Maria D Santi, Diego Carvalho, Rosina Dapueto, Manuela Bentura, Maia Zeni, Loreto Martínez-González, Ana Martínez, Mariana A Peralta, Ana Rey, Javier Giglio, Maria G Ortega, Eduardo Savio, Juan A Abin-Carriquiry, Florencia Arredondo
Alzheimer's disease (AD) involves a neurodegenerative process that has not yet been prevented, reversed, or stopped. Continuing with the search for natural pharmacological treatments, flavonoids are a family of compounds with proven neuroprotective effects and multi-targeting behavior. The American genus Dalea L. (Fabaceae) is an important source of bioactive flavonoids. In this opportunity, we tested the neuroprotective potential of three prenylated flavanones isolated from Dalea species in a new in vitro pre-clinical AD model previously developed by us...
April 5, 2024: Neurotoxicity Research