTs with the standard laparoscopic procedure. METHODS: We retrospectively analyzed the patients who underwent novel external traction assisted endoscopic resection or laparoscopic resection for their extraluminal gastric GIST ≤5 cm in diameter...
May 13, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38735797/evaluating-the-efficacy-of-gipr-agonists-on-non-alcoholic-fatty-liver-disease-a-mediation-mendelian-randomization-study
#6
JOURNAL ARTICLE
Siyuan Xie, Delong Chen, Yangke Cai, Liyi Xu, Oulan Liao, Xuan Jia, Xiaowei Ji, Hanwen Chen, Jianshan Mao, Jianting Cai
OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease worldwide while still lacks drugs for treatment or prevention. We aimed to investigate the causal role of glucose-dependent insulinotropic polypeptide receptor agonists (GIPRAs) on NAFLD and identify the mediated risk factors by which GIPRAs exert their therapeutic effects. METHODS: Genetic proxies of GIPRAs were identified as cis-SNPs of GIPR associated with both the gene expression level and HbA1c and analyses including colocalization and linkage disequilibrium (LD) were performed for validation...
May 11, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38735796/non-coding-transcribed-ultraconserved-region-uc-290-in-colon-mucosa-promotes-intestinal-fibrosis-in-chronic-active-ulcerative-colitis
#7
JOURNAL ARTICLE
Xiao Xian Qian
BACKGROUND AND AIMS: TGF-β1 induces epithelial-mesenchymal transition (EMT) and leads to intestinal fibrosis in ulcerative colitis (UC). We aimed to investigate the expression of transcribed ultraconserved region uc.290 in chronic UC and its role in intestinal fibrosis. METHODS: Colon specimens were taken from thirty chronic active UC, chronic inactive UC and healthy controls respectively. Modified Mayo score, expressions of uc.290, TGF-β1, EMT biomarkers (Vimentin, α-SMA and E-cadherin) and intestinal fibrosis biomarker (collagen Ⅲ) in colon biopsy specimens were determined in human...
May 11, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38735795/off-label-use-of-lumen-apposing-metal-stents-for-treatment-of-short-benign-biliary-strictures
#8
JOURNAL ARTICLE
Massimiliano Mutignani, Mario Capasso, Giulia Bonato, Francesco Pugliese, Lorenzo Dioscoridi, Marcello Cintolo, Marianna Bravo, Andrea Palermo, Irene Cottone, Edoardo Forti
BACKGROUND: Endoscopic stenting is the mainstay of treatment for benign biliary strictures. There is a not-negligible rate of recurrence and stent migration. Lumen-apposing metal stents (LAMS) have a unique design with short length, large diameter and wide flanges which make them less prone to migration. AIMS: To describe the intraluminal use of LAMS to treat short benign biliary strictures. METHODS: All consecutive patients who underwent bi-flanged LAMS placement for benign biliary strictures, in approximately 6 years, were retrospectively included...
May 11, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38734569/unveiling-the-enigma-of-recurrent-gastrointestinal-bleeding-a-case-of-light-chain-amyloidosis-diagnosed-through-repeated-colonoscopies
#9
JOURNAL ARTICLE
Yi-Chen Qi, Jian-Ming Zhou, Dian Gao, Qiong-Fang Yu
No abstract text is available yet for this article.
May 10, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38734568/intrahepatic-cholangiocarcinoma-with-fgfr-alterations-a-series-of-chinese-cases-with-an-emphasis-on-their-clinicopathologic-and-genetic-features
#10
JOURNAL ARTICLE
Jun Zhou, Haoran Yu, Hong Zeng, Qin Shen, Xuewen Wang, Qinxin Xia
Intrahepatic Cholangiocarcinoma (iCCA) with FGFR alterations is relatively rare, and its identification is important in the era of targeted therapy. We collected a large series of FGFR-altered cases in the Chinese population and characterized their clinicopathological and genetic features. Among the 18 FGFR-altered cases out of 260 iCCAs, 10 were males and 8 were females, ranging in age from 35 to 74 years (mean, 57.3 years; median, 58 years). Pathologically, they include 9 cases of large duct (LD, 50 %) and small duct (SD, 50 %) types each...
May 10, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38734567/ileocaecal-crohn-s-disease-to-resect-or-not-to-resect-is-that-the-question
#11
JOURNAL ARTICLE
Imerio Angriman, Gianluca M Sampietro
No abstract text is available yet for this article.
May 10, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38729903/post-liver-transplant-short-term-and-survival-outcomes-in-patients-living-with-obesity
#12
JOURNAL ARTICLE
Ramanpreet Bajwa, Lovepreet Singh, Sofia Molina Garcia, Kristelle Imperio-Lagabon, Omar T Sims, Jamak Modaresi Esfeh
The objectives of our study were to examine and compare patient and graft survival over a 5-year period across BMI groups, and examine immediate and short-term complications post-LT. This was a retrospective study that examined all liver transplants that occurred at our institution between January 2015-October 2022. Patients were divided into 4 BMI groups (n = 888): normal-overweight (BMI 18.5- 29.9 kg/m2 ), class I obesity (BMI 30-34.9 kg/m2 ), class II obesity (BMI 35-39.9 kg/m2 ), and class III obesity (BMI ≥40 kg/m2 ) patients...
May 9, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38729902/superior-bowel-preparation-quality-for-colonoscopy-with-1l-peg-compared-to-2l-peg-and-picosulphate-data-from-a-large-real-world-retrospective-outpatient-cohort
#13
JOURNAL ARTICLE
Davide Scalvini, Marco Vincenzo Lenti, Stiliano Maimaris, Francesca Lusetti, Eleonora Alimenti, Erica Fazzino, Aurelio Mauro, Stefano Mazza, Simona Agazzi, Elena Strada, Laura Rovedatti, Marco Bardone, Lodovica Pozzi, Annalisa Schiepatti, Antonio Di Sabatino, Federico Biagi, Andrea Anderloni
BACKGROUND: Several randomized clinical trials comparing different bowel preparations (BP) have shown similar efficacy; however, there is a lack of real-world studies on this topic. AIMS: This study aims to identify the most effective BP regimen in a real-world setting and any predictors of inadequate BP. METHODS: A retrospective single-center study was conducted over 14 months at an academic hospital including outpatient colonoscopies in which adult patients did not teach on how to perform BP before colonoscopy...
May 9, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38724344/textbook-outcome-of-laparoscopic-hepatectomy-in-the-context-of-precision-surgery-a-single-center-experience
#14
JOURNAL ARTICLE
Zejiang Xu, Yaqing Lv, Hao Zou, Yuanfang Jia, Wenhao Du, Jinbin Lu, Yang Liu, Zemin Shao, Hao Zhang, Chuandong Sun, Chengzhan Zhu
OBJECTIVE: Laparoscopic hepatectomy (LH) has become a common surgery for the treatment of liver tumor. To evaluate the surgical quality of laparoscopic hepatectomy under the context of precision surgery with Textbook outcome (TO), a comprehensive and holistic assessment approach. METHODS: A total of 1056 patients who underwent laparoscopic hepatectomy from May 2016 and December 2022 were enrolled in the study. All the patients were performed hepatectomy. The rate of TO and factors associated with achieving TO were examined...
May 8, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38719629/the-histopathology-of-very-early-onset-ibd
#15
LETTER
Vincenzo Villanacci, Patrizia Alvisi, Rachele Del Sordo, Maurizio Fuoti, Sara Mino
No abstract text is available yet for this article.
May 7, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38719628/clinical-and-genetic-factors-involved-in-porto-sinusoidal-vascular-disorder-after-oxaliplatin-exposure
#16
JOURNAL ARTICLE
A Puente, J I Fortea, C Del Pozo, M Serrano, M Alonso-Peña, A Giráldez, L Tellez, J Martinez, M Magaz, L Ibañez, J Garcia, E Llop, C Alvarez-Navascues, M Romero, E Rodriguez, M T Arias Loste, A Antón, V Echavarria, C López, A Albillos, V Hernández-Gea, J C Garcia-Pagán, R Bañares, J Crespo
BACKGROUND AND AIMS: Oxaliplatin (OX) has been described as a potential etiologic agent for porto-sinusoidal vascular disorder (PSVD). Our aim was to describe the natural history of PSVD due to OX in colon cancer (CRC) and identify risk factors for its development. METHODS: We made a multicenter retrospective case-control (ratio 1:3) study with patients diagnosed of PSVD-OX. Baseline data, end of treatment, years of follow-up and diagnosis of PSVD were collected and compared to controls (without PSVD)...
May 7, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38714377/a-rare-case-of-leiomyosarcoma-of-pancreatic-head
#17
JOURNAL ARTICLE
Jia-Bei Liu, Peng Liu
No abstract text is available yet for this article.
May 6, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38705783/mmx-mesalamine-in-ulcerative-colitis-major-advantages-towards-classical-mesalamine-formulations
#18
REVIEW
Ferdinando D'Amico, Francesca Lusetti, Laurent Peyrin-Biroulet, Silvio Danese
Medical therapy is the cornerstone of ulcerative colitis (UC) management and aims to induce and maintain remission. In case of mild-to-moderate UC, mesalamine (5-ASA) is the first-line option. 5-ASA requires local release at the level of the inflamed mucosa to exert its therapeutic action. While rectal preparations are useful in distal colitis, in cases of UC of at least rectosigmoid extent, guidelines suggest the association of oral and rectal 5-ASA. Mesalamine with Multi Matrix System® technology (MMX mesalamine) is an oral, high-strength (1...
May 4, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38705782/host-related-low-prevalence-gastritides-epidemiological-and-clinical-characterization
#19
JOURNAL ARTICLE
Robert M Genta, Massimo Rugge
INTRODUCTION: A recent consensus meeting (RE.GA.IN) addressed "host-related, low-prevalence gastritis": eosinophilic (EoG), lymphocytic (Hp-pos_LyG and Hp-neg_LyG), collagenous (CollG), and granulomatous gastritis (GrG). Our study evaluates their clinico-epidemiological characteristics. MATERIALS AND METHODS: We extracted all patients with a diagnosis of EoG, LyG, CollG, and GrG from a clinicopathological database and compared their demographics, clinical and endoscopic characteristics, associated conditions, and clinical awareness to those of all other subjects in the database (controls)...
May 4, 2024: Digestive and Liver Disease
https://read.qxmd.com/read/38693033/gastroblastoma-with-an-actb-gli1-gene-fusion-in-a-39-year-old-man
#20
JOURNAL ARTICLE
Lei Huang, Die Hu, Hongjin Hua, Xinmin Si
No abstract text is available yet for this article.
April 30, 2024: Digestive and Liver Disease
journal
journal
35085
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.